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油菜素内酯调控植物耐盐机理研究进展

中国农业科技导报 2024年第2期26卷 1-12页

作者：陈晨程大伟李兰顾红郭西智李明陈锦永中国农业科学院郑州果树研究所果树生长发育与品质控制重点开放实验室郑州450009

油菜素内酯(brassinosteroid,BR)作为新型、高效的植物激素,广泛参与植物的各种生理过程,可以缓解多种非生物胁迫。阐述了BR处理缓解盐胁迫的生物学功能,总结了拟南芥、农作物水稻以及多种园艺植物的BR信号通路,并通过介绍BR的耐盐机理... 详细信息

油菜素内酯(brassinosteroid,BR)作为新型、高效的植物激素,广泛参与植物的各种生理过程,可以缓解多种非生物胁迫。阐述了BR处理缓解盐胁迫的生物学功能,总结了拟南芥、农作物水稻以及多种园艺植物的BR信号通路,并通过介绍BR的耐盐机理,进一步分析了植物遭受盐胁迫时的应答信号转导通路,旨在为加强BR在提高植物耐盐方面的应用提供理论依据。

关键词：油菜素内酯植物激素耐盐作用机理

维普期刊数据库博看期刊

Analysis of coseismic effect on temperature in the Three Gorges well network

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Geodesy and Geodynamics 2015年第1期6卷 61-66页

作者： Zhang Weihua Wang Qiuliang Li Jinggang Luo Junqiu guo xizhi Key Laboratory of Earthquake Geodesy Institute of Seismology China Earthquake Administration Wuhan Base of Institute of Crustal Dynamics China Earthquake Administration Key Seismic Monitoring Station of the Three Gorges Project Ecological and Environmental Monitoring System

Through the Three Gorges well network, we examine different coseismic changes in water temperature caused by local earthquakes since 2008, and offer a mechanistic *** relations between the coseismic changes in water t... 详细信息

关键词： Three Gorges well network Coseismic effect Local earthquake Well water temperature Magnitude Epicenter distance Focal mechanism

β-catenin activation in hair follicle dermal stem cells in duces ectopic hair outgrowth and skin fibrosis

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Journal of Molecular Cell Biology 2019年第1期11卷 26-38页

作者： Yixin Tao Qingchun Yang Lei Wang Jie Zhang Xuming Zhu Qianqian Sun Yunbin Han Qian Luo Yushu Wang xizhi guo Ji Wu Baojie Li Xiao Yang Lin He Gang Ma Bio-X-Renji Hospital Research Center Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200240China Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders(Ministry of Education) Bio-X InstitutesShanghai Jiao Tong UniversityShanghai 200240China School of Life Science and Biotechnology Shanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Proteomics Genetic Laboratory of Development and DiseasesInstitute of BiotechnologyBeijing 100071China

Hair follicle dermal sheath(DS)harbors hair follicle dermal stem cells(hfDSCs),which can be recruited to replenish DS and dermal papilla(DP).Cultured DS cells can differentiate into various cell lineages in ***,it is unclear how its plasticity is modulated in ***/β-catenin signaling plays an important role in maintaining stem cells of various lineages and is required for HF development and *** we report that activation ofβ-catenin in DS generates ectopic HF outgrowth(EF)by reprogramming HF epidermal cells and DS cells themselves,and endows DS cells with hair inducing *** homeostasis of pre-existing HFs is ***,cell-autonomous progressive skin fibrosis is prominent in dermis,where the excessive fibroblasts largely originate from *** expression analysis of purified DS cells with activatedβ-catenin revealed significantly increased expression of Bmp,Fgf,and Notch ligands and administration of Bmp,Fgf,or Notch signaling inhibitor attenuates EF *** summary,our findings advance the current knowledge of high plasticity of DS cells and provide an insight into understanding how Wnt/β-catenin signaling controls DS cell behaviors.

关键词： Wnt/β-catenin fibrosis hair follicle skin cell differentiation

Co-seismic groundwater-level and temperature changes of the 2011 Mw9. 0 Japan earthquake in Chinese mainland

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Geodesy and Geodynamics 2011年第4期2卷 40-45页

作者： Luo Junqiu Sun Linli Zhang Weihua Li Ming guo xizhi Eaarthquake Administration of Hubei Province Wuhan 430071China

Co-seismic groundwater-level and temperature changes caused by the Mw9. 0 Japan earthquake in Chinese mainland are described. The recorded water-level changes were mostly oscillations, with some step decreases mostly in the coastal area of Southeast China and step increases mostly in Northeast China and the North-South Seismic Belt. The water-temperature changes were mainly decrease with slow recovery in Sichuan- Yunnan, South China, and lower reaches of Jiangzhong, and sharp increase followed by sharp decrease, or vice versa, in North China and Northeast China. For wells that showed step changes in both water level and temperature, more showed them in the same direction than in the opposite direction.

关键词： Japan Mw9.0 earthquake co-seismic change groudwater level groundwater temperature

Characterization of a novel missense mutation on murine Pax3 through ENU mutagenesis

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Journal of Genetics and Genomics 2011年第8期38卷 333-339页

作者： Yue Xiao Lingling Zhang Kuanjun He Xiang Gao Lun Yang Lin He Gang Ma xizhi guo Bio-X Center Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders Shanghai Jiao Tong University Shanghai 200240 China Medical School of Nanjing University Model Animal Research Center Nanjing 210093 China These authors contr-ibuted equally to this paper.

N-ethyl-N-nitrosourea （ENU） mutagenesis has led to the elucidation of several regulator genes for melanocyte and skin development. Here we characterized a mutant from ENU mutagenesis with similar phenotype as that of Splotch mutant, including exencephaly, spina bifida and abnormal limbs in homozygotes as well as white belly spotting and occasionally loop-tail in heterozygotes. This novel mutant was named as SpxG. Through genome-wide linkage analysis in backcross progenies with microsatellite markers, the SpxG was confined to a region between DIMIT415 and DIMIT7 on chromosome 1, where notable Pax3 gene was located. Direct sequencing revealed that SpxG carried a nucleotide A894G missense transition in exon 6 of Pax3 gene that resulted in Asn to Asp substitution at amino acid 269 within the highly-conserved homeodomain （HD） DNA recognition module, which was the first point mutation found in this domain in mice. This N269D mutation impaired the transactivation capacity of Pax3 protein, but exerted no effect on Pax3 protein translation. The characterization of the new mutation expanded our understanding the transactivation and DNA-binding structure of Pax3 protein.

关键词： White spotting Neural tube defect ENU Pax3 Transactivation

Wnt信号通路调控脂肪发育与代谢的研究进展

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中国科学：生命科学 2017年第4期47卷 355-362页

作者：曹怡玮郭熙志上海交通大学Bio-X研究院遗传发育与精神疾病教育部重点实验室上海200240

肥胖是形成Ⅱ型糖尿病和心血管疾病的重要风险因子.Wnt信号通路是调控多个细胞发育与分化的重要信号因子.本研究介绍了脂肪组织结构、脂肪细胞分化的调控因子、经典和非经典Wnt信号通路.从肥胖与糖尿病的临床观察、脂肪分化与发育、线... 详细信息

肥胖是形成Ⅱ型糖尿病和心血管疾病的重要风险因子.Wnt信号通路是调控多个细胞发育与分化的重要信号因子.本研究介绍了脂肪组织结构、脂肪细胞分化的调控因子、经典和非经典Wnt信号通路.从肥胖与糖尿病的临床观察、脂肪分化与发育、线粒体代谢与炎症反应的角度,阐述了经典和非经典Wnt信号通路对脂肪发育和代谢的影响.

关键词： Wnt信号通路脂肪细胞分化 Ⅱ型糖尿病

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我拍《工厂青年》

青年学报 2019年第1期 22-27页

作者：郭熙志深圳大学传媒与文化发展研究中心

纪录片的社会议题与电影形式有其复杂的诞生过程。纪录片《工厂青年》选择了"不干预"的态度进入了形式与内容的探索。导演的三十年文学修养与纪录片电影实践的结合,在一个否定之否定过程中,形成了现代主义美学与现实主义现实互动,在当... 详细信息

纪录片的社会议题与电影形式有其复杂的诞生过程。纪录片《工厂青年》选择了"不干预"的态度进入了形式与内容的探索。导演的三十年文学修养与纪录片电影实践的结合,在一个否定之否定过程中,形成了现代主义美学与现实主义现实互动,在当代纪录片中独树一帜。

关键词：纪录片现代主义不干预美学

回到生命:岁月、生活和人——纪录片《渡口编年·贺家》的拍摄

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戏剧与影视评论 2019年第4期 91-99页

作者：郭熙志深圳大学

一、百年渡口停渡《渡口编年》,顾名思义,渡口就是我老家的渡口。1998年股份制改制,渡口轮船公司要求职工下岗,要改革成私人性质的承包单位。自1998年开始,我跟踪拍摄轮船公司的三个工人家庭二十年,其中,周家、陶家都是下岗职工,贺家交... 详细信息

一、百年渡口停渡《渡口编年》,顾名思义,渡口就是我老家的渡口。1998年股份制改制,渡口轮船公司要求职工下岗,要改革成私人性质的承包单位。自1998年开始,我跟踪拍摄轮船公司的三个工人家庭二十年,其中,周家、陶家都是下岗职工,贺家交不起承包费从渡口撤出来了。拍摄了二十年,故取名《渡口编年》。

关键词：《渡口编年·贺家》维尔托夫

Mesenchymal TGF-β signaling orchestrates dental epithelial stem cell homeostasis through Wnt signaling

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Mesenchymal TGF-β signaling orchestrates dental epithelial ...