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Efficacy and prognostic impact of Pericarpium Trichosanthis injection combined with nicorandil for intractable angina pectoris in elderly patients: A retrospective study

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World Journal of Cardiology 2023年第12期15卷 633-641页

作者： Jun Li Mo-Wei Kong Yu-Yu Xie Ze-Bi Wang Li Xu guo-xiang he Department of Cardiology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina Department of Dermatology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina

BACKGROUND Coronary artery disease(CAD)is a leading cause of global cardiovascular *** angina pectoris,a manifestation of CAD,requires effective drug *** Trichosanthis injection,a traditional Chinese medicine,improves cardiovascular symptoms,while nicorandil alleviates spasms and *** have potential in treating *** To investigate the therapeutic effects of combining Pericarpium Trichosanthis injection and nicorandil in elderly patients suffering from refractory angina caused by coronary heart *** A retrospective analysis was conducted on the data of 130 patients diagnosed with refractory coronary heart *** on the different treatment regimens administered during hospitalization,the patients were divided into a control group(58 cases)and a study group(72 cases).The control group received conven-tional treatment,which included aspirin,statins,and nitrate *** addition to the conventional medication,the study group received a combination treatment of Pericarpium Trichosanthis injection and *** After treatment,the study group showed significantly higher left ventricular ejection fraction and cardiac output,and lower brain natriuretic peptide and C-reactive protein levels compared to the control *** study group also exhibited improvements in angina,quality of life,exercise endurance,and lipid *** logistic regression analysis revealed a relationship of lipid levels and heart function with the combined *** patients in the study group experienced headaches during treatment,but no significant adverse reactions were ***-up showed that the treatment was well-tolerated,with no drug-related adverse reactions *** Combination of Pericarpium Trichosanthis injection and nicorandil is more effective than conventional treatment in improving symptoms and heart function in elderly patients with refractory angina pectoris.

关键词： Pericarpium Trichosanthis injection Coronary heart disease Intractable angina pectoris Nicorandil

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Down syndrome child with multiple heart diseases: A case report

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World Journal of Cardiology 2023年第11期15卷 615-622页

作者： Mo-Wei Kong Yi-Jing Li Jun Li Zhen-Ying Pei Yu-Yu Xie guo-xiang he Department of Cardiology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina Department of Dermatology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina

BACKGROUND Down syndrome,also known as trisomy 21 syndrome,is commonly associated with congenital heart disease,and can often result in early formation of pulmonary *** development of pulmonary hypertension can result from factors such as intracardiac and macrovascular shunts,and upper airway obstruction or hypoplasia of lung *** with Down syndrome and congenital heart disease have a significantly lower average life expectancy,with surgical intervention being the most viable treatment option to improve *** SUMMARY We report the case of a 13-year-old boy with Down syndrome presenting with atrial septal defect and patent ductus arteriosus along with severe pulmonary *** electrocardiogram shows sinus rhythm and right ventricular *** echocardiogram shows an atrial septal defect with interrupted echo in the interatrial septum,measuring 0.813 cm in *** patient was initially refused to be offered surgical treatment by many hospitals due to the high surgical risk and pulmonary artery *** discussing the patient’s diagnosis and treatment options,we ultimately recommended surgical ***,the patient and their family declined this recommendation and chose to be *** the follow-up period of 6 mo,there were no significant improvements or deteriorations in the patient’s *** In conclusion,this case highlights the challenges faced by individuals with Down syndrome and congenital heart disease complicated by severe pulmonary *** intervention and a multidisciplinary approach are crucial for improving prognosis and life *** research is needed to enhance our understanding and develop effective interventions for this *** Tip:This case study presents a 13-year-old boy diagnosed with Down syndrome alongside atrial septal defect,patent ductus arteriosus,and severe pulmonary hypertension.A complex condition initially met with

关键词： Down initially holds

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World Journal of Cardiology 2023年第10期15卷 479-486页

作者： Mo-Wei Kong Zhen-Ying Pei Xiong Zhang Qiu-Juan Du Qiang Tang Jun Li guo-xiang he Department of Cardiology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina

Despite the high prevalence of straight back syndrome(SBS),there is still limited research on this condition,posing challenges for effective diagnosis and *** disease has been known for a long time,but there have been few related studies,which mostly consist of case *** studies have not been systematically summarized,making it difficult to meet the current needs of diagnosis and *** article summarized the existing literature and comprehensively reviewed the diagnosis,pathogenesis,treatment,and research status of mitral valve prolapse related to *** specifically emphasized the mechanisms and prognosis of SBS combined with mitral valve prolapse and discussed the latest research progress in this disease.

关键词： Straight back syndrome Mitral valve prolapse Arrhythmia Review Diagnosis Treatment

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Cardiotoxicity induced by fluoropyrimidine drugs in the treatment of gastrointestinal tumors

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 251-254页

作者： Mo-Wei Kong Feng-Di Sun Zhen-Ying Pei Li Xu Ze-Bi Wang Yan Chen Shu-Qing Tang Ting-Fang Yang guo-xiang he Department of Cardiology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina Department of Oncology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina

In this editorial,we review the article published in World J Gastrointest Oncol 2019,11:*** specifically focus on the occurrence,clinical characteristics,and risk factors of fluoropyrimidine drug-related cardiotoxicity in patients with gastrointestinal *** significant advancements in diagnostic and therapeutic techniques that have reduced mortality rates associated with digestive system tumors,the incidence and mortality rates of treatment-related car-diotoxicity have been increasing,severely impacting the survival and prognosis of cancer *** drugs are widely used as antimetabolites in the treatment of malignant tumors,including gastrointestinal tumors,and they represent the second largest class of drugs associated with ***,there is often a lack of awareness or understanding regarding their cardiotoxic effects and associated risks.

关键词： Cardiotoxicity Gastrointestinal tumors Risk factors Fluoropyrimidine Chest pain

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Practical approach for detecting k-nonseparability of multipartite quantum states

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 32-48页

作者： Jie guo Jinchuan Hou Xiaofei Qi Kan he College of Mathematics Taiyuan University of Technology School of Mathematics and Statistics Shanxi University Key Laboratory of Complex Systems and Data Science of Ministry of Education Shanxi University

The instantaneous detection of entanglement in quantum states poses a significant challenge in the fields of quantum computation and quantum information, and there are no practical methods or tools to complete this task satisfactorily so far. We propose a sufficient and necessary criterion of k-nonseparability for any n-partite finite or infinite dimensional systems, 2 ≤ k ≤ n. This criterion serves as the foundation for a practical scheme designed to detect entanglement and k-nonseparability across multipartite finite-dimensional systems. To exemplify the application of our scheme, we have developed a software tool that facilitates swift and precise identification of entanglement, k-nonseparability, and genuine entanglement within n-qubit systems, specifically tailored for systems with 2 ≤ n ≤ 4.

关键词： multipartite systems entanglement states entanglement witnesses ${\bm~k}$-nonseparability

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The SPECTRAL RADIUS OF UNIFORM HYPERGRAPH DETERMINED BY The SIGNLESS LAPLACIAN MATRIX

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数学杂志 2025年第1期45卷 1-12页

作者： he Fang-guo College of Mathematics and Statistics Huanggang Normal UniversityHuBei 438000

This paper studies the problem of the spectral radius of the uniform hypergraph determined by the signless Laplacian *** upper bound of the spectral radius of a uniform hypergraph is obtained by using Rayleigh principle and the perturbation of the spectral radius under moving the edge operation,and the extremal hypergraphs are characterized for both supertree and unicyclic *** spectral radius of the graph is generalized.

关键词： spectral radius uniform hypergraph Signless Laplasian matrix

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Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders:drug stability,targeting efficiency,and safety

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Neural Regeneration Research 2025年第7期20卷 1883-1899页

作者： Mingyu Zhang Chunyu xiang Renrui Niu Xiaodong he Wenqi Luo Wanguo Liu Rui Gu Department of Orthopedic Surgery China-Japan Union Hospital of Jilin UniversityChangchunJilin ProvinceChina

Various nanoparticle-based drug delivery systems for the treatment of neurological disorders have been widely ***,their inability to cross the blood–brain barrier hampers the clinical translation of these therapeutic *** are nanoparticles composed of lipid bilayers,which can effectively encapsulate drugs and improve drug delivery across the blood–brain barrier and into brain tissue through their targeting and ***,they can potentially treat traumatic and nontraumatic central nervous system *** this review,we outlined the common properties and preparation methods of liposomes,including thin-film hydration,reverse-phase evaporation,solvent injection techniques,detergent removal methods,and microfluidics ***,we comprehensively discussed the current applications of liposomes in central nervous system diseases,such as Alzheimer's disease,Parkinson's disease,Huntington's disease,amyotrophic lateral sclerosis,traumatic brain injury,spinal cord injury,and brain *** studies related to liposomes are still in the laboratory stage and have not yet entered clinical ***,their application as drug delivery systems in clinical practice faces challenges such as drug stability,targeting efficiency,and ***,we proposed development strategies related to liposomes to further promote their development in neurological disease research.

关键词： Alzheimer's disease amyotrophic lateral sclerosis brain tumors central nervous system Huntington's disease liposome drug delivery neurological disorders Parkinson's disease spinal cord injury traumatic brain injury

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2003-2004年麻醉药品管理分析

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岳阳职业技术学院学报 2005年第2期20卷 52-53页

作者：郭荷湘湖南省血防所湘岳医院湖南岳阳414000

本文对岳阳湘岳医院住院部2003-2004年麻醉药品(包括一类精神药品如盐酸布桂嗪注射液、盐酸麻黄碱注射液、盐酸氯胺酮注射液应按麻醉药品管理)共9种药品的用药数量、用药率、用药金额及处方情况进行统计分析,旨在了解麻醉药品的临床应... 详细信息

本文对岳阳湘岳医院住院部2003-2004年麻醉药品(包括一类精神药品如盐酸布桂嗪注射液、盐酸麻黄碱注射液、盐酸氯胺酮注射液应按麻醉药品管理)共9种药品的用药数量、用药率、用药金额及处方情况进行统计分析,旨在了解麻醉药品的临床应用情况和目前用药趋势。

关键词：麻醉药品用药频度管理分析 2003-2004年岳阳湘岳医院住院部用药数量用药金额

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Low‑Temperature Oxidation Induced Phase Evolution with Gradient Magnetic heterointerfaces for Superior Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第1期17卷 191-204页

作者： Zizhuang he Lingzi Shi Ran Sun Lianfei Ding Mukun he Jiaming Li Hua guo Tiande Gao Panbo Liu School of Chemistry and Chemical Engineering Northwestern Polytechnical UniversityXi’an 710129People’s Republic of China School of Marine Science and Technology Northwestern Polytechnical UniversityXi’an 710072People’s Republic of China

Gradient magnetic heterointerfaces have injected infinite vitality in optimizing impedance matching,adjusting dielectric/magnetic resonance and promoting electromagnetic(EM)wave absorption,but still exist a significant challenging in regulating local phase ***,accordion-shaped Co/Co_(3)O_(4)@N-doped carbon nanosheets(Co/Co_(3)O_(4)@NC)with gradient magnetic heterointerfaces have been fabricated via the cooperative high-temperature carbonization and lowtemperature oxidation *** results indicate that the surface epitaxial growth of crystal Co_(3)O_(4) domains on local Co nanoparticles realizes the adjustment of magnetic-heteroatomic components,which are beneficial for optimizing impedance matching and interfacial ***,gradient magnetic heterointerfaces simultaneously realize magnetic coupling,and long-range magnetic ***,the synthesized Co/Co_(3)O_(4)@NC absorbents display the strong electromagnetic wave attenuation capability of−53.5 dB at a thickness of 3.0 mm with an effective absorption bandwidth of 5.36 GHz,both are superior to those of single magnetic domains embedded in carbon *** design concept provides us an inspiration in optimizing interfacial polarization,regulating magnetic coupling and promoting electromagnetic wave absorption.

关键词： Magnetic heterointerfaces Phase evolution Interfacial polarization Magnetic coupling Electromagnetic wave absorption

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Multiple Tin Compounds Modified Carbon Fibers to Construct heterogeneous Interfaces for Corrosion Prevention and Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第1期17卷 507-527页

作者： Zhiqiang guo Di Lan Zirui Jia Zhenguo Gao Xuetao Shi Mukun he Hua guo Guanglei Wu Pengfei Yin College of Science Sichuan Agricultural UniversityYa’an 625014People’s Republic of China School of Materials Science and Engineering Hubei University of Automotive TechnologyShiyan 442002People’s Republic of China Institute of Materials for Energy and Environment State Key Laboratory of Bio‑Fibers and Eco‑TextilesCollege of Materials Science and EngineeringQingdao UniversityQingdao 266071People’s Republic of China Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China

Currently,the demand for electromagnetic wave(EMW)absorbing materials with specific functions and capable of withstanding harsh environments is becoming increasingly ***-component interface engineering is considered an effective means to achieve high-efficiency EMW ***,interface modulation engineering has not been fully discussed and has great potential in the field of EMW *** this study,multi-component tin compound fiber composites based on carbon fiber(CF)substrate were prepared by electrospinning,hydrothermal synthesis,and high-temperature thermal *** utilizing the different properties of different substances,rich heterogeneous interfaces are *** effectively promotes charge transfer and enhances interfacial polarization and conduction *** prepared SnS/SnS_(2)/SnO_(2)/CF composites with abundant heterogeneous interfaces have and exhibit excellent EMW absorption properties at a loading of 50 wt%in epoxy *** minimum reflection loss(RL)is−46.74 dB and the maximum effective absorption bandwidth is 5.28 ***,SnS/SnS_(2)/SnO_(2)/CF epoxy composite coatings exhibited long-term corrosion resistance on Q235 steel ***,this study provides an effective strategy for the design of high-efficiency EMW absorbing materials in complex and harsh environments.

关键词： Electrostatic spinning Component regulation heterogeneous interfaces Electromagnetic wave absorption Corrosion protection

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