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数学学报（中文版） 2014年第1期57卷 131-138页

作者：杨国英成军祥河南理工大学数学系焦作454000

在这篇文章中,我们讨论了带有非线性边界条件和权函数的的拟线性方程组,主要借助对Nehari流形的分析,在合适的参数条件下得到了方程组至少有两个不同的非平凡正解.

关键词：方程组正解非线性边界条件

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第1期68卷 288-296页

作者： Shuai Liu Wen-Qiang Xu ying-Tong Di Man-Cheng Tang Ding-Kang Chen Ming-Ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan Jun-Bo yang Zhi-Li Zuo Han guo Zi-Fei Xu ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

关键词： metabolon Diels-Alder reaction semipinacol rearrangement biosynthesis notoamides spiro polycyclic alkaloids

High Efficiency Pb-In Binary Metal Perovskite Solar Cells

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High Efficiency Pb-In Binary Metal Perovskite Solar Cells

第三届新型太阳能电池学术研讨会

作者： Meng Li Zhao-Kui Wang ying-guo yang Xing-Yu Gao Liang-Sheng Liao Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Institute of Functional Nano & Soft Materials (FUNSOM)Soochow University Shanghai Synchrotron Radiation Facility Shanghai Institute of Applied PhysicsChinese Academy of Sciences

Organometal halide perovskite solar cells bring a very competitive and fascinating prospect on solution-processable photovoltaic devices by their unimaginable efficiency ***,the fain utilization of lead in the materials will cause inevitable toxicology issue to the *** new non-toxic materials to substitute lead is an important and urgent *** we propose and investigate an alternative organic-inorganic perovskite,CHNHPbInaI Cla,where part of lead(II) is substituted by Indium(III).Grazing incidence X-ray diffraction reveals that the perovskite films exhibit multiple ordered crystal orientations,which lead to substantially improved power conversion efficiency of 17.55% in a planar heterojunction device compared with 12.61% in a pure-lead based control *** work demonstrates the possibility to substitute lead(II) in organometal halide perovskites by Indium(III) besides Tin(II).The finding promotes the lead substitution to explore new alloy perovskite systems and paves one way to tune the crystallization kinetics of organometal halide perovskites for enhanced photovoltaic devices.

关键词： Multiple ordered crystal orientations Pb and In chlorides Perovskite solar cells

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郑州市道路绿化分析、评价及模式构建

中国园林 2017年第5期33卷 80-85页

作者：王献郭英田朝阳河南农业大学林学院郑州大学综合设计院有限公司

采用定量化的方法,对郑州市常用的56种行道树的树冠体量进行调查和量化排序,并按冠幅分为6类;对郑州市40条不同类型的典型道路绿化状况进行调查、分析及评价,结果表明:调查范围内道路的平均绿地率为10.16%,平均覆盖率69.72%,主要行道树... 详细信息

采用定量化的方法,对郑州市常用的56种行道树的树冠体量进行调查和量化排序,并按冠幅分为6类;对郑州市40条不同类型的典型道路绿化状况进行调查、分析及评价,结果表明:调查范围内道路的平均绿地率为10.16%,平均覆盖率69.72%,主要行道树的平均覆盖率64.83%。影响道路绿化效果的主要原因是较宽路段或新建路段种植小冠幅树种、低龄树种或高干嫁接树种,导致现阶段的行道树冠幅太小,无法满足遮阴需求。提出了"适路适树""多板多带"等应对措施。结合乔木体量量化研究结果,构建了郑州市道路绿化的配置模式。

关键词：园林植物树冠体量定量化道路绿化覆盖率郑州市

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政府治理机制对我国区域经济收敛性的影响

山东大学学报（哲学社会科学版） 2017年第4期 8-18页

作者：郭英彤杨成荣曹佳吉林大学商学院吉林大学

中国区域经济增长的收敛问题一直备受学术界关注,现有研究结果存在很大的分歧:从不存在收敛到俱乐部收敛到有条件收敛。产生分歧的根本原因是忽视了政府治理机制对于各地经济增长水平的影响。从中国"经济分权政治集中"的政府治理机制出... 详细信息

中国区域经济增长的收敛问题一直备受学术界关注,现有研究结果存在很大的分歧:从不存在收敛到俱乐部收敛到有条件收敛。产生分歧的根本原因是忽视了政府治理机制对于各地经济增长水平的影响。从中国"经济分权政治集中"的政府治理机制出发,会产生促进区域经济收敛到相近水平的可能性。以财政分权代表经济分权,官员升迁制度代表政治集中,结合2002 2013年的数据,分两阶段对该治理机制与区域经济收敛的关系进行深入探讨。实证分析结果表明:纳入政府行政体制因素和空间相关性,我国区域经济增长即是条件收敛的。但是经济分权对该收敛过程无显著影响。

关键词：条件收敛财政分权制度官员升迁制度

Unveiling phosphofructokinase as the key target: an innovative strategy combining pull-down assays with optical imaging for snail-killing mechanism exploration

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Science China Chemistry 2025年

作者： Yuxun Lu Weisi Wang Le Yu Yuqiang Zhao ying Chen Yunhai guo Bingrong Luo Yuhua Liu Shizhu Li Liping Duan ying Zhou Yunnan Characteristic Plant Extraction Laboratory College of Chemical Science and Technology Yunnan University College of Biological and Chemical Engineering Guangxi University of Science and Technology National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector Biology WHO Collaborating Centre for Tropical Diseases National Center for International Research on Tropical Diseases School of Chemistry and Environment Yunnan Minzu University Dali Institute of Schistosomiasis Control

The Pomacea canaliculata, also known as apple snail, is an invasive species in China, posing a serious threat to agricultural production and public health. To prevent its rampant infestation, we developed a highly efficient snail-killing lead compound, 1-(4-chlorophenyl)-3-(pyridin-3-yl)urea (PBQ). However, the killing mechanism of PBQ remains unclear. To elucidate this, two novel compounds, B-PBQ and J-PBQ, were developed through structural modification of PBQ and were used, through both protein pull-down assay and confocal laser scanning microscopy imaging, to identify and confirm that phosphofructokinase(PFK) in the apple snail is the primary target protein of PBQ. Further studies revealed that PBQ successfully inhibits the activity,content, and expression of PFK in apple snail, disrupting the glycolysis pathway and leading to abnormal energy *** disruptions impair the snail’s tolerance to low oxygen, resulting in its efficient eradication. These findings offer a promising direction for developing next-generation PFK-targeted snail-killing pesticides. Furthermore, the strategy of combining pull-down assays with optical imaging used in this work provides a novel approach for the exploration of mechanisms of other pesticide candidates.

关键词：

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基于计算智能的模糊规则自动生成

上海交通大学学报 1999年第11期33卷 1409-1413页

作者：杨杰郭英凯杨勇上海交通大学图像处理和模式识别研究所上海200030

介绍模糊控制开发系统中隶属函数编辑、模糊规则生成与优化、目标代码生成的原理和功能，提出了基于多层感知器网络、五层模糊神经网、遗传算法的模糊规则自动生成算法。

关键词：模糊控制遗传算法模糊规则自动生成智能控制

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烟叶收购等级合格率的提高途径探析

现代农业科技 2017年第15期 291-293页

作者：施国涛杨应伟云南省烟草公司普洱市公司景谷县分公司云南景谷665000

烟叶收购是烟叶生产工作中的重要环节,烟叶等级合格率和等级纯度是衡量烟叶等级质量的一项重要指标。本文分析了在烟叶收购等级质量中存在的问题及原因,提出了提高烟叶收购等级合格率的改进措施和管控方法。

关键词：烟叶收购等级合格率提高途径

Dissection of additive, epistatic effect and Qx E interation of quantitative loci influencing grain yield, biomass and harvest index in rice

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Dissection of additive, epistatic effect and Qx E interation...

基于SCoT标记的陕产茜草野生居群遗传多样性分析

湖北省遗传学会、江西省遗传学会2006年学术年会暨学术讨论会

作者： guo-Hua yang, Bing Yue, Yong-Zhong Xing, yang Wang, Jing-Zheng Ding, Ji-Ping Tong, ying-guo Zhu, yang-Sheng Li Key Laboratory of the Education Ministry of China for Plant Developmental Biology, College of Life Sciences, Wuhan University, Wuhan 430072, P. R. China National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430072, P. R. China

The dramatic increasing in rice yield is largely attributable to improvement in total biomass and harvest index. In this study, we analyzed the main effect, epistatic effect of QTLs, and QTL by environment interactions of harvest index (HI), biomass (BM) and grain yield (GY), using a population of 241 recombinant inbred lines derived from a cross between Zhenshan 97 and Minghui 63. The data were collected from the field experiments conducted in two succeeding years, and QTL analysis was performed using QTL mapper 1.6. A total of 11 main-effect QTLs and 23 epistatic interactions involving 34 loci were detected for the three traits, and collectively explained 16.02-16.64% and 26.33-32.91% of phenotypic variation, respectively. No significant QTLs by environment interactions were detected in the two years. This indicated the epistatic effects were more pronounced than the main effects for these traits. One main-effect QTLs and one pair of epistatic interaction influenced GY and BM simultaneously in the same direction, and 5 loci involved in the epistatic interactions were associated with GY and HI or GY and BM at the same time. No QTL for HI was overlapped with the region for BM. The correlation and regression analysis also showed that both BM and HI contributed to increasing GY, however, negative correlation existed between BM and HI. These results suggest that the importance of epistasis and the compromise of BM and HI are the key problems for high yield breeding in rice.

关键词： Oryza sativa L., biomass, harvest index, grain yield, genetic basis

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药学学报 2017年第10期52卷 1621-1628页

作者：彭亮黄涛张岗胡本祥王媛媛任瀛郭琦杨冰月陕西中医药大学药学院陕西西安712046 陕西省中药资源产业化协同创新中心陕西西安712046

茜草是我国传统中药材,近年来,其药材价格不断上涨,导致野生资源急剧减少,因此对其野生资源的遗传多样性进行评价,对茜草的资源保护、优良品种选育和开发利用意义重大。本文采用SCoT分子标记方法对陕西境内8个野生茜草居群64份种质进行... 详细信息

茜草是我国传统中药材,近年来,其药材价格不断上涨,导致野生资源急剧减少,因此对其野生资源的遗传多样性进行评价,对茜草的资源保护、优良品种选育和开发利用意义重大。本文采用SCoT分子标记方法对陕西境内8个野生茜草居群64份种质进行了遗传多样性和遗传结构分析。结果表明,陕产野生茜草遗传多样性丰富,14条引物共扩增得到182条带,其中多态性条带163条,多态性百分比为89.56%;种群水平上Nei’s基因多样性指数(H)为0.293 6、Shannon指数(I)平均值为0.444 6、居群间遗传分化系数(Gst)为0.555 3、种群间基因流(Nm)为0.440 8;不同野生居群按遗传多样性水平排序为:安康>榆林>商洛>宝鸡>铜川>延安>渭南>咸阳。Mantel分析表明,陕产茜草野生居群间的亲缘关系与它们之间的地理距离存在显著的正相关性(r=0.776 4,P<0.05)。本文为陕产茜草野生居群的保护和资源利用提供了理论依据。

关键词：茜草 SCoT 种质资源遗传多样性