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Fine needle aspirating and cutting is superior to Tru-cut core needle in liver biopsy

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Hepatobiliary & Pancreatic Diseases International 2013年第5期12卷 508-511页

作者： guo-ping li Gao-Quan Gong Xiao-lin Wang Yi Chen Jie-Min Cheng Chang-Yu li Department of Interventional Radiology Zhongshan HospitalFudan University

BACKGROUND:liver biopsy is the "gold standard" for evaluating liver disorders,but controversies over the potential risk of complications and patient discomfort still *** a 21G fine needle,we developed a new biopsy procedure,fine needle aspirating and cutting(FNAC).Our procedure obtains enough tissue for pathological examination and meanwhile,reduces the risk of biopsy *** present study was to determine the safety and efficiency of 21G FNAC compared with 18G Tru-cut core needle(TCN) in liver tumor ***:Ninety-four patients with unresectable malignant tumors were included in this *** were divided into 2 groups:18G TCN and 21G *** total positive rate(TPR) and safety of both groups were ***:TPR was not different between the two *** puncture track subcapsular hemorrhage and arteriovenous shunt were reported with 18G TCN but not with 21G *** incidence of pain caused by biopsy was higher for the 18G TCN group compared to the 21G FNAC group(P0.5 cm,but 52.1% in the 21G FNAC group(P<0.05).More than 50% of patients in both groups had sufficient tissue for immunohistochemical ***:TPR is not different between the 21G FNAC and 18G TCN biopsy procedures,but the safety of 21G FNAC is superior to that of 18G *** obtained by either of these two procedures are sufficient for a pathological diagnosis.

关键词： biopsy tumor chemoembolization diagnostic liver

Optical appearance of the Schwarzschild black hole in the string cloud context

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Chinese Physics C 2023年第6期47卷 199-208页

作者：郭森黄宇翔李国平 Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China School of Physics and Astronomy China West Normal UniversityNanchong 637000China

The image of a black hole(BH)consists of direct and secondary images that depend on the observer *** investigate the optical appearance of a Schwarzschild BH in the context of a string cloud to reveal how the BH’s observable characteristics are influenced by the inclination angle,string cloud parameter,and impact *** Luminet’s work[***.75,228(1979)],we adopt a semi-analytic method to calculate the total bending angle of the light ray and derive the direct and secondary images of the Schwarzschild string cloud *** results show that an increase in the inclination angle leads to a more pronounced separation of the *** consider the gravitational redshift and present the redshift distribution of the direct image while illustrating the flux *** observe that the direct image exhibits blueshift and redshift simultaneously,and the asymmetry of the flux distribution increases with the inclination ***,we obtain the Schwarzschild string cloud BH image via a numerical simulation,which provides an approximate illustration of the EHT resolution.

关键词： black hole optical appearance thin disk accretion

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Observational appearance and extra photon rings of an asymmetric thin-shell wormhole with a Bardeen profile

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Chinese Physics C 2024年第6期48卷 211-221页

作者：何柯腱罗智郭森李国平 Department of Physics Chongqing UniversityChongqing 401331China Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China School of Physics and Astronomy China West Normal UniversityNanchong 637000China

In this work,the optical appearance of an asymmetric thin-shell wormhole with a Bardeen profile is *** initiate the process,we need to construct an asymmetric thin-shell wormhole utilizing the cut-and-paste technique proposed by Visser and subsequently ascertain its pertinent physical quantities such as the radius of the photon sphere and critical impact parameters for different values of magnetic charge ***,the effective potential and motion behavior of photons are also investigated within the framework of asymmetric thin-shell wormholes with a Bardeen *** can be found that the effective potential,ray trajectory,and azimuthal angle of the thin-shell wormhole exhibit a strong correlation with the mass ratio of black *** considering the accretion disk as the sole background light source,we observe additional photon rings and lensing bands in the optical appearance of the asymmetric thin-shell wormhole with a Bardeen profile compared to those exhibited by the Bardeen black *** can find that there is an increase in the size of the specific additional light bands with increasing magnetic charge g,which is different from the black hole *** exceptionally luminous rings can serve as a robust criterion for the identification and characterization of the thin-shell wormhole spacetime.

关键词： shadow asymmetric thin-shell wormhole Bardeen black hole

Transcriptional Regulation of Urokinase Receptor in High-(95D) and Low-metastatic (95C) Human Lung Cancer Cells

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Acta Biochimica et Biophysica Sinica 2004年第6期36卷 405-411页

作者： Chun-Yang li, li TAN, guo-Jing ZHANG, ping li, Chang TONG, Jing FAN, and Yun-Song ZHU* Key Laboratory, the Education Ministry, Department of Biochemistry and Molecular Biology, Shanghai Medical College,Fudan University, Shanghai 200032, China Key Laboratory the Education Ministry Department of Biochemistry and Molecular Biology Shanghai Medical College Fudan UniversityShanghai 200032 China

To study the transcriptional regulation of urokinase receptor (uPAR) in high- (95D) and low-metastatic (95C) human lung cancer cells, we performed PCR to amplify 2238 bp uPAR promoter from 95C and 95D cells. According to the results of sequencing, five different bases are found in uPAR promoter between 95C and 95D cells. The results of luciferase activity assay showed that these differences have no significant effect on the uPAR promoter activity. Based on a normal uPAR promoter, progressive truncated mutants were constructed. The transient transfection/reporter assay showed that the promoter region from –136 to +9 may interact with relevant nuclear factors, which result in different levels of uPAR expression between 95C and 95D cells.

关键词： uPAR promoter transcriptional regulation

Shadow thermodynamics of AdS black hole with the nonlinear electrodynamics term

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Chinese Physics B 2023年第8期32卷 201-208页

作者：郑何斌牟平辉陈芸仙李国平 School of Physics and Astronomy China West Normal UniversityNanchong 637000China

We creatively employ the shadow radius to study the thermodynamics of a charged Ad S black hole with a nonlinear electrodynamics(NLED)***,the connection between the shadow radius and event horizon is constructed with the aid of the geodesic *** turns out that the black hole shadow radius shows a positive correlation as a function of the event horizon *** in the shadow context,we find that the black hole temperature and heat capacity can be presented by the shadow *** analysis shows that the shadow radius can work similarly to the event horizon in revealing black hole phase transition *** this sense,we construct the thermal profile of the charged Ad S black hole with inclusion of the NLED *** the P

关键词： AdS black hole the nonlinear electrodynamics shadow thermodynamics

Additional observational features of the thin-shell wormhole by considering quantum corrections

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Chinese Physics C 2024年第12期48卷 200-211页

作者： Yun-Xian Chen He-Bin Zheng Ke-Jian He guo-ping li Qing-Quan Jiang Physics and Space College China West Normal UniversityNanchong 637000China School of Civil Engineering Chongqing Jiaotong University 400074China

By considering an asymmetric thin-shell wormhole(ATSW)surrounded by an optically and geometrically thin disk,we investigate the luminosity distribution of this ATSW with the spacetime on two sides encoded with the renormalization group improved(RGI)parameters(Ω,γ).Although some light rays are absorbed into the throat in the vicinity of the wormhole,they return through the throat with certain conditions,unlike in the case of black *** spacetime on one side of the wormhole can capture the additional photons emitted from the thin disk,resulting in several interesting observable features of the *** results in this paper show that there are two additional orbit numbers n in the ATSW and six transfer functions,rather than three as in the black hole *** this case,the ATSW indeed has a more complex observable structure,where some additional light rings arise *** instance,there are two additional photon rings for the emitted Model ***,we also find a new wide hump between the first and second additional photon rings in Model *** effects of Ω and γ on the observed images are clearly addressed throughout this study,and the influence of Ω is found to be ***,we conclude that the observations of the RGI-ATSW can help further distinguish it from other ATSWs and black holes when a thin accretion disk exists around it.

关键词： additional observational features thin-shell wormhole photon rings quantum corrections

sPLA2-IB Level Correlates with Hyperlipidemia and the Prognosis of Idiopathic Membranous Nephropathy

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Current Medical Science 2020年第4期40卷 683-690页

作者： li-yan YANG Yuan-sheng WU Bin-bin DAI Song-hua liN Hong CHEN guo-ping li Xuan TAO Jian-xin WAN Yang-bin PAN Department of Nephrology the First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005China Shanghai Pudong Hospital Fudan University Pudong Medical CenterShanghai 201399China Department of Cardiology the First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005China Department of Pathology the First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005China

Summary:Recent studies suggested that serum secretory phospholipase A2 group IB(sPLA2-IB)was increased in idiopathic membranous nephropathy(IMN).However,the interference of high lipemia on the sPL.A2-IB levels was not taken into account in these *** present study aimed to investigate the correlation between sPLA2-IB and lipemia,and the clinical merit of sPLA2-IB in the prediction of prognosis of IMN patients.A total of 64 IMN patients,39 immunoglobulin A nephropathy(IgAN)patients and 64 healthy controls were included in the *** levels of serum sPLA2-IB,lipemia and proteinuria were *** IMN patients were followed up for 6 *** stages were made for all IgAN and IMN *** results showed that the levels of serum sPLA2-IB,cholesterol and low-density lipoprotein cholesterol(LDL-C)were significantly higher,and the levels of albumin and high-density lipoprotein cholesterol(HDL-C)were significantly lower in IMN patients than in healthy controls and IgAN *** sPLA2-IB levels were also found to be higher in IgAN patients than in heathy controls,but the association of serum sPLA2-IB levels with proteinuria,cholesterol and albumin was only shown in IMN *** against M-type receptor for secretory phospholipase A2(PLA2R1)was positive in 813%IMN *** sPLA2-IB deposition,podocyte fused processes,and density deposition on thickened basement membrane were seen in IMN patients,but not in IgAN *** patients with lower sPLA2-IB and proteinuria levels were found to have better outcome after the 6-month *** IMN patients,sPLA2-IB levels were significantly increased in both serum and renal *** conclusion,serum sPLA2-IB was closely correlated with proteinuria,albumin and cholesterol,and IMN patients with lower sPLA2-IB levels were more likely to achieve a better outcome.

关键词： sPLA2-IB lipemia idiopathic membranous nephropathy prognosis

Triple points and phase transitions of D-dimensional dyonic Ad S black holes with quasitopological electromagnetism in Einstein–Gauss–Bonnet gravity

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Chinese Physics B 2024年第6期33卷 272-287页

作者：牟平辉蒋青权何柯腱李国平 School of Physics and Astronomy China West Normal UniversityNanchong 637000China College of Physics Chongqing UniversityChongqing 401331China

By considering the negative cosmological constant Λ as a thermodynamic pressure, we study the thermodynamics and phase transitions of the D-dimensional dyonic Ad S black holes(BHs) with quasitopological electromagnetism in Einstein–Gauss–Bonnet(EGB) gravity. The results indicate that the small/large BH phase transition that is similar to the van der Waals(vdW) liquid/gas phase transition always exists for any spacetime dimensions. Interestingly, we then find that this BH system exhibits a more complex phase structure in 6-dimensional case that is missed in other ***, it shows for D = 6 that we observed the small/intermediate/large BH phase transitions in a specific parameter region with the triple point naturally appeared. Moreover, when the magnetic charge turned off, we still observed the small/intermediate/large BH phase transitions and triple point only in 6-dimensional spacetime, which is consistent with the previous results. However, for the dyonic Ad S BHs with quasitopological electromagnetism in Einstein–Born–Infeld(EBI) gravity, the novel phase structure composed of two separate coexistence curves observed by li et al. [Phys. Rev. D105 104048(2022)] disappeared in EGB gravity. This implies that this novel phase structure is closely related to gravity theories, and seems to have nothing to do with the effect of quasitopological electromagnetism. In addition, it is also true that the critical exponents calculated near the critical points possess identical values as mean field theory. Finally, we conclude that these findings shall provide some deep insights into the intriguing thermodynamic properties of the dyonic Ad S BHs with quasitopological electromagnetism in EGB gravity.

关键词： AdS black hole phase transition triple point

Efficacy of laser peripheral iridoplasty and iridotomy on medically refractory patients with acute primary angle closure： a three year outcome

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Chinese Medical Journal 2013年第1期126卷 41-45页

作者： FU Jing QING guo-ping WANG Ning-li WANG Huai-zhou Beijing Tongren Eye Center Beijing Tongren Hospital CapitalMedical University Beijing Ophthalmology & Visual SciencesKey Laboratory Beijing 100730 China

Background Argon laser peripheral iridoplasty （ALPI） is proved to be effective in lowering intraocular pressure （lOP） of patients with mild acute primary angle closure （APAC）. It is unclear whether this laser treatment is equally efficient in managing patients with severe APAC. This study aimed peripheral iridotomy （LPI） on patients with refractory APAC, therapy. to evaluate the IOP-lowering efficacy of ALPI and laser who have previously responded poorly to intensive medical Methods Thirty-six patients （8 men and 28 women） were identified as medically refractory APAC, who still had ocular pain, red eye, hazy cornea, closed anterior chamber （AC） angle, and lOP of not less than 21 mmHg after two days or more of anti-glaucoma medication. All enrolled patients underwent ophthalmologic examinations including measurement of visual acuity （VA）, best corrected VA （BCVA）, lOP, biomicroscopy, and gonioscopy followed by ALPI immediately in the APAC eye and LPI in both eyes. Results All patients were affected unilaterally, with average age of （54.6±11.7）（range, 37.0-75.0） years old. The mean lOP value of the affected eyes dropped from （31.6±7.7）（range, 21.0-39.0） mmHg at enrollment to （18.4±8.7）（range, 10.0-27.0） mmHg 2 hours after ALPI. At follow-up day 7, the mean lOP value maintained at （14.8±4.2）（range, 9.0-21.0） mmHg, which was significantly different （P=0.000） compared with baseline. The average decrease of lOP in the APAC eyes was （16.8±7.4）（range, 12.0-21.0） mmHg. At follow-up three years later, the mean lOP of the APAC eyes stabilized at （16.3±3.2）（range, 9.0-20.0） mmHg with at least 180° of AC angle opened. Conclusion ALPI and LPI lower the lOP of medically refractory cases of APAC though they have responded poorly to anti-glaucoma medication.

关键词： glaucoma acute primary angle closure argon laser peripheral iridoplasty laser peripheral iridotomy management