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Effects of probiotics， prebiotics and synbiotics supplementation on cardiovascular risk factors in patients with type 2 diabetes mellitus: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials

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Food Science and Human Wellness 2024年

作者： Yanyan Tian Jiayue Xia Lihua Li Ligang Yang Hua xiao guoping Gao Yuanyuan Wang Chen Zhang Tiange Bu Guiju Sun Department of Nutritional Sciences， University of Toronto Key Laboratory of Environmental Medicine and Engineering of Ministry of Education， Department of Nutrition and Food Hygiene， School of Public Health， Southeast University Lianshui People's Hospital Affiliated to Kangda College of Nanjing Medical University Gong'an County People's Hospital

A systematic review and meta-analysis study was conducted to assess the effectiveness of probiotic/prebiotic/synbiotic supplementation on the effects of cardiovascular risk factors in patients with type 2 diabetes mellitus (T2DM) based on data from randomized controlled trials (RCTs). We searched electronic databases including PubMed， Cochrane Library， Embase， and Web of Science to identify clinical trials published up to 31 March 2023. Data was pooled using a random-effects model if significant heterogeneity (I2> 50%)， otherwise use a fixed-effects model. Fifty-six trials that included 3 317 patients were enrolled for analysis. Meta-analysis reported that probiotic/prebiotic/synbiotic supplementation significantly reduced systolic blood pressure (SBP) (weighted mean difference (WMD): -3.57 mmHg， 95% confidence interval (CI): -5.36， -1.78; P = 0.000)， diastolic blood pressure (DBP) (WMD: -2.05 mmHg， 95% CI: -3.07， -1.04; P = 0.000)， triglycerides (TG) (WMD: -16.10 mg/dL， 95% CI: -20.16， -12.05; P = 0.000)， total cholesterol (TC) (WMD: -14.00 mg/dL， 95% CI: -20.46， -7.55; P = 0.000)， low-density lipoprotein cholesterol (LDL-C) (WMD: -7.03 mg/dL， 95% CI: -9.25， -4.81; P = 0.000)， fasting plasma glucose (FPG) (WMD: -16.57 mg/dL， 95% CI: -20.39， -12.74; P = 0.000)， hemoglobin A1c (HbA1c) (WMD: -0.44%， 95% CI: -0.68， -0.20; P = 0.000)， insulin (standardized mean difference (SMD): -0.37， 95% CI: -0.53， -0.21; P = 0.000)， homeostatic model assessment of insulin resistance (HOMA-IR) (WMD: -1.05， 95% CI: -1.56， -0.54; P = 0.000)， C-reactive protein (CRP) (SMD: -0.35， 95% CI: -0.57， -0.13; P = 0.002)， tumor necrosis factor-α (TNF-α) (SMD: -1.07， 95% CI: -1.57， -0.56; P = 0.000)， interleukin-6 (IL-6) (SMD: -0.37 ， 95% CI: -0.61， -0.13; P = 0.003) levels， they also increased the high-density lipoprotein cholesterol (HDL-C) (WMD: 3.70 mg/dL， 95% CI: 1.80， 5.60; P = 0.000) levels in T2DM patients， as compared to the placebo groups. This meta-analysis supports the use of probiotic

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Realization of one-dimensional 2^(n)-root topological states in photonic lattices

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Science China(Technological Sciences) 2024年第1期67卷 98-104页

作者： WEI RuiShan ZHANG QingLong YANG DanDan HUANG XiongJian PAN QiWen KANG Juan QIU JianRong YANG ZhongMin DONG guoping State Key Laboratory of Luminescent Materials and Devices and Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied TechniquesGuangdong Engineering Technology Research and Development Center of Special Optical Fiber Materials and DevicesSchool of Materials Science and EngineeringSouth China University of TechnologyGuangzhou 510640China School of Physics and Optoelectronics South China University of TechnologyGuangzhou 510640China State Key Laboratory of Modern Optical Instrumentation College of Optical Science and EngineeringZhejiang UniversityHangzhou 310027China

Square-root topological insulators recently discovered are intriguing topological *** possess topological properties inherited from the squared Hamiltonian and exhibit double-band *** mechanism of the square root was generalized to 2^(n)-root topological insulators,giving rise to more band *** this study,we describe the experimental realization of onedimensional 2^(n)-root topological insulators in photonic waveguide arrays using the archetypical Su-Schrieffer-Heeger(SSH)*** edge states with tunable numbers are clearly observed under visible *** particular,we visualized the dynamic evolutions of the light propagation by varying the sample lengths,which further proved the localization and multiple numbers of edge states in 2^(n)-root topological *** experiment,which involves constructing 2^(n)-root topological photonic lattices in various geometric arrangements,provides a stable platform for studying topological states that exhibit a remarkable degree of flexibility and control.

关键词： 2^(n)-root topological insulators multiple edge states photonic waveguide arrays light dynamics

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A review on ultra-small undoped MoS_(2) as advanced catalysts for renewable fuel production

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Carbon Energy 2024年第2期6卷 92-112页

作者： guoping Liu Lingling Ding Yuxuan Meng Ahmad Ali Guifu Zuo Xianguang Meng Kun Chang Oi Lun Li Jinhua Ye Hebei Provincial Laboratory of Inorganic Nonmetallic Materials College of Materials Science and EngineeringNorth China University of Science and TechnologyTangshanChina College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjingChina School of Materials Science and Engineering Pusan National UniversityBusanKorea International Center for Materials Nanoarchitectonics(WPIMANA) National Institute for Materials Science(NIMS)1-1 NamikiTsukubaIbarakiJapan

Molybdenum disulfide(MoS_(2))has garnered significant attention in the field of catalysis due to the high density of active sites in its unique two-dimensional(2D)structure,which could be developed into numerous high-performance *** synthesis of ultra-small MoS2 particles(<10 nm)is highly desired in various experimental *** ultra-small structure could often lead to a distinct S-Mo coordination state and nonstoichiometric composition in MoSx,minimizing in-plane active sites of the 2D structure and making it probable to regulate the atomic and electronic structure of its intrinsic active sites on a large extent,especially in MoSx *** article summarizes the recent progress of catalysis over ultra-small undoped MoS_(2) particles for renewable fuel *** a systematic review of their synthesis,structural,and spectral characteristics,as well as the relationship between their catalytic performance and inherent defects,we aim to provide insights into catalysis over this matrix that may potentially enable advancement in the development of high-performance MoS_(2)-based catalysts for sustainable energy generation in the future.

关键词： applications catalytic MoS_(2) structure synthesis

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Enhancement of catalytic activity for hydrogenation of nitroaromatic by anionic metal-organic framework

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Chinese Chemical Letters 2024年第3期35卷 144-148页

作者： Qi Wu Anyang Li Ruibo He Yaxi Wu Lei Hou guoping Yang Wenyan Zhang Yao-Yu Wang Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education College of Chemistry&Materials ScienceNorthwest UniversityXi'an 710127China

Nitroaromatic hydrogenation catalysis without precious metals remains a longstanding *** rate of electron transfer is the crucial factor affecting hydrogenation ***,an ionic Cd-based metal-organic framework(I-Cd-MOF)exhibiting a unique structure with one-dimensional(1D)opening nanochannels and good electron transfer ability was synthesized for catalyzing hydrogenation of 4-nitrophenol(4-NP).The catalytic activity of the unique I-Cd-MOF without noble metals is detected,which is higher than most reported noble metal ***,the reaction rate of I-Cd-MOF(4.28 min^(-1))is about 47.6 times higher than that of the Cd-based neutral MOF(N-Cd-MOF)with the similar crystalline *** chromatograph mass spectrometer(LC-MS)and theoretical results demonstrate that 4-NP and five intermediates are stabilized in the channels of I-Cd-MOF,which increases the possibility of contact with H^*and H_(2)g enerated at the Cd *** I-Cd-MOF was extended to other nitroaromatic hydrogenation catalysis,which still displays excellent *** importantly,the I-MOF@Filter membrane was successfully constructed for continuous hydrogenation catalytic reactions,which maintains a high catalytic performance after 7 cycles of recycling without *** work fills in the application of the I-MOFs in hydrogenation catalytic reactions and provides an effective way for the rapid and green degradation of nitroaromatic compounds.

关键词： Anions Metal-organic frameworks Catalysis Electron transfer Hydrogen production

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STING mediates microglial pyroptosis via interaction with NLRP3 in cerebral ischaemic stroke

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Stroke & Vascular Neurology 2024年第2期9卷 153-164页

作者： Wenyu Li Nan Shen Lingqi Kong Hongmei Huang Xinyue Wang Yan Zhang guoping Wang Pengfei Xu Wei Hu Department of Neurology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhuiChina

background Ischaemia-evoked neuroinflammation is a critical pathogenic event following ischaemic *** D(GSDMD)-associated pyroptosis represents a type of inflammation-associated programmed cell death,which can exacerbate neuroinflammatory responses and brain *** of interferon genes(STING)was recently described as a vital innate immune adaptor protein associated with ***,the regulatory effects of STING on microglial pyroptosis post-stroke have not been well *** STING-knockout and wild-type(WT)mice were subjected to middle cerebral artery occlusion(MCAO).STING small interfering RNA(siRNA)was transfected into BV2 cells before oxygen-glucose deprivation/reoxygenation(OGD/R).STING-overexpressing adeno-associated virus(AAV)and NOD-like receptor family pyrin domain containing 3(NLRP3)siRNA were administered by stereotaxic injection.2,3,5-Triphenyl tetrazolium chloride(TTC)staining,TdT-mediated dUTP nick end labeling(TUNEL)staining,Fluoro-Jade C(FJC)staining,neurobehavioural tests,immunohistochemistry,cytokine antibody array assay,transmission electron microscopy,immunoblot,Enzyme-linked immunosorbent assay(ELISA)and quantitative real-time polymerase chain reaction(qRT-PCR)were carried ***-immunoprecipitation assays were used to investigate the interplay between STING and *** STING expression was increased after MCAO and mainly detected on *** deletion alleviated brain infarction,neuronal damage and neurobehavioural impairment in mice subjected to *** knockout suppressed microglial activation and the secretion of inflammatory chemokines,accompanied by mitigation of microglial *** upregulation of microglial STING by AAV-F4/80-STING aggravated brain injury and microglial ***,co-immunoprecipitation showed that STING bound to NLRP3 in *** of NLRP3 siRNA reversed AAV-F4/80-STING-induced deterioration of microglial pyropt

关键词： NLRP3 cerebral inflammation

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An Automatic Implementation of Oropharyngeal Swab Sampling for Diagnosing Respiratory Infectious Diseases via Soft Robotic End-Effectors

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Chinese Journal of Mechanical Engineering 2024年第2期37卷 55-67页

作者： Yafeng Cui Wenjie Yu Jingjing Li Qi Shao Ding Weng guoping Yin xiaohao Zhang Xinjun Liu Jingying Ye Jiadao Wang Huichan Zhao Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China Beijing Huakang Tongbang Technology Company Beijing 102609China Department of Otorhinolaryngology Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing 102218China Tianjin Research Institute for Advanced Equipment Tsinghua UniversityTianjin 300300China

The most widely adopted method for diagnosing respiratory infectious diseases is to conduct polymerase chain reaction(PCR)assays on patients’respiratory specimens,which are collected through either nasal or oropharyngeal *** manual swab sampling process poses a high risk to the examiner and may cause false-negative results owing to improper *** this paper,we propose a pneumatically actuated soft end-effector specifically designed to achieve all of the tasks involved in swab *** soft end-effector utilizes circumferential instability to ensure grasping stability,and exhibits several key properties,including high load-to-weight ratio,error tolerance,and variable swab-tip stiffness,leading to successful automatic robotic oropharyngeal swab sampling,from loosening and tightening the transport medium tube cap,holding the swab,and conducting sampling,to snapping off the swab tail and sterilizing *** an industrial collaborative robotic arm,we integrated the soft end-effector,force sensor,camera,lights,and remote-control stick,and developed a robotic oropharyngeal swab sampling *** this swab sampling system,we conducted oropharyngeal swab-sampling tests on 20 *** Digital PCR assay results(RNase P RNA gene absolute copy numbers for the samples)revealed that our system successfully collected sufficient numbers of cells from the pharyngeal wall for respiratory disease *** summary,we have developed a pharyngeal swab-sampling system based on an“enveloping”soft actuator,studied the sampling process,and imple-mented whole-process robotic oropharyngeal swab-sampling.

关键词： Diagnosis Medical robot Soft end-effector Swab-sampling Digital PCR

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Fine-tuning redox ability of arylene-bridged bis(benzimidazolium)for electrochromism and visible-light photocatalysis

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Chinese Chemical Letters 2024年第9期35卷 140-144页

作者： Jing Wang Zenghui Li xiaoyang Liu Bochao Su Honghong Gong Chao Feng guoping Li Gang He Bin Rao School of Chemistry Engineering Research Center of Energy Storage Materials and DevicesMinistry of EducationXi’an Key Laboratory of Sustainable Energy Materials ChemistryXi’an Jiaotong UniversityXi’an 710054China Frontier Institute of Science and Technology Xi’an Jiaotong UniversityXi’an 710054China Instrumental Analysis Center Xi’an Jiaotong UniversityXi’an 710049China

In this study,a series of arylene-bridged bis(benzimidazolium)triflates 1^(–)6^(^(2+))·2[OTf^(–)]were synthesized by grafting differentπ-linkers with benzimidazolium *** them,compound 1^(2+)·2[OTf^(–)]with anthracene as the linker exhibited remarkable electron transfer capabilities across four distinct redox *** inclusion of an anthracene unit as theπ-linker contributes to its exceptional redox and optoelectronic ***,1^(2+)·2[OTf^(–)]was successfully utilized as both an electrochromic molecule in an ECD under applied voltage for the first time,and a highly efficient photocatalyst for the formation of carbon–phosphorus bonds via visible-light-induced cross-dehydrogenative coupling reactions.

关键词： N-Heterocyclic carbenes(NHCs) Ionic radicals Electrochromism Photocatalysis

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Light demand characteristics,production performance,and changes in the feeding patterns of broilers

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International Journal of Agricultural and Biological Engineering 2024年第2期17卷 68-73页

作者： Shouyi Wang guoping Jiang Chenghao Pan Thebano Santos Yasser Elhadidi Ahmed Jado Shufang Jin Jinming Pan College of Biosystems Engineering and Food Science Zhejiang UniversityHangzhou 310058China Infinova(Hangzhou)Information System Technology Co. Ltd.Hangzhou 310012China Center of Information Technology"Renato Archer"(CIT) Ministry of ScienceTechnologyInnovation and CommunicationCEP:13069-901 Campinas(SP)Brazil Department of Agricultural Engineering Mansoura UniversityMansoura 35516Egypt

Poultry is a light-sensitive animal and the light environment has an important influence on the growth and development of these *** studies have mainly focused on the effects of the light environment on various physiological indicators of poultry but seldom explored the light demand characteristics of broilers under free *** experiment mainly studied the light demand characteristics of broilers under a yellow LED light environment and the influence of different breeding densities[low-density(2.5 broilers/m^(2)),high-density(7.5 broilers/m^(2))]on the production performance and diet characteristics of *** showed that the production performance indexes of low-density groups are higher than those of high-density *** feed and water consumption in the light area of the two experimental groups were significantly higher than those in the dark area,which means that the broilers showed a great preference for the light ***,as the age of the broilers increased,the food and water consumption of the broilers decreased,indicating that broilers had a lower preference for light in the middle and late stages of *** statistical results for the residence frequency distribution characteristics showed that broiler chickens had different light requirements at different growth stages under the condition of active selection:1)low-density breeding environment:23.8L(light):0.2D(dark)for chicks and 22.3L:1.7D for adult broilers;2)high-density breeding environment:22.6L:1.4D for chicks and 15.0L:9.0D for adult *** study will provide a reference for the optimization and control of light environment in broiler breeding.

关键词： broiler light-demand characteristics production performance feeding pattern

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Synergistic effect of homojunction and Ohmic junctions in CdS boosting spatial charge separation for U(VI)photoreduction

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Nano Research 2024年第8期17卷 6849-6859页

作者： Haonan Pei Zhimin Dong Zifan Li Jian Huang Yuanping Jiang Zuojia Li Lin Xu xiaohong Cao Yunhai Liu Zhibin Zhang guoping Yang State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China

Photo-excited holes usually migrate to the surface of the catalyst and rapidly recombine with electrons,reducing the photocatalytic reduction efficiency of uranium(VI)(U(VI))in radioactive ***,we employed a straightforward synthesis technique to meticulously shape and manipulate the morphology of CdS to precisely construct CdS-Ni dandelion-like composites with different aspect ***,the introduction of crystal facet homojunction with Ohmic contacts in this unique morphology siqnificantly improves the photocatalytic ***-dependent photoluminescence spectroscopy(TD-PL)verifies that the composite material positively effects on the dissociation of *** 30 min,CdS(002)/(102)/Ni-4 removed 98% of the uranium content in solution and showed a rather high apparent rate constant(0.114 min^(−1)),which was 4.8 times higher than that of CdS nanospheres(NSs)(0.024 min^(−1))and 3.7 times higher than that of CdS nanorods(NRs)(0.031 min^(−1)).This is much higher the most reported photocatalysts for U(VI)*** after 5 consecutive cycles,the photocatalytic efficiency only decreased by 7%.This offers a fresh perspective on constructing a new perspective for building a green,efficient,and multi mechanism collaborative catalytic system to remediate environmental pollution.

关键词： uranium dandelion-shaped axial size effect crystal facet homojunction ohmic contact

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LASTIKA-13沥青混合料级配设计与性能研究

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公路工程 2015年第4期40卷 90-94页

作者：肖国平王辉胡小华王旺沪昆高速公路潭市互通工程建设项目部湖南湘潭411400 长沙理工大学交通运输工程学院湖南长沙410114

通过正交试验分析提出了LASTIIKA-13级配的推荐范围,根据级配范围优化结果,设计了LASTIKA-13沥青混合料。进而采用LASTIKA-13和分别以Superflex与SBS改性沥青为胶结料的AC-13共3种不同类型的改性沥青混合料,进行高温车辙、低温弯曲、水... 详细信息

通过正交试验分析提出了LASTIIKA-13级配的推荐范围,根据级配范围优化结果,设计了LASTIKA-13沥青混合料。进而采用LASTIKA-13和分别以Superflex与SBS改性沥青为胶结料的AC-13共3种不同类型的改性沥青混合料,进行高温车辙、低温弯曲、水稳性、小梁弯曲疲劳等路用性能对比试验;试验结果表明LASTIKA-13改性沥青混合料具备优良的高温性能及抗水损能力;同时LASTIKA-13改性沥青混合料较其他2种混合料而言,具有低温性能受低温温度变化的影响最小,疲劳性能对荷载变化的敏感性最低等优点,因而具有更好的低温性能、粘结性能与耐疲劳性能,能有效延长路面使用寿命。

关键词： LASTIKA-13 Superflex改性沥青级配优化路用性能

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