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Growth of Nano-Sb_2O_3 on Mica Substrates and Flame Retardant Properties

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Journal of China University of Mining and Technology 2006年第3期16卷 266-269页

作者： FENG Li LIU Jiong-tian WANG Bing-guo song Shuo-jiang School of Chemical Engineering and Technology China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China

In this paper, the Sb2O3 nanoparticles prepared with SbCl3 by the alky hydrolysis, processed with the surfactants, were assembled on mica substrates. The morphology and the assembled behavior of the nano-Sb2O3 on the mica were analyzed by means of TEM. The flame retardant properties of nano-Sb2O3 and Sb2O3/mica complex were studied by combustion test and thermal analysis. The results show that the Sb2O3 nanoparticles are assembled uniformly on the mica substrates. The nano-Sb2O3 was characterized with small size, narrow size distribution, uniform crystal and monodispersed particles. Compared with nano-Sb2O3, the Sb2O3/mica complexes have been achieved the same coordinated effects with Chlorinated Paraffin(CP) and excellent flame retardant properties.

关键词： Sb2O3 nanoparticle mica flame retardant chlorinated-paraffin

Stable knockdown of heparanase expression in gastric cancer cells in vitro

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World Journal of Gastroenterology 2009年第43期15卷 5442-5448页

作者： Li-Duan Zheng guo-song jiang Jia-Rui Pu Hong Mei Ji-Hua Dong Xiao-Hua Hou Qiang-song Tong Department of Pathology Union Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China Department of Surgery Union Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China Department of Central Laboratory Union Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China Department of Gastroenterology Union Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China

AIM:To develop short hairpin RNA(shRNA)against heparanase,and to determine its effects on heparanase expression and the malignant characteristics of gastric cancer cells. METHODS:Heparanase-specific shRNA was constructed and transferred into cultured the gastric cancer cell line *** subclonal cells were screened by G418 *** expression was measured by reverse transcriptase-polymerase chain reaction(RT-PCR),real-time quantitative PCR and Western *** proliferation was detected by 2-(4,5-dimethyltriazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT)colorimetry and colony formation assay. The in vitro invasiveness and metastasis of cancer cells were measured by cell adhesion assay,wound healingassay and matrigel invasion *** angiogenesis capabilities of cancer cells were measured by tube formation of endothelial cells. RESULTS:Stable transfection of heparanase-specific shRNA,but not of scrambled shRNA and mock vector,resulted in reduced mRNA and protein levels of *** shRNA-mediated knockdown of heparanase did not affect the cellular proliferation of SGC-7901 ***,the in vitro invasiveness and metastasis of cancer cells were decreased after knockdown of ***,transfection of heparanase-specific shRNA decreased the in vitro angiogenesis capabilities of SGC-7901 cells. CONCLUSION:Stable knockdown of heparanase can efficiently decrease the invasiveness,metastasis and angiogenesis of human gastric cancer *** contrast,stable knockdown of heparanase does not affect the cell proliferation.

关键词： Gastric cancer Heparanase RNA interference Invasion Metastasis

ARID1A Inactivation Increases Expression of circ0008399 and Promotes Cisplatin Resistance in Bladder Cancer

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Current Medical Science 2023年第3期43卷 560-571页

作者： Yang-kai jiang Yu-jun SHUAI Hua-min DING Hui ZHANG Chao HUANG Liang WANG Jia-yin SUN Wen-jie WEI Xing-yuan XIAO guo-song jiang Department of Urology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Urology Jingshan Union Hospital of Huazhong University of Science and Technology(People's Hospital of Jingshan)Jingshan 431899China

Objective Cisplatin(CDDP)-based chemotherapy is a first-line,drug regimen for muscle-invasive bladder cancer(BC)and metastatic bladder ***,resistance to CDDP restricts the clinical benefit of some bladder cancer ***-rich interaction domain 1A(ARID1A)gene mutation occurs frequently in bladder cancer;however,the role of CDDP sensitivity in BC has not been *** We established ARID1A knockout BC cell lines using CRISPR/Cas9 ***50 determination,flow cytometry analysis of apoptosis,and tumor xenograft assays were performed to verify changes in the CDDP sensitivity of BC cells losing ***-PCR,Western blotting,RNA interference,bioinformatic analysis,and ChIP-qPCR analysis were performed to further explore the potential mechanism of ARID1A inactivation in CDDP sensitivity in *** It was found that ARID1A inactivation was associated with CDDP resistance in BC ***,loss of ARID1A promoted the expression of eukaryotic translation initiation factor 4A3(EIF4A3)through epigenetic *** expression of EIF4A3 promoted the expression of hsa_circ_0008399(circ0008399),a novel circular RNA(circRNA)identified in our previous study,which,to some extent,showed that ARID1A deletion caused CDDP resistance through the inhibitory effect of circ0008399 on the apoptosis of BC ***,EIF4A3-IN-2 specifically inhibited the activity of EIF4A3 to reduce circ0008399 production and restored the sensitivity of ARID1A inactivated BC cells to *** Our research deepens the understanding of the mechanisms of CDDP resistance in BC and elucidates a potential strategy to improve the efficacy of CDDP in BC patients with ARID1A deletion through combination therapy targeting EIF4A3.

关键词： AT-rich interaction domain 1A hsa_circ_0008399 eukaryotic translation initiation factor 4A3 cisplatin resistance bladder cancer

Anomaly Detection of Controllable Electric Vehicles through Node Equation against Aggregation Attack

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Computers, Materials & Continua 2025年第1期82卷 427-442页

作者： Jing guo Ziying Wang Yajuan guo Haitao jiang State Grid jiangsu Electric Power Co. Ltd.Research InstituteState Grid Corporation of ChinaNanjing211100China

The rapid proliferation of electric vehicle(EV)charging infrastructure introduces critical cybersecurity vulnerabilities to power grids *** study presents an innovative anomaly detection framework for EV charging stations,addressing the unique challenges posed by third-party aggregation *** approach integrates node equations-based on the parameter identification with a novel deep learning model,xDeepCIN,to detect abnormal data reporting indicative of aggregation *** employ a graph-theoretic approach to model EV charging networks and utilize Markov Chain Monte Carlo techniques for accurate parameter *** xDeepCIN model,incorporating a Compressed Interaction Network,has the ability to capture complex feature interactions in sparse,high-dimensional charging *** results on both proprietary and public datasets demonstrate significant improvements in anomaly detection performance,with F1-scores increasing by up to 32.3%for specific anomaly types compared to traditional methods,such as wide&deep and DeepFM(Factorization-Machine).Our framework exhibits robust scalability,effectively handling networks ranging from 8 to 85 charging ***,we achieve real-time monitoring capabilities,with parameter identification completing within seconds for networks up to 1000 *** research contributes to enhancing the security and reliability of renewable energy systems against evolving cyber threats,offering a comprehensive solution for safeguarding the rapidly expanding EV charging infrastructure.

关键词： Anomaly detection electric vehicle aggregation attack deep cross-network

Constraints on holographic QCD phase transitions from PTA observations

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 71-78页

作者： song He Li Li Sai Wang Shao-jiang Wang Center for Theoretical Physics and College of Physics Jilin University School of Physical Science and Technology Ningbo University Max Planck Institute for Gravitational Physics (Albert Einstein Institute) CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences (UCAS) School of Physical Sciences University of Chinese Academy of Sciences (UCAS) Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences

The underlying physics of QCD phase transition in the early Universe remains largely unknown due to its strong-coupling nature during the quark-gluon plasma/hadron gas transition, yet a holographic model has been proposed to quantitatively fit the lattice QCD data while with its duration of the first-order phase transition(FoPT) left undetermined. At specific baryon chemical potential, the first-order QCD phase transition agrees with the observational constraint of baryon asymmetry. It, therefore, provides a scenario for phase transition gravitational waves(GWs) within the standard model of particle physics. If these background GWs could contribute dominantly to the recently claimed common-spectrum red noise from pulsar timing array(PTA) observations, the duration of this FoPT can be well constrained, and the associated primordial black holes are still allowed by current observations.

关键词： pulsar timing array QCD phase transition gravitational waves primordial black holes

A robust statistical prediction model for late-summer heavy precipitation days in North China

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Science China Earth Sciences 2025年第1期68卷 158-171页

作者： Shunli jiang Tingting HAN Xin ZHOU Huijun WANG Zhicong YIN Xiaolei song Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters/Key Laboratory of Meteorological Disaster Ministry of Education Nanjing University for Information Science and Technology Nansen-Zhu International Research Centre Institute of Atmospheric Physics Chinese Academy of Sciences Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)

Recently, heavy precipitation(HP) events have occurred frequently in North China(NC), causing devastating economic losses and human fatalities. However, the short-term climate prediction of HP is quite limited. Combining year-to-year increment(DY) method and sliding correlations, we developed a robust seasonal prediction model for late-summer HP days(HPDs) in NC during 1982–2022, utilizing three independent predictors—February sea surface temperature(SST) in the Indian Ocean(SST＿IO), February snow depth over North Asia(SDE＿NA), and May melted snow depth in NC(MSDE＿NC). The SST＿IO anomalies affect NC's precipitation through the Pacific-Japan pattern. The SDE＿NA anomalies are associated with East Asian anomalous anticyclone by southeastern propagation of Rossby wave at Eurasia. The MSDE＿NC anomalies are followed by vertical motion and moisture anomalies in situ and thereby cause precipitation anomalies. This prediction model can well simulate the variations of the HPDs, with a correlation coefficient(CC) of 0.81(0.65) between the observed and predicted HPDs＿DY(HPDs＿anomaly). The percentage with the same sign for 15 extreme HPDs＿anomaly years(PSSE) is 100%.Moreover, in the cross-validation test during 1982–2022, the PSSE for HPDs＿anomaly is as high as 100%, along with a low rootmean-square error of 1.14. For independent hindcasts during 2013–2022, the CC between the observed and predicted HPDs＿DY(HPDs＿anomaly) is 0.93(0.83), together with high Nash-Sutcliffe efficiency(0.82) and agreement index(0.89). Specifically, the predictions are broadly consistent with the observations for 2015, 2016, 2017, 2021, and 2022, reflecting excellent performance of this prediction model of HPDs in NC.

关键词： Heavy precipitation at North China Year-to-year increment approach Robust seasonal prediction Sea surface temperature Snow depth

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和谐社会构建视野下的阶层利益协调

中南民族大学学报（人文社会科学版） 2008年第1期28卷 86-89页

作者：郭松江中南民族大学思想政治教育学院湖北武汉430074

随着小康社会建设的全面发展,我国社会阶层结构发生了深刻的变化。阶层结构的新变化、新融合与新发展是和谐社会构建中一个崭新的研究课题。由此,协调阶层利益,化解阶层各种矛盾,防止阶层冲突对立,使阶层互融互动,形成推动社会发展的合... 详细信息

随着小康社会建设的全面发展,我国社会阶层结构发生了深刻的变化。阶层结构的新变化、新融合与新发展是和谐社会构建中一个崭新的研究课题。由此,协调阶层利益,化解阶层各种矛盾,防止阶层冲突对立,使阶层互融互动,形成推动社会发展的合力,对和谐社会构建具有极其重要的意义。从两者的关系看,其着力点表现在:阶层利益协调是构建和谐社会的基础,也是推动和谐社会发展的动力。新的历史时期,阶层利益协调要有新思维。

关键词：和谐社会构建阶层利益协调新思维

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新视角下毛泽东社会主义建设思想再解读

中南民族大学学报（人文社会科学版） 2009年第4期29卷 87-91页

作者：郭松江中南民族大学思想政治教育学院湖北武汉420074

新的历史时期对毛泽东社会主义建设思想进行再解读,具有非常重要的现实意义。毛泽东社会主义建设思想具有丰富而深刻的内涵,但也不可避免地带有一定的历史局限性。新的历史时期毛泽东社会主义建设思想也在不断创新发展,最主要的表现是:... 详细信息

新的历史时期对毛泽东社会主义建设思想进行再解读,具有非常重要的现实意义。毛泽东社会主义建设思想具有丰富而深刻的内涵,但也不可避免地带有一定的历史局限性。新的历史时期毛泽东社会主义建设思想也在不断创新发展,最主要的表现是:民主政治制度建设理论、意识形态建设理论和社会建设理论的创新发展。

关键词：新视角毛泽东社会主义建设思想再解读

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论人与和谐社会的融合发展

河南师范大学学报（哲学社会科学版） 2007年第6期34卷 195-198页

作者：郭松江中南民族大学思想政治教育学院湖北武汉420073

要实现党提出的建设和谐社会的宏伟目标,必须注重人与社会的融合与共同发展。人的全面发展是党执政的重要思想,是构建和谐社会的基石,也是推动和谐社会向更高层面转化的关键。而和谐社会也要为人的发展提供更为完善的政治条件、思想条... 详细信息

要实现党提出的建设和谐社会的宏伟目标,必须注重人与社会的融合与共同发展。人的全面发展是党执政的重要思想,是构建和谐社会的基石,也是推动和谐社会向更高层面转化的关键。而和谐社会也要为人的发展提供更为完善的政治条件、思想条件和利益条件。在新的历史时期,人与和谐社会发展的新内涵具体表现在:人与人之间要建立起新型的社会关系,要进一步提高党的执政能力建设,巩固社会主义制度,建立新的社会和谐构架,尤其要把人与社会的发展、时代的发展紧密地相融在一起。

关键词：人的全面发展和谐社会构建基石条件新内涵