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Changes in peak inspiratory flow rate and peak airway pressure with endotracheal tube size during chest compression

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World Journal of Emergency Medicine 2020年第2期11卷 97-101页

作者： Jung Wan kim Jin Woong Lee Seung Ryu Jung Soo Park InSool Yoo Yong Chul Cho Hong Joon ahn Department of Emergency Medicine Chungnam National University HospitalJung-guDaejeonRepublic of Korea Department of Emergency Medicine College of MedicineChungnam National UniversityJung-guDaejeonRepublic of Korea

BACKGROUND:Adequate airway management plays an important role in high-quality cardiopulmonary resuscitation(CPR).Airway management is usually performed using an endotracheal tube(ETT)during ***,no study has assessed the effect of ETT size on the fl ow rate and airway pressure during ***:We measured changes in peak inspiratory fl ow rate(PIFR),peak airway pressure(Ppeak),and mean airway pressure(Pmean)according to changes in ETT size(internal diameter 6.0,7.0,and 8.0 mm)and with or without CPR.A tidal volume of 500 mL was supplied at a rate of 10 times per minute using a mechanical *** compressions were maintained at a constant compression depth and speed using a mechanical chest compression device(LUCAS2,mode:active continuous,chest compression rate:102±2/minute,chest compression depth 2–2.5 inches).RESULTS:The median of several respiratory physiological parameters during CPR was significantly different according to the diameter of each ETT(6.0 vs.8.0 mm):PIFR(32.1 L/min[30.5–35.3]vs.28.9 L/min[27.5–30.8],P<0.001),Ppeak(48.84 cmH2O[27.46–52.11]vs.27.45 cmH2O[22.53–52.57],P<0.001),and Pmean(18.34 cmH2O[14.61–21.66]vs.13.66 cmH2O[8.41–19.24],P<0.001).CONCLUSION:The changes in PIFR,Ppeak,and Pmean were related to the internal diameter of ETT,and these values tended to decrease with an increase in ETT *** airway pressures were measured in the CPR group than in the no CPR group.

关键词： Cardiopulmonary resuscitation Intratracheal intubation Airway pressure

Folding and Unfolding Simulations of a Three-Stranded Beta-Sheet Protein

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Journal of Materials Science and Chemical Engineering 2016年第1期4卷 13-17页

作者： Seung-Yeon kim School of Liberal Arts and Sciences Korea National University of Transportation Chungju Republic of Korea

Understanding the folding processes of a protein into its three-dimensional native structure only with its amino-acid sequence information is a long-standing challenge in modern science. Two- hundred independent folding simulations (starting from non-native conformations) and two- hundred independent unfolding simulations (starting from the folded native structure) are performed using the united-residue force field and Metropolis Monte Carlo algorithm for betanova (three-stranded antiparallel beta-sheet protein). From these extensive computer simulations, two representative folding pathways and two representative unfolding pathways are obtained in the reaction coordinates such as the fraction of native contacts, the radius of gyration, and the root- mean-square deviation. The folding pathways and the unfolding pathways are similar each other. The largest deviation between the folding pathways and the unfolding pathways results from the root-mean-square deviation near the folded native structure. In general, unfolding computer simulations could capture the essentials of folding simulations.

关键词： Protein Folding Unfolding Computer Simulation

Orthotic approach to prevention and management of diabetic foot:A narrative review

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World Journal of Diabetes 2022年第11期13卷 912-920页

作者： Min Cheol Chang Yoo Jin Choo In Sik Park Myung Woo Park Du Hwan kim Rehabilitation Medicine Yeungnam UniversityDaegu 42415South Korea Korean Podiatry and Pedorthics Institute Goyang 10442South Korea Physical Medicine and Rehabilitation Chung-Ang UniversitySeoul 06973South Korea

Diabetic foot is a common complication affecting more than one-fifth of patients with *** not treated in time,it may lead to diabetic foot ulcers or Charcot *** the management of diabetic foot,shoe modifications and orthoses can be used to reduce pressure on the affected foot or provide the foot with increased *** addition,the shoe modifications and orthotic devices can relieve patient discomfort during *** shoe modifications include changing the insole material,modifying the heel height,adding a steel shank or rocker sole,and using in-depth ***,a walking brace or ankle-foot orthosis can be used to reduce the pressure on the affected *** purpose of this narrative review was to provide a reference guide to support clinicians in prescribing shoe modifications and foot orthoses to treat diabetic foot ulcers and Charcot arthropathy.

关键词： Diabetic foot Foot ulcers Charcot arthropathy Shoes Foot orthosis

An insert in the Hpy region of hscp in Hefiothis virescens （Lepidoptera： Noctuidae） reveals a possible CORE-SINE of insects

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Insect Science 2009年第3期16卷 219-226页

作者： Sujin Park Thomas M. Brown Sam-Kyu kim Chunkeun Lim Jang Hyun Hur Yong Chul Park Saeyoull Cho Life Science Institute University of Michigan Ann Arbor M148109 USA Genectar Corn LLC 539 Kafispell Ave. Whitefish MT 59937-2743 USA Division of Biological Environment College of Agriculture and Life Science Kangwon National University Chuncheon 200-701Korea Department of Appfied Biology Division of Bio-resource of Technology College of Agriculture and Life Science Kangwon National University Chuncheon 200-701 Korea Department of Plant Biotechnology Program Division of Biotechnology School of BiotechnologyInstitute of Bioscience and Biotechnology Kangwon National University Chuncheon 200-701 Korea

A new putative transposon was identified in the tobacco budworm, Helio- this virescens. This transposon was characterized as a full length CORE-SINE （65 bp of ＂CORE＂ core specific nucleotide short interspersed elements） that resembled sequences from three other lepidopterans and humans. In particular, the A-box and B-box regions of this sequence most closely conformed to the signature of CORE-SINEs from widely divergent species. This CORE-SINE was present as a polymorphism in a hypervariable region of the gene hscp, which is the target of pyrethroid insecticides and other xenobiotics in the nerve axon. We described this new putative transposon as Noct-1 due to its presence in a noctuid moth. This is the first description of a full-length CORE-SINE with the A-box, B-box, target site duplication, and candidate core domain from an insect.

关键词： A-box B-box CORE-SINE Heliothis virescens Noct-1 target site duplication

Lycium barbarum polysaccharides related RAGE and Aβ levels in the retina of mice with acute ocular hypertension and promote maintenance of blood retinal barrier

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Neural Regeneration Research 2020年第12期15卷 2344-2352页

作者： Xue-Song Mi Qian Feng Amy Cheuk Yin Lo Raymond Chuen-Chung Chang Sookja kim Chung Kwok-Fai So Department of Ophthalmology the First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong ProvinceChina Guangdong-Hong Kong-Macao Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina Changsha Academician Expert Workstation Aier Eye Hospital GroupChangshaHunan ProvinceChina State Key Laboratory of Brain and Cognitive Sciences Hong Kong Special Administrative RegionChina Department of Ophthalmology The University of Hong KongHong Kong Special Administrative RegionChina Faculty of Medicine Macao University of Science and TechnologyMacao Special Administrative RegionChina School of Biomedical Science LKS Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina

Our previous study verified the protective effects of Lycium barbarum polysaccharides(LBP)on retinal neurons and blood vessels in acute ocular hypertension(AOH)*** investigate the effect of LBP on the reactivity of retinal glial cells,an AOH mouse model was established in one eye by maintaining ocular hypertension of 90 mm Hg for 60 *** LBP solution(1 mg/kg)or phosphate-buffered saline was administrated to the mice by gavage daily,starting 7 days before the AOH insult and continuing until the mice were sacrificed for specimen collection on day 4 *** AOH insult,increased numbers of astrocytes and microglia were observed,together with decreased expression of the following glial cell biomarkers in the retinal ganglion cells of AOH mice:glial fibrillary acidic protein,glutamine synthetase,aquaporin-4,S-100 proteins,ionized calcium-binding adaptor molecule 1,amyloid precursor protein and receptor of advanced glycosylation *** intervention with LBP,the above changes were significantly ***,morphological remodeling of blood vessel-associated retinal astrocytes,marked by glial fibrillary acidic protein,was also *** results,taken together,suggest that LBP regulated the production of amyloid-βand expression of receptor of advanced glycosylation end-products,as well as mediating the activity of retinal glial cells,which may lead to the promotion of better maintenance of the blood-retinal barrier and improved neuronal survival in AOH *** study was approved by the Committee for the Use of Live Animals in Teaching and Research(approval ***-#1664-08).

关键词： astrocyte blood-retinal barrier glial cell Lycium barbarum microglia model plasticity remodel retina

Partial Fraction Decomposition by Repeated Synthetic Division

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American Journal of Computational Mathematics 2016年第2期6卷 153-158页

作者： Youngsoo kim Byunghoon Lee Department of Mathematics Tuskegee University Tuskegee AL USA

We present an efficient and elementary method to find the partial fraction decomposition of a rational function when the denominator is a product of two highly powered linear factors.

关键词： Partial Fraction Decomposition Synthetic Division Heaviside Coverup

Shifting Nicotiana attenuata's diurnal rhythm does not alter its resistance to the specialist herbivore Manduca sexta

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Journal of Integrative Plant Biology 2016年第7期58卷 656-668页

作者： Jasmin Herden Stefan Meldau Sang-Gyu kim Grit Kunert Youngsung Joo lan T.Baldwin Meredith C.Schuman Department of Molecular Ecology Max Planck Institute for Chemical EcologyHans-Knoell-Strasse 807745 JenaGermany Department of Biochemistry Max Planck Institute for Chemical EcologyHans-Knoell-Strasse 807745 JenaGermany German Centre for Integrative Biodiversity Research(iDiv) DeutscherPlatz 5e04103 LeipzigGermany Ecology Department of BiologyUniversity of KonstanzUniversitatsstrasse lOD 78457 KonstanzGermany KWS SAAT AG Grimsehlstrasse 31Postfach 146337555 EinbeckGermany Center for Genome Engineering Institute of Basic ScienceDaejeonKorea

Arabidopsis thaliana plants are less resistant to attack by the generalist lepidopteran herbivore Trichoplusia ni when plants and herbivores are entrained to opposite, versus identical diurnal cycles and tested under constant conditions. This effect is associated with circadian fluctuations in levels of jasmonic acid, the transcription factor MYC2, and glucosinolate contents in leaves. We tested whether a similar effect could be observed in a different plant-herbivore system： the wild tobacco Nicotiana attenuata and its co-evolved specialist herbivore, Manduca sexta. We measured larval growth on plants under both constant and diurnal conditions following identical or opposite entrainment, profiled the metabolome of attacked leaf tissue, quantified specific metabolites known to reduce M. sexta growth, and monitored A/I. sexta feeding activity under all experimental conditions. Entrainment did not consistently affect NI. sexta growth or plant defense induction. However, both were reduced under constant dark conditions,as was M. sexta feeding activity. Our data indicate that the response induced by NI. sexta in N. attenuata is robust to diurnal cues and independent of plant or herbivore entrain- ment. We propose that while the patterns of constitutive or general damage-induced defense may undergo circadian fluctuation, the orchestration of specific induced responses is more complex.

关键词： Circadian clock diurnal rhythm Manduca sexta Nicotiana attenuate plant-herbivore interactions

Superhydrophobic and antireflective nanograss-coated glass for high performance solar cells

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Nano Research 2014年第5期7卷 670-678页

作者： Hyo Jin Gwon Yensil Park Cheon Woo Moon Sahn Nahm Seok-Jin Yoon Soo Young kim Ho Won Jang Electronic Materials Research Center Korea Institute of Science and Technology Seou1136-791 Korea Department of Materials Science and Engineering Korea University Seoul 136-701 Korea School of Chemical Engineering and Materials Science Chung-Ang University Seou1156-756 Korea Department of Materials Science and Engineering Research Institute of Advanced Materials Seoul National University Seou1151-744Korea

We present a facile method for producing superhydrophobic nanograss-coated （SNGC） glass surfaces that possess both reduced reflectivity and self-cleaning properties at the air/glass interface. The refractive index of a CaF2 nanograss （NG） layer on a glass substrate, deposited by glancing angle vapor deposition, is 1.04 at 500 nm, which is the second-lowest value ever reported so far. The fluorinated NG layer gives rise to a high water contact angle （〉150°） and very efficient cleaning out of dust with water drops. Using the dual functionalities of the SNGC glass, we demonstrate superhydrophobic and antireflective organic photovoltaic cells with excellent power conversion efficiency.

关键词： superhydrophobic antireflective self-cleaning nanograss solar cells glancing angle deposition

Synthesis and Gas Sensing of TiO_2 Ultrafine Powders by Precipitating

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稀有金属材料与工程 2006年第A3期35卷 163-164页

作者： Min-Hyun Seo Bong-Ho Lee Jong-Won kim Gi-Hong Rue Duk-Dong Lee Jeung-Soo Huh Department of Sensor and Display Engineering Kyungpook National UniversitySangyuk-DongBukguDaegu 1370Korea Department of Materials Science and Metallurgy Kyungpook National UniversitySangyuk-DongBukguDaegu 1370Korea Department of Nano-science and Technology Kyungpook National UniversitySangyuk-DongBukguDaegu 1370Korea School of Electronic Engineering Kyungpook National UniversitySangyuk-DongBukguDaegu 1370Korea Department of Sensor and Display Engineering Kyungpook National UniversitySangyuk-DongBukguDaegu 1370Korea.Department of Nano-science and TechnologyKyungpook National UniversitySangyuk-DongBukguDaegu 1370Korea

We investigated the gas sensing characteristics of rutile and anatase TiO_2 nano-particle sensors for chemical warfare ***_2 nano-powders with rutile and anatase structure were fabricated by controlling pH value without heat treatment *** mean particle size of TiO_2 powders were below 10 ***-prepared TiO_2 powders have several advantages of nano particle size and high surface area and could be a prominent candidate for ***_2 sensors were examined with DMMP for chemical warfare agents detection.

关键词： TiO2 chemical warfare agents sensor nano-sensor pH