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International Journal of Oral Science 2009年第4期1卷 217-223页

作者： Quan Yu Xiao-gang Pan guo-ping Ji Gang shen Shanghai Key Laboratory of Stomatology Department of Orthodontics Shanghai Ninth People＇s Hospital Affiliated toShanghai Jiao Tong University School of Medicine Shanghai China

Aim To investigate the relationship between the positioning of the lower central incisor and physical morphology of the surrounding alveolar bone. Methodology Thirty-eight patients （18 males, 20 females）, with mean age of 13.4 years, were included in this study. As part of orthodontic treatment planning the patients were required to take dental Cone-beam CT （CBCT） covering the region of lower incisors, the sur- rounding alveolar bone and the mandibular symphysis. The cephalometric parameters were designed and measured to indicate the inclination of lower central incisor and physical morphology of the adjacent alveolar bone. Computer-aided descriptive statistical analysis was performed using SPSS 15.0 software package for Windows. A correlation analysis and a linear regression analysis between the incisor inclination and the alveolar bone morphology were performed. Results Significant positive correlations were found between the lower central incisor inclination and the morphological contour of the alveolar bone （P〈0.05）. The lower central incisor root apex was closer to the lingual alveolar crest when it was buccally inclined. Conclusion The morphology of the alveolar bone may be affected by incisal inclination.

关键词： Cone-beam CT (CBCT) alveolar bone incisorinclination

Ni(OH)_(2) Derived from NiS_(2) Induced by Reflux Playing Three Roles for Hydrogen/Oxygen Evolution Reaction

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Chinese Journal of Structural Chemistry 2022年第8期41卷 52-57页

作者： sheng-Jun Xu Ya-Nan Zhou guo-ping shen Bin Dong Dongying Haike Ruilin Chemical Co. LTD.Dongying 257000China State Key Laboratory of Heavy Oil Processing College of Chemistry and Chemical EngineeringChina University of Petroleum(East China)Qingdao 266580China

Developing efficient and promising non-noble catalysts for oxygen evolution reaction(OER) and hydrogen evolution reaction(HER) is vital but still a huge challenge for the clean energy system. Herein, we have integrated the active components for OER(Ni(OH)_(2)) and HER(Ni S_(2) and Ni(OH)_(2)) into Ni(OH)_(2)@NiS_(2) heterostructures by a facile reflux method. The in-situ formed Ni(OH)_(2) thin layer is coated on the surface of hollow Ni S2 nanosphere. The uniform Ni(OH)_(2)@NiS_(2) hollow sphere processes enlarge the electrochemically active specific surface area and enhance the intrinsic activity compared to NiS_(2) precursor, which affords a current density of 10 m A cm^(-2) at the overpotential of 309 m V and 100 m Acm^(-2) at 359 m V for OER. Meanwhile, Ni(OH)_(2)@NiS_(2) can reach 10 m A cm^(-2) at 233 m V for HER, superior to pure NiS_(2). The enhanced performance can be attributed to the synergy between Ni(OH)_(2) and NiS_(2). Specifically, Ni(OH)_(2) has three functions for water splitting: providing active sites for hydrogen adsorption and hydroxyl group desorption and working as real OER active sites. Moreover, Ni(OH)_(2)@NiS_(2) displays great stability for OER(50 h) and HER(30 h).

关键词： Ni(OH)_(2) NiS_(2) heterostructures oxygen evolution reaction hydrogen evolution reaction

Isothermal oxidation behavior and mechanism of a nickel-based superalloy at 1000°C

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International Journal of Minerals,Metallurgy and Materials 2017年第7期24卷 776-783页

作者： Zhi-yuan Zhu Yuan-fei Cai You-jun Gong guo-ping shen Yu-guo Tu guo-fu Zhang School of Material Science and Engineering Jiangsu University of Science and Technology Technology Center Jiangsu Shenyuan Special Steel Co.Ltd

The oxidation behavior of a nickel-based superalloy at 1000°C in air was investigated through X-ray diffraction, scanning electron microscopy, and energy-dispersive spectroscopy analysis. A series of oxides, including external oxide scales（Cr_2O_3,（TiO_2 ＋ Mn Cr_2O_4）） and internal oxides（Al_2O_3,Ti N）, were formed on the surface or sub-surface of the substrate at 1000°C in experimental still air. The oxidation resistance of the alloy was dependent on the stability of the surface oxide layer. The continuity and density of the protective Cr_2O_3 scale were affected by minor alloying elements such as Ti and Mn. The outermost oxide scale was composed of TiO_2 rutile and Mn Cr_2O_4 spinel, and the growth of TiO_2 particles was controlled by the outer diffusion of Ti ions through the pre-existing oxide layer. Severe internal oxidation occurred beneath the external oxide scale, consuming Al and Ti of the strength phase γ′（Ni_3（Al,Ti）） and thereby severely deteriorating the surface mechanical properties. The depth of the internal oxidation region was approximately 35 μm after exposure to experimental air at 1000°C for 80 h.

关键词： nickel-based superalloy isothermal oxidation oxide scale internal oxidation

Correlation of Skp2 overexpression to prognosis of patients with nasopharyngeal carcinoma from South China

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Chinese Journal of Cancer 2011年第3期30卷 204-212页

作者： Hui-Min Xu Yi Liang Qiong Chen Qi-Nian Wu Yun-Miao guo guo-ping shen Ru-Hua Zhang Zhi-Wei He Yi-Xin Zeng Fang-Yun Xie Tie-Bang Kang State Key Laboratory of Oncology in South China Guangzhou Guangdong 510060 P. R. China Department of Radiation Oncology Sun Yat-sen University Cancer Center Guangzhou Guangdong 510060 P. R. China Department of Experimental Research Sun Yat-sen University Cancer Center Guangzhou Guangdong 510060 P. R. China Department of Pathology Sun Yat-sen University Cancer Center Guangzhou Guangdong 510060 P. R. China iuangdong Medical College Cancer Center Dongguan Guangdong 523808 P. R. China.

S-phase kinase-associated protein 2 (Skp2), which plays a role in cell cycle regulation, is commonly overexpressed in a variety of human cancers and associated with poor prognosis. However, its role in nasopharyngeal carcinoma (NPC) is not well understood. In this study, we examined the clinical significance of Skp2, with a particular emphasis on overall survival (OS) and disease-free survival (DFS), in NPC cases in South China, where NPC is an epidemic. Additionally, we explored the function of Skp2 in maintaining a cancer stem cell -like phenotype in NPC cell lines. Skp2 expression was assessed for 127 NPC patients using tissue microarrays and immunohistochemistry and analyzed together with clinicopathologic features, OS, and DFS. Skp2 expression was detectable, or positive, in 75.6% of patients. Although there was no correlation between Skp2 and any clinicopathologic factor, Skp2 expression significantly portended inferior OS (P = 0.013) and DFS (P = 0.012). In the multivariate model, Skp2 expression remained significantly predictive of poor OS [P = 0.009, risk ratio (RR) = 4.06] and DFS (P = 0.008, RR = 3.56), and this was also true for clinical stage (P = 0.012 and RR=3.201 for OS; P = 0.002 and RR=1.94 for DFS) and sex (P = 0.016 and RR=0.31 for OS; P = 0.006 and RR = 0.27 for DFS). After Skp2 knockdown, a colony formation assay was used to evaluate the self-renewal property of stem-like cells in the NPC cell lines CNE-1 and CNE-2. The colony formation efficiency in CNE-1 and CNE-2 cells was decreased. In Skp2-transfected CNE-1 and CNE-2 cells, side population (SP) proportion was increased as detected by flow cytometry. Skp2 is an independent prognostic marker for OS and DFS in NPC. Skp2 may play a role in maintaining the cancer stem cell-like phenotype of NPC cell lines.

关键词： Skp2 蛋白表达鼻咽癌预后患者中国全国人民代表大会细胞周期调控

A Rapid Adaptation Approach for Dynamic Air‑Writing Recognition Using Wearable Wristbands with Self‑Supervised Contrastive Learning

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Nano-Micro Letters 2025年第2期17卷 417-431页

作者： Yunjian guo Kunpeng Li Wei Yue Nam‑Young Kim Yang Li guozhen shen Jong‑Chul Lee Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897South Korea Radio Frequency Integrated Circuit(RFIC)Bio Centre Kwangwoon UniversitySeoul 01897South Korea Department of Electronic Engineering Kwangwoon UniversitySeoul 01897South Korea School of Microelectronics Shandong UniversityJinan 250101People’s Republic of China State Key Laboratory of Integrated Chips and Systems Fudan UniversityShanghai 200433People’s Republic of China School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081People’s Republic of China

Wearable wristband systems leverage deep learning to revolutionize hand gesture recognition in daily *** existing approaches that often focus on static gestures and require extensive labeled data,the proposed wearable wristband with selfsupervised contrastive learning excels at dynamic motion tracking and adapts rapidly across multiple *** features a four-channel sensing array composed of an ionic hydrogel with hierarchical microcone structures and ultrathin flexible electrodes,resulting in high-sensitivity capacitance *** wireless transmission from a Wi-Fi module,the proposed algorithm learns latent features from the unlabeled signals of random wrist ***,only few-shot labeled data are sufficient for fine-tuning the model,enabling rapid adaptation to various *** system achieves a high accuracy of 94.9%in different scenarios,including the prediction of eight-direction commands,and air-writing of all numbers and *** proposed method facilitates smooth transitions between multiple tasks without the need for modifying the structure or undergoing extensive task-specific *** utility has been further extended to enhance human–machine interaction over digital platforms,such as game controls,calculators,and three-language login systems,offering users a natural and intuitive way of communication.

关键词： Wearable wristband Self-supervised contrastive learning Dynamic gesture Air-writing Human-machine interaction

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根管治疗期间急症的发生原因和处理

上海口腔医学 2003年第5期12卷 328-330页

作者：周建国沈海平沈燕浙江省海盐县人民医院口腔科浙江海盐314300

目的探讨根管治疗期间急症的发生原因及其治疗方法。方法对55例根管治疗期间急症的患牙进行临床分析。用地塞米松和甲硝唑行根管内封药,1周后用Vitapex糊剂加牙胶尖行根管充填;术后随访1a,评价其疗效。结果根管治疗期间急症的发生率为12... 详细信息

目的探讨根管治疗期间急症的发生原因及其治疗方法。方法对55例根管治疗期间急症的患牙进行临床分析。用地塞米松和甲硝唑行根管内封药,1周后用Vitapex糊剂加牙胶尖行根管充填;术后随访1a,评价其疗效。结果根管治疗期间急症的发生率为12.59%(55/437)。牙髓炎组(5.13%)与牙髓坏死、根尖周炎组(16.73%)的急症发生率差异有显著性(P<0.01),前牙组与后牙组发生率差异有显著性(P<0.01)。随访1年时疗效评定为成功者达92.7%。结论根管治疗期间急症的发生与术前患牙的牙髓状况、牙位等有关;用地塞米松和甲硝唑行根管内封药及用Vitapex糊剂加牙胶尖行根管充填治疗,效果可靠。

关键词：根管治疗急症甲硝唑地塞米松充填

Remaining Life Prediction Method for Photovoltaic Modules Based on Two-Stage Wiener Process

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Energy Engineering 2025年第1期122卷 331-347页

作者： Jie Lin Hongchi shen Tingting Pei Yan Wu School of Electrical Engineering and Information Engineering Lanzhou University of TechnologyLanzhou730050China

Photovoltaic (PV) modules, as essential components of solar power generation systems, significantly influence unitpower generation *** service life of these modules directly affects these costs. Over time, the performanceof PV modules gradually declines due to internal degradation and external environmental *** cumulativedegradation impacts the overall reliability of photovoltaic power generation. This study addresses the complexdegradation process of PV modules by developing a two-stage Wiener process model. This approach accountsfor the distinct phases of degradation resulting from module aging and environmental influences. A powerdegradation model based on the two-stage Wiener process is constructed to describe individual differences inmodule degradation processes. To estimate the model parameters, a combination of the Expectation-Maximization(EM) algorithm and the Bayesian method is employed. Furthermore, the Schwarz Information Criterion (SIC) isutilized to identify critical change points in PV module degradation trajectories. To validate the universality andeffectiveness of the proposed method, a comparative analysis is conducted against other established life predictiontechniques for PV modules.

关键词： Photovoltaic modules degradation stochastic processes lifetime prediction

Optimizing Fine-Tuning in Quantized Language Models:An In-Depth Analysis of Key Variables

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Computers, Materials & Continua 2025年第1期82卷 307-325页

作者： Ao shen Zhiquan Lai Dongsheng Li Xiaoyu Hu National Key Laboratory of Parallel and Distributed Computing National University of Defense TechnologyChangsha410073China Strategic Assessments and Consultation Institute Academy of Military ScienceBeijing100091China

Large-scale Language Models(LLMs)have achieved significant breakthroughs in Natural Language Processing(NLP),driven by the pre-training and fine-tuning *** this approach allows models to specialize in specific tasks with reduced training costs,the substantial memory requirements during fine-tuning present a barrier to broader ***-Efficient Fine-Tuning(PEFT)techniques,such as Low-Rank Adaptation(LoRA),and parameter quantization methods have emerged as solutions to address these challenges by optimizing memory usage and computational *** these,QLoRA,which combines PEFT and quantization,has demonstrated notable success in reducing memory footprints during fine-tuning,prompting the development of various QLoRA *** these advancements,the quantitative impact of key variables on the fine-tuning performance of quantized LLMs remains *** study presents a comprehensive analysis of these key variables,focusing on their influence across different layer types and depths within LLM *** investigation uncovers several critical findings:(1)Larger layers,such as MLP layers,can maintain performance despite reductions in adapter rank,while smaller layers,like self-attention layers,aremore sensitive to such changes;(2)The effectiveness of balancing factors depends more on specific values rather than layer type or depth;(3)In quantization-aware fine-tuning,larger layers can effectively utilize smaller adapters,whereas smaller layers struggle to do *** insights suggest that layer type is a more significant determinant of fine-tuning success than layer depth when optimizing quantized ***,for the same discount of trainable parameters,reducing the trainable parameters in a larger layer is more effective in preserving fine-tuning accuracy than in a smaller *** study provides valuable guidance for more efficient fine-tuning strategies and opens avenues for further research into optimizing LLM

关键词： Large-scale Language Model Parameter-Efficient Fine-Tuning parameter quantization key variable trainable parameters experimental analysis

Syntheses and Crystal Structures of a New Triaryltriazole Ligand and Its Iron（Ⅱ） Complex

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Syntheses and Crystal Structures of a New Triaryltriazole Li...

Estimation of Chloride Diffusivity in Hydrated Tricalcium Silicate Using a Hydration-Diffusion Integrated Method

中国化学会第六届全国结构化学学术会议

作者： guo-ping shen,Lei Wang,Xiao-Qin Liu,Dun-Ru Zhu~* College of Chemistry and Chemical Engineering,State Key Laboratory of Materials-oriented Chemical Engineering,Nanjing University of Technology,Nanjing, 210009,P.R.China

＜正＞Over the past few decades,the substituted 1,2,4-triazoles have been reported to show a variety of pharmacological activities such as anti-inflammatory,antitumor,fungicide,weedicide and so ***, substituted 1,2,4-triazoles also have attracted considerable attention in coordination chemistry due to their rich and versatile coordination ***,some iron（Ⅱ） complexes containing substituted

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 49-64页

作者： WANG Xin shen Dejian TAO Sijie LIU Ruixin WU shengxing College of Civil and Transportation Engineering Hohai UniversityNanjing 210098China

This study aims to develop a chloride diffusion simulation method that considers the hydration microstructure and pore solution properties during the hydration of tricalcium silicate(C3S).The method combines the hydration simulation,thermodynamic calculation,and finite element analysis to examine the effects of pore solution,including effect of electrochemical potential,effect of chemical activity,and effect of mechanical interactions between ions,on the chloride effective diffusion coefficient of hydrated C3S *** results indicate that the effect of electrochemical potential on chloride diffusion becomes stronger with increasing hydration age due to the increase in the content of hydrated calcium silicate;as the hydration age increases,the effect of chemical activity on chloride diffusion weakens when the number of diffusible elements decreases;the effect of mechanical interactions between ions on chloride diffusion decreases with the increase of hydration age.

关键词： tricalcium silicate simulation method chloride diffusion coefficient pore solution