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Time-sensitive prediction of NO_(2) concentration in China using an ensemble machine learning model from multi-source data

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Journal of Environmental Sciences 2024年第3期137卷 30-40页

作者： Chenliang Tao Man Jia guoqiang wang Yuqiang Zhang Qingzhu Zhang Xianfeng wang Qiao wang Wenxing wang Big Data Research Center for Ecology and Environment Environment Research InstituteShandong UniversityQingdao 266237China Shandong Provincial Eco-environment Monitoring Center Jinan 250101China

Nitrogen dioxide(NO_(2))poses a critical potential risk to environmental quality and public health.A reliable machine learning(ML)forecasting framework will be useful to provide valuable information to support government *** on the data from1609 air quality monitors across China from 2014-2020,this study designed an ensemble ML model by integrating multiple types of spatial-temporal variables and three sub-models for time-sensitive prediction over a wide *** ensemble ML model incorporates a residual connection to the gated recurrent unit(GRU)network and adopts the advantage of Transformer,extreme gradient boosting(XGBoost)and GRU with residual connection network,resulting in a 4.1%±1.0%lower root mean square error over XGBoost for the test *** ensemble model shows great prediction performance,with coefficient of determination of 0.91,0.86,and 0.77 for 1-hr,3-hr,and 24-hr averages for the test results,*** particular,this model has achieved excellent performance with low spatial uncertainty in Central,East,and North China,the major site-dense *** the interpretability analysis based on the Shapley value for different temporal resolutions,we found that the contribution of atmospheric chemical processes is more important for hourly predictions compared with the daily scale predictions,while the impact of meteorological conditions would be ever-prominent for the *** with existing models for different spatiotemporal scales,the present model can be implemented at any air quality monitoring station across China to facilitate achieving rapid and dependable forecast of NO_(2),which will help developing effective control policies.

关键词： Air quality prediction Deep learning Ensemble method Nitrogen dioxide Spatiotemporal covariates

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A method to determine the bonded-particle model parameters for simulation of ores

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Particuology 2024年第3期86卷 24-38页

作者： Shuwei Wu guoqiang wang Longfei Fan Wei Guan Jianbo Guo Zhengbin Liu Yukuan wang School of Mechanical and Aerospace Engineering Jilin UniversityChangchun130025China

The bonded-particle model(BPM)is commonly used in the numerical analysis of ore *** improve the accuracy of simulating the mechanical process of ore process of ore crushing in a crusher,the parameters of the BPM for the ore must be *** this study,a calibration method was proposed for the scientific determination of the parameters of the BPM for ore undergoing uniaxial ***,physical tests and simulations were conducted to determine the mechanical response(uniaxial compressive strength and macroscopic stiffness)of ore during uniaxial ***,the sensitivity of the mechanical response to the values of microscopic parameters was tested using a Plackett-Burman ***,the microscopic parameters with the greatest impact on the response were identified,and the range of parameters that met the target response was determined using a steepest ascent design;Second,a second-order model of the mechanical response was established using the sensitive parameters by combining a Box-Behnken design with response surface methodology to obtain the optimal BPM *** tests showed that the normal stiffness per unit area,critical shear stress,and bonded disk radius had significant effects on the uniaxial compressive strength(UCS)and macroscopic stiffness(MS).To verify the validity of the proposed calibration method,laboratory tests were *** consistency of the simulation results with experimental results indicated that response surface methodology with the Plackett-Burman design,steepest ascent design,and Box-Behnken design can be an effective method for calibrating the BPM of ores.

关键词： Bonded-particle model Discrete element method Calibration method Design of experiment Uniaxial compression test

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Statistical study of magnetic holes in the upstream region of Mercury’s bow shock

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Earth and Planetary Physics 2024年第2期8卷 326-337页

作者： guoqiang wang SuDong Xiao MingYu Wu YuanQiang Chen TieLong Zhang Institute of Space Science and Applied Technology Harbin Institute of TechnologyShenzhen 518055China Shenzhen Key Laboratory of Numerical Prediction for Space Storm Harbin Institute of TechnologyShenzhen 518055China Mengcheng National Geophysical Observatory University of Science and Technology of ChinaHefei 230026China Chinese Academy of Sciences Center for Excellence in Comparative Planetology Hefei 230026China Space Research Institute Austrian Academy of SciencesGrazAustria

Magnetic holes are magnetic depression structures that exist widely in many plasma *** magnetic holes with durations of>1 s in the solar wind at Mercury’s orbit have drawn much attention,but the properties of the magnetic holes with shorter durations are still ***,we investigate the magnetic holes with durations of 0.1-100 s in the upstream region of Mercury’s bow shock based on observations by the MESSENGER(MErcury Surface,Space ENvironment,GEochemistry,and Ranging)*** can be divided into two groups according to the distribution of their duration:small-duration magnetic holes(SDMHs,0.6 s).The duration of each group approximately obeys a log-normal distribution with a median of~0.25 s and 3 s,*** 1.7%(32.6%)of the SDMHs(LDMHs)reduce the magnetic field strength by more than 50%.For both groups,some structures have a linear or quasi-linear polarization,whereas others have an elliptical *** magnetic hole events in both groups tend to have a higher rate of occurrence when the interplanetary magnetic field strength is *** occurrence rates are also affected by Mercury’s foreshock,which can increase(decrease)the occurrence rate of the SDMHs(LDMHs).This finding suggests that Mercury’s foreshock might be one source of the SDMHs and that the foreshock can destroy some *** observations suggest that a new group of magnetic holes with durations of<0.6 s exist in the upstream region of Mercury’s bow shock.

关键词： magnetic hole solar wind Mercury foreshock

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Rice stem lodging properties and bending modeling under the influence of circadian temperature difference

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International Journal of Agricultural and Biological Engineering 2024年第3期17卷 21-32页

作者： Bangzhui wang Zhong Tang Liyun Lao guoqiang wang Tiantian Jing Yao Yu School of Agricultural Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina School of Water Energy and EnvironmentCranfield UniversityMK430ALUK Department of Agricultural Engineering Jiangsu Agriculture&Animal Husbandry Science and Technology Vocational CollegeTaizhou 225300JiangsuChina

Under diurnal temperature stress,the vascular bundle content of mature rice stems will change which will cause a change in the modulus of ***,the rice stems will collapse with the reduction in bending resistance because of the change in the modulus of *** order to reveal the distribution of vascular bundle gradients in rice stems under different climatic temperatures and explore the locations where stems are prone to bending and the form of stem damage,this study established a model of stem stiffness under free loading based on observing microstructure of the *** lodging characteristics of rice stems was explored seldom in different environmental temperatures from a micro structure of rice ***,the statistical analysis and t-tests were carried out on stems 1 to 4 in combination for cantilever bending tests at room temperature on stem internodes 3,versus three-point bending tests at-10℃ to 65℃ temperature *** showed that the bending resistance of the stem can be well predicted by using the vascular bundle distribution regression model and the variable stiffness mechanical *** bending resistance of No.3 stem was established by using the results obtained from the three-point bending test in a temperature range between 10℃-65℃.The correction coefficient TF of stem bending resistance under temperature difference induced stress was established based on the Gauss regression *** analysis showed that the bending resistance of No.3 stem was relatively large in a temperature range of 16℃-34℃.This study elucidated the variations of the mechanical properties of rice stems under temperature difference induced stress and provided a theoretical foundation for understanding the lodging characteristics of rice during mechanized harvesting.

关键词： rice stem vascular gradient stiffness model stem bending temperature stress

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Sequential dual-locking strategy using photoactivated Pt(Ⅳ)-based metallo-nano prodrug for enhanced chemotherapy and photodynamic efficacy by triggering ferroptosis and macrophage polarization

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Acta Pharmaceutica Sinica B 2024年第7期14卷 3251-3265页

作者： Jun Li Qiang Zhang Hao Yang Wenli Lu Yulong Fu Yingcai Xiong Xuan wang Tianming Lu Yanlin Xin Zejuan Xie Weichao Chen guoqiang wang Yuanyuan Guo Ruogu Qi School of Medicine Nanjing University of Chinese MedicineNanjing 210023China Key Laboratory of Mesoscopic Chemistry of Ministry of Education Institute of Theoretical and Computational ChemistrySchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Laboratory for Manufacturing Low Carbon and Functionalized Textiles College of Textiles&ClothingQingdao UniversityQingdao 266071China

Selective activation of Pt(Ⅳ)prodrugs within tumors has emerged as a promising strategy in tumor *** progress has been made with photo-and ultrasound-activated Pt(Ⅳ)prodrugs,concerns remain over the non-specific activation of photosensitizers(PS)and the potential for phototoxicity and chemical *** this study,a sequential dual-locked Pt(Ⅳ)nano-prodrug that can be activated by both the acidic tumor microenvironment and light was *** Pt(Ⅳ)prodrug was prepared by conjugating PS-locked Pt(Ⅳ)to a polymeric core,which was then chelated with metallo iron to lock its photoactivity and form a metallo-nano *** acidic tumor microenvironment conditions,the metallo-nano prodrug undergoes dissociation of iron,triggering a reduction process in oxaliplatin under light irradiation,resulting in the activation of both chemotherapy and photodynamic therapy(PDT).Additionally,the prodrug could induce metallo-triggered ferroptosis and polarization of tumorassociated macrophages(TAM),thereby enhancing tumor *** dual-lock strategy employed in a nanoparticle delivery system represents an expansion in the application of platinum-based anticancer drugs,making it a promising new direction in cancer treatment.

关键词： Dual-locking Pt(Ⅳ)reduction Chemotherapy Photodynamic therapy Ferroptosis Macrophage polarization Medicinal inorganic chemistry Metals in medicine

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Antithetical impacts of deleterious LRP1B mutations in non-squamous and squamous NSCLCs on predicting benefits from immune checkpoint inhibitor alone or with chemotherapy over chemotherapy alone: retrospective analyses of the POPLAR/OAK and CHOICE-01 trial

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Science China Life Sciences 2024年

作者： Jinliang wang Wenyong Zhou Yu Xu Jianchun Duan Qiaoxia Zhou guoqiang wang Leo Li Chunwei Xu Wenxian wang Shangli Cai Zhijie wang Jie wang Department of Oncology The Fifth Medical Center of Chinese PLA General Hospital Department of Thoracic Surgery Shanghai Chest Hospital School of Medicine Shanghai Jiao Tong University Burning Rock Biotech CAMS Key Laboratory of Translational Research on Lung Cancer State Key Laboratory of Molecular Oncology Department of Medical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Basic Medicine and Cancer (IBMC) Chinese Academy of Sciences Department of Clinical Trial The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

In non-small cell lung cancers, the non-squamous and squamous subtypes （nsqNSCLC and sqNSCLC） exhibit disparities in pathophysiology,tumor immunology, and potential genomic correlates affecting responses to immune checkpoint inhibitor （ICI）-based treatments. In our inhouse training cohort （n=85）, the presence of the LRP1B deleterious mutation （LRP1B-del） was associated with longer and shorter progression-free survival （PFS） on ICIs alone in nsqNSCLCs and sqNSCLCs, respectively (Pinteraction=0.008). These results were validated using a larger public ICI cohort (n=208, Pinteraction<0.001). Multiplex immunofluorescence staining revealed an association between LRP1B-del and increased and decreased numbers of tumor-infiltrating CD8+T cells in nsqNSCLCs （P=0.040） and sqNSCLCs （P=0.014）, respectively. In the POPLAR/OAK cohort, nsqNSCLCs with LRP1B-del demonstrated improved PFS benefits from atezolizumab over docetaxel (hazard ratio （HR）=0.70, P=0.046), whereas this benefit was negligible in those without LRP1B-del （HR=1.05, P=0.64）. Conversely, sqNSCLCs without LRP1Bdel benefited more from atezolizumab （HR=0.60, P=0.002） than those with LRP1B-del （HR=1.30, P=0.31）. Consistent results were observed in the in-house CHOICE-01 cohort, in which nsqNSCLCs with LRP1B-del and sqNSCLCs without LRP1B-del benefited more from toripalimab plus chemotherapy than from chemotherapy alone (Pinteraction=0.008). This multi-cohort study delineates the antithetical impacts of LRP1Bdel in nsqNSCLCs and sqNSCLCs on predicting the benefits from ICI alone or with chemotherapy over chemotherapy alone. Our findings highlight the distinct clinical utility of LRP1B-del in guiding treatment choices for nsqNSCLCs and sqNSCLCs, emphasizing the necessity for a detailed analysis based on pathological subtypes when investigating biomarkers for cancer therapeutics.

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基于超球面三元组编码的干扰模式开集识别

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电子与信息学报 2024年第3期46卷 895-905页

作者：高玉龙王国强王钢哈尔滨工业大学电子与信息工程学院哈尔滨150001

干扰模式识别是现代军事通信对抗中必不可少的一环,随着复杂电磁环境当中各种新型恶意干扰样式层出不穷,对于未知型干扰的判决也变得愈发重要。因此,要求干扰模式识别算法保持对于已知型干扰高精度识别的同时,也能够完成对于未知型干扰... 详细信息

干扰模式识别是现代军事通信对抗中必不可少的一环,随着复杂电磁环境当中各种新型恶意干扰样式层出不穷,对于未知型干扰的判决也变得愈发重要。因此,要求干扰模式识别算法保持对于已知型干扰高精度识别的同时,也能够完成对于未知型干扰的判决,以排除未知型恶意干扰的影响。基于此,该文将未知型干扰存在时的干扰模式识别问题建模为开集识别问题,并提出一种基于超球面3元组编码的干扰模式开集识别方法。所提方法基于超球面3元组对输入的时频图像进行降维编码以提高识别精度,然后采用元识别分类器准确地完成干扰模式开集识别任务。通过仿真试验证明该算法在干信比大于–2 dB时能够高效地完成开放空间中的干扰模式识别任务。

关键词：未知型干扰信号开集识别 3元组损失超球面元识别

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基于N-BEATS与辅助编码器的短期电力负荷预测

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电网技术 2024年第4期48卷 1612-1621页

作者：范茜茜王国强罗贺台建玮合肥工业大学管理学院安徽省合肥市230000

短期电力负荷预测的准确性对智能电网平稳高效运行具有重要意义,但多种因素影响下的负荷数据具有较强的非平稳性与随机波动性,使得高精度的短期电力负荷预测面临挑战。为充分挖掘负荷序列中的趋势特征与周期性特征,准确提取与电力负荷... 详细信息

短期电力负荷预测的准确性对智能电网平稳高效运行具有重要意义,但多种因素影响下的负荷数据具有较强的非平稳性与随机波动性,使得高精度的短期电力负荷预测面临挑战。为充分挖掘负荷序列中的趋势特征与周期性特征,准确提取与电力负荷存在潜在相关性的辅助信息特征,提升短期电力负荷预测精度,该文提出了一种基于神经基扩展分析(neural basis expansion analysis,N-BEATS)与辅助编码器的短期电力负荷预测模型。该模型包含两个并行的编码器,基于神经基扩展分析(neural basis expansion analysis,N-BEATS)模型的负荷特征编码器和基于多头注意力机制的辅助信息编码器,分别用于学习负荷数据中的时序特征与辅助信息特征。同时,构建特征融合模块将时序特征和辅助信息特征构造成联合特征向量,并设计基于门控循环单元(gated recurrent unit,GRU)的预测解码器模块进行短期电力负荷预测。在GEFCom2014公开数据集上进行实验,结果表明所提方法与长短期记忆(long short-termmemory,LSTM)网络模型、卷积神经网络(convolutional neural network,CNN)-LSTM网络模型、序列到序列(sequence-to-sequence,Seq2Seq)网络模型、季节自回归差分移动平均(seasonal autoregressive integrated moving average,SARIMA)模型及支持向量回归模型(support vector returns,SVR)等基线模型相比,在预测精度方面具有明显优势,平均绝对百分比误差(mean absolute percentage error,MAPE)平均提升了24.16%。

关键词：短期电力负荷预测神经基扩展分析多头注意力机制特征融合深度学习

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税收征管改革推动全国统一大市场建设的思考

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税务研究 2024年第3期 70-75页

作者：石绍宾张玲欣王国强山东大学经济学院山东大学公共经济与公共政策研究中心国家税务总局济南市税务局

建设全国统一大市场是我国构建新发展格局的基础支撑和内在要求,当前面临要素流动不通畅、配置效率不高、地区分割等突出问题。税收征管改革可以通过提升税收征管的确定性、增强税务执法的规范性、提高税务监管的精准性、强化税务行政... 详细信息

建设全国统一大市场是我国构建新发展格局的基础支撑和内在要求,当前面临要素流动不通畅、配置效率不高、地区分割等突出问题。税收征管改革可以通过提升税收征管的确定性、增强税务执法的规范性、提高税务监管的精准性、强化税务行政的便利性,促进市场统一协调、高效运行、公平竞争和充分开放。近年来,我国不断推进税收征管改革,通过强化区域执法合作、加强征管技术数字化与信息化、完善“放管服”改革等举措助力全国统一大市场建设,取得了较好成效。为进一步推动全国统一大市场建设,税务部门应继续加强税务执法区域协同、推进税收征管数字化建设、加强重点税源管理、持续优化税收营商环境。

关键词：全国统一大市场税收征管税务执法税收营商环境

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南祁连党河南山地区拐杖山岩群玄武岩年代学、地球化学及其构造环境

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中国地质 2024年第3期51卷 965-977页

作者：计波李向民黄博涛王磊王国强中国地质调查局西安地质调查中心自然资源部岩浆作用成矿与找矿重点实验室陕西西安710054 大陆动力学国家重点实验室西北大学地质学系陕西西安710069

【研究目的】前人在南祁连志留纪巴龙贡噶尔组中解体出新元古代拐杖山岩群,对该群中玄武岩的年龄、成因与成岩构造环境的研究是厘清南祁连地区构造演化的重要手段。【研究方法】本文基于LA-ICP-MS锆石U-Pb年龄和全岩地球化学分析等方法... 详细信息

【研究目的】前人在南祁连志留纪巴龙贡噶尔组中解体出新元古代拐杖山岩群,对该群中玄武岩的年龄、成因与成岩构造环境的研究是厘清南祁连地区构造演化的重要手段。【研究方法】本文基于LA-ICP-MS锆石U-Pb年龄和全岩地球化学分析等方法研究拐杖山岩群火山岩的形成年代、地球化学特征及地质意义。【研究结果】锆石U-Pb定年结果显示,玄武岩喷发年龄为(786.6±5.8)Ma,表明拐杖山岩群形成于新元古代早期。岩石地球化学分析结果表明,玄武岩SiO_(2)含量在48.09%~50.97%,高TiO_(2)(1.34%~2.55%),低MgO(5.78%~7.11%),显示亚碱性拉斑玄武岩特征。岩石轻、重稀土分异明显((La/Yb)_(N)=3.76~4.51),无明显Eu异常(δEu=0.80~1.05),大离子亲石元素Ba、Th、U相对富集,Pb强富集,亏损Nb、Ta、Ti等高场强元素。【结论】岩石地球化学特征暗示拐杖山岩群玄武岩是遭受陆壳物质混染的地幔源区玄武岩,该火山岩形成于大陆裂谷环境,响应了全球新元古代Rodinia超大陆裂解事件。

关键词：锆石U-Pb定年玄武岩拐杖山岩群构造环境地质调查工程南祁连

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