检索结果-南通市图书馆

A New Stilbene Tetramer from Caragana rosea

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2003年第10期14卷 1048-1050页

作者： guo xun YANG, Chang Qi HU School of Pharmacy, Fudan University, Shanghai 200032 School of Pharmacy Fudan University Shanghai 200032 China

Cararosinol A, a new stilbene tetramer, was isolated from Caragana rosea. Its structure has been established on the basis of spectroscopic evidence.

关键词： Caragana rosea Leguminase stilbene tetramer.

A new tetrastilbene from Caragana sinica

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2008年第6期19卷 711-715页

作者： Ke Jun Cheng Da You Ma guo xun Yang Chang Qi Hu Department of Chemistry of Natural Products Fudan University Shanghai 200032 China

A new tetrastilbene named carasinol D （1） was isolated from the roots of Caragana sinica. Its structure was elucidated by spectroscopic analysis. Compound 1 was obtained from carasinol B （2） by an acid-catalyzed c... 详细信息

关键词： Caragana sinica Stilbenoids Carasinol D Carasinol B

Regeneration of the heart:f rom molecular mechanisms to clinical therapeutics

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2024年第1期11卷 80-97页

作者： Qian-Yun guo Jia-Qi Yang xun-xun Feng Yu-Jie Zhou Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease Beijing Institute of Heart Lung and Blood Vessel DiseaseClinical Center for Coronary Heart DiseaseDepartment of CardiologyBeijing Anzhen HospitalCapital Medical UniversityBeijing 100029China

Heart injury such as myocardial infarction leads to cardiomyocyte loss,fibrotic tissue deposition,and scar *** changes reduce cardiac contractility,resulting in heart failure,which causes a huge public health *** personnel,compared with civilians,is exposed to more stress,a risk factor for heart diseases,making cardiovascular health management and treatment innovation an important topic for military *** far,medical intervention can slow down cardiovascular disease progression,but not yet induce heart *** the past decades,studies have focused on mechanisms underlying the regenerative capability of the heart and applicable approaches to reverse heart *** have emerged from studies in animal models and early clinical *** interventions show the potential to reduce scar formation and enhance cardiomyocyte proliferation that counteracts the pathogenesis of heart *** this review,we discuss the signaling events controlling the regeneration of heart tissue and summarize current therapeutic approaches to promote heart regeneration after injury.

关键词： Heart regeneration Cardiac disease Therapeutics Signaling mechanisms

Case report and review of the literature of primary gastrointestinal amyloidosis diagnosed with enteroscopy and endoscopic ultrasonography

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2018年第9期6卷 284-290页

作者： Yi-Pin Liu Wei-Wei Jiang guo-xun Chen Yan-Qing Li Department of Gastroenterology Qilu Hospital Shandong University Department of Gastroenterology Yantai Affiliated Hospital of Binzhou Medical University Department of Nutrition University of Tennessee

Here, we report a rare case of primary gastrointestinal amyloidosis in a stable condition after being followed up for three years. The patient was admitted to the hospital in 2014. Tests showed decreased levels of hemoglobin and ferritin. Transoral and transanal enteroscopy showed multiple nodular protuberances in the esophagus, ileum, colon and rectum. Endoscopic ultrasonography indicated the nodular protuberances stemmed from the submucosa and partially invaded the intrinsic myometrium. Pathological examinations found multiple small nodules in the submucosa and dyed structures, which were positive for special Congo red dyeing. After treatment with oral iron supplements, the levels of hemoglobin and ferritin became normal. It is concluded that the patient represents a case of primary gastrointestinal amyloidosis with multiple nodular protuberances in the digestive tract with controllable moderate abdominal discomfort and anemia and a benign course. Enteroscopy and endoscopic ultrasonography play an important role in the diagnosis of primary gastrointestinal amyloidosis.

关键词： Enteroscopy Primary gastrointestinal amyloidosis Endoscopic ultrasonography Pathological diagnosis

Development of an electronic stopping power model based on deep learning and its application in ion range prediction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2022年第7期31卷 255-261页

作者： xun guo Hao Wang Changkai Li Shijun Zhao Ke Jin Jianming Xue Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyBeijing 100081China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Department of Mechanical Engineering City University of Hong KongHong KongChina Center for Applied Physics and Technology Ministry of Education Key Laboratory of High Energy Density Physics Simulationsand Peking University Branch of Ministry of Education IFSA CenterPeking UniversityBeijing 100871China

Deep learning algorithm emerges as a new method to take the raw features from large dataset and mine their deep implicit relations,which is promising for solving traditional physical challenges.A particularly intricate and difficult challenge is the energy loss mechanism of energetic ions in solid,where accurate prediction of stopping power is a longtime *** this work,we develop a deep-learning-based stopping power model with high overall accuracy,and overcome the long-standing deficiency of the existing classical models by improving the predictive accuracy of stopping power for ultra-heavy ion with low energy,and the corresponding projected *** electronic stopping power model,based on deep learning algorithm,could be hopefully applied for the study of ion-solid interaction mechanism and enormous relevant applications.

关键词： electronic stopping power deep learning ion range reciprocity theory

Advanced natural products chemistry research in China between 2015 and 2017

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2018年第12期16卷 881-906页

作者： YANG guo-xun MA Guang-Lei LI Hao HUANG Ting XIONG Juan HU Jin-Feng Department of Natural Products Chemistry School of Pharmacy Fudan University

In this review, we intensively focus on the advances in research of natural products(NPs) discovery carried out by domestic scholars in China from 2015 through 2017. In general, a total of 1811 publications(1479 in English and 332 in Chinese) were accumulated regarding newly isolated NPs from plants, microorganisms, and marine sources. As a result, 277 selected papers concerning naturally occurring compounds with extraordinary frameworks, origins, and promising activities were discussed in this review article, mainly organized according to their structural classes and novelties.

关键词： Natural Products Chemistry Novel Structures Research Progress Review

Prediction of the maximum water inflow in Pingdingshan No.8 mine based on grey system theory

在线全文

学校读者我要写书评

暂无评论

Journal of Coal Science & Engineering(China) 2012年第1期18卷 55-59页

作者： Xu, Jie Jing, guo-xun Xu, Yao-yao School of Safety Science & Engineering Henan Polytechnic University Jiaozuo China Geological Survey Office of Pingdingshan No.8 Mine Pingdingshan China

In order to prevent and control the water inflow of mines, this paper built a new initial GM（1, 1） model to torecast the maximum water inflow according to the principle of new information. The effect of the new initial GM（1, 1） model is not ideal by the concrete example. Then according to the principle of making the sum of the squares of the difference between the calculated sequences and the original sequences, an optimized GM（1, I） model was established. The result shows that this method is a new prediction method which can predict the maximum water inflow accurately. It not only conforms to the guide- line of prevention primarily, but also provides reference standards to managers on making prevention measures.

关键词： prediction maximum water inflow grey system theory GM(1 1) model

基于国家专利的中药复方治疗糖尿病周围神经病变用药规律研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界中西医结合杂志 2024年第9期19卷 1697-1702,1707页

作者：刘江腾王乐李泽宇郭志卂张华北京中医药大学东直门医院北京100700

目的基于数据挖掘技术对国家专利数据库中治疗糖尿病周围神经病变(Diabetic peripheral neuropathy,DPN)的中药复方专利进行分析,挖掘其用药配伍及组方规律。方法检索1985年9月10日—2024年1月1日期间国家知识产权局治疗DPN的中药复方专... 详细信息

目的基于数据挖掘技术对国家专利数据库中治疗糖尿病周围神经病变(Diabetic peripheral neuropathy,DPN)的中药复方专利进行分析,挖掘其用药配伍及组方规律。方法检索1985年9月10日—2024年1月1日期间国家知识产权局治疗DPN的中药复方专利,运用古今医案云平台(V2.3.7)及SPSS Statistics 26.0统计学软件对符合纳入标准的专利复方进行药物频次和性味归经统计、关联规则分析、系统聚类分析。结果共纳入治疗DPN的中药复方专利66首,涉及中药149味。高频药物依次为黄芪、川芎、当归、丹参、桂枝、鸡血藤等;药性以温性药最多,其次为平性、微寒等,药味以甘味最多,其次为辛味、苦味等,归经主要为肝经、脾经、心经等;关联规则以益气活血类置信度最高,药物组合前三位为川芎-黄芪、丹参-黄芪、当归-黄芪,以黄芪为核心药物;聚类分析获得的药物组合有“丹参、生地黄、赤芍、延胡索、牛膝、红花、桃仁”“川芎、当归、黄芪、鸡血藤、桂枝、地龙”和“蜈蚣、甘草”等。结论中药复方治疗DPN注重气血同调,以益气活血为基本治法,根据病情配合滋阴、温阳、通络、止痛等法,常用补阳还五汤、黄芪桂枝五物汤、当归四逆汤、止痉散等方化裁,可为DPN的临床治疗及新药研发开拓思路、提供参考。

关键词：糖尿病周围神经病变专利中药复方组方规律数据挖掘

Experimental study and numerical simulation of gas/particle flow in tunneling of mine

在线全文

学校读者我要写书评

暂无评论

Journal of Coal Science & Engineering(China) 2009年第1期15卷 85-87页

作者： LU Zhong-liang LI Hai-xia guo Pei-hong JING guo-xun School of Safety Science and Engineering Henan Polytechnic University Jiaozuo 454000 China School of Mechanical and Power Engineering Henan Polytechnic University Jiaozuo 454000 China

Respiration particles can be collected into a dust catcher by an inside inhalingand outside pressing particle collector. The work environment of the grab operator in tunneling mining was improved when a dust catcher is placed before the working face of thegrab operator. The particle movement was affected by the gas flow. The flow field insideand outside the dust collector was simulated. The effect of the operating parameter wasanalyzed. The numerical results show a good approach to predict the gas flow and particledistribution in the inside and outside of the particle collector.

关键词： grab working face particle movement inside inhaling and outside pressing particle collector