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Feasible management of median arcuate ligament syndrome in orthotopic liver transplantation recipients

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World Journal of Gastrointestinal Surgery 2022年第9期14卷 976-985页

作者： Shu-Xuan Li Ye-Hui Fan Guang-Yao Tian guo-Yue lv Department of Hepatobiliary and Pancreatic Surgery The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of The First Operation Room The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

BACKGROUND In orthotopic liver transplantation(OLT)recipients,median arcuate ligament syndrome(MALS)is considered a risk factor for hepatic arterial thrombosis(HAT),which is dreadful for OLT *** alternative surgical procedures have been proposed to overcome the impact of MALS on transplantation,but clinical evidence is still *** To evaluate the feasible surgical management of MALS to reduce complications in OLT *** Data for 288 consecutive patients who underwent OLT at The First Hospital of Jilin University between January 2017 and July 2020 were retrospectively *** surgical management of median arcuate ligament(MAL)and modifications to the arterial anastomosis were *** perioperative and long-term prognosis of MALS recipients were *** preoperative and postoperative data of patients were analyzed in a descriptive *** Eight patients with MALS were included in this *** first patient with MALS received no intervention during the primary surgery and developed postoperative *** liver transplantation with MAL division was successfully *** artery(GDA)preservation with splenic artery ligation was performed on three patients,only GDA preservation was performed on two patients,and no intervention was performed on two *** patient developed HAT after surgery and postoperative recovery was *** The preservation of collateral circulation between the superior mesenteric artery and celiac trunk via the GDA with or without splenic artery ligation is a safe and feasible alternative to MAL division.

关键词： Orthotopic liver transplantation Median arcuate ligament syndrome Surgical complications Surgical management Hepatic artery thrombosis

Efficacy of telbivudine in HBeAg-positive chronic hepatitis B patients with high baseline ALT levels

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World Journal of Gastroenterology 2010年第32期16卷 4095-4099页

作者： guo-Cai lv Wen-Jiang Ma Lin-Jung Ying Xi Jin Lin Zheng Yi-Da Yang State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Department of Infectious Diseases First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 Zhejiang ProvinceChina

AIM:To evaluate the efficacy and safety of telbivudine(LDT) in hepatitis B e antigen(HBeAg)-positive chronic hepatitis B(CHB) patients who have high baseline alanine aminotransferase(ALT) levels between 10 and 20 times the upper limit of ***:Forty HBeAg-positive CHB patients with high baseline ALT levels between 10 and 20 times the upper limit of normal were enrolled and received LDT monotherapy for 52 *** forty patients with baseline ALT levels between 2 and 10 times the upper limit of normal were included as *** compared the virological,biochemical,serological and side effect profiles between the two groups at 52 ***:By week 52,the mean decrease in hepatitis B virus(HBV) DNA level compared with baseline was 7.03 log10 copies/mL in the high baseline ALT group and 6.17 log10 copies/mL in the control group,respectively(P < 0.05).The proportion of patients in whom serum HBV DNA levels were undetectable by polymerase chain reaction assay was 72.5% in the high baseline ALT group and 60% in the control group,respectively(P < 0.05).In addition,45.0% of patients in the high baseline ALT group and 27.5% of controls became HBeAg-negative,and 37.5% of those in the high baseline group and 22.5% of controls,respectively,had HBeAg seroconversion(P < 0.05) at week ***,in the high baseline group,4 out of 40 patients(10%) became hepatitis B surface antigen(HBsAg)-negative and 3(7.5%) of them seroconverted(became HBsAg-positive).Only 1 patient in the control group became HBsAg-negative,but had no *** ALT normalization rate,viral breakthrough,genotypic resistance to LDT,and elevations in creatine kinase levels were similar in the two groups over the 52 ***:High baseline ALT level is a strong predictor for optimal results during LDT treatment.

关键词： Chronic hepatitis B Hepatitis B e antigen Serum alanine aminotransferase level Telbivudine

Mechanism of fluidized chlorination reaction of Kenya natural rutile ore

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Rare Metals 2014年第4期33卷 485-492页

作者： Li-Ping Niu Pei-Yuan Ni Ting-An Zhang guo-Zhi lv Ai-Ping Zhou Xi-bin Liang De-long Meng School of Materials and Metallurgy Key Laboratory for Ecological Utilization of Multimetallic Mineral (Ministry of Education)Northeastern University Department of Material Science and Engineering KTH-Royal Institute of TechnologySE-100 44 StockholmSweden Titanium Plant Jinchuan Group Company Limited

In this paper, the thermodynamics and kinetics of nature rutile carbochlorination in a fluidized-bed were investigated. The thermodynamic calculations of TiO2-C- C12 system show that when C is excess in the solid phase, titanium tetrachloride and carbon monoxide can exist sta- bly. At high temperature, the reaction with CO as the product is the dominant reaction. The appropriate reaction conditions are as follows： reaction temperature of 950 ℃, reaction time of 40 min, carbon ratio of 30 wt% of rutile, natural rutile particle size of -96 μm, petroleum coke size of -150 μm, and chlorine flow of 0.036 m3.h-1. Under the above conditions, the reaction conversion rate of TiO2 can reach about 95 %. This paper proposed a reaction rate model, and got a rutile chlorination rate formula, which is generally consistent with the experimental data. For the TiO2-C-C12 system, the reaction rate is dependent on the initial radius of rutile particle, density, and the partial pressures of C12. From 900 to 1,000 ℃, the apparent activation energy is 10.569 ***1-1, and the mass diffu- sion is found to be the main reaction-controlling step. The expression for the chlorine reaction rate in the C-C12 sys- tem is obtained, and it depends on the degree of reaction, the partial pressure of C12, and the size of rutile particle.

关键词： Natural rutile Gas-solid reaction Fluidized-bed Carbochlorination Particle

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电力工程施工项目管理及成本控制重点探寻

电站系统工程 2024年第4期40卷 83-84页

作者：贾剑锋王辰吕国芳吴楠魏经明中国机械设备工程股份有限公司哈尔滨电站设备成套设计研究所有限公司

电力施工项目管理及成本控制是电力行业的重要组成部分,对于提高项目的管理水平和经济效益至关重要。电力施工项目管理及成本控制是电力行业中非常重要的一项工作。因此对电力工程管理模式的创新与成本控制,展开相关分析。

关键词：电力施工项目管理成本控制措施方法

Heavy element contributions of rotating massive stars to interstellar medium

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Research in Astronomy and Astrophysics 2021年第5期21卷 287-295页

作者： Rui-Qing Wu Chun-Hua Zhu guo-Liang lv Zhao-Jun Wang He-Lei Liu School of Physical Science and Technology Xinjiang UniversityUrumqi 830046China

Employing the stellar evolution code Modules for Experiments in Stellar Astrophysics(MESA),we calculate yields of heavy elements from massive stars via stellar wind and core−collapse supernova(CCSN)ejecta to the interstellar medium(ISM).In our models,the initial masses(Mini)of massive stars are taken from 13 to 80 M⊙,their initial rotational velocities(V)are 0,300 and 500 km s^(−1),and their metallicities are[Fe/H]=−3,−2,−1 and *** yields of heavy elements coming from stellar winds are mainly affected by stellar rotation which changes the chemical abundances of stellar surfaces via chemically homogeneous evolution,and enhances mass-loss *** estimate that the stellar wind can produce heavy element yields of about 10^(−2)(for low metallicity models)to a mass of severalM⊙(for low metallicity and rapid rotation models).The yields of heavy elements produced by CCSN ejecta also depend on the large amount of remnantmass which is mainly determined by the mass of the *** models calculate that the yields of heavy elements produced by CCSN ejecta can get up to several M⊙.Compared with stellar wind,CCSN ejecta has a greater contribution to the heavy elements in *** also compare the 56Ni yields calculated in this work with the observational *** models only explain the 56Ni masses produced by faint SNe or normal SNe with progenitor mass lower than about 25 M⊙,and greatly underestimate the 56Ni masses produced by stars with masses higher than about 30M⊙.

关键词： Stars:massive rotation ISM:abundances

Deactivation of Enterococcus Faecalis Bacteria by an Atmospheric Cold Plasma Brush

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Chinese Physics Letters 2012年第7期29卷 187-189页

作者： CHEN Wei HUANG Jun DU Ning LIU Xiao-Di lv guo-Hua WANG Xing-Quan ZHANG guo-Ping guo Li-Hong YANG Si-Ze Key Laboratory of Soft Matter Physics Beijing National Laboratory for Condensed Matter PhysicsInstitute of PhysicsChinese Academy of SciencesBeijing 100190 Department of Oral Biology Peking University School and Hospital of StomatologyBeijing 100080 Fujian Key Laboratory for Plasma and Magnetic Resonance Department of AeronauticsSchool of Physics and Mechanical&Electrical EngineeringXiamen UniversityXiamen 361005

An atmospheric cold plasma brush suitable for large area and low-temperature plasma-based sterilization is designed and used to treat enterococcus faecalis *** results show that the efficiency of the inactivation process by helium plasma is dependent on applied power and exposure *** plasma treatments,the cell structure and morphology changes can be observed by scanning electron *** emission measurements indicate that reactive species such as O and OH play a significant role in the sterilization process.

关键词： process Bacteria Plasma

Predicting lymph node metastasis in colorectal cancer:An analysis of influencing factors to develop a risk model

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World Journal of Gastrointestinal Surgery 2023年第10期15卷 2234-2246页

作者： Yun-Peng Lei Qing-Zhi Song Shuang Liu Ji-Yan Xie guo-Qing lv Department of Gastrointestinal Surgery Peking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina Department of Gastrointestinal Surgery Shenzhen Peking University-The Hong Kong University of Science and Technology Medical CenterPeking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina

BACKGROUND Colorectal cancer(CRC)is a significant global health issue,and lymph node metastasis(LNM)is a crucial prognostic *** prediction of LNM is essential for developing individualized treatment strategies for patients with ***,the prediction of LNM is challenging and depends on various factors such as tumor histology,clinicopathological features,and molecular *** most reliable method to detect LNM is the histopathological examination of surgically resected specimens;however,this method is invasive,time-consuming,and subject to sampling errors and interobserver *** To analyze influencing factors and develop and validate a risk prediction model for LNM in CRC based on a large patient *** This study retrospectively analyzed 300 patients who underwent CRC surgery at two Peking University Shenzhen hospitals between January and December 2021.A deep learning approach was used to extract features potentially associated with LNM from primary tumor histological images while a logistic regression model was employed to predict LNM in CRC using machine-learning-derived features and clinicopathological variables as *** The prediction model constructed for LNM in CRC was based on a logistic regression framework that incorporated machine learning-extracted features and clinicopathological *** model achieved high accuracy(0.86),sensitivity(0.81),specificity(0.87),positive predictive value(0.66),negative predictive value(0.94),area under the curve for the receiver operating characteristic(0.91),and a low Brier score(0.10).The model showed good agreement between the observed and predicted probabilities of LNM across a range of risk thresholds,indicating good calibration and clinical *** The present study successfully developed and validated a potent and effective risk-prediction model for LNM in patients with *** model utilizes machine-learning-derived features extracted from pr

关键词： Colorectal cancer Lymph node metastasis Machine learning Risk prediction model Clinicopathological factors Individualized treatment strategies

Hepatic epithelioid hemangioendothelioma:Update on diagnosis and therapy

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World Journal of Clinical Cases 2020年第18期8卷 3978-3987页

作者： Kai Kou Yu-guo Chen Jian-Peng Zhou Xiao-Dong Sun Da-Wei Sun Shu-Xuan Li guo-Yue lv Department of Hepatobiliary and Pancreatic Surgery The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

With an estimated incidence of only 1-2 cases in every 1 million people,hepatic epithelioid hemangioendothelioma(HEHE)is a rare vascular endothelial cell tumor occurring in the liver and consisting of epithelioid and histiocyte-like vascular endothelial cells in mucus or a fibrotic *** is characterized as a low-to-moderate grade malignant tumor and is classified into three types:solitary,multiple,and *** the etiology and characteristic clinical manifestations of HEHE are ***,HEHE has a characteristic appearance on imaging including ultrasound,magnetic resonance imaging,and positron emission tomography/computerized ***,its diagnosis depends mainly on pathological findings,with immunohistochemical detection of endothelial markers cluster of differentiation 31(CD31),CD34,CD10,vimentin,and factor VIII antigen as the basis of *** and/or liver transplantation are the first choice for treatment,but various chemotherapeutic drugs are reportedly effective,providing a promising treatment *** this review,we summarize the literature related to the diagnosis and treatment of HEHE,which provides future perspectives for the clinical management of HEHE.

关键词： Hepatic epithelioid hemangioendothelioma Diagnosis Differential diagnosis Therapy Prognosis Imaging

Design,synthesis and antifungal activities in vitro of novel tetralin compounds

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Chinese Chemical Letters 2008年第3期19卷 264-268页

作者： Hui Tang You Jun Zhou Yao Wu Li Jia guo lv Can Hui Zheng Jun Chen Ju Zhu Department of Medicinal Chemistry School of Pharmacy Second Military Medical University Shanghai 200433 China

Novel chiral tetralin compounds were designed and synthesized, and their antifungal activities in vitro were tested. The results showed that all of target compounds had potent antifungal activities, and were stronger than that of control compounds tetrahydroisoquinolines. The binding model of lead molecules in the active site of CYP51 of Candida albicans showed that lead compound specifically interacted with the amino acids residues in the active site, without binding with the heme of CYP51, which was different from azole antifungal drugs. The present study might afford a novel lead molecule to develop non-azole CYP51 inhihitars of fungi.

关键词： Antifungal Chiral tetralins Lanosterol 14α-demethylase Design Synthesis