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Pancreatic encephalopathy and Wernicke encephalopathy in association with acute pancreatitis: A clinical study

World Journal of Gastroenterology 2006年第26期12卷 4224-4227页

作者： guo-hui sun Yun-Sheng Yang Qing-Sen Liu Liu-Fang Cheng Xu-Sheng Huang Department of Gastroenterology Chinese PLA General Hospital Beijing 100853 China Department of Neurology Chinese PLA General Hospital Beijing 100853 China

AIM： To investigate clinical characteristics and therapy of pancreatic encephalopathy （PE） and Wernicke encephalopathy （WE）. METHODS： In a retrospective study of 596 patients with acute pancreatitis （AP）, patients with PE were compared to those with WE in regards to history, clinical manifestation, diagnosis, treatment and outcome. RESULTS： There were 93 patients with severe acute pancreatitis （SAP）. Encephalopathies were discovered in 10 patients （1.7%）. Six patients with PE all developed in SAP （6.5%）, and three of them died （3% of SAP, 50% of PE）. Four patients with WE developed in AP （0.7%）, and two of them died （0.3% of AP, 50% of WE）. Two patients with WE were treated with parenteral thiamine and survived. Global confusions were seen in all patients with encephalopathy. Ocular abnormalities were found. Conjugate gaze palsies were seen in 1 of 6 （16.7%） patients with PE. Of 4 patients with WE, one （25%） had conjugate gaze palsies, two （50%） had horizontal nystagmus, three （75%） had diplopia, and one （25%） had myosis. Ataxia was not seen in all patients. None of patients with WE presented with the classic clinical triad. CSF examinations for 2 patients with WE showed lightlyincreased proteins and glucose. CT and MRI of the brain had no evidence of characteristic abnormalities. CONCLUSION： PE occurs in early or reiteration stage of SAP, and WE in restoration stage of SAP/AP. Ocular abnormalities are the hallmarks of WE, and horizontal nystagmus is common. It is difficult to diagnose earlier an encephalopathy as PE or WE, as well as differentiate one from the other. Long fasting, hyperemesis and total enteral nutrition （TPN） without thiamine are main causes of thiamine deficiency in the course of pancreatitis.

关键词： Pancreatic encephalopathy Wernicke encephalopathy Acute pancreatitis Thiamine Total parenteral nutrition

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YNi_5 PHASE AND ITS EFFECT UPON PROPERTIES OF Ni_3Al ALLOY

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Acta Metallurgica Sinica(English Letters) 1992年第3期5卷 183-187页

作者： WANG Shuhe guo Jianting LI hui sun Chao TAN Minghui LAI Wanhui Institute of Metal Research,Academia Sinica,Shenyang,China Inst of Metal Research Acad Sinica Shenyang China

An additive of Y to Ni_3Al based alloy may form a phase YNi_5 which increases in amount with the increase of Y *** was found that the YNi_5 phase in Ni_3Al alloy could remarkably make its grains finer and its grain boundaries more crooked other than *** the Y con- tent≥0.1 wt-%,it occurs as solid solution state and is favorable to high temperature compressive properties and oxidation resistance of the *** Y≥0.3 wt-%,the forma- tion of YNi_5 is predominant in the shape of irregular strips inside Ni_3Al grains and along their grain *** seems to be quite harmful to high temperature strength,ductility and oxidation resistance of the alloy.

关键词： Ni_3Al YNi_5 phase Y compressive property oxidation resistance

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EFFECT OF Zr,Cr AND B ADDITIVES ON MICROSTRUCTURE AND MECHANICAL PROPERTIES OF Ni_3Al ALLOYS

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Acta Metallurgica Sinica(English Letters) 1990年第3期3卷 170-176页

作者： guo Jianting LI hui sun Chao ZHU Yaoxiao Institute of Metal Research,Academia Sinica,Shenyang,China guo Jianting,Professor,Institute of Metal Research,Academia Sinica,Shenyang 110015,China

The microstructure and the mechanical properties from room temperature up to 1050℃ of Ni_3Al alloys containing 0—0.6 at.-%Zr,0—7.7 at.-%Cr and 0—2.22 at.-%B have been *** was found that the temperature dependence of their yield strength variation reveals to be anomalous,*** strength increases with the temperature raising,and then decreases till it surpassed the peak *** Zr and Zr+Cr may improve the yield strength of the al- loys in the entire range of testing temperatures,as well as the tensile strength and elongation under high temperatures.B is favourable to raise the tensile and yield strengths of the alloys, and also *** the strength will reduce as B added is over 2.22 at.-%.The Ni_(20)Al_3B_6 and Ni_3Al eutectic mixture like islands and globes precipitated inside the grains and along the grain bounderies,which are harmful to the strength and ductility,may be formed when the B content exceeds the limit of solubility.

关键词： Ni_3Al microstructure mechanical property yield strength

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A NUMERICAL STUDY ON VORTEX RINGS WITH SWIRL

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Journal of Hydrodynamics 2001年第2期13卷 1-8页

作者： Hu guo hui, sun De jun, Yin Xie yuan Department of Modern Mechanics, University of Science and Technology of China, Hefei 230026 , China

A finite difference scheme in cylindrical coordinates was used to study the three dimensional (3D) motion of a vortex ring with swirl and the passage interaction between two vortex rings. For the 3D evolution of a single thin ring, the azimuthal perturbation modes grow linearly in the early stage. According to their growth rates, two bands of growing waves, which correspond to the first and the second radial mode respectively, can be observed. The result is similar to the prediction of short wave instability theory for swirl free vortex rings. For the passage process between two rings, results show that the azimuthal velocity is in inverse proportion to radius while the azimuthal vorticity is in proportion to radius during the interaction.

关键词： vortex ring with swirl leap frogging direct numerical simulation

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鲁比扬卡的彩屏:布哈林最后的哲学

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内蒙古大学学报（哲学社会科学版） 2007年第3期39卷 121-124页

作者：孙国徽内蒙古工业大学人文与社会科学学院内蒙古呼和浩特010051

布哈林在生命的最后一年里在鲁比扬卡监狱里的哲学著述《哲学彩屏(辩证法概述)》一书,论述了他对真理正义的追求。布哈林这部最后的哲学手稿不但内容广博,而且充满了布哈林最后生命的光彩和对马克思主义哲学的最新奉献。正如俄罗斯哲学... 详细信息

布哈林在生命的最后一年里在鲁比扬卡监狱里的哲学著述《哲学彩屏(辩证法概述)》一书,论述了他对真理正义的追求。布哈林这部最后的哲学手稿不但内容广博,而且充满了布哈林最后生命的光彩和对马克思主义哲学的最新奉献。正如俄罗斯哲学家奥古尔佐夫评价的:“布哈林的手稿是创立另一种非斯大林式的马克思主义哲学的最后一次尝试”。

关键词：布哈林哲学彩屏鲁比扬卡

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Plasmonic tandem heterojunctions enable high-efficiency charge transfer for broad spectrum photocatalytic hydrogen production

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Journal of Energy Chemistry 2025年第1期100卷 710-720页

作者： Wenxuan Chen Xiu-Qing Qiao guo hui Bojing sun Dongfang Hou Meidi Wang Xueqian Wu Tao Wu Dong-Sheng Li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University Hubei Three Gorges Laboratory College of Chemistry and Materials Science and Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry Jinan University

Rational engineering of semiconductor photocatalysts for efficient hydrogen production is of great significance but still challenging,primarily due to the limitations in charge transfer ***,a fascinating plasmonic tandem heterojunction with the hc-CdS/Mo2C@C heterostructure is aimfully prepared for effectively promoting the charge separation kinetics of the CdS photocatalyst via the synergistic strategy of phase junction,Schottky junction,and photothermal *** difference in atomic configuration between cubic-CdS （c-CdS） and hexagonal-CdS （h-CdS） leads to effective charge separation through a typical Ⅱ charge transfer mechanism,and plasmonic Schottky junction further extracts the electrons in the hc-CdS phase junction to realize gradient charge ***,the photothermal effect of Mo2C@C helps to expand the light absorption,accelerate charge transfer kinetics,and reduce the hydrogen evolution energy *** carbon layer provides a fast channel for charge transfer and protects the photocatalyst from *** a result,the optimized hc-CMC photocatalyst exhibits a significantly high photocatalytic H2production activity of 28.63 mmol/g/h and apparent quantum efficiency of 61.8%,surpassing most of the reported *** study provides a feasible strategy to enhance the charge transfer kinetics and photocatalytic activity of CdS by constructing plasmonic tandem heterogeneous junctions.

关键词： Heterojunctions LSPR Photocatalyst Phase junction Schottky junction Photothermal effect

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Effect of tea polyphenols on cytochrome P450 and b5 content and mRNA expression of CYP2E1 and CYP1A2 in liver of mice

Effect of tea polyphenols on cytochrome P450 and b5 content ...

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第三届中日双边药理学和临床药理学学术会议

作者： CHEN Xia HAN guo-Zhu sun hui-Jun (Department of Pharmacology,Dalian Medical University,Dalian 116027,China)

AIM To investigate content of tea ployphe- nols(TPs) on cytochrome P450 and b5,and the expres- sion of CYP2E1 and CYP1A2 in livers of male mice re- ceiving *** ①Determination of the con- tent of TPs on eytochrome P450 and b5:TPs were injected intra-peritoneally to male mice at the doses of 25,50 and 100 mg·kg·d,respectively,for 2 *** positive control group was given chloramphenieol at a single dose of 50 mg·kg 1 h before sacrificing the *** negative control group was given the equal volume of saline solu- *** the contents of cytochrome P450 and b5 were determined by UV-spectrophotometry.②Determination of the expression of CYP2E1 and CYP1 A2:TPs were admin- istered intragastrically to male mice at the doses of 100, 200 and 400 mg·kg·d separatively for 5 *** model group and the negative control group were given the equal volume of saline *** the mice were given parac- etamol at the doses of 500 mg·kg at 1 h after TPs were administered last time except the mice in negative control ***2E1 and CYP1A2 mRNA expression levels in the liver were evaluated by *** The contents of cytochrome P450 and b5 in the livers of mice in three groups of TPs were dose-dependently decreased compared with the negative control *** CYP2E1 and CYP1 A2 mRNA expression levels of the TPs groups were dose-dependently decreased relative to the control group and the model *** TPs can suppress both cytochrome P450 and b5 in a dose depend- ent *** suppress cytochrome P450 isoform CYP2E1 and CYP1A2 mRNA *** results demonstrated that TPs defense paracetamol-induced liver damage by inhibiting mRNA expression of CYP2E1 and CYP1A2.

关键词： tea ployphenols CYP450 b5 CYP2E1 CYP1 A2 paracetamol

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薄孔壁厚和小孔径测量系统

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天津大学学报（自然科学与工程技术版） 2004年第10期37卷 914-917页

作者：李斐郭辉孙长库郑义忠张以谟天津大学精密测试技术与仪器国家重点实验室天津300072

由于相邻孔壁厚度的测量根据进刀量进行计算时精度很低,故提出了一种应用电容传感器对2个微小孔间相邻孔壁进行精密测量的系统.基于非接触式电容测孔传感器,研究了测头的电场边缘效应影响及保护环的宽度选择,设计了电容瞄准测孔传感器... 详细信息

由于相邻孔壁厚度的测量根据进刀量进行计算时精度很低,故提出了一种应用电容传感器对2个微小孔间相邻孔壁进行精密测量的系统.基于非接触式电容测孔传感器,研究了测头的电场边缘效应影响及保护环的宽度选择,设计了电容瞄准测孔传感器的测头对相邻小孔中心定位,利用电容差动测厚传感器测量孔壁.系统由1个瞄准测孔传感器和2个差动测厚传感器及三通道测量电路组成,处理数据后直接显示孔径和孔间壁厚.系统属非接触测量,无需修正测头及工件变形误差.实验证明,测量精度为0.5μm.

关键词：电容传感器非接触测量孔径孔壁

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Construction of Ni single-atom coordinated with doped N and S elements for mild hydrogenation of methyl acrylate to methyl propionate

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Nano Research 2025年第1期18卷 217-224页

作者： Taolue sun Chen Jian Gang Wang hui Zhao guoliang Zhang Zengxi Li Chunshan Li State Key Laboratory of Mesoscience and Engineering CAS Key Laboratory of Green Process and EngineeringBeijing Key Laboratory of Ionic Liquids Clean ProcessInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China huizhou Institute of Green Energy and Advanced Materials Huizhou 516081China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516081China

Although the nickel-based catalyst is able toexhibit comparative catalytic activity to noble metal formethyl acrylate hydrogenation,it requires strict reactioncondition,which can be improved by regulation ofcoordination *** this study,we constructed akind of Ni single-atom coordinated with N and S(Ni-NSC)through the pyrolysis of organic Ni-based precursors at600℃.The existence and fine structure of Ni single-atom were confirmed by the spherical electron microscopicobservation in combination with the X-ray absorption spectroscopy(XAS)*** addition,the catalytichydrogenation assessment suggested that the as-prepared Ni-NSC catalyst exhibited higher activity and stability than theNi/NSC supported catalyst prepared by incipient wetness impregnation *** remarkable catalytic activity was dueto the high dispersion and density of Ni single-atom and weak adsorption energy of intermediates on these Ni sites.

关键词： methyl acrylate mild hydrogenation Ni single-atom coordination environment adsorption energy

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Exosomes:the next-generation therapeutic platform for ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1221-1235页

作者： Wenjing Yin Hongyin Ma Yang Qu Jiaxin Ren Yingying sun Zhen-Ni guo Yi Yang Stroke Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina Neuroscience Research Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina

Current therapeutic strategies for ischemic stroke fall short of the desired objective of neurological functional ***,there is an urgent need to develop new methods for the treatment of this *** are natural cell-derived vesicles that mediate signal transduction between cells under physiological and pathological *** have low immunogenicity,good stability,high delivery efficiency,and the ability to cross the blood–brain *** physiological properties of exosomes have the potential to lead to new breakthroughs in the treatment of ischemic *** rapid development of nanotechnology has advanced the application of engineered exosomes,which can effectively improve targeting ability,enhance therapeutic efficacy,and minimize the dosages *** in technology have also driven clinical translational research on *** this review,we describe the therapeutic effects of exosomes and their positive roles in current treatment strategies for ischemic stroke,including their antiinflammation,anti-apoptosis,autophagy-regulation,angiogenesis,neurogenesis,and glial scar formation reduction ***,it is worth noting that,despite their significant therapeutic potential,there remains a dearth of standardized characterization methods and efficient isolation techniques capable of producing highly purified *** optimization strategies should prioritize the exploration of suitable isolation techniques and the establishment of unified workflows to effectively harness exosomes for diagnostic or therapeutic applications in ischemic ***,our review aims to summarize our understanding of exosome-based treatment prospects in ischemic stroke and foster innovative ideas for the development of exosome-based therapies.

关键词： blood–brain barrier electroacupuncture engineering exercise exosomes ischemic stroke mesenchymal stem cells microglia neuroprotection stents

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