检索结果-南通市图书馆

China CDC weekly 2024年第15期6卷 305-311,I0001-I0004页

作者： Yanxia Sun Yuping Duan Jie Qian Yimin Qu Ye Wang guohui fan Qiangru Huang Zhongjie Li Weizhong Yang Luzhao Feng State Key Laboratory of Respiratory Health and Multimorbidity Key Laboratory of Pathogen Infection Prevention and ControlMinistry of EducationSchool of Population Medicine and Public HealthChinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina

What is already known about this topic?Individuals who initially contract severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)lack significant mixed ***,it is crucial to monitor the clinical characteristics and associated factors of these individuals in order to inform *** is added by this report?The common symptoms reported were fever,cough,and sore *** and receiving four vaccination doses within a 6-month period were found to be associated with a shorter duration of virus shedding,decreased hospitalization rate,and reduced risk of *** aged 60 years and older,as well as those with underlying medical conditions,had a higher risk of developing *** are the implication for public health practices?Online surveys conducted through social media platforms have the potential to complement disease surveillance and data collection *** terms of vaccination prioritization,it is recommended to prioritize older individuals and those with underlying diseases.

关键词： doses Online initially

应急状态下新冠流行曲线预测的方法学研究——基于北京市百度搜索和传统流感样病例监测

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Engineering 2023年第12期31卷 112-119页

作者： Ting Zhang Liuyang Yang Xuan Han guohui fan Jie Qian Xuancheng Hu Shengjie Lai Zhongjie Li Zhimin Liu Luzhao Feng Weizhong Yang School of Population Medicine and Public Health Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Department of management science and information system Faculty of Management and EconomicsKunming University of Science and TechnologyKunming 650504China WorldPop School of Geography and Environmental ScienceUniversity of SouthamptonSouthampton SO171BJUK The Third Affiliated Hospital of Kunming Medical University Kunming 650118China

Surveillance is an essential work on infectious diseases prevention and *** the pandemic occurred,the inadequacy of traditional surveillance was exposed,but it also provided a valuable opportunity to explore new surveillance *** study aimed to estimate the transmission dynamics and epidemic curve of severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)Omicron BF.7 in Beijing under the emergent situation using Baidu index and influenza-like illness(ILI)surveillance.A novel hybrid model(multiattention bidirectional gated recurrent unit(MABG)-susceptible-exposed-infected-removed(SEIR))was developed,which leveraged a deep learning algorithm(MABG)to scrutinize the past records of ILI occurrences and the Baidu index of diverse symptoms such as fever,pyrexia,cough,sore throat,anti-fever medicine,and runny *** considering the current Baidu index and the correlation between ILI cases and coronavirus disease 2019(COVID-19)cases,a transmission dynamics model(SEIR)was formulated to estimate the transmission dynamics and epidemic curve of SARS-Co *** the COVID-19 pandemic,when conventional surveillance measures have been suspended temporarily,cases of ILI can serve as a useful indicator for estimating the epidemiological trends of *** the specific case of Beijing,it has been ascertained that cumulative infection attack rate surpass 80.25%(95%confidence interval(95%CI):77.51%-82.99%)since December 17,2022,with the apex of the outbreak projected to transpire on December *** culmination of existing patients is expected to occur three days subsequent to this *** reproduction number(Rt)represents the average number of secondary infections generated from a single infected individual at a specific point in time during an epidemic,remained below 1 since December 17,*** traditional disease surveillance systems should be complemented with information from modern surveillance data such as online data sources with advanced techn

关键词： COVID-19 Epidemic curve Baidu search engine Influenza-like illness Deep learning Transmission dynamics model

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心源性猝死的流行病学研究进展

中华流行病学杂志 2015年第1期36卷 87-89页

作者：范国辉张林峰中国医学科学院阜外心血管病医院国家心血管中心社区防治部北京102308

心源性猝死（SCD）是一个多病因、多危险因素疾病,是65岁以下成年人最常见死因,对患者及家庭影响深远,成为重大公共健康问题[1].SCD也为院外心血管病死因之首,所占比例为60％[2].近年来随着医疗环境的改善,SCD预防和急救设备如埋藏式复... 详细信息

心源性猝死（SCD）是一个多病因、多危险因素疾病,是65岁以下成年人最常见死因,对患者及家庭影响深远,成为重大公共健康问题[1].SCD也为院外心血管病死因之首,所占比例为60％[2].近年来随着医疗环境的改善,SCD预防和急救设备如埋藏式复律除颤器（implantable cardioverter defibrillators,ICD）和自动体外除颤器（automated external defibrillators,AED）等的使用,使SCD的预防和管理取得显著进展.

关键词：心脏性猝死流行病学

Use of angiotensin-converting enzyme inhibitors and angiotensin Ⅱ receptor blockers in context of COVID-19 outbreak:a retrospective analysis

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Frontiers of Medicine 2020年第5期14卷 601-612页

作者： Jiuyang Xu Chaolin Huang guohui fan Zhibo Liu Lianhan Shang Fei Zhou Yeming Wang Jiapei Yu Luning Yang Ke Xie Zhisheng Huang Lixue Huang Xiaoying Gu Hui Li Yi Zhang Yimin Wang Frederick G.Hayden Peter W.Horby Bin Cao Chen Wang Department of Basic Medical Sciences Tsinghua University School of MedicineBeijing 100084China Department of Infectious Diseases Jinyintan HospitalWuhan 430030China Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineNational Clinical Research Center for Respiratory DiseasesChina-Japan Friendship HospitalBeijing 100029China Institute of Respiratory Medicine Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Institute of Clinical Medical Sciences China-Japan Friendship HospitalBeijing 100029China Beijing University of Chinese Medicine Beijing 100029China Department of Respiratory Medicine Capital Medical UniversityBeijing 100029China Graduate School of Peking Union Medical College Chinese Academy of Medical SciencesBeijing 100730China Department of Medicine University of Virginia School of MedicineCharlottesvilleVA 22904USA Centre for Tropical Medicine and Global Health University of OxfordOxford OX12JDUK Tsinghua University-Peking University Joint Center for Life Sciences Beijing 100084China Chinese Academy of Engineering Beijing 100088China

The possible effects of angiotensin-converting enzyme inhibitors(ACEIs)or angiotensin Ⅱ receptor blockers(ARBs)on COVID-19 disease severity have generated considerable *** performed a single-center,retrospective analysis of hospitalized adult COVID-19 patients in Wuhan,China,who had definite clinical outcome(dead or discharged)by February 15,*** on anti-hypertensive treatment with or without ACEI/ARB were compared on their clinical characteristics and *** medical records from 702 patients were *** the 101 patients with a history of hypertension and taking at least one anti-hypertensive medication,40 patients were receiving ACEI/ARB as part of their regimen,and 61 patients were on antihypertensive medication other than ACEI/*** observed no statistically significant differences in percentages of in-hospital mortality(28%vs.34%,P=0.46),ICU admission(20%vs.28%,P=0.37)or invasive mechanical ventilation(18%vs.26%,P=0.31)between patients with or without ACEI/ARB *** multivariable adjustment of age and gender did not provide evidence for a significant association between ACEI/ARB treatment and severe COVID-19 *** findings confirm the lack of an association between chronic receipt of reninangiotensin system antagonists and severe outcomes of *** should continue previous antihypertensive therapy until further evidence is available.

关键词： COVED-19 SARS-CoV-2 hypertension angiotensin-converting enzyme inhibitor angiotensinⅡreceptor blocker

Can patients with mild non-neoplastic lesions diagnosed at baseline screening be safely exempt from surveillance: evidence from multicenter community-based cohorts

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Science China Life Sciences 2025年第1期68卷 263-271页

作者： Siyi He Zhiyi Zhang guohui Song Zhenhai Wang Chunyun Dai Shipeng Yan Kun Jiang Bingbing Song He Li Maomao Cao Dianqin Sun fan Yang Xinxin Yan Shaoli Zhang Yi Teng Qianru Li Changfa Xia Wanqing Chen Office of Cancer Screening National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College Department of Gastroenterology Gansu Wuwei Tumor Hospital Cixian Cancer Institute Linzhou Cancer Hospital Center for Disease Control and Prevention of Sheyang County Department of Cancer Prevention and Control Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South University Luoshan Center for Disease Control and Prevention Office for Cancer Control and Research Affiliated Cancer Hospital of Harbin Medical University

Surveillance recommendations for gastric cancer（GC） in current guidelines focused on advanced precancerous lesions and were based on precise diagnosis of severity/extent of baseline lesions. We aimed to develop a less endoscopy-related equipment-dependent risk-stratification tool, and assessed whether mild-precursor-lesion patients can be safely exempt from surveillance. In the multicenter communitybased cohort, 75,051 participants receiving baseline endoscopy were enrolled during 2015–2017 and followed-up until 2021. Cumulative incidence rates（CIRs） of GC for precancerous-conditions were calculated by Kaplan-Meier method and compared by Log-rank tests. Mixedeffects Cox regression models were used to detect potential factors for progression towards GC. A risk score was calculated as counts of selected factors. An independent cohort, including 26,586 participants was used for external validation. During a median follow-up of 6.25 years, CIRs of GC were 0.302%, 0.436%, and 4.756% for normal group, non-neoplastic（atrophic gastritis/intestinal metaplasia） and neoplastic lesions（low-grade/high-grade dysplasia）, respectively(Ptrend<0.001). Four predictors, including male, ≥60 years, smoking, and limited vegetable consumption, were selected for risk-stratification. High-risk patients（≥3 risk factors） with non-neoplastic lesions showed higher GC risks（adjusted HR=7.73, 95%CI: 4.29–13.92）, and their four-year CIR reached the one-year CIR of neoplastic lesions. Further categorizing non-neoplastic lesions by histological grade, both patients with moderate-to-severe lesions（aHR=3.07, 95%CI: 1.67–5.64） and high-risk patients with mild lesions（aHR=7.29, 95%CI: 3.58–14.86） showed higher risks. Consistent trends were observed in validation cohort. High-risk mild-precursor-lesion patients should receive surveillance within 3–5 years after baseline screening. Our study provides evidence on supplementing current guideline recommendations.

关键词： stomach neoplasms precancerous conditions cancer screening cumulative incidence risk stratification

解析“BOBO族”及其多元混合家居艺术风格

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家具与室内装饰 2007年第10期14卷 88-89页

作者：范国辉河南工业职业技术学院河南南阳473009

本文详细介绍了"BOBO族"的生活理念,认真剖析了"BOBO族"的多元混合家居艺术风格,并将其与当前的家居艺术潮流进行了比较分析。

关键词：波波族家居艺术多元混合风格潮流

“高分北斗+智慧农业”应用领域高职生的创业路径研究

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创新创业理论研究与实践 2020年第2期3卷 196-198页

作者：范国辉河南工业职业技术学院河南南阳473000

研究高职生在"高分北斗+智慧农业"应用领域的创业路径。从行业背景、应用前景、现状分析、适合切入的创业项目、创业路径规划、创业路径实施策略6个层面进行了详细的论述。最后在创业动机、创业角色、创业地域、创业资源、经营模式5个方... 详细信息

研究高职生在"高分北斗+智慧农业"应用领域的创业路径。从行业背景、应用前景、现状分析、适合切入的创业项目、创业路径规划、创业路径实施策略6个层面进行了详细的论述。最后在创业动机、创业角色、创业地域、创业资源、经营模式5个方面,给出高职生在"高分北斗+智慧农业"应用领域的创业路径线路图。

关键词：高分遥感北斗信息智慧农业创业路径

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传染病智慧化症状监测的进展与挑战

中华流行病学杂志 2023年第9期44卷 1338-1343页

作者：范国辉张婷赖圣杰冯录召杨维中中国医学科学院北京协和医学院群医学及公共卫生学院北京100730 呼吸和共病全国重点实验室北京100730 病原体感染防控教育部重点实验室(北京协和医学院) 北京100730 英国南安普顿大学地理与环境科学学院南安普顿SO171BJ

智慧化症状监测是我国传染病智慧化预警多点触发和多渠道预警体系的重要组成部分,是传统症状监测在新技术发展下的必然路径。智慧化症状监测不仅包括医院就诊患者的大量医疗数据,还囊括未在医院就诊、海量的非医疗数据。然而,发展的同... 详细信息

智慧化症状监测是我国传染病智慧化预警多点触发和多渠道预警体系的重要组成部分,是传统症状监测在新技术发展下的必然路径。智慧化症状监测不仅包括医院就诊患者的大量医疗数据,还囊括未在医院就诊、海量的非医疗数据。然而,发展的同时也迎来了挑战,如信息爆炸、成本-效益问题以及数据共享、数据安全和隐私问题。本文通过对智慧化症状监测相关概念发展的思考和总结,为传染病智慧化预警方法与技术的发展提供参考,为我国和全球传染病防控提供新思路。

关键词：智慧化症状监测传染病防控进展挑战

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肾功能不全与静脉血栓栓塞症

中华结核和呼吸杂志 2022年第2期45卷 204-208页

作者：王丁一范国辉吴司南翟振国中日友好医院临床医学研究所国家呼吸医学中心中国医学科学院呼吸病学研究院北京100029 中日友好医院呼吸中心国家呼吸医学中心中国医学科学院呼吸病学研究院北京100029

静脉血栓栓塞症(VTE)是临床常见、多发病。肾功能不全发生率高而病程隐匿,患者常存在凝血系统功能异常。近年来研究发现,肾功能不全患者VTE发病率高,同时合并肾功能不全或慢性肾脏病的患者VTE发病率以及不良结局发生率均升高,提示肾功... 详细信息

静脉血栓栓塞症(VTE)是临床常见、多发病。肾功能不全发生率高而病程隐匿,患者常存在凝血系统功能异常。近年来研究发现,肾功能不全患者VTE发病率高,同时合并肾功能不全或慢性肾脏病的患者VTE发病率以及不良结局发生率均升高,提示肾功能不全是影响VTE预后的重要因素。肾功能情况亦是影响VTE诊断手段选择和药物剂量调整的重要因素。本文拟就肾功能不全与VTE的发病、机制、转归以及对诊治的影响等方面,结合国内外研究的最新进展进行综述,为VTE临床防治提供线索。

关键词：静脉血栓栓塞症肾功能不全慢性肾脏病功能异常凝血系统肾功能情况不良结局药物剂量

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实用节约健康型家装设计的探索

家具与室内装饰 2009年第6期16卷 26-27页

作者：范国辉王延丽河南工业职业技术学院河南南阳473009

本文详细介绍了实用节约健康型家装设计的基本理念,并以实际工程为载体详细阐述了该理念在实践中的应用。

关键词：实用节约健康家装设计