检索结果-南通市图书馆

Increased excitatory amino acid transporter 2 levels in basolateral amygdala astrocytes mediate chronic stress–induced anxiety-like behavior

引用

Neural Regeneration Research 2025年第6期20卷 1721-1734页

作者： Xirong Xu Shoumin Xuan Shuai Chen Dan liu Qian xiao Jie Tu Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases Shenzhen-Hong Kong Institute of Brain ScienceShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina CAS Key Laboratory of Brain Connectome and Manipulation Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Brain Connectome and Behavior the Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina University of Chinese of Academy of Sciences BeijingChina Faculty of Life and Health Sciences Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina

The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain function and encoding behaviors associated with ***, astrocytes in the basolateral amygdala have been found to play a role in the modulation of anxiety-like behaviors triggered by chronic stress. Nevertheless, the precise molecular mechanisms by which basolateral amygdala astrocytes regulate chronic stress–induced anxiety-like behaviors remain to be fully elucidated. In this study, we found that in a mouse model of anxiety triggered by unpredictable chronic mild stress, the expression of excitatory amino acid transporter 2 was upregulated in the basolateral amygdala. Interestingly, our findings indicate that the targeted knockdown of excitatory amino acid transporter 2 specifically within the basolateral amygdala astrocytes was able to rescue the anxiety-like behavior in mice subjected to stress. Furthermore, we found that the overexpression of excitatory amino acid transporter 2 in the basolateral amygdala, whether achieved through intracranial administration of excitatory amino acid transporter 2agonists or through injection of excitatory amino acid transporter 2-overexpressing viruses with GfaABC1D promoters, evoked anxiety-like behavior in mice. Our single-nucleus RNA sequencing analysis further confirmed that chronic stress induced an upregulation of excitatory amino acid transporter 2 specifically in astrocytes in the basolateral amygdala. Moreover, through in vivo calcium signal recordings, we found that the frequency of calcium activity in the basolateral amygdala of mice subjected to chronic stress was higher compared with normal *** knocking down the expression of excitatory amino acid transporter 2 in the basolateral amygdala, the frequency of calcium activity was not significantly increased, and anxiety-like behavior was ob

关键词： anxiety astrocytes basolateral amygdala behavior dihydrokainic acid excitatory amino acid transporter 2 fiber photometry glutamate LDN-212320 transporter

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

非线性动力系统个体的脉冲协调控制

引用

计算机仿真 2014年第4期31卷 379-383,393页

作者：刘佳过榴晓胡满峰徐振源江南大学理学院江苏无锡214122

研究有向图连接的非线性个体协调控制的动力学模型问题,利用一致控制协议基于脉冲控制和采样点技术,研究非线性个体分别在强连接和生成树及其它网络拓扑结构连接下,选取适当的脉冲间隔,多智能体网络系统可以达到渐近一致。数值仿真验证... 详细信息

研究有向图连接的非线性个体协调控制的动力学模型问题,利用一致控制协议基于脉冲控制和采样点技术,研究非线性个体分别在强连接和生成树及其它网络拓扑结构连接下,选取适当的脉冲间隔,多智能体网络系统可以达到渐近一致。数值仿真验证了理论方法的有效性,针对非线性多智能个体一致性受到脉冲间隔及不同多智能体网络拓扑结构的影响,给出相同的耦合强度下容许的最大脉冲间隔,提高个体智能化,更好地提高效率。

关键词：多智能体一致性非线性个体脉冲控制有向图

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Amino acid assisted aqueous synthesis of highly stable CsPbBr_(3)nanocrystals for cell imaging

引用

Nano Research 2025年第1期18卷 675-683页

作者： Xue Li Yanan guo guoying Tan Qingyi liu Nan Song Yu Tang State Key Laboratory of Applied Organic Chemistry Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu ProvinceCollege of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000China State Key Laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive Utilization Baotou Research Institute of Rare EarthsBaotou 014030China

Lead halide perovskite nanocrystals(NCs)exhibit excellent optoelectronic performance and have drawn great interests in the fields of biological imaging and ***,the poor stability of CsPbX_(3)(X=Cl,Br,I)in water is still a challenge to hinder their practical *** this work,a facile strategy has been developed for aqueous synthesis of CsPbX_(3) nanocrystals,in which L-glutamic acid(LGlu)has been used to replace oleic acid in the synthetic *** from the synergic effects of L-Glu and oleylamine(OAm),CsPbBr_(3)nanocrystals(L-Glu/OAm-CsPbBr_(3)NCs)with high water stability have been directly prepared under a mild condition at room temperature in water,facilitated by the process of crystal phase transformation from Cs_(4)PbBr_(6) to CsPbBr_(3).L-Glu/OAm-CsPbBr_(3)NCs exhibit a high quantum yield of 85%and a narrow full width at half maximum of 16 nm,demonstrating their efficient luminescence in ***,L-Glu on the surface have contributed greatly to an acidic environment and passivation of surface defects,improving the water stability and dispersibility of CsPbBr_(3)***,L-Glu/OAm-CsPbBr_(3)NCs exhibit great biocompatibility due to the presence of L-Glu,resulting in their good performance for HeLa cell ***,we propose a facile and effective method to prepare CsPbBr_(3)nanocrystals with excellent water stability by using L-Glu and OAm as cooperated ligands and expand their application in cell imaging.

关键词： aqueous synthesis cell imaging lead halide perovskite nanocrystals L-glutamic acid phase transformation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Robinson-Ursescu定理在Frechet空间中的形成

引用

江南大学学报（自然科学版） 2005年第5期4卷 541-544页

作者：过榴晓丘京辉江南大学理学院江苏无锡214122 苏州大学理学院江苏苏州215006

由局部凸F-范空间中闭凸集值映射的性质,推导出Frechet空间上集值映射的Robinson-Ursescu定理、开映照与闭图定理形式.

关键词： Frechet空间凸集值映射 Robinson-Ursescu定理开映照与闭图定理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Atomically precise nickel-sulfur clusters for efficient electrochemical 2,5-hydroxymethylfurfural oxidation

引用

Nano Research 2025年第1期18卷 140-148页

作者： Fen Wang Lu-Yu liu Sha-Sha Cui Ting-Ting Li xiao-Meng Yang Zhijuan liu Yanyong Wang Henan Key Laboratory of Crystalline Molecular Functional Materials Henan International Joint Laboratory of Tumor Theranostical Cluster MaterialsGreen Catalysis Centerand College of ChemistryZhengzhou UniversityZhengzhou 450001China State Key Laboratory of Chem/Bio-sensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China

Nickel sulfide exhibits excellent catalytic activity in the electrochemical 2,5-hydroxymethylfurfural oxidation reaction(HMFOR).However,due to the polydispersity of nanoparticles,it is difficult to establish a clear structure-activity relationship at the atomic *** this work,we have successfully synthesized atomically precise Ni_(6)(PET)_(12)and Ni_(4)(PET)_(8)clusters(PET:2-phenylethanethiol)for ***^(2+)and S_(2)-with atomic ratio of 1:2 was mainly existed in Ni_(6)(PET)_(12)and Ni_(4)(PET)_(8)to form Ni-S *** electrochemical test results have suggested both Ni_(6)(PET)_(12)and Ni_(4)(PET)_(8)displayed outstanding electrocatalytic ability for *** Ni_(6)(PET)_(12)exhibited better electrocatalytic ability than Ni_(4)(PET)_(8)with higher current density,lower overpotential and faster reaction *** superior electrochemical ability of Ni_(6)(PET)_(12)may be due to the enhanced adsorption towards HMF molecule with strong interaction towards hydroxyl group and furan ***,it found that the Ni^(2+)species in Ni_(6)(PET)_(12)could rapidly oxidized into Ni^(3+)species,which could spontaneously capture electron and proton from HMF for *** theoretical calculation demonstrated that the Ni_(6)(PET)_(12)process lower free energy barrier than Ni_(4)(PET)_(8)to display excellent electrocatalytic *** work is of great significance for designing efficient electrocatalysts for HMFOR.

关键词： atomically precise nickel nanoclusters 2 5-hydroxymethylfurfural electro-oxidation Ni3+species

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hierarchical hollow microspheres assembled from carbon nanosheets integrated with molybdenum carbide nanoparticles for boosting microwave absorption properties

引用

Nano Research 2025年第1期18卷 10-20页

作者： Zongsheng Chen Yahui Wang Yi liu Zhigang Li Xiangyin Lv Liping liu Yajing Chang Jiaming Shi xiao Zhang State Key Laboratory of Pulsed Power Laser Technology School of Electronic EngineeringNational University of Defense TechnologyHefei 230037China Anhui Provincial Laboratory of Advanced Laser Technology School of Electronic EngineeringNational University of Defense TechnologyHefei 230037China Centre for Environmental and Energy Nanomaterials Anhui Key Laboratory of Nanomaterials and NanotechnologyCAS Centre for Excellence in NanoscienceInstitute of Solid State PhysicsHefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China

Hierarchical hollow structure has demonstrated potential for enhancing electromagnetic(EM)attenuation and improving impedance matching,garnering significant attention for ***,we have successfully implemented compositional and structural engineering to fabricate hollow Mo2C/C microspheres with controllable composition by coupling interaction between dopamine hydrochloride and ammonium *** the synergistic effect of composition and hollow structure,the strongest reflection loss intensity and broadest effective absorption of the optimized sample reach-70.2 dB and 6.2 GHz,*** formation of hollow heterogeneous structures not only favors impedance matching feature,but also generates considerable contribution to EM attenuation ***,radar cross-section simulation data indicate that hollow Mo2C/C microspheres with compositional optimization and heterogeneous structures have broad prospects for practical applications.

关键词： electromagnetic absorption Mo2C/C microwave absorption hollow structure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

供给侧结构性改革推进东北地区产业结构调整

引用

哈尔滨商业大学学报（社会科学版） 2017年第1期 94-99页

作者：郭振刘晓娟哈尔滨商业大学经济学院哈尔滨150028

东北地区传统工业结构和所有制结构单一,高端制造业市场份额偏低,服务业发展滞后以及要素配置失衡等因素导致产业结构调整步伐缓慢,进而阻碍了产业升级和经济的可持续发展,产业结构调整优化亟需从供给侧发力,通过结构性调整,破除旧的产... 详细信息

东北地区传统工业结构和所有制结构单一,高端制造业市场份额偏低,服务业发展滞后以及要素配置失衡等因素导致产业结构调整步伐缓慢,进而阻碍了产业升级和经济的可持续发展,产业结构调整优化亟需从供给侧发力,通过结构性调整,破除旧的产业发展瓶颈。通过研究供给侧结构性改革与产业结构调整之间的逻辑关系,分析当前东北地区产业结构的现状与问题,提出基于供给侧结构性改革改善劳动力有效供给,实施创新驱动战略,发展现代服务业,创新制度供给,推动东北地区产业结构的优化升级。

关键词：东北地区供给侧结构性改革产业结构调整产业结构优化升级

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

城市二级污水处理厂的事故环境风险研究

引用

太原理工大学学报 2008年第S1期39卷 152-155页

作者：崔建国刘晓霞肖致美太原理工大学环境科学与工程学院山西太原030024

依据A2/O污水处理工艺的设计计算方法推导了污水处理厂事故出水BOD5、TN和TP的预测模型,提出了污水厂产生事故时不同用途出水的环境风险评价方法。实例研究表明,事故时当原水只经过一级处理后,出水的环境风险不可避免。若事故产生在二... 详细信息

依据A2/O污水处理工艺的设计计算方法推导了污水处理厂事故出水BOD5、TN和TP的预测模型,提出了污水厂产生事故时不同用途出水的环境风险评价方法。实例研究表明,事故时当原水只经过一级处理后,出水的环境风险不可避免。若事故产生在二级处理单元时,出水产生的环境风险可通过调整曝气量、回流比或排泥量等工艺参数加以减少。

关键词：污水处理预测模型 A2/O工艺环境风险

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

海底爆破辐射声场的理论及数值研究

引用

物理学报 2008年第7期57卷 4251-4257页

作者：汤立国许肖梅刘胜兴厦门大学海洋学系

对固体基底浅海中声波传播的色散特性作了数值模拟与分析.利用液体及固体中声传播理论导出了固体基底内爆破源在浅海中所激发声场的解析解,在此基础上,通过数值计算,得出了浅海中不同空间点处的瞬态声压时域波形,并在瞬态声压时域波形... 详细信息

对固体基底浅海中声波传播的色散特性作了数值模拟与分析.利用液体及固体中声传播理论导出了固体基底内爆破源在浅海中所激发声场的解析解,在此基础上,通过数值计算,得出了浅海中不同空间点处的瞬态声压时域波形,并在瞬态声压时域波形的平滑伪Wigner-Ville分布基础上,对固体基底内爆破源在浅海中所激发瞬态声场的特性作了详细分析.

关键词：海底爆破声场色散瞬态声压

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

珊瑚树(Viburnum odoratissinum)对污染土壤中镉的耐受和富集特征

引用

生态学报 2017年第19期37卷 6472-6479页

作者：曾鹏曹霞郭朝晖肖细元刘亚男辛立庆中南大学冶金与环境学院环境工程研究所长沙410083

通过温室盆栽试验,研究珊瑚树对土壤中镉(Cd)的耐受和富集特征。研究结果表明,珊瑚树对污染土壤中Cd具有较强的耐受能力。培养56 d内,土壤中Cd含量对珊瑚树生物量影响不明显;随着培养时间的延长(105—203 d),珊瑚树的生长明显受到土壤... 详细信息

通过温室盆栽试验,研究珊瑚树对土壤中镉(Cd)的耐受和富集特征。研究结果表明,珊瑚树对污染土壤中Cd具有较强的耐受能力。培养56 d内,土壤中Cd含量对珊瑚树生物量影响不明显;随着培养时间的延长(105—203 d),珊瑚树的生长明显受到土壤中Cd的抑制作用。与对照处理(土壤中Cd含量为3.6 mg/kg)相比,培养154 d后,土壤中Cd含量为24.6 mg/kg处理下珊瑚树叶片中叶绿素a、叶绿素b、类胡萝卜素和丙二醛(MDA)含量没有明显变化;培养203 d后,土壤中Cd含量为24.6mg/kg处理下珊瑚树叶片中类胡萝卜素和MDA含量无明显变化,但叶片中叶绿素a和叶绿素b含量明显受到抑制,从而导致珊瑚树叶片的生长明显受到抑制(P<0.05)。培养203 d后,珊瑚树对土壤中Cd的富集系数和转运系数均大于1,表明珊瑚树对土壤中Cd具有一定的富集和转运能力。上述结果表明,珊瑚树对Cd污染土壤具有一定的生态修复潜力。

关键词： Cd 污染土壤景观植物植物修复珊瑚树

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：