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Coupled CFD-DEM Numerical Simulation of the Interaction of a Flow-Transported Rag with a Solid Cylinder

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Fluid Dynamics & Materials Processing 2024年第7期20卷 1593-1609页

作者： Yun Ren Lianzheng Zhao Xiaofan mo Shuihua Zheng Youdong Yang Zhijiang College Zhejiang University of TechnologyShaoxing312030China College of Mechanical Engineering Zhejiang University of TechnologyHangzhou310032China

A coupled Computational Fluid Dynamics-Discrete Element Method(CFD-DEM)approach is used to calculate the interaction of a flexible rag transported by a fluid current with a fixed solid *** specifically a hybrid Eulerian-Lagrangian approach is used with the rag being modeled as a set of interconnected *** influence of various parameters is considered,namely the inlet velocity(1.5,2.0,and 2.5 m/s,respectively),the angle formed by the initially straight rag with the flow direction(45°,60°and 90°,respectively),and the inlet position(90,100,and 110 mm,respectively).The results show that the flow rate has a significant impact on the permeability of the *** higher the flow rate,the higher the permeability and the rag speed *** angle has a minor effect on rag permeability,with 45°being the most favorable angle for *** inlet position has a small impact on rag permeability,while reducing the initial distance between the rag an the cylinder makes it easier for rags to pass through.

关键词： Rag flow around cylinder flow characteristics numerical simulation

野外-城市界域森林火险时空演变趋势及火险等级划分

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生态学报 2024年第14期44卷 6232-6242页

作者：莫凡郭慧裴顺祥吴迪吴莎辛学兵中国林业科学研究院华北林业实验中心北京九龙山暖温带森林国家长期科研基地北京102300

野外-城市界域(WUI)人类活动密集,火灾风险极大,在该区域进行森林火险的合理性评价和时空演变趋势分析,对保护区域生态环境和社会经济可持续发展具有重要意义。以北京近郊九龙山林场为研究对象,基于相关火险驱动因子指标数据,运用层次... 详细信息

野外-城市界域(WUI)人类活动密集,火灾风险极大,在该区域进行森林火险的合理性评价和时空演变趋势分析,对保护区域生态环境和社会经济可持续发展具有重要意义。以北京近郊九龙山林场为研究对象,基于相关火险驱动因子指标数据,运用层次分析法评估研究区2004、2009、2014、2019年森林火险指数,通过Theil-Sen Median趋势分析、全局莫兰指数和局部莫兰指数分析探究森林火险指数的变化趋势及空间聚集性,并基于历史火情数据和地理探测器模型验证火险区划的合理性和准确性。结果表明:(1)九龙山林场内火险指数整体的集聚特征变化较大,61.58%的区域火险指数不显著增加,5.62%的区域微显著增加,32.80%区域为不显著减少和微显著减少。(2)森林火险指数空间上呈正相关,森林火险高值聚集区域分布于东部低海拔地区,在研究时间段内面积减少4.89%,低值聚集区域分布于西部高海拔地区,面积减少2.19%。(3)森林火险区划结果显示,九龙山林场森林高火险区域面积占比最小,主要分布于研究区中部,由于人类活动的影响,高火险区覆盖范围扩大。(4)区划合理性验证结果显示,研究区森林火险等级空间分异性较好,与实际火点分布具有高度一致性。研究结果较好的反应了研究区森林火险时空格局变化,为九龙山林场进一步合理规划防火设施布局,加强火险管控力度,完善防火应急能力奠定数据基础,提示管理部门应加强防火宣传,以最大限度发挥九龙山的生态环境效益,保障林区周边人民生命财产安全。

关键词：森林火险指数空间相关性时空演变趋势火险区划合理性评价

Impact of oxaliplatin and trastuzumab combination therapy on tumor markers and T lymphocyte subsets for advanced gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第9期16卷 3905-3912页

作者： Cheng-Wan Zheng Yun-mo Yang Hui Yang Department of Thyroid Surgery The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

BACKGROUND Advanced gastric cancer(AGC)remains a challenging malignancy with poor *** combination of oxaliplatin and trastuzumab has shown promising results in AGC *** study aimed to investigate the effects of oxaliplatin and trastuzumab combination therapy on serum tumor markers and T lymphocyte subsets in patients with AGC and to explore their potential as predictive biomarkers for treatment *** To investigate the impact of oxaliplatin and trastuzumab combination therapy on serum markers and T cell subsets in patients with *** This prospective study enrolled 60 patients with *** patients received oxaliplatin(130 mg/m^(2),every 3 weeks)and trastuzumab(8 mg/kg loading dose,followed by 6 mg/kg every 3 weeks)for six *** carcinoembryonic antigen(CEA),cancer antigen 19-9(CA19-9),and cancer antigen 72-4(CA72-4)were measured before and after treatment.T-lymphocyte subsets,including CD3+,CD4+,CD8+,and CD4+/CD8+ratios,were also *** clinical response was assessed using the Response Evaluation Criteria in Solid Tumors version *** After six cycles of treatment,the CEA,CA19-9,and CA72-4 serum levels significantly decreased compared to baseline levels(Pmor markers(≥50%reduction)and a higher increase in CD4+/CD8+ratio(≥1.5-fold)showed better clinical response rates(Pmor marker levels and modulated T lymphocyte subsets in patients with *** therapy not only has a direct antitumor effect,but also enhances the immune response in patients with *** tumor markers and T lymphocyte subsets may serve as potential predictive biomarkers for treatment respon

关键词： Advanced gastric cancer Oxaliplatin Trastuzumab Serum tumor markers T lymphocyte subsets Predictive biomarkers

Refined acoustic holography via nonlocal metasurfaces

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Science China(Physics,Mechanics & Astronomy) 2024年第7期67卷 113-123页

作者： Shuhuan Xie Hongyu Ma Junmei Cao Fangshuo mo Qian Cheng Yong Li Tong Hao Institute of Acoustics School of Physics Science and EngineeringTongji UniversityShanghai 200092China Center for Spatial Information Science and Sustainable Development Applications Tongji UniversityShanghai 200092China College of Surveying and Geo-Informatics Tongji UniversityShanghai 200092China

Holography can provide the desired wavefront phase and/or amplitude for imaging,particle manipulation,bacteria trapping,and cell patterning in optics and ***,previous work on acoustic holography is mostly based on local design optimization,either using active control of the sound source or relying on the structural design to provide the desired *** precise control over the acoustic field remains a significant ***,we realize refined single-plane symmetric binary amplitude,asymmetric intensity gradient amplitude,and bi-objective hologram through the non-local holographic imaging theory that considers the acoustic coupling of structural units in *** taking into account the self-radiation and mutual radiation between many small units on a plate of well-designed thickness,as well as the transmission through the plate's apertures,we can effectively regulate the sound field behind the *** demonstrate the effectiveness of our approach through numerical simulations and experiments,showcasing a circle,a black hole,and a bi-objective with a circle and a square ***,the acoustic black hole hologram precisely reconstructs the intensity gradient distribution at two bright *** non-local holographic imaging theory is valuable for the fine-intensity regulation of the sound field and is expected to be applied in ultrasound diagnosis and treatment,medical imaging,and other fields.

关键词： acoustic holograms non-local interactions fine intensity modulation acoustic metasurfaces

The effect of friction block hole configurations on the brake tribological performance of high-speed trains

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Friction 2024年第10期12卷 2241-2258页

作者： Yuanke WU Wei CHEN Youguang ZHU Zaiyu XIANG Honghua QIAN Jiliang mo Zhongrong ZHOU Tribology Research Institute School of Mechanical EngineeringSouthwest Jiaotong UniversityChengdu 610031China China Railway Engineering Equipment Group Co. Ltd.Zhengzhou 450016China

Three triangular friction block configurations are commonly employed in high-speed train brake systems,namely,unperforated,perforated configuration with one circular hole,and perforated with three circular *** this study,we adopted these friction block types to investigate the effect of perforated friction block configurations on the brake performance of high-speed trains based on a self-developed brake test *** results indicate the significant impact of the number of the holes on the wear behavior,temperature distribution,and vibration characteristics of the brake *** friction surface of the unperforated block is covered by wear debris,while the perforated blocks produce less wear ***,the one-hole block exhibits a more uniform temperature distribution and better vibration behavior than that with three *** friction brake is a dynamic process,during which separation and attachment between the pad and disc alternatively occur,and the perforated structure on the friction block can both trap and expel the wear debris.

关键词： high-speed train block brake performance wear debris flow

Precise immobilization of metal single atoms into a porphyrinic metal-organic framework for an efficient alkene hydrosilylation

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Nano Research 2024年第7期17卷 5914-5921页

作者： Chun-Ying Chen Qi-Jie mo Fu-Zhen Li Hai-Li Song Li Zhang moE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional MaterialsSchool of ChemistrySun Yat-Sen UniversityGuangzhou 510006China

Alkene hydrosilylation is one of the most concise and atom-economical methods to synthesize organosilicon ***,we reported the precise immobilization of metal single atoms(M-SAs;M=Ru,Rh,Ir,Pd,Pt,and Au)into a porphyrinic metalorganic framework(moF)of PCN-222(PCN=porous coordination network),and then applied the resultant moF composites of M-SAs@PCN-222 to alkene *** solvent-free conditions,Pt-SAs@PCN-222 displayed an especially high catalytic efficiency with the turnover frequency up to 119 s−1 and the maximum turnover number of 906,250 at room *** and theoretical studies revealed that there existed strong interactions between Pt-SAs@PCN-222 and the substrates,which helped to condense the substrates in the cavities of the porous *** density functional theory calculations and molecular dynamics simulations disclosed that PCN-222 could transfer electrons to Pt-SAs to enhance the silane oxidative addition and drive the reaction to proceed smoothly via Chalk–Harrod pathway.

关键词： alkene hydrosilylation single atom catalysts metal-organic frameworks precision chemistry synergistic catalysis

An efficient labeled memory system for learned indexes

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Fundamental Research 2024年第3期4卷 651-659页

作者： Yuxuan mo Jingnan Jia Pengfei Li Yu Hua Huazhong University of Science and Technology Wuhan 430074China

The appearance and wide use of memory hardware bring significant changes to the conventional vertical memory hierarchy that fails to handle contentions for shared hardware resources and expensive data *** deal with these problems,existing schemes have to rely on inefficient scheduling strategies that also cause extra temporal,spatial and bandwidth *** on the insights that the shared hardware resources trend to be uniformly and hierarchically offered to the requests for co-located applications in memory systems,we present an efficient abstraction of memory hierarchies,called Label,which is used to establish the connection between the application layer and underlying hardware *** on labels,our paper proposes LaMem,a labeled,resource-isolated and cross-tiered memory system by leveraging the way-based partitioning technique for shared resources to guarantee QoS demands of applications,while supporting fast and low-overhead cache repartitioning ***,we customize LaMem for the learned index that fundamentally replaces storage structures with computation models as a case study to verify the applicability of *** results demonstrate the efficiency and efficacy of LaMem.

关键词： Heterogeneous memory system Cache hierarchy Data movement Resource contention Learned index

Influence of Mass Ratio of Resin and Stabilizer on Mechanical Properties of mo Fiber-reinforced Granite Polymer Composite

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Journal of Wuhan University of Technology(Materials Science) 2024年第4期39卷 912-920页

作者：张超任秀华 BA Dongzhe ZHANG Jianhua LI Jianyong guo Mengnan GAO Yinghao WANG Guixin LI Jiayang School of Mechanical and Electronic Engineering Shandong Jianzhu UniversityJinan 250101China Key Laboratory of High Efficiency and Clean Mechanical Manufacture Ministry of Education of ChinaSchool of Mechanical EngineeringShandong UniversityJinan 250061China

Because inferior mechanical strength of granite polymer composite(GPC)has become the main drawback limiting its application and popularization,mo fibers were added into(GPC)to improve its mechanical *** properties of matrix materials with different mass ratio of resin and stabilizer(MRRS)were investigated *** influences of MRRS on interface bonding strength of mo fiber-matrix,wettability and mechanical strength of GPC were discussed,respectively,and the theoretical calculation result of MRRS k was obtained,with the optimal value of k=*** k=4,tensile strength,tensile strain and fracture stress of the cured resin achieve the maximum *** for k=7,the corresponding values reach the *** the increase of MRRS k,surface free energy of the cured resin first increases and then decreases,while contact angles between mo sample and matrix have displayed the opposite *** of resin to mo fiber is the best at k=*** load of mo fiber and interface bonding strength appear the maximum at k=4,followed by k=5,k=3 the third,and k=7 the *** k=4,mechanical properties of mo fiber-reinforced GPC are optimal,which is consistent with the result of theoretical *** study is of great significance to get better component formulas of mo fiber reinforced GPC and to improve its application in machine tools.

关键词： polymer composite fiber mechanical strength interface bonding

Recent progress in Ni-rich layered oxides and related cathode materials for Li-ion cells

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International Journal of Minerals,Metallurgy and Materials 2024年第11期31卷 2345-2367页

作者： Boyang Fu Maciej moździerz Andrzej Kulka Konrad Świerczek Faculty of Energy and Fuels AGH University of Krakowal.A.Mickiewicza 3030-059 KrakowPoland AGH Centre of Energy AGH University of Krakowul.Czarnowiejska 3630-054 KrakowPoland

Undoubtedly,the enormous progress observed in recent years in the Ni-rich layered cathode materials has been crucial in terms of pushing boundaries of the Li-ion battery(LIB)*** achieved improvements in the energy density,cyclability,charging speed,reduced costs,as well as safety and stability,already contribute to the wider adoption of LIBs,which extends nowadays beyond mobile electronics,power tools,and electric vehicles,to the new range of applications,including grid storage *** numerous published papers and broad reviews already available on the subject of Ni-rich oxides,this review focuses more on the most recent progress and new ideas presented in the literature *** covered topics include doping and composition optimization,advanced coating,concentration gradient and single crystal materials,as well as innovations concerning new electrolytes and their modification,with the application of Ni-rich cathodes in solid-state batteries also *** cathode materials are briefly mentioned,with the high-entropy approach and zero-strain concept presented as well.A critical overview of the still unresolved issues is given,with perspectives on the further directions of studies and the expected gains provided.

关键词： lithium-ion batteries cathode materials nickel-rich layered oxides recent progress critical issues improvement strategies