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Early-diverging fungal phyla:taxonomy,species concept,ecology,distribution,anthropogenic impact,and novel phylogenetic proposals

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Fungal Diversity 2021年第4期109卷 59-98页

作者： Kerstin Voigt Timothy Y.James Paul M.Kirk andréL.C.M.de A.Santiago Bruce Waldman Gareth W.Griffith Minjie Fu Renate Radek Jürgen F.H.Strassert Christian Wurzbacher gustavo Henrique Jerônimo David R.Simmons Kensuke Seto Eleni Gentekaki Vedprakash G.Hurdeal Kevin D.Hyde Thuong T.T.Nguyen Hyang Burm Lee Jena Microbial Resource Collection Leibniz Institute for Natural Product Research and Infection BiologyAdolf-Reichwein-Straße 2307745 JenaGermany Institute of Microbiology Faculty of Biological SciencesFriedrich Schiller University JenaNeugasse 2507743 JenaGermany Department of Ecology and Evolutionary Biology University of MichiganAnn ArborMI 48109USA Biodiversity Informatics and Spatial Analysis Jodrell LaboratoryRoyal Botanic Gardens KewSurrey TW93DSUK Department of Mycology Federal University of PernambucoAv.Da Engenharias/nRecifePE 50740-4600Brazil School of Biological Sciences Seoul National UniversitySeoul 08826South Korea Department of Integrative Biology Oklahoma State UniversityStillwaterOK 74078USA Institute of Biological Environmentaland Rural Sciences(IBERS)Aberystwyth UniversityAberystwyth SY233DDWalesUK Institute of Biology/Zoology Evolutionary BiologyFreie Universität Berlin14195 BerlinGermany Leibniz Institute of Freshwater Ecology and Inland Fisheries Ecosystem Research12587 BerlinGermany Department of Civil Geo and Environmental EngineeringTechnical University of MunichGarchingGermany School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand Environmental Microbiology Lab Department of Agricultural Biological ChemistryCollege of Agriculture&Life SciencesChonnam National UniversityGwangju 61186South Korea

The increasing number of new fungal species described from all over the world along with the use of genetics to define taxa,has dramatically changed the classification system of early-diverging fungi over the past several *** number of phyla established for non-Dikarya fungi has increased from 2 to ***,to date,both the classification and phylogeny of the basal fungi are still *** this article,we review the recent taxonomy of the basal fungi and re-evaluate the relationships among early-diverging lineages of fungal *** also provide information on the ecology and distribu-tion in Mucoromycota and highlight the impact of chytrids on amphibian *** concepts in Chytridiomycota,Aphelidiomycota,Rozellomycota,Neocallimastigomycota are discussed in this *** preserve the current application of the genus Nephridiophaga(Chytridiomycota:Nephridiophagales),a new type species,Nephridiophaga blattellae,is proposed.

关键词： Early-diverging fungi Evolution Nuclear large subunit(LSU/28S) Nuclear small subunit(SSU/18S) Molecular phylogeny

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Joint Multi-modal Parcellation of the Human Striatum:Functions and Clinical Relevance

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Neuroscience Bulletin 2020年第10期36卷 1123-1136页

作者： Xiaojin Liu simon B.Eickhoff Felix Hoffstaedter Sarah Genon Svenja Caspers Kathrin Reetz Imis Dogan Claudia R.Eickhoff Ji Chen Julian Caspers Niels Reuter Christian Mathys andre Aleman Renaud Jardri Valentin Riedl Iris E.Sommer Kaustubh R.Patil Institute of Neuroscience and Medicine(INM-7 Brain and Behaviour)Research Centre JiilichJiilichGermany Institute of Systems Neuroscience Heinrich Heine University DusseldorfDusseldorfGermany Institute of Neuroscience and Medicine(INM-1) Research Centre Jiilich52428 JiilichGermany Institute for Anatomy I Medical FacultyHeinrich Heine University Dusseldorf40225 DusseldorfGermany Jiilich Aachen Research Alliance-BRAIN(JARA)Institute of Molecular Neuroscience and Neuroimaging Forschungszentrum JiilichRheinisch Westfallische Technische Hochschule(RWTH)Aachen University52074 AachenGermany Department of Neurology Rheinisch Westfallische Technische Hochschule(RWTH)Aachen University52074 AachenGermany Institute of Clinical Neuroscience and Medical Psychology Medical FacultyUniversity of Dusseldorf40225 DusseldorfGermany Department of Diagnostic and Interventional Radiology Medical FacultyUniversity of Dusseldorf40225 DusseldorfGermany Institute of Radiology and Neuroradiology Evangelisches KrankenhausUniversity of Oldenburg26129 OldenburgGermany Department of Neuroscience University Medical Center GroningenUniversity of Groningen9713 AV GroningenThe Netherlands SCALab(CNRS UMR9193)&CHU de LiUe Hopital FontanPole de Psychiatrie(CURE)Universite de Lille59037 LilleFrance Departments of Neuroradiology Nuclear Medicine and Neuroimaging CenterTechnische Universitat Miinchen80333 MunichGermany

The human striatum is essential for both lowand high-level functions and has been implicated in the pathophysiology of various prevalent disorders,including Parkinson's disease(PD)and schizophrenia(SCZ).It is known to consist of structurally and functionally divergent ***,previous parcellations are based on a single neuroimaging modality,leaving the extent of the multi-modal organization of the striatum ***,we investigated the organization of the striatum across three modalities—resting-state functional connectivity,probabilistic diffusion tractography,and structural covariance—to provide a holistic convergent view of its structure and *** found convergent clusters in the dorsal,dorsolateral,rostral,ventral,and caudal *** characterization revealed the anterior striatum to be mainly associated with cognitive and emotional functions,while the caudal striatum was related to action ***,significant structural atrophy in the rostral and ventral striatum was common to both PD and SCZ,but atrophy in the dorsolateral striatum was specifically attributable to *** study revealed a cross-modal convergent organization of the striatum,representing a fundamental topographical model that can be useful for investigating structural and functional variability in aging and in clinical conditions.

关键词： Striatum Multi-modal Connectivity-based parcellation Convergent clusters Voxel-based morphometry Parkinson's disease Schizophrenia

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钻孔电磁波法在匈牙利铝土矿的初步应用

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物探与化探 1990年第6期14卷 437-443页

作者：易永森周鹤鸣 Lszl Szabadvry Ern Kirly andrs simon 中国地质勘查技术院物化探研究所爱维罗兰地球物理研究所

1987年10月27日—11月11日中匈地球物理工程者在匈牙利一号铝土矿区的13个钻孔中，使用中国地质勘查技术院物化探研究所研制的JWQ—3型单、双孔电磁波仪进行了试验。铝土矿的围岩为白云岩（石灰岩），矿与围岩的高频电性有明显的差异。... 详细信息

1987年10月27日—11月11日中匈地球物理工程者在匈牙利一号铝土矿区的13个钻孔中，使用中国地质勘查技术院物化探研究所研制的JWQ—3型单、双孔电磁波仪进行了试验。铝土矿的围岩为白云岩（石灰岩），矿与围岩的高频电性有明显的差异。通过初步应用，本方法可在间距为20—30m的铝土矿内的钻孔间探明白云岩体的存在；或在间距为40—60m的白云岩钻孔之间发现较大的铝土矿盲矿体。

关键词：钻孔电磁波法铝土矿找矿

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Monitoring and Environmental Assessment of Seawater in West Central Africa: Case of the Kribi Industrial and Urban Port Complex in Cameroon, Guinea Gulf

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Journal of Geoscience and Environment Protection 2021年第6期9卷 167-183页

作者： Mioumnde Arthur Paterne Kusi Micheline Michelle-Alexia Ngum Kag simon Pierre Kue Petou Rokis Malquaire Mumbfu Ernestine Mimba Botny-Capel Anne-Eunice Dissombo Edimo andré Noel Masso Kody Christelle Zebaze Jiofack Kevine Bessong Moise Institute of Geological and Mining Research Yaoundé Cameroon Key Laboratory of Deep Oil and Gas (China University of Petroleum (East China)) Qingdao China Department of Earth Sciences University of Yaoundé I Yaoundé Cameroon National Institute of Cartography Yaoundé Cameroon Postgraduate School of Sciences Technologies & Geosciences University of Yaoundé I Yaoundé Cameroon Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes Hohai University Nanjing China Department of Environmental and Natural Resources Protection Law Ocean University of China Qingdao China

This study is the first of a series of a project on the development and implementation of environmental protection policies, before, during and after the construction of the Kribi Industrial and Urban Port Complex (KIPC). The results will equip the State and scientific structures concerned with the protection of people, water resources and the environment as a whole. This includes reference data on the state of marine pollution in the region dating from the end of realization of the first phase of KIPC known as Kribi Deep-Water Harbor (KDWH). Accordingly, the aim of this work is to assess the current state of KIPC and its surrounding by quantifying the preliminary parameters of suspended matter (SM);to analyze the physical and chemical parameters, chemical pollution indicators for anions and major cations and organic pollution indicators of four water samples taken from four different sites in the project area by filtration and weighing, pH meter, turbid meter, titration, colorimetry and titrimetric methods. The analysis of these samples and these parameters provides results

关键词： Kribi Industrial Port Complex Seawater Monitoring and Environmental Assessment

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Personalized medicine:Clinical oncology on molecular view of treatment

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World Journal of Clinical Oncology 2024年第8期15卷 992-1001页

作者： Rafick Costa Dos Santos Da Silva Nathalia de andrade simon andréAlves Dos Santos Gabriel De Melo Olegário Jayne Ferreira Da Silva Naide Oliveira Sousa Manuel Alvarez Troncoso Corbacho Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória Da Conquista 45029-094BahiaBrazil

Cancer,the second leading global cause of death,impacts both physically and *** treatments such as surgeries,chemotherapy,and radiotherapy have adverse effects,driving the need for more precise *** medicine enables more targeted *** mapping,alongside other molecular biology approaches,identifies specific genes,contributing to accurate *** review addresses,in clinical use,a molecular perspective on *** like alpha-fetoprotein,beta-human chorionic gonadotropin,5-hydroxyindoleacetic acid,programmed death-1,and cytotoxic T lymphocyte-associated protein 4 are explored,providing valuable ***,with an emphasis on artificial intelligence,revolutionizes the analysis of biological data,offering more accurate *** like liquid biopsy are emphasized for early *** medicine guides therapeutic strategies based on the molecular characteristics of the tumor,as evidenced in the molecular subtypes of breast *** allow personalized treatments,highlighting the role of trastuzumab and endocrine *** the benefits,challenges persist,including high costs,tumor heterogeneity,and ethical *** obstacles requires collaboration,ensuring that advances in molecular biology translate into accessible benefits for all.

关键词： Oncology Neoplasia Molecular biology Personalized medicine Molecular Markers Cancer

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Designing Artemisinins with Antimalarial Potential, Combining Molecular Electrostatic Potential, Ligand-Heme Interaction and Multivariate Models

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Computational Chemistry 2023年第1期11卷 1-23页

作者： Josué de Jesus Oliveira Araújo Ricardo Morais de Miranda Jeferson Stiver Oliveira de Castro Antonio Florêncio de Figueiredo Ana Cecília Barbosa Pinheiro Sílvia simone dos Santos Morais Marcos Antonio Barros dos Santos andréia de Lourdes Ribeiro Pinheiro andréia de Lourdes Ribeiro Pinheiro Fábio dos Santos Gil Heriberto Rodrigues Bitencourt gustavo Nery Ramos Alves José Ciríaco Pinheiro Laboratório de Química Teórica e Computacional Universidade Federal do Pará Belém PA Brasil Instituto Federal de Educaç ã o Ciência e Tecnologia do Pará Belém PA Brasil Universidade do Estado do Amapá Macapá AP Brasil Fundaç ã o Santa Casa de Misericórdia do Pará Belém PA Brasil Universidade do Estado do Pará Barcarena PA Brasil Departamento de Biologia Universidade do Estado do Maranh&atilde o S&atilde o Luís MA Brasil Laboratório de Síntese Organica Universidade Federal do Pará Belém PA Brasil

Artemisinins tested against W-2 strains of malaria falciparum are investigated with molecular electrostatic potential (MEP), in an attempt to identify key features of the compounds that are necessary for their activities, as well as to investigate likely interactions with the receptor in a biological process and to use that information to propose new molecules. In order to discover the best geometry involving the ligand-receptor complexes (heme) studied and help in the proposition of the new derivatives, molecular simulations of interactions between the most negative charged region around the peroxide and heme locates (the ones around the Fe2+ ion) were carried out. In addition, PCA (principal components analysis), HCA (hierarchical cluster analysis), SDA (stepwise discriminant analysis), and KNN (K-nearest neighbor) multivariate models were employed to investigate which descriptors are responsible for the classification between the higher and lower antimalarial activity of the compounds, and also this information was used to propose new potentially active molecules. The information accumulated in studies of MEP, molecular docking, and multivariate analysis supported the proposal of new structures with potential antimalarial activities. The multivariate models constructed were applied to the new structures and indicated numbers 19 and 20 as the most prominent for syntheses and biological assays.

关键词： Artemisinins Antimalarial Potential Molecular Electrostatic Potential Ligand-Heme Interaction Multivariate Models

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Common interacting genetic variation shapes susceptibility to type 1 diabetes in a Colombian Caribbean community:In search of shared genetic markers

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Genes & Diseases 2024年第4期11卷 106-108页

作者： Gloria Garavito-De Egea Alex Dominguez-Vargas Jorg e l.Velez gustavo Aroca Luis Fagng Elkin Navarro-Quiroz Zilac Espitaleta Kenny Del Toro-Camargo Leticia Martinez-Ariza Tatiana Gonzalez-Vargas Susana Garcia Mauricio Arcos-Burgos Eduardo Egea Universidad del Norte Division Ciencias de la SaludBarranquillaColombia Universidad simon Bolivar Facultad de Ciencias de la SaludBarranquillaColombia Clinica de la Costa Grupo de Investigacion en NefrologiaBarranquillaColombia Universidad de Antioquia Grupo de Investigacion en Psiquiatria(GIPSI)Departamento de PsiquiatriaInstituto de Investigaciones MedicasFacultad de MedicinaMedellinColombia

Genome-wide association studies(GWASs)have identified hundreds of loci across the human genome conferring susceptibility to autoimmune diseases(AIDs),some of which are shared between more than two ***,this univariate ... 详细信息

关键词： susceptibility diseases diabetes

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Active stabilization of terahertz waveforms radiated from a two-color air plasma

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Photonics Research 2022年第1期10卷 96-103页

作者： YONGHAO MI KYLE JOHNSTON VALENTINA SHUMAKOVA SφREN H.MφLLER KAMALESH JANA CHUNMEI ZHANG andré STAUDTE SHAWN SEDERBERG PAUL B.CORKUM Joint Attosecond Science Laboratory University of Ottawa and National Research Council CanadaOntario K1N 6X1Canada School of Engineering Science Simon Fraser UniversityBurnabyBritish Columbia V5A 1S6Canada

Intense laser fields focused into ambient air can be used to generate high-bandwidth current densities in the form of plasma channels and *** with bichromatic fields enables us to adjust the amplitude and sign of these currents using the relative phase between the two light ***-color filamentation in gas targets provides a route to scaling the energy of terahertz pulses to microjoule levels by driving the plasma channel with a high-energy laser ***,the structure of plasma channels is highly susceptible to drifts in both the relative phase and other laser parameters,making control over the waveform of the radiated terahertz fields *** establish a clear link between the phase dependence of plasma currents and terahertz radiation by comparing in situ detection of current densities and far-field detection of terahertz electric *** show that the current measurement can be used as a feedback parameter for stabilizing the terahertz *** approach provides a route to energetic terahertz pulses with exceptional waveform stability.

关键词： stabilization terahertz Active

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古斯塔夫·杜达梅尔:天生“指挥狂”

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疯狂英语（新悦读） 2016年第3期 18-21页

作者： Bob simon Betty

古斯塔夫·杜达梅尔就像一名真正的魔法师!他有一头堆满谱号与音符的黑卷发,他手中的指挥棒简直就像魔法棒,让人沉醉在他的音乐魔法世界里不可自拔.目前,这位来自委内瑞拉的指挥家同时受聘于瑞典哥德堡交响乐团与美国洛杉矶爱乐团,成为... 详细信息

古斯塔夫·杜达梅尔就像一名真正的魔法师!他有一头堆满谱号与音符的黑卷发,他手中的指挥棒简直就像魔法棒,让人沉醉在他的音乐魔法世界里不可自拔.目前,这位来自委内瑞拉的指挥家同时受聘于瑞典哥德堡交响乐团与美国洛杉矶爱乐团,成为了指挥界最耀眼的明星.和所有誉满天下的人一样,古斯塔夫的成功从来不是一蹴而就.他四岁开始学习相关乐理知识,练过小提琴,学过作曲,之后师从委内瑞拉著名指挥家阿布莱乌学习指挥.2004年国际马勒交响乐指挥大赛的冠军奖杯让全世界认识了这个指挥时洋溢着火一样激情的小伙子,随之而来的“杜达梅尔热”烧遍了全世界.

关键词：古斯塔夫指挥棒天生交响乐团委内瑞拉魔法师乐理知识指挥家

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丹麦NOMA食品实验室

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设计家 2012年第2期 84-89页

作者： KIm Herforth Nielsen Kasper Guldager J rgensen andr van leth lila Held Morten Norman Lund Lars-Erik Eriksson Pedram Seddighzadeh Matthew Scarlett BjHrk Christensen Kyle Baumgardner Elliot Mistur Tore Banke simon McKenzie Jacob Hilmer Pauline Pan GXN

由3XN负责的NOMA食品实验室室内设计项目巧妙地将烹饪与建筑融为一体．并为北欧菜肴打造出最佳的效果呈现舞台。

关键词： NOMA 实验室食品丹麦设计项目

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