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重庆市永川区60岁及以上老年人非婚性行为特征及相关因素调查

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中华流行病学杂志 2024年第9期45卷 1239-1243页

作者：林璟吴国辉贺亚萍谭天宇重庆市疾病预防控制中心性病艾滋病预防控制所重庆400707

目的分析≥60岁老年人非婚性行为特征及相关因素,为老年人群的艾滋病防控提供参考依据。方法2022年9-12月在重庆市永川区招募居住≥6个月的≥60岁老年人开展横断面调查,采用多阶段抽样方法,样本量为2721人。收集调查对象人口学特征、艾... 详细信息

目的分析≥60岁老年人非婚性行为特征及相关因素,为老年人群的艾滋病防控提供参考依据。方法2022年9-12月在重庆市永川区招募居住≥6个月的≥60岁老年人开展横断面调查,采用多阶段抽样方法,样本量为2721人。收集调查对象人口学特征、艾滋病防治知识和性行为等信息,采用logistic回归模型分析调查对象发生非婚性行为的相关因素。采用SPSS 23.0软件进行统计学分析。结果≥60岁老年人调查对象共3000人,有效问卷2974份,男女性别比为1∶1(1488∶1486),年龄(69.3±7.0)岁,艾滋病防治知识知晓率为78.5%(2336/2974)。最近1年发生性行为的比例为26.9%(801/2974),最近1年与配偶发生性行为的比例为20.9%(493/2350),发生非婚性行为的比例为10.8%(322/2974),发生商业性行为比例为10.2%(304/2974),发生非婚非商业性行为的比例为1.2%(36/2974)。多因素logistic回归分析结果显示,≥60岁老年人发生非婚性行为的相关因素包括男性(aOR=89.08,95%CI:36.30~218.60)、70~79岁(aOR=1.93,95%CI:1.44~2.59)和≥80岁(aOR=2.41,95%CI:1.56~3.74)、艾滋病防治知识不知晓(aOR=2.72,95%CI:2.04~3.64)。结论重庆市永川区≥60岁老年人发生非婚性行为的比例较高,应关注老年人群的性需求和性健康,提高其艾滋病防治知识水平,倡导安全性行为,提高其性健康和生活质量。

关键词：老年人非婚性行为艾滋病

CD4^(+)T淋巴细胞及身体成分与重庆市老年HIV感染者生理衰弱的关联分析

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中华预防医学杂志 2024年第2期58卷 235-240页

作者：陈晨徐杰江震吴国辉张裕强赵燕吴尊友中国疾病预防控制中心性病艾滋病预防控制中心北京102206 重庆市疾病预防控制中心重庆400042 重庆市江津区疾病预防控制中心性病艾滋病预防控制科重庆402260 中国疾病预防控制中心性病艾滋病预防控制中心治疗与关怀室北京102206

目的探索CD4^(+)T淋巴细胞(CD4细胞)计数水平与老年HIV感染者生理衰弱患病的关联关系及体成分指标对二者的修饰作用。方法2022年5—10月于重庆市江津区疾病预防控制中心辖区内7家抗病毒治疗点招募485例接受抗反转录病毒治疗(ART)的老年... 详细信息

目的探索CD4^(+)T淋巴细胞(CD4细胞)计数水平与老年HIV感染者生理衰弱患病的关联关系及体成分指标对二者的修饰作用。方法2022年5—10月于重庆市江津区疾病预防控制中心辖区内7家抗病毒治疗点招募485例接受抗反转录病毒治疗(ART)的老年HIV感染者。采用自制问卷通过面对面调查收集对象基本特征(年龄和性别)、生活习惯(吸烟和饮酒情况)和疾病史情况(包括代谢性疾病、心脑血管疾病、呼吸系统疾病和恶性肿瘤)等资料。采用Fried量表评估研究对象的生理衰弱情况。进行体质(步速、握力、身高和体重)和体成分(骨骼肌量、体脂肪量和基础代谢率)测量。由中国艾滋病综合防治数据信息管理系统获取对象抗反转录病毒治疗资料。计算老年感染者生理衰弱现患率,采用多因素logistic回归探索不同CD4水平对老年HIV感染者生理衰弱的影响,并对体成分指标进行亚组分析探索是否存在交互作用。结果485例对象年龄为(72±5)岁,其中>70岁者占48.2%(234例),男性占70.9%(344例),且已全部启动抗病毒治疗。老年HIV感染者生理衰弱率为7.4%(36/485)。多因素logistic回归模型分析显示:调整年龄、性别、吸烟、饮酒、体成分指标、ART时长、病毒载量和合并症数量等因素后,CD4细胞水平增加与老年HIV感染者生理衰弱患病风险下降相关;CD4细胞每增加5.0×10^(7)个/L,老年感染者生理衰弱患病风险下降12%[OR(95%CI):0.88(0.76~1.01)];与CD4细胞低水平组相比,CD4细胞正常水平组生理衰弱风险下降69%[OR(95%CI):0.31(0.10~0.92)]。体成分指标亚组分析显示:CD4细胞水平与生理衰弱的关联在高骨骼肌量和高基础代谢率感染者中更强(P交互值<0.05)。结论重庆市老年HIV感染者生理衰弱率相对较低;CD4细胞水平、骨骼肌量和基础代谢率与生理衰弱有关联。

关键词： HIV 老年人 CD4^(+)T淋巴细胞身体成分生理衰弱

2011—2021年重庆市艾滋病流行特征分析

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实用预防医学 2024年第4期31卷 393-396页

作者：贺亚萍周超吴国辉张维重庆市疾病预防控制中心重庆400042

目的分析2011—2021年重庆市艾滋病流行疫情特征,为制定艾滋病防控策略提供参考依据。方法从中国疾病预防控制信息系统艾滋病综合防治信息系统下载2011—2021年重庆市报告的HIV/AIDS病例数,分析其时间、人群和地域分布等特征,P<0.05为... 详细信息

目的分析2011—2021年重庆市艾滋病流行疫情特征,为制定艾滋病防控策略提供参考依据。方法从中国疾病预防控制信息系统艾滋病综合防治信息系统下载2011—2021年重庆市报告的HIV/AIDS病例数,分析其时间、人群和地域分布等特征,P<0.05为差异有统计学意义。结果2011—2021年累计报告HIV/AIDS 71221例,新报告病例数从2011年的3016例上升至2021年的8072例,总体呈上升趋势。病例以男性(75.6%)、农民(37.3%)、小学文化(34.8%)人群为主,年龄以≥50岁为主(50.5%),且≥50岁病例构成比呈逐年上升的趋势(χ_(趋势)^(2)=3377.030,P=0.000)。主城都市区聚集了83.1%的病例,78.8%的病例通过异性性行为感染HIV,检出途径以医疗机构检出为主,占57.6%。结论2011—2021年重庆市艾滋病疫情整体呈上升趋势,≥50岁人群防治工作形势严峻,性传播是当前主要的传播途径,需要进一步加强重点人群性传播方面的干预。

关键词：艾滋病疫情形势流行特征

Analysis of clinical efficacy of different initial antimicrobial treatment in healthcare associated pneumonia patients in emergency department

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Chinese Medical Journal 2014年第10期127卷 1814-1819页

作者： Cao guohui Chen Xuyan wu Sheng Department of Emergency Medicine Peking University First Hospital Beijing 100034 China

Background Community acquired pneumonia （CAP） is one of the most common infectious disease in emergency *** 2005 the concept of healthcare associated pneumonia （HCAP） was proposed by the ATS/IDSA *** clinical features and microbiology of HCAP are different from CAP,however,the initial antimicrobial treatment is still *** aimed to compare the clinical efficacy between HCAP patients treated initially with HCAP guidelineconcordant antimicrobial agents and those with CAP guideline-concordant antimicrobial *** We conducted a retrospective observational study on HCAP patients who were admitted to emergency department between December 2011 and December *** were divided into 2 groups according to their different initial antimicrobial *** compared clinical features,distribution of pathogen,severity,days and spending on intravenous antimicrobial,length and charge of hospitalization and clinical outcomes,and meanwhile analyzed the clinical efficacy as *** Of the 125 HCAP patients,55 patients received CAP guideline-concordant antimicrobial agents and 70 received HCAP *** major pathogens were Klebsiella pneumoniae,methicillin-resistant staphylococcus aureus （MRSA）,Pseudomonas aeruginosa and Escherichia coll The 2 groups were similar at baseline,including old age,comorbidities,Pneumonia Severity Index scores,APACHE scores,and length of intravenous antimicrobial use and hospitalization duration,and in-hospital *** efficacy rate occurred in 70.0％ of HCAP agent patients and 50.9％ of CAP agent patients （P=0.029）.Antimicrobial charge and total hospital charge for HCAP agent patients were significantly higher than that for CAP agent *** Initial treatment of HCAP patients in emergency department with HCAP guideline-concordant antimicrobial could increase clinical efficacy rate,as well as antimicrobial charge and total hospital charge,but was not associated with shortening the l

关键词： pneumonia health care drug resistance treatment efficacy

Prevalence and risk factors of HIV and syphilis,and knowledge and risk behaviors related to HIV/AIDS among men who have sex with men in Chongqing,China

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The Journal of Biomedical Research 2016年第2期30卷 101-111页

作者： Wenzhe Ma guohui wu Hui Zheng Wenjuan Zhang Zhihang Peng Rongbin Yu NingWang Department of Epidemiology and Biostatistics School of Public Health Nanjing Medical University Nanjing Jiangsu 211166 China Chongqing Center for Disease Control and Prevention Chongqing China National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China

High HIV prevalence and incidence burdens have been reported in men who have sex with men（MSM）in Chongqing,*** aimed to estimate the prevalence of HIV and other sexually transmitted infections（STIs）,to appraise the knowledge and risk behaviors related to HIV/AIDS among MSM,and to analyze the possible causes of deviation between behavior and knowledge to make better *** recruited 617 MSM from February to July in 2008 by using a respondent-driven sampling（RDS） method in Chongqing,*** the collection of questionnaire-based data and biological testing results from all objects,we launched a crosssectional ***/SE was used for data analysis by frequency,ANOVA,rank sum test and logistic regression *** with syphilis（OR=4.16,95%CI：2.35-7.33,P〈0.0001） were more likely to be HIV *** a company employee（OR=3.64,95%CI：1.22-10.08,P〈0.0001） and having bought male for sex（OR=3.52,95%CI：1.10-11.32,P〈0.034） were associated with a higher probability of *** with younger age,higher education and greater monthly income had a higher mean knowledge *** who had HIV testing had a higher mean knowledge score than those who never ***,venues for finding sex partners by Internet and homosexuals in MSM had a higher mean knowledge score compared to other occupations,venues for finding sex partners and sexual *** is an urgent need for delivery of barrier and biomedical interventions with coordinated behavioral and structural strategies to improve the effect of HIV interventions among MSM.

关键词： HIV/AIDS men who have sex with men Chongqing China

磁共振弥散加权成像联合高分辨率T_(2)加权成像序列在肛瘘合并脓肿患者术前诊断中的价值分析

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当代医学 2024年第9期30卷 89-93页

作者：周菲菲鲁思明仇志亮钱坤吴国辉上饶市人民医院影像科江西上饶334000

目的探讨MRI弥散加权成像(DWI)联合高分辨率T2加权成像(T_(2)WI)序列检查在肛瘘合并脓肿患者术前诊断中的价值。方法选取2020年1月至2021年12月于上饶市人民医院就诊的66例疑为肛瘘合并脓肿患者作为研究对象。所有患者均行MRI扫描,以手... 详细信息

目的探讨MRI弥散加权成像(DWI)联合高分辨率T2加权成像(T_(2)WI)序列检查在肛瘘合并脓肿患者术前诊断中的价值。方法选取2020年1月至2021年12月于上饶市人民医院就诊的66例疑为肛瘘合并脓肿患者作为研究对象。所有患者均行MRI扫描,以手术检查结果为金标准,分析DWI联合T_(2)WI-FS及单独使用T_(2)WI-FS序列对肛瘘合并脓肿患者的诊断效能。结果66例患者经手术探查均存在肛瘘合并脓肿,证实瘘管86支,肛瘘内口72个。其中,括约肌间型29例,经括约肌型21例,括约肌上型9例,括约肌外型7例。瘘管分级:Ⅰ级36支,Ⅱ级25支,Ⅲ级17支,Ⅳ级6支,Ⅴ级2支。T_(2)WI-FS序列检出瘘管62支,肛瘘内口57个,准确度为79.17%,其中,括约肌间型35例,经括约肌型16例,括约肌上型8例,括约肌外型7例;瘘管分级:Ⅰ级27支,Ⅱ级18支,Ⅲ级12支,Ⅳ级4支,Ⅴ级1支。DWI联合T_(2)WI-FS序列检出瘘管83支,肛瘘内口71个。其中,括约肌间型30例,经括约肌型20例,括约肌上型9例,括约肌外型7例。瘘管分级:Ⅰ级35支,Ⅱ级24支,Ⅲ级16支,Ⅳ级6支,Ⅴ级2支。单独DWI联合T_(2)WI-FS序列括约肌间型(特异度、准确度、阳性预测值)、经括约肌型(灵敏度、特异度)、括约肌上型(灵敏度、特异度、准确度、阳性预测值、阴性预测值)及括约肌外型的准确度均高于T_(2)WI-FS,差异有统计学意义(P<0.05),其余两两比较差异无统计学意义。单独DWI联合T_(2)WI-FS序列Ⅰ级(灵敏度、准确度、阳性预测值)、Ⅱ级(灵敏度、准确度)、Ⅲ级(准确度)均高于T_(2)WI-FS,差异有统计学意义(P<0.05),其余两两比较差异无统计学意义。结论DWI联合T_(2)WI-FS序列对肛瘘合并脓肿患者脓肿部位、瘘管分级的诊断价值均较高,对患者术前诊断有一定的优势。

关键词：弥散加权成像高分辨率T_(2)加权像肛瘘肛周脓肿

Comparative study of the effects of Tartary buckwheat seed and sprout consumption on the physiological indices and gut microbiota of C57BL/6J mice

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Food Science and Human Wellness 2024年第2期13卷 791-800页

作者： guohui Nan Haixia Zhao Qiong wu Lisong Liu Zichao Guan Chenglei Li Huala wu Dabing Xiang Qi wu College of Life Science Sichuan Agricultural UniversityYa'an 625014China Faculty of Quality Management and Inspection&Quarantine Yibin UniversityYibin 644000China College of Pharmacy and Biological Engineering Chengdu UniversityChengdu 610106China

Tartary buckwheat(Fagopyrum tataricum)is a well-known pseudocereal for its health and economic ***,abundant antinutritional factors(ANFs)reduces its health *** reported,germination can improve the nutritional profile of *** this study,we systematically evaluate the safety of Tartary buckwheat seeds(TB)and Tartary buckwheat sprouts(TBS)used as high active *** evaluating nutrition levels,bioactive compounds and ANFs in TBS during germinating,5^(th)-day TBS were selected as the raw material.C57BL/6J mice were gavaged daily with distilled water,TB,or TBS for 6 *** physiological indices related to ANFs were *** showed that the TB intake tends to generate negative effects on the gut microbiota,and ***,upon TB intake,the Fe^(3+)content in serum,trypsin activity in pancreas and jejunum decreased,while the cytokine,IgE,and histamine levels in serum,water content in faeces,cytokine levels in liver and jejunum ***,TBS did not induce any obvious negative effects on the above relevant indices and showed better lipid-lowering ***,TBS are safer and more effective as a raw material to produce the functional food for long-term consumption with the intention of preventing and treating hyperlipidaemia.

关键词： Tartary buckwheat Tartary buckwheat sprouts Antinutritional factors Gut microbiota Health effect

Far Field Solution of SH-wave by Circular Hole and Linear Crack

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Far Field Solution of SH-wave by Circular Hole and Linear Cr...

Study on Information Transmission Technologies in Future Antiterrorism Sensor Network

2005国际机械工程与力学会议

作者： guohui wu Hongliang LI Zailin YANG School of Civil Engineering Harbin Engineering University

Circular hole is used widely in structure design. In this paper, the method of Green’s function is used to investigate the problem of far field solution of circular hole and linear crack impacted by incident SH-wave. Firstly, a Green’s function is constructed for the problem, which is a fundamental solution of displacement field for an elastic space possessing a circular hole while bearing out-of-plane harmonic line source force at any point;Secondly, in terms of the solution of SH-wave’s scattering by an elastic space with a circular hole, anti-plane stresses which are the same in quantity but opposite in direction to those mentioned before, are loaded at the region where the linear crack is in existent actually, we called this process "crack-division";Finally, the expressions of the displacement and stresses are given when the circular hole and linear crack exist at the same time. Then, when the special Green’s function has been constructed and close field solution has been illustrated, the far field of scattered wave is studied. The displacement mode of scattered wave at far field and scattering cross-section are given. Numerical results are illustrated and the influence of wave number, incident angles of SH-wave, the location of the cracks are discussed. The results can be applied in the study of fracture, and undamaged frame crack detection.

关键词： crack circular hole Green’s Function SH-wave scattering displacement mode of scattered wave at far field scattered cross-section

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Study on Information Transmission Technologies in Future Ant...