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Graft-verse-host disease after liver transplantation:A report of two cases and review of literature

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World Journal of Gastroenterology 2008年第6期14卷 974-979页

作者： Zhi-Yong guo Xiao-Shun He Lin-Wei Wu Xiao-Feng Zhu Wei-Qiang Ju dong-Ping wang Shen You Yi Ha guo-dong wang Jie-Fu Huang Organ Transplantation center First Affiliated Hospital Sun Yat-Scn University Guangzhou 510080 Guangdong Province China

Graft-verse-host disease (GVHD) is an uncommon fatal complication following liver transplantation (LTx). In China's Mainland, only six cases have been reported with a morbidity rate up to 1%-2%. Definitive diagnosis was achieved by molecular techniques (HLA typing or PCR-STR) in only two cases and the remaining cases were diagnosed based on typical clinical features with exclusion of other possible causes. All patients died of septic shock or multiple organ failure even after administration of increased corticosteroids and supportive therapy, and reduced immunosuppressive agents. In our center, two cases of GVHD were found among 128 (1.56%) patients. One case was diagnosed by detecting lymphocyte macrochimerism through DNA-STR. Both of them died even after aggressive treatment. In China, the incidence of GVHD is similar to that reported by foreign centers except for an extremely bad prognosis. Rapid diagnosis is crucial for a better prognosis. In China, only 37.5% of cases are diagnosed by molecular methods. We recommend detecting lymphocyte macrochimerism through DNA-STR to get a rapid diagnosis, and interleukin 2-receptor antibody (basiliximab or daclizumab) therapy seems to be a good choice for the disease.

关键词： Graft-versus-host disease Liver transplantation Prognosis Diagnosis Treatment

The geographical distribution of grey wolves (Canis lupus) in China:a systematic review

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Zoological Research 2016年第6期37卷 315-326页

作者： Lu wang Ya-Ping MA Qi-Jun ZHOU Ya-Ping ZHANG Peter SAVOLAINEN guo-dong wang State Key Laboratory for Conservation and Utilization of Bio-resources in Yunnan Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan ProvinceYunnan University State Key Laboratory of Genetic Resources and Evolution Yunnan Key Laboratory of Molecular Biology of Domestic AnimalsKunming Institute of ZoologyChinese Academy of Sciences Science for Life Laboratory Department of Gene TechnologyKTH-Royal Institute of Technology

The grey wolf （Canis lupus） is one of the most widely distributed terrestrial mammals, and its distribution and ecology in Europe and North America are largely well described. However, the distribution of grey wolves in southern China is still highly controversial. Several well-known western literatures stated that there were no grey wolves in southern China, while the presence of grey wolves across China has been indicated in A Guide to the Mammals of China, published by Princeton University Press. It is essential to solve this discrepancy since dogs may have originated from grey wolves in southern China. Therefore, we systematically investigated Chinese literatures about wild animal surveys and identified more than 100 articles and books that included information of the distribution of grey wolves in China. We also surveyed the collections of three Chinese natural museums and found 26 grey wolf skins specimens collected across China. Moreover, we investigated the fossil records in China and identified 25 archaeological sites with wolf remains including south China. In conclusion, with the comprehensive summary of Chinese literatures, museum specimens and fossil records, we demonstrate that grey wolves do distribute across all parts of the Chinese mainland, including the most southern parts.

关键词： China Grey wolf Distribution Conservation

Microstructure and Mechanical Properties of Precipitation Strengthened Fire Resistant Steel Containing High Nb and Low Mo

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Journal of Iron and Steel Research International 2015年第4期22卷 337-343页

作者： Zheng-yan ZHANG Qi-long YONG Xin-jun SUN Zhao-dong LI Jun-yu KANG guo-dong wang Department of Structural Steels Central Iron and Steel Research Institute State Key Laboratory of Rolling and Automation Northeastern University

Through the thermo-mechanical control process （TMCP）, a high Nb low Mo fire resistant steel with the yield strength （YS） of 521 MPa at room temperature （RT） and 360 MPa at elevated temperature （ET） of 600 ℃ was developed based on MX （M=Nb, V, Mo; X=C,N） precipitation strengthening. A series of tensile and con- stant load tests were conducted to study the mechanical properties at ET. The dynamic continuous cooling transfor- mation （CCT） as well as precipitation behavior of microalloy carbonitride was investigated by means of thermal sim- ulator and electron microscopy approaches. Results showed that the failure temperature of tested steel was deter- mined as 653 ℃, and the granular bainite was obtained when the cooling rate was higher than 10 ℃/s. In the rolled state, a certain amount of M/A islands was observed. During heating from RT to ET, M/A islands disappeared, and cementites and high dense compound precipitates （Nb, Mo, V）C with size of less than 10 nm precipitated in ferrite at ET （600 ℃）, which resulted in precipitation strengthening at ET.

关键词： fire resistant steel elevated temperature property microalloying granular bainite precipitation strengthening

Influence of Finishing Cooling Temperature and Holding Time on Nanometer-size Carbide of Nb-Ti Microalloyed Steel

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Journal of Iron and Steel Research International 2014年第4期21卷 433-438页

作者： Hai-long YI Yang XU Ming-xue SUN Zhen-yu LIU guo-dong wang State Key Laboratory of Rolling and Automation Northeastern University

The nanometer-size carbides formed in ferrite matrix of Nb-Ti microalloyed steel at different finishing cooling temperatures and holding time have been investigated. The characteristics of nanometer-size carbides in ferrite were observed by transmission electron microscopy, and mechanical properties of ferrite were detected by a nano-hardness tester. The results showed that interphase precipitation and diffusion precipitation were observed at different finishing cooling temperatures, and the interphase precipitation was planar and curved. Sheet spacing of inter-phase precipitation increased with the increase of finishing cooling temperature and changed a little when holding for 50--1000 s. Interphase precipitation shows higher nano-hardness at 640℃ compared with diffusion precipitation at 600℃, and the contribution of interphase precipitation to the mechanical properties of ferrite was larger than that of diffusion precipitation.

关键词： nanometer-size arbide Nb-Ti microalloyed steel interphase precipitation diffusion precipitation

Ligament augmentation reconstruction system artificial ligaments in patellar tendon reconstruction-a chronic patellar tendon rupture after multiple operations: A case report

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World Journal of Clinical Cases 2020年第4期8卷 831-837页

作者： Fei Yang guo-dong wang Rong Huang Hui Ma Xiao-Wei Zhao School of Clinical Medicine Jining Medical UniversityJining 272067Shandong ProvinceChina Department of Orthopedics The Affiliated Hospital of Jining Medical UniversityJining 272000Shandong ProvinceChina

BACKGROUND Patellar tendon rupture is a rare disease,and reports regarding patellar tendon reconstruction with ligament augmentation reconstruction system(LARS)ligaments are limited,with only three reports available in the *** ligaments are made of polyethylene terephthalate and have been certified as a more favorable option than other tendon *** our knowledge,this is the first report of patellar tendon reconstruction with LARS for suture fixation due to poor quality of the tendon after multiple operations to enable early mobilization and quick *** SUMMARY A 65-year-old woman had limited ability in extending her leg and an inability to perform a straight leg raise after multiple operations due to patella *** patient underwent patellar tendon reconstruction with LARS artificial *** 12 mo of follow-up,the patient was able to perform a straight leg raise,and the incision healed well without *** Lysholmscore was 95 and the range of motion of the knee was 0-130°.CONCLUSION This study revealed that patellar tendon reconstruction with LARS artificial ligaments is possible in a patient with a patellar tendon rupture who required rapid postoperative recovery.

关键词： Ligament augmentation reconstruction system artificial ligaments Patellar tendon Reconstruction Rupture Case report

Solidification microstructure of high borated stainless steels with rare earth and titanium additions

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Rare Metals 2020年第12期39卷 1483-1491页

作者： Yong-wang Li Hai-Tao Liu Zhao-Jie wang Zhi-Heng Zhang Wei-Ting Li Hui-Ying Shen Xiao-Ming Zhang guo-dong wang State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China

To study the effects of rare earth(RE)and Ti on the solidification micros true ture of high borated stainless steels,1.6 wt%B stainless steel doped with RE and2.1 wt%B stainless steel doped with Ti were prepared by ingot casting,*** solidification microstructure of researched steels was characterized in *** modification mechanism was clarified based on the heterogeneous nucleation theory and the thermodynamic *** solidification microstructure of 1.6 wt%B and 2.1 wt%B stainless steels was characterized by the continuous and network-like eutectic borides around the matrix *** was found that the fine RE compounds could act as the heterogeneous nuclei for both borides and austenite during ***,the eutectic borides were more dispersed in the modified ***,lots of fine‘eutectic cells’were formed in the matrix *** a result of the preferential formation of TiB2 during solidification,the amount of the eutectic borides in the steel modified with Ti was significantly ***,the continuity of the eutectic borides network was *** a word,the present work provides a promising method to modify the solidification microstructure for high borated stainless steels.

关键词： Borated stainless steels Solidification microstructure Rare earth Titanium

Behavioral evidence for the origin of Chinese Kunming dog

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Current Zoology 2021年第4期67卷 469-471页

作者： Jin-Xiu Li Qing-guo Huang Shi-Zhi wang Qi-Jun Zhou Xu Gao Ya-Ping Zhang guo-dong wang State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunming650223China Kunming Police Dog Base of the Chinese Ministry of Public Security Kunming650204China Harbin Police Dog Training Centre Heilongjiang General Station of Exit and Entry Frontier InspectionHarbin150000China Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunming650223China

As the only working dog independently developed and bred in China,Chinese Kunming dog(CKD)was approved as a new breed by the Chinese National Livestock and Poultry Genetics Commission in *** CKD is widely used by the Chinese army and police and has been exported to Singapore,Thailand,Vietnam,North Korea,and other more than 10 countries as working *** published studies of CKD have focused on coat color genetics(wang et al.2013)and reproduction performance(Wei et al.2018).The study by wang et al.(2013)pointed out that the breed of CKD was developed in the 1950s by hybridizing German shepherd dogs(GSDs)imported from the Soviet Union with Kunming indigenous village dogs.

关键词： behavior test Chinese Kunming dog origin

Upgrade Rolling Based on Ultra Fast Cooling Technology for C-Mn Steel

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Journal of Iron and Steel Research International 2014年第1期21卷 86-90页

作者： Xiao-guang ZHOU Zhen-yu LIU Sheng-yong SONG Di WU guo-dong wang State Key Laboratory of Rolling and Automation Northeastern University

By measuring the expansion curves of a C-Mn steel at different cooling rates by using an MMS-300 thermo- mechanical simulator, continuous cooling transformation curves were obtained. The new process ＂ultra fast cooling＋ laminar cooling＂ was simulated and the effects of ultra fast cooling ending temperature on microstructure had also been investigated. The hot rolling experiment was done by adopting ＂high temperature rolling-[-forepart ultra fast cooling＂ technologies at laboratory scale. The results revealed that ultra fast cooling can delay the decrease of disloca- tion density and refine ferrite grains. Diversity control of the microstructure and phase transformation strengthening can be realized by changing the ultra fast cooling ending temperature. With the decrease of ultra fast cooling ending temperature, the strength and toughness increase, but plasticity does not decrease obviously. The new technique can improve the yield strength by over 50 MPa. Therefore, the upgrade of mechanical properties of C-Mn steel can be realized by using ＂high temperature rolling＋ ultra fast cooling＋laminar cooling＂ technique. Compared with ＂low temperature rolling with large deformation degree＂ technique, this new technology can decrease the roiling force and in- crease the production efficiency.

关键词： ultra fast cooling C-Mn steel grain refinement strengthening phase transformation strengthening grain size

Characteristics and stability of oxide+carbonitride in H13 steel at 1250℃

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Journal of Iron and Steel Research International 2024年第1期31卷 134-142页

作者： Xiao-lin Sun Han-jie guo Jing guo Fei wang dong Xu Gao-yang Song Shuai wang School of Materials Science and Engineering Hebei University of EngineeringHandan056038HebeiChina School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China High Temperature Materials Research Institute Central Iron and Steel Research Institute Co.Ltd.Beijing100081China Technology Innovation Center for High Quality Cold Heading Steel of Hebei Province Hebei University of EngineeringHandan056038HebeiChina

The morphology,size,quantity,and composition of complex oxide+carbonitride in H13 steel held at 1250℃for 5,10,and 15 h were *** results show that the ratio and number of complex carbonitrides with cores in H13 steel are gradually increased when holding at 1250℃compared with those in the original H13 steel,and the core size *** are one or more oxide cores in(Ti_(x),V_(1-x))(Cy,N_(1-y)),including xCaO·zAl_(2)O_(3),xCaO·yMgO·zAl_(2)O_(3),and CaO after holding at 1250℃,in addition to MgO·Al_(2)O_(3)and Al_(2)O_(3)in the original *** equilibrium temperature for(Ti_(x),V_(1-x))(Cy,N_(1-y))precipitation at the solidification front and decomposition in the solid state was theoretically analyzed,which was affected by the x value and the product of Ti and N contents in H13 ***,the composition of(Ti_(x),V_(1-x))(Cy,N_(1-y))is influenced by the oxide *** is convinced that(Ti_(x),V_(1-x))(Cy,N_(1-y))with oxide cores has a higher stability,especially for oxides with a high Al_(2)O_(3)*** treatment at high temperature facilitates a more reasonable analysis of oxide+carbonitride,and the generation mechanism of oxide+carbonitride was discussed.

关键词： Complex carbonitride Decomposition Oxide core Characteristic Stability