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The role of mergers and gas accretion in black hole growth and galaxy evolution

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Research in Astronomy and Astrophysics 2021年第8期21卷 293-302页

作者： Tian-Chi Zhang Qi guo Yan qu Liang Gao Key Laboratory for Computational Astrophysics National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China Institute of Computational Cosmology Department of PhysicsUniversity of DurhamSouth RoadDurham DH13LEUK

We use a semi-analytic galaxy formation model to study the co-evolution of supermassive black holes(SMBHs) with their host *** the coalescence of SMBHs is not important,the quasarmode accretion induced by mergers plays a dominant role in the growth of *** play a more important role in the growth of SMBH host galaxies than in the SMBH *** is the combined contribution from quasar mode accretion and mergers to the SMBH growth and the combined contribution from starburst and mergers to their host galaxy growth that determine the observed scaling relation between the SMBH masses and their host galaxy *** also find that mergers are more important in the growth of SMBH host galaxies compared to normal galaxies which share the same stellar mass range as the SMBH host galaxies.

关键词： methods:numerical galaxies:evolution (galaxies:)quasars:supermassive black holes

Harmful Intrusion Detection Algorithm of Optical Fiber Pre-Warning System Based on Correlation of Orthogonal Polarization Signals

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Photonic Sensors 2017年第3期7卷 226-233页

作者： Fukun BI Chong feng Hongquan qu Tong ZHENG Chonglei WANG School of Electrical and Information Engineering North China University of Technology Beijing 100144 China Beijing Institute of Technology Department of Information and Electronic Beijing 100081 China

At present, advanced researches of optical fiber intrusion measurement are based on the constant false alarm rate （CFAR） algorithm. Although these conventional methods overcome the interference of non-stationary random signals, there are still a large number of false alarms in practical applications. This is because there is no specific study on orthogonal polarization signals of false alarm and intrusion. In order to further reduce false alarms, we analyze the correlation of optical fiber signals using birefringence of single-mode fiber. This paper proposes the harmful intrusion detection algorithm based on the correlation of two orthogonal polarization signals. The proposed method uses correlation coefficient to distinguish false alarms and intrusions, which can decrease false alarms. Experiments on real data, which are collected from the practical environment, demonstrate that the difference in correlation is a robust feature. Furthermore, the results show that the proposed algorithm can reduce the false alarms and ensure the detection performance when it is used in optical fiber pre-warning system （OFPS）.

关键词： Optical fiber birefringence orthogonal polarization signals correlation

High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast

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Frontiers of Medicine 2023年第5期17卷 907-923页

作者： Dawei Xie Zheng Wang Beibei Sun Liwei qu Musheng Zeng Lin feng Mingzhou guo Guizhen Wang Jihui Hao Guangbiao Zhou State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing100021China State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of Sciences&University of Chinese Academy of SciencesBeijing100101China State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer CenterGuangzhou510060China Department of Gastroenterology&Hepatology and Department of Pathology Chinese People’s Liberation Army General HospitalBeijing100853China Department of Pancreatic Cancer Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjin’s Clinical Research Center for CancerTianjin300060China

The characteristic genetic abnormality of neuroendocrine neoplasms(NENs),a heterogeneous group of tumors found in various organs,remains to be ***,based on the analysis of the splicing variants of an oncogene Focal Adhesion Kinase(FAK)in The Cancer Genome Atlas datasets that contain 9193 patients of 33 cancer subtypes,we found that Box 6/Box 7-containing FAK variants(FAK^(6/7))were observed in 7(87.5%)of 8 pancreatic neuroendocrine carcinomas and 20(11.76%)of 170 pancreatic ductal adenocarcinomas(PDACs).We tested FAK variants in 157 tumor samples collected from Chinese patients with pancreatic tumors,and found that FAK^(6/7)was positive in 34(75.6%)of 45 pancreatic NENs,19(47.5%)of 40 pancreatic solid pseudopapillary neoplasms,and 2(2.9%)of 69 *** further tested FAK splicing variants in breast neuroendocrine carcinoma(BrNECs),and found that FAK^(6/7)was positive in 14(93.3%)of 15 BrNECs but 0 in 23 non-NEC breast *** explored the underlying mechanisms and found that a splicing factor serine/arginine repetitive matrix protein 4(SRRM4)was overexpressed in FAK^(6/7)-positive pancreatic tumors and breast tumors,which promoted the formation of FAK^(6/7)in *** results suggested that FAK^(6/7)could be a biomarker of NENs and represent a potential therapeutic target for these orphan diseases.

关键词： FAKFAK^(6/7) SRRM4 neuroendocrine neoplasms pancreas breast SRRM4 neuroendocrine neoplasms pancreas breast

Amperometric Determination of lndole-3-acetic Acid Based on Platinum Nanowires and Carbon Nanotubes

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Chinese Chemical Letters 2006年第12期17卷 1585-1588页

作者： Ruo Zhong WANG Lang Tao XIAO Ming Hui YANG Jun Hui DING feng Li qu guo Li-SHEN Hunan Provincial Key Laboratory of Phytohormones and Growth Development Hunan Agricultural University Changsha 410028 Chemistry and Chemical Engineering College State Key Laboratory of Chemo/Biosensing and Chemometrics Hunan University Changsha 410082

Platinum nanowire （PtNW） can be grown by electrodeposition in polycarbonate membrane, with the average diameter of the nanowires about 250 nm. The PtNW and multiwalled carbon nanotubes （CNT） are then dispersed into chitosan （CHIT） solution. The resulting PtNW-CNT-CHIT material brings new capabilities for electrochemical devices by using the synergistic action of the electrocatalytic activity of PtNW and CNT. By dropping the PtNW-CNT-CHIT film onto the glassy carbon （GO） electrode surface, and after evaporation an amperometric sensor for the determination of indole-3-acetic acid （IAA） was developed. The oxidation current of IAA increased significantly at the PtNW-CNT-CHIT film coated GC electrode, in contrast to that at the CNT-CHIT modified GC. The linear response of the sensor is from 50 ng/ml to 50 μg/ml with a detection limit of 25 ng/mL.

关键词： Chitosan platinum nanowire glassy carbon indole-3-acetic acid.

Dzyaloshinsky–Moriya interaction(DMI)-induced magnetic skyrmion materials

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Rare Metals 2021年第11期40卷 3076-3090页

作者： Wen-Sen Wei Zhi-Dong He Zhe qu Hai-feng Du Anhui Province Key Laboratory of Condensed Matter Physics at Extreme Conditions High Magnetic Field Laboratory of Chinese Academy of SciencesUniversity of Science and Technology of ChinaHefei 230031China Institutes of Physical Science and Information Technology Anhui UniversityHefei 230601China

A magnetic skyrmion is a particle-like spin swirling object with a nontrivial topology that holds great promise for next-generation information carriers in highperformance spintronic *** was discovered in a chiral magnet,MnSi with B20 structure,in 2009 and later confirmed as a common feature of magnetic compounds with Dzyaloshinsky-Moriya interaction(DMI).In this work,we provide fundamental insight into the magnetic properties of skyrmion-hosting materials originating from *** relationship between the point groups of the materials and DMI is introduced;then,the common features of magnetic skyrmions experimentally verified in the magnetization and magnetotransport measurements are ***,other particle-like magnetic configurations in chiral magnets and the crossover with a superconductor are discussed.

关键词： Magnetic skyrmions Skyrmion materials Dzyaloshinsky–Moriya interaction

1-Methoxycarbony-β-carboline from Picrasma quassioides exerts anti-angiogenic properties in HUVECs in vitro and zebrafish embryos in vivo

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Chinese Journal of Natural Medicines 2018年第8期16卷 599-609页

作者： LIN Qing-Hua qu Wei XU Jian feng feng HE Ming-Fang Department of Natural Medicinal Chemistry China Pharmaceutical University Key Laboratory of Biomedical Functional Materials China Pharmaceutical University Institute of Translational Medicine College of Biotechnology and Pharmaceutical EngineeringNanjing Tech University

Angiogenesis is a crucial process in the development of inflammatory diseases,including cancer,psoriasis and rheumatoid ***,several alkaloids from Picrasma quassioides had been screened for angiogenic activity in the zebrafish model,and the results indicated that 1-methoxycarbony-β-carboline(MCC) could effectively inhibit blood vessel *** this study,we further confirmed that MCC can inhibit,in a concentration-dependent manner,the viability,migration,invasion,and tube formation of human umbilical vein endothelial cells(HUVECs) in vitro,as well as the regenerative vascular outgrowth of zebrafish caudal fin in *** the zebrafish xenograft assay,MCC inhibited the growth of tumor masses and the metastatic transplanted DU145 tumor *** proteome profile array of the MCC-treated HUVECs showed that MCC could down-regulate several angiogenesis-related self-secreted proteins,including ANG,EGF,b FGF,GRO,IGF-1,PLG and *** addition,the expression of two key membrane receptor proteins in angiogenesis,TIE-2 and u PAR,were also down-regulated after MCC *** together,these results shed light on the potential therapeutic application of MCC as a potent natural angiogenesis inhibitor via multiple molecular targets.

关键词： 1-Methoxycarbony-β-carboline Angiogenesis inhibitor HUVEC Zebrafish Anti-angiogenic index

Shared aperture metasurface antenna for electromagnetic vortices generation with different topological charges

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Chinese Physics B 2021年第8期30卷 337-344页

作者： He Wang Yong-feng Li Shao-Bo qu Department of Basic Sciences Air Force Engineering UniversityXi'an 710051China

Vortex beams carrying orbital angular momentum(OAM)have aroused great interest of both scientific and engineering ***,generating OAM with different topological charges in a shared aperture is regarded as a potential route to expanding the communication capacity,which yet is an academic challenging *** this work,a paradigm of designing metasurface-based shared aperture antenna for generating polarization-dependent vortex beams with distinct topological charges is *** unit cells that can tailor different resonance phase profiles in two orthogonal orientations are used to assemble a metasurface *** a proof-of-concept,a planar reflector antenna is designed with two Vivaldi sources,which can generate x-and y-polarized vortex beams with topological charges of l=-1 and l=-2,*** the simulation results and the measurement results are in good agreement,which demonstrates the feasibility of our ***,this work provides a new route to achieving vortex beams carrying different topological charges in the same frequency band,which may have potential applications in communication systems.

关键词： metasurface electromagnetic vortex antenna orbital angular momentum

Essential role of NbNOG1 in ribosomal RNA processing

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Journal of Integrative Plant Biology 2018年第11期60卷 1018-1022页

作者： Jiangbo guo Shaojie Han Jinping Zhao Cuihua Xin Xiyin Zheng Yule Liu Yan Wang feng qu School of Life Science and Technology Inner Mongolia University of Science and Technology MOE Key Laboratory of Bioinformatics Center for Plant Biology Tsinghua-Peking Joint Center for Life Sciences School of Life Sciences Tsinghua University Department of Plant Pathology the Ohio State University

Nucleolar GTP-binding protein 1（NOG1） is a highly conserved GTPase first reported in Trypanosoma as required for ribosome biogenesis. We characterized NbNOG1, a Nicotiana benthamiana NOG1ortholog sharing more than 45% amino acid identity with Trypanosoma,yeast, and human NOG1. N. benthamiana plants silenced for NbNOG1were stunted and produced sterile ***1is functionally interchangeable with yeast NOG1（ScNOG1）, rescuing yeast lethality caused by loss of ScNOG1. Finally, NbNOG1silencing caused overaccumulation of pre-rRNA processing intermediates,and concomitant loss of mature rRNAs. Collectively,these data support a role for NbNOG1in ribosomal RNA processing.

关键词： Essential role of NbNOG1 in ribosomal RNA processing Figure

Microcalorimetric Character of Inhibition of Salicylaldehyde Glucosamine Schiff Base SG on Bacterial Metabolism

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Chemical Research in Chinese Universities 1999年第1期15卷 49-53页

作者： HUANG Zai-ying qu Song-sheng feng Ying Department of Chemistry Wuhan UniversityWuhan430072

The power time curves of the reaction of *** with SG at different temperatures were determined by microcalorimetric method and the mutliplication rate constant k , generation time G , ratio I , and thermogenetic quantity Q , Q 0 and 0 were *** function formulas have been established. It was found that P max , t g, t and 0 can be used to characterize the bacterial growth metabolism of *** and the antibacterial activity of SG.

关键词： Salicylaldehyde glucosamine Schiff base Microcalorimetrey E.coli