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3-Phase hierarchical graphene-based epoxy nanocomposite laminates for automotive applications

Journal of Materials Science & Technology 2019年第10期35卷 2169-2177页

作者： Ahmed Elmarakbi Panagiotis Karagiannidis Alessandra Ciappa Franco Innocente Francesco Galise Brunetto Martorana Francesco Bertocchi Francesco Cristiano elvira Villaro Abalos Julio Gomez Department of Mechanical and Construction Engineering Faculty of Engineering and EnvironmentNorthumbria UniversityNewcastleNE18STUnited Kingdom School of Engineering Faculty of TechnologyUniversity of SunderlandSunderlandSR6 ODDUnited Kingdom Delta-Tech S.pA. localita Rifoglieto 60/a-int.155011AltopascioLUItaly Fiat Research Center via ex Aeroporto80038 Pomigliano d'ArcoNaplesItaly Nanesa srl.Via Del Gavardello 59/c 52100 ArezzoARItaly Instituto de Tecnologfas Quimicas Emergences de La Rioja Antonio de Nebrija826006 LogronoSpain Avanzare Innovacion Tecnologica S.L Avda.Lentiscares 4-626370 NavarreteSpain

Two different types of graphene flakes were produced following solution processing methods and dispersed using shear mixing in a bifunctional(A) and a multifunctional(B) epoxy resin at a concentration of 0.8 and 0.6 wt%, respectively. The graphene/epoxy resin mixtures were used to impregnate unidirectional carbon fibre tapes. These prepregs were stacked(seven plies) and cured to produce *** interlaminar fracture toughness(mode-I) of the carbon fiber/graphene epoxy laminates with resin B showed over 56% improvement compared with the laminate without graphene. Single lap joints were prepared using the laminates as adherents and polyurethane adhesives(Sika 7666 and Sika 7888). The addition of graphene improved considerably the adhesion strength from 3.3 to 21 MPa(sample prepared with resin A and Sika 7888) highlighting the potential of graphene as a secondary filler in carbon fibre reinforced polymer composites.

关键词： Graphene Carbon fibre reinforced polymer(CFRP) Fracture toughness Shear lap joints

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Haplotype analysis of CLDN19 single nucleotide polymorphisms in Spanish patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis

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World Journal of Pediatrics 2015年第3期11卷 272-275页

作者： Ernesto Martin-Nunez Elizabeth Cordoba-Lanus Hilaria Gonzalez-Acosta Aniana Oliet elvira Izquierdo Felix Claverie-Martin Unidad de Investigacion Hospital Nuestra Senora de CandelariaSanta Cruz de TenerifeSpain Servicio de Nefrologia Hospital Severo OchoaMadridSpain Nefrologia Infantil Hospital General Gregorio MaranonMadridSpain

Background:Familial hypomagnesemia with hypercalciuria and nephrocalcinosis(FHHNC)is an autosomal recessive tubular disease caused by mutations in the CLDN16 or CLDN19 *** studies using microsatellite markers flanking the CLDN19 locus estimated that p.G20D(c.59G>A),a recurrent mutation in Spanish families,is a founder *** the present study,we assessed the haplotype of Spanish patients using single nucleotide polymorphisms(SNPs).Methods:Twenty-seven FHHNC patients were included in this *** analyzed four SNPs located in CLDN19 introns 3 and 4 by polymerase chain reaction amplification and DNA ***:Three new patients with homozygous p.G20D were *** SNP genotyping analysis showed that alleles carrying this mutation shared a common SNP ***:Our findings suggest the existence of a founder effect responsible for FHHNC in our *** for the presence of mutation p.G20D should be the first genetic screening in Spanish patients.

关键词： chronic kidney disease founder effect gene mutation nephrocalcinosis

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A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication

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World Journal of Gastroenterology 2014年第6期20卷 1438-1449页

作者： elvira Garza-González Guillermo Ignacio Perez-Perez Héctor Jesús Maldonado-Garza Francisco Javier Bosques-Padilla Servicio de Gastroenterología y Departamento de Patología Clínica Hospital Universitario "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León Departments of Medicine and Microbiology New York University School of Medicine

Helicobacter pylori (H. pylori) affects nearly half of the world’s population and, thus, is one of the most frequent and persistent bacterial infections worldwide. H. pylori is associated with peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic methods exist to detect infection, and the choice of one method or another depends on several factors, such as accessibility, advantages and disadvantages of each method, cost, and the age of patients. Once H. pylori infection is diagnosed, the clinician decides whether treatment is necessity, according to the patient’s clinical condition. Typically, eradication of H. pylori is recommended for treatment and prevention of the infection. Cure rates with the standard triple therapy are acceptable, and effective quadruple therapies, sequential therapies, and concomitant therapies have been introduced as key alternatives to treat H. pylori infection. In this work, we review the main diagnostic methods used to identify H. pylori infection and to confirm eradication of infection. In addition, key factors related to treatment are reviewed.

关键词： Diagnosis Helicobacter pylori Treatment Hybrid therapy Concomitant therapy Sequential therapy

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A Simple Procedure to Fabricate Paper Biosensor and Its Applicability-NADH/NAD＊ Redox System

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Journal of Pharmacy and Pharmacology 2018年第2期6卷 175-187页

作者： Isabel Ribau elvira Fortunato Departamento de Ciencias dos Materiais Faculdade de Ciencias e Tecnologia Universidade Nova de Lisboa Campus de Caparica Caparica 2829-516 Portugal

A simple device which incorporates three electrodes （working electrode, counter electrode and reference electrode） was constructed to be used currently in laboratories without elevated cost. It does not need more than 2 μL of electrolyte, sample or working solution, his support material is paper, and the working electrode which is based on carbon ink can incorporate enzymes and cofactors. To test this concept we started this investigation using the NADH/NAD＋ redox couple which is an onmipresent coenzyme in living systems but is also a challenge to electrochemistry. The paper sensor fabrication was simple, rapid and cheaper. NADH was incorporated in the carbon ink by mixing both and, this mixture was used to print the working electrode. The direct electrochemical system NADH/NAD＋ signal obtained, using this device, appeared at low potentials. A quasi-reversible diffusional redox process was achieved and regeneration of the NADH after oxidation was reached. This small paper device was not only used to study the redox process of NAD＋/NADH, but also its behavior in the presence of electroactive （ascorbic acid） and non-eletroactive species （glucose）.

关键词： NADH/NAD+ screen-printing biosensor paper device.

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Evaluation of Pedestrian–Train Fatalities in the State of Maryland: A 5‑Year Retrospective Study

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Journal of Forensic Science and Medicine 2020年第4期6卷 135-139页

作者： elvira Carias Claire Hammerschmidt Taylor Hall Xiang Zhang Rebecca Phipps Ling Li Office of the Chief Medical Examiner State of MarylandBaltimoreMarylandUSA Master of Science in Forensic Medicine Program Graduate Schoolat University of Maryland BaltimoreBaltimoreMarylandUSA

Few studies have been done on the incidences of train-related pedestrian fatalities throughout the United States,with no previous studies reported in the State of Maryland.A retrospective study was conducted at the statewide medical examiner’s office in Maryland to evaluate the characteristics of train-related pedestrian fatalities from 2014 to *** aim of the study was to analyze circumstances of deaths through the medicolegal death investigation and postmortem examination findings,including toxicological study,to help identify epidemiological characteristics of pedestrian–train‑related fatalities.A total of 48 pedestrian-train deaths were *** the 48 cases identified,21 deaths(43.75%)were determined to be accident,20 deaths(41.67%)were suicide,and 7 deaths(14.58%)whose manner of death could not be *** the 21 accidental victims,17 were male and 4 were female(M:F ratio=4.3:1),11(52.38%)were white,6(28.57%)African American,and 4 Hispanic(19.05%),with age ranging from 16 to 58 years(mean age=35).Of the 20 suicide victims,17 were males and 3 females(M:F ratio=5.7:1),16(80%)were white,2(10%)African American,and 2(10%)Hispanic,with age ranging from 22 to 60 years(mean age=40).The majority of accidents occurred during weekday evening rush hours between 4:00 pm and 7:00 pm,while the suicides showed no specific time *** specific peak for seasons of year was found in suicides or *** toxicological studies showed that 52.38%(11/21 cases)of accidental victims were positive for alcohol and 30%(6/20 cases)of suicide victims were positive for *** of death could not be determined in 7 cases because of unclear circumstances of *** death scene investigation and complete postmortem examination,including comprehensive toxicological testing,is very important in all train-related pedestrian *** the manner of death can directly affect the outcome of civil ligation and dispersal of insurance ***

关键词： Pedestrian train accident suicide forensic investigation

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Spontaneous or secondary to intravitreal injections of anti-angiogenic agents retinal pigment epithelial tears in age-related macular degeneration

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International Journal of Ophthalmology(English edition) 2014年第4期7卷 681-685页

作者： Pia E.Leon Sandro Saviano Andrea Zanei Marco R.Pastore elvira Guaglione Alessandro Mangogna Daniele Tognetto University Eye Clinic of Trieste Ospedale Maggiore

·AIM:Toevaluatethevisualfunctionevolutionofretinal pigment epithelial(RPE) tears in patients with age-related macular degeneration(AMD) according to type of occurrence [spontaneous or secondary to anti-vascular endothelial growth factor(anti-VEGF) injection] and the topographic location of the tear after a two-year followup period.·METHODS: A total of 15 eyes of 14 patients with RPE tears in exudative AMD were analyzed retrospectively at the University Eye Clinic of Trieste. Inclusion criteria were: patient age of 50 or older with AMD and RPE tears both spontaneous occurring or post anti-VEGF treatment. Screening included: careful medical history,complete ophthalmological examination, fluorescein angiography(FA), indocyanine green angiography(ICG),autofluorescence and infrared imaging and optical coherence tomography(OCT). Patients were evaluated every month for visual acuity(VA), fundus examination and OCT. Other data reported were: presence of PED,number of injections before the tear, location of the lesion.·RESULTS:Meanfollow-up was24wk(SD±4wk). Atotal of 15 eyes were studied for RPE tear. In 6 cases(40%),the RPE tears occurred within two years of anti-VEGF injections the others occurred spontaneously. In 13cases(86.6%), the RPE tear was associated with pigment epithelial detachment(PED). In 7 cases(46.6%), the RPE tear occurred in the central area of the retina and involved the fovea. Two lesions were found in the parafoveal region, six in the extra-macular area. In all cases visual acuity decreased at the end of the follow-up period(P <0.01) independently of the type or the topographical location of the lesion.·CONCLUSION: RPE tear occurs in exudative AMD as a spontaneous complication or in relation to anti-VEGF injections. Visual acuity decreased significantly and gradually in the follow-up period in all cases. No correlation was found between visual loss and the type of onset or the topographic location of the tears.

关键词： retinal pigment epithelial age-related macular degeneration tears visual acuity anti-vascular endothelial growth factor treatment

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Kirill Bclorukov & elvira Skrylnikova 我们不是严肃的俄罗斯人

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尚舞 2014年第12期 18-21页

作者：禾页 Kiril elvira 北京舞燃情国标舞俱乐部

Kiril生于1990年,elvira生于1991年,他们是只有24、23岁的90后舞者,业余组拉丁舞决赛选手里最年轻的一对。可是如果有机会和elvira聊天,你会发现,这位女孩有着超乎年龄的成熟,在20岁出头的生命里,是他们经历了太多?还是天生悟性高?还是... 详细信息

Kiril生于1990年,elvira生于1991年,他们是只有24、23岁的90后舞者,业余组拉丁舞决赛选手里最年轻的一对。可是如果有机会和elvira聊天,你会发现,这位女孩有着超乎年龄的成熟,在20岁出头的生命里,是他们经历了太多?还是天生悟性高?还是遇到了指点他们的大师?开始与结束Kiril可以说是"舞二代",父母曾经是对体育舞蹈选手,他一两岁的时候就在父母开的舞蹈俱乐部里蹦跶,3岁就开始学习舞蹈,11岁的时候就开始和名师Tone Nyhagen学习了。Kirill自小已经习惯了舞蹈的存在。7岁那年,Kiril获得了俄罗斯锦标赛少儿组亚军,还在做选手的父母预见了Kiril的未来,为了能有更多时间培养孩子,停止了

关键词：拉丁舞 elvira Skrylnikova Kirill Bclorukov 恋人关系莫斯科

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Effect of genistein on acrosome reaction and zona pellucida binding independent of protein tyrosine kinase inhibition in bull

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Asian Journal of Andrology 2007年第5期9卷 650-658页

作者： Viviana A. Menzel elvira Hinsch Wolfgang Haigele Klaus-Dieter Hinsch Center of Dermatology and Andrology Justus Liebig University Giessen Giessen D-35392 Germany

Aim： To investigate if the phytoestrogen, genistein, affects essential functions of cryopreserved bovine spermatozoa. Methods： The effect of genistein upon motility was assessed by computer-assisted motion analysis. Hemizona assay was performed to detect the ability of spermatozoa binding to the zona pellucida. The inducibility of the acrosome reaction using progesterone and ZP3-6 peptide was analysed by fluorescein-conjugated Pisum sativum agglutinin （FITC-PSA）/Hoechst 33258 double staining. Capacitation after incubation with genistein was assessed by the chlortetracycline （CTC） assay. Immunoblots showed the pattern of protein tyrosine phosphorylation of cryopreserved bovine spermatozoa. Results： Immunodetection of tyrosine-phosphorylated proteins showed that genistein did not affect tyrosine phosphorylation in cryopreserved bovine spermatozoa. However, genistein significantly reduced the progesterone- and ZP3-6 peptide-mediated induction of the acrosome reaction and led to a dose-dependent inhibition of sperm-zona pellucida binding; while sperm motility and capacitation were not affected by this phytoestrogen, as indicated by computer-assisted sperm motion analysis and the CTC assay, respectively. Conclusion： Our results suggest that in cryopreserved bovine spermatozoa, genistein affects a protein tyrosine phosphorylation-independent signal transduction pathway that is involved in sperm capacitation, the acrosome reaction and sperm-zona pellucida binding.

关键词： genistein sperm motility acrosome reaction capacitation tyrosine phosphorylation cryopreservation zona pellucida

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Land Use and Land Management during the Past Century Determine Mangrove Dynamics in Northwestern Puerto Rico： the Case of the Maracayo Mangrove

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Journal of Environmental Science and Engineering(B) 2017年第12期6卷 593-623页

作者： Mónica Salazar-Ortiz elvira Cuevas Department of Environmental Sciences the University of Puerto Rico Río Piedras Campus San Juan Puerto Rico 00931 USA Department of Biology the University of Puerto Rico Río Piedras San Juan Puerto Rico 00931 USA CATEC (Center for Applied Tropical Ecology and Conservation) University of Puerto Rico Río Piedras Campus San Juan Puerto Rico 00931 USA

Political and economic decisions have determined throughout the history of Puerto Rico land use for agriculture, livestock and urban sprawl. Knowing this, this study is imperative to understand how these changes caused by the various uses and management affected adjoining wetlands. It is hypothesized that these changes affected the hydrology of the area, resulting in increased salinity, providing the right niche for the development of current mangrove. The resources used were aerial photographs, oral history, a report done in 1979 by the Department of Natural and Environmental Resources of the Government of Puerto Rico and analyses of salinity, pH and conductivity of soils in three different sites. The conclusion of this study was that the wetland underwent changes in ecosystem composition by ambitious elimination of sand dunes due to hydrological changes and marine effects. The oral history confirms the presence of springs in the past and present. Salinity intrusion was documented in those springs in the 1979 report due to land use change and elimination of sand dunes, changing the habitat, therefore allowing a mangrove community to be established. The continuity of ecophysiological and hydrogeological studies of the area will allow for a predictive understanding of how the mangrove wetland will continue developing.

关键词： GIS mangrove wetland land use dynamics.

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汉印时态词对比分析与教学

汉印时态词对比分析与教学

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作者： elvira SEPTEVANY （邓捷）南昌大学

学位级别：硕士

对于外国留学生来说,汉语时态词是一个常见的,也是相对来说比较难掌握的语法点。相关调查问卷的结果显示,印尼学生对时态词缺乏基本的认识,在使用过程当中,经常会出现这样或那样的错误。带着这个问题,笔者考察了汉印时态词的共同点和不... 详细信息

对于外国留学生来说,汉语时态词是一个常见的,也是相对来说比较难掌握的语法点。相关调查问卷的结果显示,印尼学生对时态词缺乏基本的认识,在使用过程当中,经常会出现这样或那样的错误。带着这个问题,笔者考察了汉印时态词的共同点和不同点,并通过调查问卷分析印尼学生学习汉语时态词时出现的偏误及原因,最后来探讨针对印尼学生行之有效的教学方法。第一章主要论述汉印时态词的共同点。本文写了汉印时态词“着与sedang”、“了与sudah”、“过与pernah”的共同点。汉语与印尼语时态词有一些相似的地方。例如:汉语的“了”与印尼语的“sudah”都可修饰动词表示一个动作的完成。汉语的“着”与印尼语的“sedang”都可修饰动词表示一个动作的持续。汉语的“过”与印尼语的“pernah”都可修饰动词表示一个动作曾经发生等等。第二章主要论述汉印时态词的不同点。通过表格形式列举汉语时态助词“着”、“了”、“过”和印尼语时态副词“sedang”、“sudah”、“pernah”的不同点。在汉语语法中,“着”、“了”、“过”被划分在时态助词的范畴,而在印尼语语法中,这几个词却被划分在时态副词的范畴。第三章主要论述汉印时态词差异的原因。第四章,通过调查问卷的形式分析印尼学生在习得汉语时态词时出现的偏误。被调查者都是南昌大学的印尼学生,人数为20人,调查问题为18个。印尼学生在学习汉语时态词出现了四种频率较高的偏误:误加、遗漏、误用、错位。第五章从教师和学生角度,分别论述了对印尼学生学习汉语时态词的教学建议。

关键词：汉印时态词对比分析偏误教学法

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