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An Indirect ELISA of Classical Swine Fever Virus Based on Quadruple Antigenic Epitope Peptide Expressed in ***

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Virologica Sinica 2010年第1期25卷 71-76页

作者： guo-zhen lin fu-ying zheng ji-zhang zhou xiao-an cao xiao-wei GONG Guang-hua WANG chang-qing qiu Key Laboratories of Grazing Animal Diseases and Animal Virology Ministry of Agriculture Lanzhou Veterinary Research Institute Chinese Academy of Agricultural Sciences Lanzhou 730046 China State Key Laboratory of Veterinao Etiological Biology Lanzhou Veterinary Research Institute Chinese Academy of Agricultural Sciences Lanzhou 730046 China

In this study,a synthesized quadruple antigenic epitope gene region of the classical swine fever virus (CSFV)E2 glycoprotein was expressed in *** to a obtain target *** target protein was used as a coating antigen to establish an indirect ELISA for specifically detecting anti-CSFV antibodies in serum samples from *** P/N cut-off value of this assay was 1.92 by receiver operating characteristic curve(ROC)analysis based on 30 negative sera and 80 positive *** test gave 97.5%sensitivity and 96.7%specificity compared with the indirect hemagglutination(IHA)*** inter-assay and intra-assay coefficients of variation (CVs)for 16 sera were both≤6.8%.No cross-reactivity between the coating antigen and anti-bovine viral diarrhoea virus(BVDV)antibodies was observed.

关键词： Antigenic epitope Bovine viral diarrhoea virus (BVDV) Classical swine fever virus (CSFV) Expression Indirect ELISA

nested-PCR试剂盒检测牛精液中的布鲁氏菌DNA

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中国人兽共患病学报 2008年第2期24卷 137-139页

作者：曹小安邱昌庆周继章蔺国珍郑福英甘肃农业大学动物医学院兰州730070 中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室兰州730046

目的布鲁氏菌是兼性细胞内寄生菌,能够在吞噬细胞内长期存活并繁殖,引起家畜流产和人的波浪热。根据病原性和感染宿主的不同将布鲁氏菌分为六个种,能否快速、有效地从各种病料中检出布鲁氏菌,对及时控制布鲁氏菌在家畜中的传播和预防对... 详细信息

目的布鲁氏菌是兼性细胞内寄生菌,能够在吞噬细胞内长期存活并繁殖,引起家畜流产和人的波浪热。根据病原性和感染宿主的不同将布鲁氏菌分为六个种,能否快速、有效地从各种病料中检出布鲁氏菌,对及时控制布鲁氏菌在家畜中的传播和预防对人的感染十分重要。方法2006年6月,宁夏某公司奶牛场工作人员送检3份奶牛冻干精液,用巢式PCR检测出其中的2份为布鲁氏菌感染阳性,这年8月,重复取这2头种公牛的冻精、鲜精复查。结果用本方法检测全部为布鲁氏菌感染阳性。结论这是国内首次用巢式聚合酶链反应(nested-PCR)试剂盒从送检的牛精液中检出了布鲁氏菌DNA片段。

关键词：布鲁氏菌 nested-PCR 牛精液检测

The Chinese Society of Clinical Oncology(CSCO):Clinical guidelines for the diagnosis and treatment of gastric cancer,2021

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Cancer Communications 2021年第8期41卷 747-795页

作者： Feng-Hua Wang xiao-Tian zhang Yuan-Fang Li Lei Tang Xiu-Juan Qu jie-Er ying Jun zhang ling-Yu Sun Rong-Bo lin Hong qiu chang Wang Miao-zhen qiu Mu-Yan Cai QiWu Hao Liu Wen-Long Guan Ai-Ping zhou Yu-jing zhang Tian-Shu Liu Feng Bi Xiang-lin Yuan Sheng-Xiang Rao Yan Xin Wei-Qi Sheng Hui-Mian Xu guo-Xin Li jia-fu ji Zhi-Wei zhou Han Liang Yan-Qiao zhang jing jin lin Shen jin Li Rui-Hua Xu Department of Medical Oncology State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Gastrointestinal Oncology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer Hospital and InstituteBeijing 100142P.R.China Department of Gastric Surgery State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Radiology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer Hospital and InstituteBeijing 100142P.R.China Department of Medical Oncology The First Hospital of China Medical UniversityShenyangLiaoning 110001P.R.China Department of Medical Oncology Zhejiang Cancer HospitalHangzhouZhejiang 310006P.R.China Department of Medical Oncology Ruijin HospitalShanghai Jiaotong University School of MedicineShanghai 200025P.R.China Department of Surgical Oncology The Fourth Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150001P.R.China Department of Medical Oncology Fujian Cancer HospitalFuzhouFujian 350000P.R.China Department of Medical Oncology Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubei 430030P.R.China Cancer Center of The First Hospital of jilin University ChangchunJilin 130021P.R.China Department of Pathology State Key Laboratory of Oncology in South ChinaCollaborative Innovation Center of Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Endoscopy Center Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer Hospital and InstituteBeijing 100142P.R.China Department of General Surgery Nanfang HospitalSouthern Medical UniversityGuangzhouGuan

There exist differences in the epidemiological characteristics,clinicopathological features,tumor biological characteristics,treatment patterns,and drug selections between gastric cancer patients from the Eastern and Western *** Chinese Society of Clinical Oncology(CSCO)has organized a panel of senior experts specializing in all sub-specialties of gastric cancer to compile a clinical guideline for the diagnosis and treatment of gastric cancer since 2016 and renews it *** into account regional differences,giving full consideration to the accessibility of diagnosis and treatment resources,these experts have conducted expert consensus judgment on relevant evidence and made various grades of recommendations for the clinical diagnosis and treatment of gastric cancer to reflect the value of cancer treatment and meeting health economic indexes in *** 2021 CSCO Clinical Practice Guidelines for Gastric Cancer covers the diagnosis,treatment,follow-up,and screening of gastric *** on the 2020 version of the CSCO Chinese Gastric Cancer guidelines,this updated guideline integrates the results ofmajor clinical studies from China and overseas for the past year,focused on the inclusion of research data from the Chinese population for more personalized and clinically relevant *** the comprehensive treatment of non-metastatic gastric cancer,attentions were paid to neoadjuvant *** value of perioperative chemotherapy is gradually becoming clearer and its recommendation level has been *** the comprehensive treatment of metastatic gastric cancer,recommendations for immunotherapy were included,and immune checkpoint inhibitors fromthird-line to the first-line of treatment for different patient groups with detailed notes are provided.

关键词： adjuvant chemotherapy Chinese Society of Clinical Oncology(CSCO) diagnosis gastric cancer immunotherapy neoadjuvant radiotherapy surgery targeted therapy

The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of gastric cancer, 2023

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Cancer Communications 2024年第1期44卷 127-172页

作者： Feng-Hua Wang xiao-Tian zhang Lei Tang Qi Wu Mu-Yan Cai Yuan-Fang Li Xiu-Juan Qu Hong qiu Yu-jing zhang jie-Er ying Jun zhang ling-Yu Sun Rong-Bo lin chang Wang Hao Liu Miao-zhen qiu Wen-Long Guan Sheng-Xiang Rao jia-fu ji Yan Xin Wei-Qi Sheng Hui-Mian Xu Zhi-Wei zhou Ai-Ping zhou jing jin Xiang-lin Yuan Feng Bi Tian-Shu Liu Han Liang Yan-Qiao zhang guo-Xin Li Jun Liang Bao-Rui Liu lin Shen jin Li Rui-Hua Xu Department of Medical Oncology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdongP.R.China Department of Gastrointestinal Oncology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer HospitalBeijingP.R.China Department of Radiology Peking University Cancer HospitalBeijingP.R.China Department of Endoscopy Center Peking University Cancer HospitalBeijingP.R.China Department of Pathology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center of Cancer MedicineGuangzhouGuangdongP.R.China Department of Gastric Surgery Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdongP.R.China Department of Medical Oncology The First Hospital of China Medical UniversityShenyangLiaoningP.R.China Department of Medical Oncology Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubeiP.R.China Department of Radiotherapy Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangzhouGuangdongP.R.China Department of Medical Oncology Zhejiang Cancer HospitalHangzhouZhejiangP.R.China Department of Medical Oncology Ruijin HospitalShanghai Jiaotong University School of MedicineShanghaiP.R.China Department of Surgical Oncology The Fourth Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiangP.R.China Department of Medical Oncology Fujian Cancer HospitalFuzhouFujianP.R.China Tumor Center The First Hospital of Jilin UniversityChangchunJilinP.R.China Department of General Surgery Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongP.R.China Department of Radiology Zhongshan HospitalFudan UniversityShanghaiP.R.China Department of

The 2023 update of the Chinese Society of Clinical Oncology(CSCO)Clini-cal Guidelines for Gastric Cancer focuses on standardizing cancer diagnosis and treatment in China,reflecting the latest advancements in evidence-based medicine,healthcare resource availability,and precision *** updates address the differences in epidemiological characteristics,clinicopatho-logical features,tumor biology,treatment patterns,and drug selections between Eastern and Western gastric cancer *** revisions include a structured template for imaging diagnosis reports,updated standards for molecular marker testing in pathological diagnosis,and an elevated recommendation for neoadju-vant chemotherapy in stage III gastric *** advanced metastatic gastric cancer,the guidelines introduce new recommendations for immunotherapy,anti-angiogenic therapy and targeted drugs,along with updated management strategies for human epidermal growth factor receptor 2(HER2)-positive and deficient DNA mismatch repair(dMMR)/microsatellite instability-high(MSI-H)***,the guidelines offer detailed screening recommendations for hereditary gastric cancer and an appendix listing drug treatment regimens for various stages of gastric *** 2023 CSCO Clinical Guidelines for Gastric Cancer updates are based on both Chinese and international clinical research and expert consensus to enhance their applicability and relevance in clinical practice,particularly in the heterogeneous healthcare landscape of China,while maintaining a commitment to scientific rigor,impartiality,and timely revisions.

关键词： Chinese Society of Clinical Oncology(CSCO) gastric cancer diagnosis surgery neoadjuvant adjuvant radiotherapy chemotherapy targeted therapy immunotherapy

流产布鲁氏菌BCSP31基因在大肠杆菌中的可溶性高效表达

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吉林农业大学学报 2007年第6期29卷 683-686页

作者：曹小安邱昌庆周继章蔺国珍中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室

设计1对引物,突变除去布鲁氏菌BCSP31(细胞表面蛋白31)基因的N端信号肽氨基酸序列,经NotⅠ和EcoRⅠ酶切后与相同处理的表达载体pGEX-4T-1连接,转化BL21(DE3)感受态细胞。酶切及PCR扩增鉴定,获得阳性克隆,测序证明其阅读框完全正确。用I... 详细信息

设计1对引物,突变除去布鲁氏菌BCSP31(细胞表面蛋白31)基因的N端信号肽氨基酸序列,经NotⅠ和EcoRⅠ酶切后与相同处理的表达载体pGEX-4T-1连接,转化BL21(DE3)感受态细胞。酶切及PCR扩增鉴定,获得阳性克隆,测序证明其阅读框完全正确。用IPTG诱导表达构建成功的阳性克隆,对产物进行SDS-PAGE和Western-blotting检测,发现表达产物出现预期分子量57 kD的融合蛋白,该蛋白能与牛流产布鲁氏菌阳性血清发生反应,进一步证明目的蛋白主要以可溶性形式存在,表达量约占总蛋白的40%,应用GST琼脂糖凝胶FF纯化可得到纯度较高的表达产物。

关键词：流产布鲁氏菌 BCSP31基因克隆可溶性表达

10B-doped MCP detector developed for neutron resonance imaging at Back-n white neutron source

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Nuclear Science and Techniques 2024年第8期35卷 58-68页

作者： Qiang Li Li‑jiao Wang jing‑Yu Tang Xiang‑Biao qiu zhen Chen Mao‑Yuan Zhao chang‑Jun Ning Kai Pan Wei Xu Tao Li Su‑Peng Lu Han Yi Rui‑Rui Fan chang‑qing Feng Rong zhang xiao‑Yang Sun Qi An Hao‑Fan Bai jiang‑Bo Bai jie Bao Ping cao Qi‑Ping Chen Yong‑Hao Chen Zeng‑Qi Cui An‑Chuan Fan Fan‑zhen Feng Min‑Hao Gu chang‑Cai Han Zi‑jie Han guo‑Zhu He Yong‑Cheng He Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei jiang Zhi‑jie jiang zheng‑Yao jin ling Kang Bo Li Gong Li xiao Li Yang Li jie Liu Rong Liu Shu‑Bin Liu Yi‑Na Liu Guang‑Yuan Luan jie Ren Zhi‑zhou Ren Xi‑Chao Ruan Zhao‑Hui Song Kang Sun Zhi‑Xin Tan Sheng‑Da Tang jin‑Cheng Wang Peng‑Cheng Wang Zhao‑Hui Wang Zhong‑Wei Wen xiao‑Guang Wu Xuan Wu Cong Xia Yong‑ji Yu guo‑Hui zhang Hang‑chang zhang lin‑Hao zhang Qi‑Wei zhang Xian‑Peng zhang Yu‑Liang zhang Yue zhang Zhi‑Yong zhang Zhi‑Hao zhou Ke‑Jun Zhu Chong Zou Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake future School Dongguan 523808China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China North Night Vision Science and Technology(Nanjing)Research Institute Co.Ltd Nanjing 211106China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China China Academy of Engineering Physics Institute of Nuclear Physics and ChemistryMianyang 621900China USTC archaeometry lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China China Shipbuilding Trading Co. LtdBeijing 100044China

Neutron resonance imaging(NRI)has recently emerged as an appealing technique for neutron *** complexity surpasses that of conventional transmission imaging,as it requires a high demand for both a neutron source and ***,the progression of NRI technology has been sluggish since its inception in the 1980s,particularly considering the limited studies analyzing the neutron energy range above *** white neutron source(Back-n)at the China Spallation Neutron Source(CSNS)provides favorable beam conditions for the development of the NRI technique over a wide neutron energy range from eV to ***-sensitive microchannel plates(MCP)have emerged as a cutting-edge tool in the field of neutron detection owing to their high temporal and spatial resolutions,high detection efficiency,and low *** this study,we report the development of a 10B-doped MCP detector,along with its associated electronics,data processing system,and NRI experiments at the *** heavy elements such as gold,silver,tungsten,and indium can be easily identified in the transmission images by their characteristic resonance peaks in the 1–100 eV energy range;the more difficult medium-weight elements such as iron,copper,and aluminum with resonance peaks in the 1–100 keV energy range can also be *** particular,results in the neutron energy range of dozens of keV(Aluminum)are reported here for the first time.

关键词： Neutron resonance imaging 10B doped MCP detector White neutron source Sample nuclide identification

鸡源鹦鹉热衣原体MOMP基因重组腺病毒的稳定性及SPF雏鸡免疫试验

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第四军医大学学报 2007年第2期28卷 100-103页

作者：周继章邱昌庆张小英蔺国珍曹小安张琳程淑敏中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室农业部畜禽病毒学重点开发实验室甘肃兰州730046 兰州市动物检疫站甘肃兰州730050

目的:检测重组腺病毒质粒在HEK293细胞中的稳定性;重组腺病毒是否与减蛋综合征阳性血清发生中和反应,以及用重组腺病毒免疫SPF小鸡是否产生保护.方法:将重组腺病毒质粒在HEK293细胞中连续传代,并用PCR法检测目的基因;用减蛋综合征阳性... 详细信息

目的:检测重组腺病毒质粒在HEK293细胞中的稳定性;重组腺病毒是否与减蛋综合征阳性血清发生中和反应,以及用重组腺病毒免疫SPF小鸡是否产生保护.方法:将重组腺病毒质粒在HEK293细胞中连续传代,并用PCR法检测目的基因;用减蛋综合征阳性血清在体外中和重组腺病毒,接种HEK293细胞;用重组腺病毒免疫SPF小鸡,然后用CpL菌株攻击.结果:重组腺病毒质粒在HEK293细胞中连续传代后,仍然用PCR检测能检测出目的基因;重组腺病毒与减蛋综合征阳性血清之间无交叉反应;用重组腺病毒免疫SPF鸡,用CpL菌株攻击,90%的小鸡获得了保护.结论:重组腺病毒质粒在HEK293细胞中能稳定传代;重组腺病毒不受减蛋综合征阳性血清的影响;用重组腺病毒免疫SPF小鸡,能够获得保护.

关键词：衣原体鹦鹉MOMP 重组遗传腺病毒科中和试验雏鸡免疫

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乳牛衣原体病灭活疫苗效检小鼠模型的建立

中国兽医科学 2008年第2期38卷 120-122页

作者：邱昌庆周继章程淑敏曹小安蔺国珍中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室甘肃兰州730046

为了解决以本动物效检乳牛衣原体病灭活疫苗成本高的问题,用11批乳牛衣原体病灭活疫苗做乳牛效力试验时同步做小鼠效力试验,除第3批次疫苗的本动物效检结果与小鼠效检结果略有差异外,其他批次疫苗的效检结果均一致。结果表明,用小鼠做... 详细信息

为了解决以本动物效检乳牛衣原体病灭活疫苗成本高的问题,用11批乳牛衣原体病灭活疫苗做乳牛效力试验时同步做小鼠效力试验,除第3批次疫苗的本动物效检结果与小鼠效检结果略有差异外,其他批次疫苗的效检结果均一致。结果表明,用小鼠做牛衣原体灭活疫苗的效检动物模型是可行的。

关键词：乳牛衣原体病灭活疫苗效力试验小鼠模型

Study of the response of 10B-doped MCP to wide-energy range neutrons from eV to MeV

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Nuclear Science and Techniques 2024年第8期35卷 132-141页

作者： Qiang Li Li‑jiao Wang Xiang‑Biao qiu jing‑Wen Li Wei Xu Tao Li Ze‑Bin lin chang‑Jun Ning Yong‑Hao Chen Rui‑Rui Fan Kang Sun jing‑Yu Tang Rong zhang Han‑Tao jing Bo Mei Qi An Hao‑Fan Bai jiang‑Bo Bai jie Bao Ping cao Qi‑Ping Chen zhen Chen Zeng‑Qi Cui An‑Chuan Fan chang‑qing Feng Fan‑zhen Feng Ke‑qing Gao Min‑Hao Gu chang‑Cai Han Zi‑jie Han guo‑Zhu He Yong‑Cheng He Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei‑Hua jia Hao‑Yu jiang Wei jiang Zhi‑jie jiang zheng‑Yao jin ling Kang Bo Li Chao Li Gong Li jia‑Wen Li xiao Li Yang Li jie Liu Rong Liu Shu‑Bin Liu Guang‑Yuan Luan Bin‑Bin Qi jie Ren Zhi‑zhou Ren Xi‑Chao Ruan Zhao‑Hui Song Zhi‑Xin Tan Sheng‑Da Tang Peng‑Cheng Wang Zhao‑Hui Wang Zhong‑Wei Wen xiao‑Guang Wu Xuan Wu Li‑Kun Xie Yi‑Wei Yang Han Yi Yong‑ji Yu guo‑Hui zhang lin‑Hao zhang Mo‑Han zhang Qi‑Wei zhang Xian‑Peng zhang Yu‑Liang zhang Yue zhang Zhi‑Yong zhang Mao‑Yuan Zhao Lu‑Ping zhou Zhi‑Hao zhou Ke‑Jun Zhu Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake future School Dongguan 523808China North Night Vision Science&Technology(Nanjing)Research Institute Co.Ltd. Nanjing 211106China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Neutron-sensitive microchannel plates(nMCPs)have applications in neutron detection,including energy spectrum measurements,neutron-induced cross sections,and neutron imaging.10B-doped MCPs(B-MCPs)have attracted significant attention owing to their potential for exhibiting a high neutron detection efficiency over a large neutron energy *** spatial and temporal resolutions are useful for neutron energy-resolved ***,their practical applications still face many technical *** this study,a B-MCP with 10 mol%10B was tested for its response to wide-energy neutrons from eV to MeV at the Back-n white neutron source at the China Spallation Neutron *** neutron detection efficiency was calibrated at 1 eV,which is approximately 300 times that of an ordinary MCP and indicates the success of 10 B *** factors that caused the reduction in the detection efficiency were simulated and *** neutron energy spectrum obtained using B-MCP was compared with that obtained by other measurement methods,and showed very good consistency for neutron energies below tens of *** response is more complicated at higher neutron energy,at which point the elastic and nonelastic reactions of all nuclides of B-MCP gradually become *** is beneficial for the detection of neutrons,as it compensates for the detection efficiency of B-MCP for high-energy neutrons.

关键词： Neutron radiation image 10B-doped MCP Neutron response Wide-energy range neutrons