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Serum cystatin C levels are negatively correlated with post-stroke cognitive dysfunction

Neural Regeneration Research 2020年第5期15卷 922-928页

作者： Dao-Xia guo Zheng-Bao Zhu Chong-Ke Zhong Xiao-Qing Bu Li-Hua Chen Tan Xu Li-Bing guo Jin-Tao Zhang Dong Li Jian-Hui Zhang Zhong Ju Chung-Shiuan Chen Jing Chen Yong-Hong Zhang jiang He Department of Epidemiology School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric DiseasesMedical College of Soochow UniversitySuzhouJiangsu ProvinceChina Department of Epidemiology Tulane University School of Public Health and Tropical MedicineNew OrleansLAUSA Department of Neurology Siping Central HospitalSipingJilin ProvinceChina Department of Neurology the 88th Hospital of People’s Liberation ArmyTaianShandong ProvinceChina Department of Internal Medicine Feicheng City People’s HospitalFeichengShandong ProvinceChina Department of Neurology Tongliao Municipal HospitalInner Mongolia Autonomous RegionChina Department of Neurology Kerqin District First People’s Hospital of Tongliao CityInner Mongolia Autonomous RegionChina Department of Medicine Tulane University School of MedicineNew OrleansLAUSA

Stroke is the leading cause of death and long-term disability worldwide,and cognitive impairment and dementia are major complications of ischemic *** C (CysC) has been found to be a neuroprotective factor in animal ***,the relationship between CysC levels and cognitive dysfunction in previous studies has revealed different *** prospective observational study investigated the correlation between serum CysC levels and post-stroke cognitive dysfunction at 3 *** from 638 patients were obtained from the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS).Cognitive dysfunction was assessed using the Mini-Mental State Examination (MMSE) at 3 months after *** to the MMSE score,308 patients (52.9%) had post-stroke cognitive *** adjusting for potential confounding factors,the odds ratio (95% CI) of post-stroke cognitive dysfunction for the highest quartile of serum CysC levels was 0.54 (0.30–0.98),compared with the lowest *** correlation between serum CysC and cognitive dysfunction was modified by renal function *** observed a negative linear dose-response correlation between CysC and cognitive dysfunction in patients with normal renal function (Plinearity = 0.044),but not in those with abnormal renal *** serum CysC levels were correlated with a low risk of 3-month cognitive dysfunction in patients with acute ischemic stroke,especially in those with normal renal *** current results suggest that CysC is a protective factor for post-stroke cognitive dysfunction,and could be used to treat post-stroke cognitive *** CATIS study was approved by the Institutional Review Boards at Soochow University from China (approval No.2012-02) on December 30,2012,and was registered at *** (identifier ***01840072) on April 25,2013.

关键词： abnormal renal function cognitive dysfunction cystatin C ischemic stroke Mini-Mental State Examination neural regeneration neuroprotective effect normal renal function

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跨流域调水生态环境影响评价指标体系研究

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水利学报 2008年第9期39卷 1125-1130,1135页

作者：郭潇方国华章哲恺河海大学水利水电工程学院浙江省水利水电勘测设计院浙江杭州310009

目前对跨流域调水工程生态环境影响评价,尚未构建一套普遍适用的指标体系。在对工程实例进行充分调研的基础上,从跨流域调水对水源区、输水区和受水区的生态环境影响特征出发,遵循系统性、代表性、科学性、定性定量相结合、独立性和客... 详细信息

目前对跨流域调水工程生态环境影响评价,尚未构建一套普遍适用的指标体系。在对工程实例进行充分调研的基础上,从跨流域调水对水源区、输水区和受水区的生态环境影响特征出发,遵循系统性、代表性、科学性、定性定量相结合、独立性和客观性等原则,从物理化学系统、生物系统、社会经济系统三方面分别构建跨流域调水的生态环境影响评价指标体系。并针对解决城市供水、农业灌溉、生态环境保护和综合开发利用等不同目标的跨流域调水工程在环境影响评价指标权重分配上所体现的差异进行了分析总结,可供跨流域调水对生态环境影响评价时参考选用。

关键词：跨流域调水生态环境影响评价指标体系

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铁路隧道内列车发生火灾时通风临界时间的确定

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中国铁道科学 2018年第4期39卷 101-106页

作者：姜学鹏张鹏郭辉武汉科技大学资源与环境工程学院湖北武汉430081 武汉科技大学湖北省工业安全工程技术研究中心湖北武汉430081 武汉科技大学消防安全技术研究所湖北武汉430081 中铁第四勘察设计院集团有限公司建筑与城市规划设计研究院湖北武汉430063

采用数值模拟方法获得隧道纵向通风排烟模式下的可用安全疏散时间,并与采用Togawa经验公式计算的所需安全疏散时间进行对比,以此判断人员疏散安全性,分析确定通风临界时间。结果表明:隧道纵向通风排烟下,通风开始时间对人员疏散安全性... 详细信息

采用数值模拟方法获得隧道纵向通风排烟模式下的可用安全疏散时间,并与采用Togawa经验公式计算的所需安全疏散时间进行对比,以此判断人员疏散安全性,分析确定通风临界时间。结果表明:隧道纵向通风排烟下,通风开始时间对人员疏散安全性影响显著。通风开始时间早于180s人员疏散不安全;当火源功率不大于15MW时,通风开始时间不早于180s即可保证人员安全疏散,而火源功率大于15MW时,通风开始时间不早于180s且不晚于240s才能保证人员安全疏散;当纵向通风风速大于3m·s^(-1)时,通风开始时间不早于180s即可保证人员安全疏散,而纵向通风风速不大于3m·s^(-1)时,通风开始时间不早于180s且不晚于300s才能保证人员安全疏散。综合得出铁路隧道内列车发生火灾时通风临界时间为180s。

关键词：铁路隧道列车火灾通风排烟通风临界时间火灾救援

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Sedimentary lithofacies characteristics and sweet-spot interval characterization of the Sinian Doushantuo Formation in Upper Yangtze Platform, South China

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China Geology 2019年第3期2卷 261-275页

作者： Yu-fang Wang Gang-yi Zhai Yong-chao Lu Yi-quan Ma Juan Li guo-heng Liu Yun-xiao Zhang Oil and Gas Survey China Geological SurveyMinistry of Natural ResourcesBeijing 100083China Unconventional Oil and Gas Geology Laboratory China Geological SurveyMinistry of Natural ResourcesBeijing 100083China China University of Geosciences Wuhan 430074China

The Sinian Doushantuo Formation is the oldest shale gas reservoir discovered in the world, which contains good shale gas shows as the Eyangye-1 and Zidi-1 wells in the Yichang Region of western Hubei province, China. The shales in the Doushantuo Formation feature considerable thickness (135 m), high gas content (4.83 m^3/t) and high fragile mineral content (up to 75%). Due to the influences of the sedimentary environment, the shale reservoirs here have high dolomitic content (54%) and abruptly changes in vertical lithofacies. Moreover, the characteristics of the shale sweet-spot differ significantly from that in the Wufeng Formation and Longmaxi Formation in southeast Sichuan Basin. A high-resolution sequence stratigraphic correlation was performed on the shales of the Doushantuo Formation at the Eyangye-1 well, Zidi-1 well, Zidi-2 well and some outcrop profiles in Yichang area for the identification of their sedimentary microfacies characteristics. A comprehensive comparative analysis was made by incorporating the elemental geochemistry, wireline and mud logging data of the well to further identify the sweet-spot interval therein. With the analysis of Eyangye-1 well, the sweet-spot interval of the Doushantuo Formation is 3360?3408 m, of which sedimentary microfacies is deepwater reduced environment with many pyrite laminaes, and the TOC is high to 3.42%, the Ro is 3.3%, the organic and matrix pore are well developed and the aperture more than 50 nm, the porosity is 2.7%, the desorption gas content average is 2.16%, and the main mineral is dolomitic (54%) and siliceous quartz (21%). Additionally, these parameters combined with previous studies will shed light on evaluating and characterizing the layers therein, also provide referential geological data for the following exploration and development activities of this shale system.

关键词： Shale gas Sequence correlation Sweet-spot interval Doushantuo Formation (Late Proterozoic) Upper Yangtze Platform Oil and gas exploration engineering Hubei Province China

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Ruminal in situ disappearance kinetics of six nutritive ingredients in leaves and stems of young tetraploid black locust in growing steers

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Forestry Studies in China 2009年第3期11卷 168-173页

作者： jiang Jin-zhong SUN Peng LI Yun ZHANG guo-jun LIU Jian-hua HAN Feng-bao NIU Chen College of Biological Sciences and Biotechnology Beijing Forestry University Key Laboratory of Genetics and Breeding of Forest Trees and Ornamental Plants of Ministry of Education Beijing 100083 P. R. China Department of Chemistry Guizhou Normal College Guiyang 550018 P. R. China Forestry Bureau of Xianghe County Hebei Province Xianghe 065400 P. R. China Department of Plant and Soil Science Texas Tech University Lubbock 79409 USA

Tetraploid black locust （Robinia pseudoacacia） is a woody plant with larger leaves and richer nutritional content than normal diploid black locust, with greater biomass and wider adaptability than herbaceous plant forage. However, currently no stock- breeders have adopted it as a major forage in China and other countries for a lack of information on the evaluation of nutritional ingredients of leaves and stems of young tetraploid black locust （YTBL） by in situ digesting tests. The objectives of this study were： 1） to assess the nutritive value of YTBL that bourgeoned from root stumps in the spring by determining the ruminal in situ disappearance kinetics of dry matter （DM）, organic matter （OM）, crude protein （CP）, ether extract （EE）, neutral detergent fiber （NDF） and acid detergent fiber （ADF） from leaves, stems and a mixture of both leaves and stems （MLS） of YTBL; 2） to compare these kinetic estimates with those of Leymus chinensis, a widely used ruminant forage in China. All samples were evaluated in situ by using five ruminally cannulated crossbred steers （550±22.7 kg BW）. The results of 48 hours, the representative incubation period, indicate that in situ disappearance rates of DM and OM in YTBL leaves, stems and MLS are on average about 40% and can attain the level of digestibility of L. chinensis. In situ disappearance rates of leaves, stems and MLS of YTBL for CP and EE were 41% and 58% respectively, rates higher than those of L. chinensis. But the disappearance rates of NDF and ADF were, on average, respectively 30.62% and 24.89% and lower than those ofL. chinensis. By analyzing synthetically all of our results it could be inferred that MLS of YTBL offers effective ruminal degradability of DM, NDF, ADF, CP, EE and OM, similar to the nutrients of L. chinensis. This supports our contention that the YTBL leaves, stems and MLS are suitable feed for those ruminants requiring high levels of nutrients, such as dairy cows and Boer goats, instead of plant forage, whi

关键词： tetraploid black locust in situ disappearance kinetics ruminant nutritive analyses

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基于真实性评价理论的职业教育课程思政育人效果评价体系构建

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职业技术教育 2022年第11期43卷 62-68页

作者：郭芳天津商务职业学院天津300350

对课程思政育人效果评价研究进行了文献梳理和述评,基于真实性评价理论,从评价目标、真实任务、评价标准、评价量规、评价反馈5个维度构建了职业教育课程思政育人效果评价体系。在评价目标上,该体系以“企业所需要的岗位能力和职业素养... 详细信息

对课程思政育人效果评价研究进行了文献梳理和述评,基于真实性评价理论,从评价目标、真实任务、评价标准、评价量规、评价反馈5个维度构建了职业教育课程思政育人效果评价体系。在评价目标上,该体系以“企业所需要的岗位能力和职业素养”为基准;在真实任务上,该体系以“企业真实工作情境”为导向;在评价标准上,该体系以“重参与、有深度、讲态度”为原则;在评价量规上,该体系以“规则透明、等级分明、榜样鲜明”为标准;在评价反馈上,该体系以“勤于思辩、动态调整”为宗旨。以电子商务专业为研究对象,对该体系进行了应用验证,结果证明该体系具有良好的育人效果。

关键词：真实性评价理论课程思政育人效果评价体系

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章学诚“六经皆史”说新论

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华东师范大学学报（哲学社会科学版） 2007年第6期39卷 52-57页

作者：蒋国保苏州大学哲学系苏州215021

对章学诚"六经皆史"说的含义,前辈学者已有种种的理解。通过梳理此说形成的过程,可以说明章氏晚年是从六经即政典的意义上断言"六经皆史"。这应该是他的定说。而他晚年的这一论断,乃由三个逻辑层次构成:(1)古代私人不著书,则传统以为经... 详细信息

对章学诚"六经皆史"说的含义,前辈学者已有种种的理解。通过梳理此说形成的过程,可以说明章氏晚年是从六经即政典的意义上断言"六经皆史"。这应该是他的定说。而他晚年的这一论断,乃由三个逻辑层次构成:(1)古代私人不著书,则传统以为经乃圣人孔子私人所著,不合乎历史事实;古人不曾脱离日常事情空谈义理,则传统以为经乃纯以文字言理之典籍,是没有根据的误解;(2)道不离器,理不离事,而事、器是指"先王制作",故"六经皆先王之政典";(3)政典即史,故"六经皆史"。

关键词：章学诚六经皆史政典史学

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张謇农业经济的思想和实践研究综述

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学术探索 2010年第1期 121-126页

作者：蒋国宏南通大学地方公共政策研究所江苏南通226019

关于张謇农业经济思想和实践的研究早在张謇在世之时即已开始,新中国成立后,因受"左"的思想困扰,研究一度陷于沉闷,20世纪80年代后重新焕发出生机。研究主要集中在张謇对农业地位的认识,张謇农业思想的内涵、来源及意义,张謇发展农业的... 详细信息

关于张謇农业经济思想和实践的研究早在张謇在世之时即已开始,新中国成立后,因受"左"的思想困扰,研究一度陷于沉闷,20世纪80年代后重新焕发出生机。研究主要集中在张謇对农业地位的认识,张謇农业思想的内涵、来源及意义,张謇发展农业的对策和举措,淮南盐垦公司的性质和地位,张謇在中国近代农业史上的地位等方面。当前,应打破学科壁垒,借助其他学科的知识、理论和方法,进行深度解读和重新审视,使对张謇农业经济思想和实践的研究跃上一个新的台阶。

关键词：张謇农业经济思想和实践研究综述

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Data processing and initial results of Chang'e-3 lunar penetrating radar

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Research in Astronomy and Astrophysics 2014年第12期14卷 1623-1632页

作者： Yan Su Guang-You fang Jian-Qing Feng Shu-guo Xing Yi-Cai Ji Bin Zhou Yun-Ze Gao Han Li Shun Dai Yuan Xiao Chun-Lai Li Key Laboratory of Lunar and Deep Space Exploration National Astronomical ObservatoriesChinese Academy of Sciences Institute of Electronics Chinese Academy of Sciences

To improve our understanding of the formation and evolution of the Moon, one of the payloads onboard the Chang＇e-3 （CE-3） rover is Lunar Penetrating Radar （LPR）. This investigation is the first attempt to explore the lunar subsurface structure by using ground penetrating radar with high resolution. We have probed the subsur- face to a depth of several hundred meters using LPR. In-orbit testing, data processing and the preliminary results are presented. These observations have revealed the con- figuration of regolith where the thickness of regolith varies from about 4 m to 6 m. In addition, one layer of lunar rock, which is about 330 m deep and might have been accumulated during the depositional hiatus of mare basalts, was detected.

关键词： space vehicles: instruments: Lunar Penetrating Radar -- techniques:radar astronomy -- methods: data processing -- Moon: lunar subsurface -- Moon:regolith

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DEHYDRATION AND FLUORIMETRIC DETERMINATION OF ADRIAMYCIN

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Chinese Chemical Letters 1992年第12期3卷 1001-1002页

作者： Yi Bzing ZHAO Xue fang MA Xiang Qun guo Jin Gou XU guo Zhen CHEN Department of Chemistry,Xiamen University,Xiamen 361005,CHINA

A dehydration reaction of ADM was carried out in sulfuric acid solution and an intensely fluorescent product was *** reaction was applied to the determination of ADM in body fluids.

关键词： ADH DEHYDRATION AND FLUORIMETRIC DETERMINATION OF ADRIAMYCIN

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