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Delay Times and Clinical Outcomes in Acute Myocardial Infarction: Comparison of Periods before and during the COVID-19 Pandemic—Myocardial Infarction and the Pandemic

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World Journal of Cardiovascular Diseases 2024年第6期14卷 392-400页

作者： Clarice Teixeira Silva Araújo Arnon Salviato Mameri Thúlio Carrera Guarçoni Venturini Marcus Tadeu Aguilar Constantino Matos Igor Morais Araujo lopes Luiz gustavo Ribeiro de Carvalho Murad Cleberson Duartes Ovani Guilherme Vassalo Morais Fernanda Venturini de Castro Danielle lopes Rocha Lucas Crespo de Barros Rodolfo Costa Sylvestre Luiz Fernando Machado Barbosa Roberto Ramos Barbosa Internal Medicine Universidade Federal do Esprito Santo (UFES) Vitria Brazil Hospital Santa Casa de Misericrdia de Vitria Vitria Brazil Hospital Santa Rita de Cssia Vitria Brazil Hospital Estadual Dr. Jayme Santos Neves Serra Brazil Grupo Kora Sade Vitria Brazil Hospital Estadual Infantil e Maternidade Alzir Bernardino Alves (HIMABA) Vila Velha Brazil

Introduction: At the beginning of the COVID-19 pandemic, a drop in the number of patients treated for cardiac emergencies raised concern about cardiovascular mortality in that period. An increase in care delay for patients with ST-segment elevation myocardial infarction (STEMI) may have affected clinical outcomes. Objectives: To analyze delay times and clinical outcomes of patients with STEMI undergoing primary percutaneous coronary intervention (PPCI), before and during the COVID-19 pandemic. Methods: Retrospective observational study that included patients with STEMI undergoing PPCI from December 2018 to July 2021. The COVID-19 pandemic cases were divided into two groups: pandemic I—from March to August 2020;and pandemic II—from September 2020 to July 2021. Patients were compared according to the period of hospitalization. Primary outcomes were delay times in assistance and clinical outcomes (acute kidney injury [AKI], post-procedural vascular complications and in-hospital mortality). Results: 108 patients were included, 39 (36.1%) in the pre-pandemic period, 13 (12.1%) in pandemic I and 56 (51.8%) in pandemic II. Time from onset of symptoms to arrival at the service and door-to-balloon time did not differ significantly among groups. Vascular complications were more frequent during the pandemic (I and II) than in the pre-pandemic period (2.5% pre-pandemic vs 15.4% pandemic vs 12.5% pandemic II;p = 0.03). AKI incidence was similar in all three periods. There was a non-significant increase in in-hospital mortality during the COVID-19 pandemic. Conclusion: In patients with STEMI, there was an increase in vascular complications and a trend toward increased mortality during the COVID-19 pandemic. Delay times to admission and reperfusion did not differ significantly between before and during the pandemic.

关键词： Myocardial Infarction Primary Percutaneous Coronary Intervention Coronary Reperfusion Pandemic COVID-19

Respiratory muscle training with electronic devices in the postoperative period of hepatectomy:A randomized study

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World Journal of Hepatology 2023年第5期15卷 688-698页

作者： Marcelo gustavo Pereira Aurea Maria Oliveira Silva Fernanda Diório Masi Galhardo Beatriz Dellamutta Miranda Almeida Railaine Lais lopes Ilka de Fatima Santana Ferreira Boin Hospital de Clínicas Universidade Estadual de CampinasCampinas 13076-4151São PauloBrazil Faculdade de Ciências Médicas Universidade Estadual de CampinasCampinas 13083-887São PauloBrazil Hospital de Clínicas da Unicamp Universidade Estadual de CampinasCampinas 13083-888São PauloBrazil

BACKGROUND Many studies have been developed with a focus on surgical techniques and drugs,but few that address the importance of rehabilitation in the pre and postoperative period,and the specific benefits for each surgical procedure or type of neoplasm,aiming to minimize respiratory complications in the postoperative *** To compare the strength of the respiratory muscles in the pre and postoperative periods of hepatectomy by laparotomy and to verify the incidence of postoperative pulmonary complications among the groups *** Prospective,randomized,clinical trial study that compared the inspiratory muscle training group(GTMI)with the control group(CG).After the collection of sociodemographic and clinical data,in both groups,preoperatively,on the first and fifth postoperative days,vital signs and pulmonary mechanics were evaluated and *** and bilirubin values were recorded for the albumin-bilirubin(ALBI)*** randomization and allocation of participants,those in the CG underwent conventional physical therapy and those in the GTMI underwent conventional physical therapy plus inspiratory muscle,in both groups for five postoperative *** Of 76 subjects met eligibility *** collection of 41 participants was completed:20 in the CG and 21 in the *** most frequent diagnosis was 41.5%with liver metastasis,followed by 26.8%with hepatocellular *** for respiratory complications in the GTMI,there was no *** the CG,there were three respiratory *** in the CG classified as ALBI score 3 presented,statistically,a higher energy value compared to patients classified as ALBI score 1 and 2(P=0.0187).Respiratory variables,measured preoperatively and on the first postoperative day,had a significant drop in both groups from the preoperative to the first postoperative day(P≤0.0001).When comparing the preoperative period and the fifth postoperative day between the GTMI and the CG,the maximal inspira

关键词： postoperative shorter fifth

Alkaline hydrolyzable nitrogen and properties that dictate its distribution in paddy soil profiles

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Pedosphere 2020年第3期30卷 326-335页

作者： Gerson Laerson DRESCHER Leandro Souza DA SILVA Qamar SARFARAZ gustavo DAL MOLIN Laura Brondani MARZARI Augusto Ferreira lopes Cesar CELLA Daniela Basso FACCO Rodrigo Knevitz HAMMERSCHMITT Department of Soil Science Federal University of Santa MariaSanta Maria 97105-900Brazil Federal University of Santa Maria Campus Cachoeira do SulCachoeira do Sul 96506-310Brazil

Nitrogen(N) is a key nutrient for rice production, and its bioavailability in paddy soils is strongly coupled to soil organic matter(SOM) cycling. A better understanding of potentially available N forms in soil, such as alkaline hydrolyzable N(AH-N), and their depth distribution will support the development of best management practices to improve the N use efficiency of rice while minimizing adverse environmental effects. Fifteen rice(Oryza sativa L.) fields from Southern Brazil were selected, and stratified soil samples were taken to a depth of 60 cm before crop establishment. Selected soil physical and chemical properties were analyzed to evaluate their relationships with AH-N contents in the soil profile. The AH-N contents below 20 cm varied extensively(increased,reduced, or constant) compared with that above 20 cm. Although clay and clay + silt contents were highly correlated to AH-N for some soils, the major property dictating AH-N distribution by depth was total N(TN), as the correlation between TN and AH-N was mainly by direct effect. The proportion of TN recovered as AH-N across sites and depths presented high amplitude, and thus AH-N was not a constant N pool across depths, indicating that AH-N can be affected by soil management practices even when TN showed no major changes. The distinct distribution of AH-N across soil sampling sites and depths indicates that depths greater than 20 cm should be considered when calibrating the AH-N index for N fertilizer recommendations for flooded rice in Southern Brazil.

关键词： fertilizer recommendation nitrogen availability nutrient management practices organo-mineral interaction Oryza sativa L. soil analysis soil organic matter

Biofloc technology (BFT): Adjusting the levels of digestible protein and digestible energy in diets of Nile tilapia juveniles raised in brackish water

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Aquaculture and Fisheries 2020年第1期5卷 42-51页

作者： Emerson Giuliani Durigon Rafael Lazzari Juliano Uczay Diogo Luis de Alcântara lopes Gabriela Tomas Jerônimo Tayna Sgnaulin Maurício gustavo Coelho Emerenciano Santa Catarina State University(UDESC) Animal Science Postgraduate Program(PPGZOO/UDESC)Chapecó88035Brazil Santa Catarina State University(UDESC) Nutrition Laboratory of Aquatic Organisms(LANOA/UDESC)Laguna 88035Brazil Santa Maria Federal University(UFSM) Animal Science and Biological Sciences DepartmentPalmeira Das MissõesPalmeira Das Missões 88035Brazil Santa Catarina Federal University(UFSC) Aquatic Organisms Health Laboratory(AQUOS)Aquaculture DepartmentFlorianópolis 88035Brazil

Several studies have been performed adjusting the levels of dietary digestible protein and digestible energy for tilapia,but none of them was performed in biofloc technology(BFT)system,especially in brackish(10)*** this sense,three levels of digestible protein(22,26 and 30%DP)and three levels of digestible energy(3000,3150 and 3300 kcal DE/kg)were evaluated on growth performance,body composition,hematological parameters and planktonic community in juveniles of Nile tilapia(***)raised under BFT conditions.A total of 540 tilapia fingerlings(GIFT strain with 1.25±0.15 g initial weight)were reared during 42 days in thirty-six plastic tanks(75 L),fed three times a *** interaction was detected in the parameters *** fish fed with feed containing 26%and 30%of DP obtained higher final weight,specific growth rate and condition factor as compared to those fed with 22%of DP(P<0.05).Body protein on tilapia carcass increased proportionally according to dietary *** higher dietary energy level promoted a higher body lipid *** to hematological parameters fish from all treatments presented a satisfactory immunological *** monitoring of planktonic community indicated a variation over time,specially on the number of dinoflagellates,rotifers and *** results indicated that diets containing 26%of DP and 3150 kcal/kg of DE for Nile tilapia juveniles promoted suitable growth performance and health conditions when reared in biofloc brackish water,and enabled savings in regards to dietary protein once the energy levels were adjusted.

关键词： Hematology Microbial floc Nursery Nutrition

Isolated Autoimmune Orchitis Due to IgG4 Hypersecretion Presenting as Tumor-Like Mass: Case Report and Review of Literature

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Open Journal of Urology 2022年第1期12卷 51-56页

作者： Francisco Marcos da Silva Barroso Flavio Antunes de Sousa Paloma Menezes de Souza gustavo lopes de Castro Katia Ramos Moreira Leite Monique Freire Santana Roger Arthur da Cunha Alves Gabriela Ayumi Owada Borges Juan Eduardo Rios Rodriguez Urology Service Getúlio Vargas University Hospital (HUGV) Manaus Amazonas Brazil General Surgery Service Santa Casa de Ribeir&#227 o Preto Ribeir&#227 o Preto Brazil Sã o Paulo University (USP) Ribeir&#227 o Preto Brazil Faculty of Medicine Federal University of Amazonas (UFAM) Manaus Amazonas Brazil Pathology Department Sírio-Libanes Hospital S&#227 o Paulo Brazil Faculty of Medicine S&#227 o Paulo University (USP) S&#227 o Paulo Brazil Patholgy Service Getúlio Vargas University Hospital (HUGV) Manaus Amazonas Brazil Dr. Heitor Vieira Dourado Tropical Medicine Foundation Manaus Amazonas Brazil Teaching and Research Department Oncology Center Control Foundation (FCECON) Manaus Amazonas Brazil Urology Service Hospital Pronto-Socorro 28 de Agosto Manaus Amazonas Brazil General Surgery Service Getúlio Vargas University Hospital (HUGV) Manaus Amazonas Brazil

Background: IgG4-related disease is a rare autoimmune condition that presents with lymphoplasmacytic infiltrate and fibrosis in the organ affected. Isolated testicle involvement is uncommon and there are only a few cases reported in the literature. Case Presentation: We report a case of isolated chronic orchitis due to IgG4 hypersecretion in a 61-year-old patient that evolved with asymptomatic tumor-like mass growth and was treated with left orchiectomy. Histopathological study revealed orchitis related to IgG4 hypersecretion disease. Conclusion: IgG4-related disease can be manifested as a multi or single-organ disorder. Most diagnoses are made after surgery with histopathological analysis. Most of the cases in literature stand out the difficulty in diagnosis and necessity of high suspicion due to this condition’s similarity with neoplasm presentation.

关键词： Orchitis IgG4-Related Disease Autoimmune Testicle Inflammatory

Adenosquamous Carcinoma Affecting the Maxilla: A Case Report and Review

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Journal of Cancer Therapy 2017年第3期8卷 286-295页

作者： Marcos Martins Curi Marcelo Ferraz de Oliveira Anthony Froy Benites Condezo Heliton gustavo Lima Andréia Aparecida da Silva Carlos César DeAntoni Camila lopes Cardoso Department of Oral and Maxillofacial Surgery Hospital Santa Catarina S&atilde o Paulo Brazil Department of Implantology P-I Branemark Institute S&atilde o Paulo Brazil Department of Oral Surgery Universidade do Sagrado Cora&ccedil ã o S&atilde o Paulo Brazil Department on Oral Pathology University of S&ccedil o Paulo S&ccedil o Paulo Brazil

Adenosquamous carcinoma of the head and neck (ASC) is a rare and aggressive variant of squamous cell carcinoma, a locally aggressive malignancy characterized by the presence of two distinct components: a squamous cell carcinoma and an adenocarcinoma. The purpose of this study was to report an additional rare case of adenosquamous carcinoma affecting the maxilla, with clinical microscopic features and a complex mid-facial rehabilitation.

关键词： Squamous Cell Carcinoma Adenosquamous Carcinoma Implant Supported Prosthesis Maxillofacial Rehabilitation

Use of the American Society of Anesthesiologists Classification as an Additional Planning Tool for Renal Cell Carcinoma Assessment

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Journal of Cancer Therapy 2013年第9期4卷 7-14页

作者： Daniel Beltrame Ferreira Stenio de Cassio Zequi Walter Henriques da Costa Diego Abreu Clavijo Ricardo Decia Deusdedit Cortez Neto Renato Rosa de Oliveira gustavo Cardoso Guimaraes Ademar lopes Urology Division Department of Pelvic SurgeryA.C.Camargo Cancer CenterSao PauloBrazil Department of Urology Pasteur HospitalMontevideoUruguay

Objective: To determine the prognostic value of the American Society of Anesthesiologists (ASA) classification and of the main clinical pathologic variables in renal cell carcinoma (RCC) patients who underwent surgical treatment. Methods: In this international collaborative study, 376 RCC patients who underwent partial nephrectomy (PN) or radical nephrectomy (RN) during the period 1989-2009 were assessed. The pathological data were reviewed by a single pathologist, and all of the surgically treated patients had been previously evaluated by a team of anesthesiologists and classified as ASA 1, ASA 2, or ASA 3. Results: In total, 318 patients were included in the study, with a mean followup of 48 months. Incidental tumors represented 47% of the cases, while 11.6% presented with metastases at diagnosis. Among the patients assessed, 38 (11.9%) were classified as ASA 1, 213 (67%) as ASA 2, and 67 (21.1%) as ASA 3. An association between the ASA classification and the main clinicopathological variables of RCC was observed. The univariate analysis for overall survival (OS) revealed significant differences in the survival curves according to the ASA classification (p < 0.001). High-grade neoplasms, the presence of metastasis at diagnosis, clinical stage III/IV, and incidental tumors remained as independent predictors of survival. Moreover, the multivariate analysis revealed a negative impact of the ASA classification on OS (p = 0.001). Conclusions: The present study demonstrated a correlation between the ASA classification and the main prognostic factors of RCC and its impact on survival rates. ASA 3 patients had more aggressive tumors, increased risk of perioperative complications, and worse outcomes compared with ASA1 or ASA 2. Thus, the ASA classification may be considered an additional tool for assessing and planning the treatment of RCC patients.

关键词： Comorbidity Renal Cell Carcinoma ASA Prognosis Oncology

Performance of the Multiprofessional Team in Cytoreductive Surgeries with Intraperitoneal Hyperthermic Chemotherapy:Experience Reporting

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Journal of Pharmacy and Pharmacology 2018年第11期6卷 965-969页

作者： Cecília da Silva Angelo(RN) Ademar lopes(PhD) Catharina Ferreira de Meira Pachioni(MSc) Eduardo Henrique Giroud Joaquim(MSc) Samuel Aguiar Junior(PhD) gustavo Cardoso Guimaraes(PhD) Glauco Baiocchi Neto(PhD) Felipe JoséFernandez Coimbra(PhD) Isabel Miranda Bonfim(MSc) Rita de Cassia Burgos de Oliveira(PhD) Tailine Ligia Tadini(RN) A.C.Camargo Cancer Center Sao Paulo04002-010Brazil

Purpose:This study aims at reporting the experience of a cancer hospital’s multiprofessional team with surgery patients in performing cytoreductive surgeries associated with hyperthermic intraperitoneal ***:It is a reporting about the experience of the multiprofessional team at AC Camargo Cancer Center’s surgery center,which operates in cytoreductive surgeries with hyperthermic intraperitoneal chemotherapy,thus guaranteeing the surgery patient’s ***:No safety report for the surgery patient subjected to intraperitoneal hypothermic chemotherapy was found in the ***,the surgery center’s multiprofessional team’s practice was based on standards for manipulating chemotherapeutic agents and for safely administering medication.A checklist was elaborated for cytoreductive surgeries with hyperthermic intraperitoneal chemotherapy based on the surgery patient safety protocol and the institution’s multiprofessional team’s ***:From the multiprofessional team’s experiences in cytoreductive surgeries with hyperthermic intraperitoneal chemotherapy,the importance of elaborating a checklist to promote the quality of assistance and guarantee patient safety during the entire intraoperative phase became evident.

关键词： Patient safety chemotherapy for cancer by regional perfusion checklist

Hyporeninemic hypoaldosteronism and diabetes mellitus:Pathophysiology assumptions,clinical aspects and implications for management

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World Journal of Diabetes 2016年第5期7卷 101-111页

作者： Andre gustavo P Sousa Joao Victor de Sousa Cabral William Batah El-Feghaly Luísa Silva de Sousa Adriana Bezerra Nunes Department of Clinical Medicine Federal University of Rio Grande do Norte Onofre lopes University Hospital Federal University of Rio Grande do Norte

Patients with diabetes mellitus(DM) frequently develop electrolyte disorders,including *** most important causal factor of chronic hyperkalemia in patients with diabetes is the syndrome of hyporeninemic hypoaldosteronism(HH),but other conditions may also ***,as hyperkalemia is related to the blockage of the renin-angiotensin-aldosterone system(RAAS) and HH is most common among patients with mild to moderate renal insufficiency due to diabetic nephropathy(DN),the proper evaluation and management of these patients is quite *** its obvious relationship with diabetic nephropathy,HH is also related to other microvascular complications,such as DN,particularly the autonomic *** confirm the diagnosis,plasma aldosterone concentration and the levels of renin and cortisol are measured when the RAAS is *** addition,synthetic mineralocorticoid and/or diuretics are used for the treatment of this ***,few studies on the implications of HH in the treatment of patients with DM have been conducted in recent years,and therefore little,if any,progress has been *** comprehensive review highlights the findings regarding the epidemiology,diagnosis,and management recommendations for HH in patients with DM to clarify the diagnosis of this clinical condition,which is often neglected,and to assist in the improvement of patient care.

关键词： Hyporeninemic Diabetes Hyperkalemia Renal tubular acidosis Hypoaldosteronism