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Pulp health and calcific healing of a complicated crown–root fracture with additional root fracture in a maxillary incisor: A case report

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World Journal of Clinical Cases 2025年第3期13卷 42-49页

作者： Na Li Yue-Yue Ren Ying Tang Qi yang Tian-Tian Meng Song Li jing Zhang Stomatological Hospital and College Anhui Medical UniversityHefei 230032Anhui ProvinceChina Department of Endodontics The Affiliated Stomatological Hospital of Xuzhou Medical UniversityXuzhou 221000Jiangsu ProvinceChina

BACKGROUND Complicated crown–root fracture (CRF) involves severe injury to the crown, root,and pulp, and may be accompanied by multiple root fractures. The loss of a toothhas lifelong consequences for children and teenagers, but the maintenance of pulphealth and the calcific healing of multiple root fractures are rarely reported in *** SUMMARY This case reports healing of a permanent tooth with complicated crown–root andadditional root fractures, in which pulp health was maintained. A 10-year-old girlfell and fractured the root of her maxillary left central incisor at the cervical *** the coronal fragment was repositioned, the tooth was splinted until thetooth was no longer mobile, 2 years later. Eight years after treatment, the toothhas remained asymptomatic with vital pulp and localized gingival ***-beam computed tomography revealed not only calcified healing of the CRFbut also spontaneous healing in an additional undiagnosed root fracture. Thefracture line on the enamel could not be healed by hard tissue and formed agroove in the cervical crown. It was speculated that the groove was related to thelocalized gingival *** This case provides a clinical perspective of the treatment of a tooth with acomplicated CRF and an additional root fracture.

关键词： Complicated crown-root fracture Multiple root fracture Spontaneous healing Cone-beam computed tomography Long-term follow-up Case report

Sine oculis homeobox homolog family function in gastrointestinal cancer:Progression and comprehensive analysis

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World Journal of Clinical Oncology 2025年第1期16卷 10-24页

作者： yang-Zheng Lan Zheng Wu Wen-Jia Chen Xin-Ning Yu Hua-Tao Wu jing Liu Department of The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The sine oculis homeobox homolog(SIX)family,a group of transcription factors characterized by a conserved DNA-binding homology domain,plays a critical role in orchestrating embryonic development and organogenesis across various organisms,including *** six distinct members,from SIX1 to SIX6,each member contributes uniquely to the development and differentiation of diverse tissues and organs,underscoring the versatility of the SIX *** or mutations in SIX genes have been implicated in a spectrum of developmental disorders,as well as in tumor initiation and progression,highlighting their pivotal role in maintaining normal developmental trajectories and cellular *** to target the transcriptional complex of the SIX gene family have emerged as a promising strategy to inhibit tumor *** the development of inhibitors targeting this gene family is still in its early stages,the significant potential of such interventions holds promise for future therapeutic ***,this review aimed to comprehensively explore the advancements in understanding the SIX family within gastrointestinal cancers,focusing on its critical role in normal organ development and its implications in gastrointestinal cancers,including gastric,pancreatic,colorectal cancer,and hepatocellular *** conclusion,this review deepened the understanding of the functional roles of the SIX family and explored the potential of utilizing this gene family for the diagnosis,prognosis,and treatment of gastrointestinal cancers.

关键词： Sine oculis homeobox homolog Gastrointestinal cancer Transcription factor Development Regulation Diagnosis Therapeutics

Anomalous quality factor evolution of induced transparency in a virtualized coupled-oscillator system

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 148-155页

作者： Yunhan yang Han Jia Tuo Liu Yuzhen yang Jun yang Key Laboratory of Noise and Vibration Research Institute of Acoustics Chinese Academy of Sciences University of Chinese Academy of Sciences State Key Laboratory of Acoustics Institute of Acoustics Chinese Academy of Sciences

The phenomenon of induced transparency, characterized by a high quality(Q) factor, holds significant importance in the fields of high-precision sensing, energy storage and wave manipulation. Conventional transparency systems are often constrained by the limited experimentally accessible parameter space and the lack of independent control over intrinsic parameters, thereby hindering advanced research on high-Q effects. Here we propose a virtualized coupled-oscillator system that enables reconfigurable induced transparency in the reflection spectrum. By virtually incorporating a pair of coupled oscillators into an individual acoustic meta-atom, we achieve the manipulation of induced transparency in a decoupled, wide-ranging, and elaborate manner. Exploiting the diverse evolutions across the intrinsic parameter space, we show experimentally a counter-intuitive increase in the Q-factor of the transparency window, which is attributed to the enhanced dissipation of the bright ***, a constant group delay at the center frequency is observed accompanying this evolution. Our work demonstrates an intriguing platform as well as a novel strategy to engineer high-Q induced transparency phenomenon, and paves the way towards applications in programmable acoustic sensors, filters and slow-wave devices.

关键词： induced transparency acoustic meta-atom high quality-factor scattering programmable intrinsic parameter

沼肥/钙镁磷肥对土壤-菠菜中重金属Cd的影响

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沈阳农业大学学报 2023年第5期54卷 572-578页

作者：李轶张轩轩郭敬阳崔铁浩荣方舟谷士艳沈阳农业大学工程学院沈阳110161

土壤重金属污染已威胁到人类的健康和生命安全,而重金属的危害与其赋存形态密切相关。沼肥是一种优质的有机肥,其对土壤重金属形态的影响鲜有研究。以菠菜为种植作物,通过盆栽试验,每盆添加土样为1 kg,设置不施肥、施加沼肥和施加沼肥+... 详细信息

土壤重金属污染已威胁到人类的健康和生命安全,而重金属的危害与其赋存形态密切相关。沼肥是一种优质的有机肥,其对土壤重金属形态的影响鲜有研究。以菠菜为种植作物,通过盆栽试验,每盆添加土样为1 kg,设置不施肥、施加沼肥和施加沼肥+钙镁磷肥3组处理,每组处理重复5次,钝化剂钙镁磷肥添加比例为5 g·(kg干土)-1。研究施加沼肥及沼肥+钙镁磷肥对土壤及菠菜中重金属Cd的影响及其钝化机理。结果表明:试验后各处理土壤中水溶态、可交换态Cd比例均降低,而残渣态比例升高;施加沼肥或沼肥+钙镁磷肥能够提高重金属Cd的钝化效果,且沼肥+钙镁磷肥重金属Cd钝化效果优于施加沼肥。菠菜不同部位重金属Cd的富集程度为根>茎>叶,施加沼肥+钙镁磷肥时菠菜根茎叶中重金属含量最少。试验前土壤重金属Cd主要与富里酸(fulvic acid,FA)结合,试验后各处理与胡敏酸(humic acid,HA)结合的比例显著增加(p<0.05);添加沼肥+钙镁磷肥处理的HACd所占比例高于添加沼肥处理或不施肥处理。傅里叶红外光谱(fourier transform infrared spectrometer,FTIR)表明施加沼肥处理及施加沼肥+钙镁磷肥处理与不施肥处理的土壤中碳水化合物、蛋白质、糖类等有机物相比所占比例减少,而芳香族等腐殖质所占比例增加;土壤中施加沼肥+钙镁磷肥处理腐殖化程度更好。因此,土壤中施加沼肥或钙镁磷肥可在一定程度上减少重金属污染风险,而且沼肥+钙镁磷肥的效果优于单独施用沼肥。研究结果为沼肥利用及土壤重金属污染治理提供了科学的理论数据。

关键词：土壤沼肥钙镁磷肥 Cd 红外光谱

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Literature study on traditional Chinese medicine syndromes after renal transplantation

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World Journal of Transplantation 2025年第1期15卷 150-155页

作者： Yun-Peng guo Ling-Xue Bao Yu-yang Wang Quan Wen Gai Hang Bo Chen Tongliao Clinical Medical College Inner Mongolia Medical UniversityTongliao 028000Inner Mongolia Autonomous RegionChina Department of Urology Tongliao People's HospitalTongliao 028000Inner Mongolia Autonomous RegionChina

BACKGROUND Kidney transplantation is the most effective means to treat patients with renal failure,but its postoperative problems such as rejection reactions,immunosuppressant poisoning,chronic transplant kidney nephropathy,*** have not been effectively *** study searched for literature on traditional Chinese medicine(TCM)syndromes after kidney transplantation in China,conducted statistical analysis of the results,and sought to identify the underlying *** To understand the TCM syndromes after renal transplantation and associated rules and provide a theoretical basis for further clinical *** The literature pertaining to TCM syndromes in renal transplantation,published in the China National Knowledge Infrastructure,Wanfang database,and WIP database from 1970 to 2021,was meticulously searched and comprehensively and statistically *** Following the established inclusion and exclusion criteria,13 studies were selected for ***-renal transplantation,no significant discrepancy was noted among the groups based on the location of TCM ***,when categorized according to TCM pathogenic factors,the groups with spleen and kidney yang deficiency,as well as liver and kidney yin deficiency,exhibited a statistically significant difference in the *** Currently,the research on TCM syndromes pertaining to renal transplantation is in its nascent *** is imperative to conduct a multicentric,large-scale survey of TCM syndromes subsequent to renal transplantation in the ensuing years.

关键词： Kidney transplantation Syndrome Literature analysis Traditional Chinese medicine Systematic review

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妇科肿瘤患者术后医院感染相关因素分析

中华医院感染学杂志 2017年第4期27卷 896-898,922页

作者：卢慧陈红晓郭景霞杨莉莉袁梦岚天津市第五中心医院妇产科天津300450

目的分析妇科肿瘤患者术后感染的危险因素,为降低妇科肿瘤术后感染提供依据。方法选取2013年2月-2016年4月入院的妇科肿瘤患者122例,回顾性分析术后患者感染的部位、不同部位感染率及导致感染的危险因素。结果 122例患者中术后感染24例... 详细信息

目的分析妇科肿瘤患者术后感染的危险因素,为降低妇科肿瘤术后感染提供依据。方法选取2013年2月-2016年4月入院的妇科肿瘤患者122例,回顾性分析术后患者感染的部位、不同部位感染率及导致感染的危险因素。结果 122例患者中术后感染24例,感染率为19.67%,其中泌尿道感染12例占50.00%,呼吸道感染6例占25.00%,生殖道感染3例占12.50%,手术切口感染2例占8.33%,胃肠道感染1例占4.17%;年龄>60岁、手术持续时间>2h、合并糖尿病、开放式手术、术后未应用抗菌药物、术后留置导管的患者感染率分别为31.64%、38.64%、42.42%、26.67%、53.57%、24.18%,显著高于年龄≤60岁、手术持续时间≤2h、不合并糖尿病、腹腔镜手术、术后应用抗菌药物、不留置导管的患者感染率(14.94%、8.97%、11.24%、8.51%、9.57%、6.45%),差异有统计学意义(P<0.05)。结论年龄偏大、手术持续时间过长、合并糖尿病、开放式手术、术后不应用抗菌药物和术后留置导管均是导致妇科肿瘤患者术后感染的重要危险因素。

关键词：妇科肿瘤患者术后感染危险因素

The molecular mechanism of plasma membrane H^(+)-ATPases in plant responses to abiotic stress

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Journal of Genetics and Genomics 2022年第8期49卷 715-725页

作者： jing Li Yan guo Yongqing yang Beijing Advanced Innovation Center for Tree Breeding by Molecular Design College of Bioscience and Resources EnvironmentBeijing University of AgricultureBeijing 102206China State Key Laboratory of Plant Physiology and Biochemistry College of Biological SciencesChina Agricultural UniversityBeijing 100193China

Plasma membrane H^(+)-ATPases(PM H^(+)-ATPases)are critical proton pumps that export protons from the cytoplasm to the *** resulting proton gradient and difference in electrical potential energize various secondary active transport *** H^(+)-ATPases play essential roles in plant growth,development,and stress *** this review,we focus on recent studies of the mechanism of PM H^(+)-ATPases in response to abiotic stresses in plants,such as salt and high pH,temperature,drought,light,macronutrient deficiency,acidic soil and aluminum stress,as well as heavy metal ***,we discuss remaining outstanding questions about how PM H^(+)-ATPases contribute to abiotic stress responses.

关键词： PM H^(+)-ATPases Abiotic stress Molecular mechanism

Asking one mechanism in glial cells during neuroinflammation

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Neural Regeneration Research 2025年第4期20卷 1077-1078页

作者： Xiaoli guo Chikako Harada Takayuki Harada Visual Research Project Tokyo Metropolitan Institute of Medical ScienceTokyoJapan

Multiple sclerosis(MS),which is characterized by inflammatory demyelination in the central nervous system(CNS),is the most common neurological disease in the young adult *** autoimmune encephalomyelitis(EAE),an animal model of MS,is often used in preclinical *** data indicate that in addition to immune cells such as T cells and dendritic cells,CNS resident microglia and astrocytes play important roles in demyelinating neuroinflammation(Healy et al.,2022).In particular,microglia are key immune-competent cells that can respond to environmental *** depletion of transforming growth factor-β-activated kinase 1,a mitogen-associated protein kinase kinase kinase,in microglia is reported to reduce CNS inflammation and diminish axonal and myelin damage *** suggests that elucidating the mechanisms of microglia-specific responses during pathologies may help in the development of treatments that reduce EAE/MS disease severity(Goldmann et al.,2013).

关键词： inflammation clinical

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鸭细小病毒地高辛标记探针的制备与应用

中国兽医学报 2016年第12期36卷 2001-2004页

作者：郑肖强陈浩窦砚国杨晶牛晓宇于相龙刁有祥山东农业大学动物科技学院山东泰安271018

根据GenBank发表的1株鸭细小病毒全基因组序列设计1对特异性引物,利用PCR扩增得到大小为301bp的片段,回收纯化后用地高辛进行标记,制备鸭细小病毒地高辛标记探针。特异性试验表明,该探针仅与鸭细小病毒发生特异性杂交反应,与GPV、MDPV、... 详细信息

根据GenBank发表的1株鸭细小病毒全基因组序列设计1对特异性引物,利用PCR扩增得到大小为301bp的片段,回收纯化后用地高辛进行标记,制备鸭细小病毒地高辛标记探针。特异性试验表明,该探针仅与鸭细小病毒发生特异性杂交反应,与GPV、MDPV、DcuV、DEV、DHAV-I、H9N2亚型AIV、N-DRV、NDV、TMUV杂交反应均为阴性。敏感性试验表明,该探针对鸭细小病毒核酸的最低检测量为25pg。应用制备的探针对山东、江苏和安徽等地采集的61份患病鸭和30份健康鸭组织进行检测,阳性率分别为97%和0%,与病毒分离结果符合率为98%。上述结果显示,本研究制备的探针特异性强、敏感性高,为该病的诊断和流行病学调查提供可靠的方法。

关键词：鸭细小病毒地高辛探针