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Genomics, Proteomics & Bioinformatics 2024年第2期22卷 43-56页

作者： chao Li Bingchun Chen Suo Langda Peng Pu xiaojia Zhu Shiwei Zhou Peter Kalds Ke Zhang Meenu Bhati Alexander Leonard Shuhong huang Ran Li Awang Cuoji xiran Wang Haolin Zhu Yujiang Wu Renqin Cuomu Ba Gui Ming Li Yutao Wang Yan Li Wenwen Fang ting Jia Tianchun Pu xiangyu Pan Yudong Cai Chong He Liming Wang Yu Jiang Jian-lin Han Yulin Chen Ping Zhou Hubert Pausch xiaolong Wang International Joint Agriculture Research Center for Animal Bio-Breeding Ministry of Agriculture and Rural Affairs/Key Laboratory of Animal GeneticsBreeding and Reproduction of Shaanxi ProvinceCollege of Animal Science and TechnologyNorthwest A&F UniversityYangling 712100China Animal Genomics ETH ZürichZürich 8092Switzerland Institute of Animal Science Tibet Academy of Agricultural and Animal Husbandry SciencesLhasa 850009China school of Biological and Pharmaceutical engineering Lanzhou Jiaotong UniversityLanzhou 730070China College of Life Sciences Shaanxi Normal UniversityXi’an 710119China Zoology and Evolutionary Biology Department of BiologyUniversity of Konstanz78457 KonstanzGermany College of Life and Geographic Sciences Kashi UniversityKashi 844000China Beijing Key Laboratory of Captive Wildlife Technologies Beijing ZooBeijing 100044China Department of Medical Research Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Key Laboratory of Agricultural Internet of Things Ministry of Agriculture and Rural Affairs/Shaanxi Key Laboratory of Agricultural Information Perception and Intelligent ServiceCollege of Information EngineeringNorthwest A&F UniversityYangling 712100China Institute of Animal Husbandry and Veterinary Medicine Xinjiang Academy of Agricultural and Reclamation SciencesShihezi 832000China State Key Laboratory of Sheep Genetic Improvement and Healthy Production Xinjiang Academy of Agricultural and Reclamation SciencesShihezi 832000China CAAS-ILRI Joint Laboratory on Livestock and Forage Genetic Resources Institute of Animal ScienceChinese Academy of Agricultural SciencesBeijing 100193China Livestock Genetics Program International Livestock Research InstituteNairobi 00100Kenya

Sheep were domesticated in the Fertile Crescent and then spread globally,where they have been encountering various environmental *** Tibetan sheep has adapted to high altitudes on the Qinghai-Tibet Plateau over the past 3000 *** explore genomic variants associated with high-altitude adaptation in Tibetan sheep,we analyzed Illumina short-reads of 994 whole genomes representing∼60 sheep breeds/populations at varied altitudes,PacBio High fidelity(HiFi)reads of 13 breeds,and 96 transcriptomes from 12 sheep *** testing between the inhabited altitudes and 34,298,967 variants was conducted to investigate the genetic architecture of altitude *** accurate HiFi reads were used to complement the current ovine reference assembly at the most significantly associatedβ-globin locus and to validate the presence of two haplotypes A and B among 13 sheep *** haplotype A carried two homologous gene clusters:(1)HBE1,HBE2,HBB-like,and HBBC,and(2)HBE1-like,HBE2-like,HBB-like,and HBB;while the haplotype B lacked the first *** high-altitude sheep showed highly frequent or nearly fixed haplotype A,while the low-altitude sheep dominated by haplotype *** further demonstrated that sheep with haplotype A had an increased hemoglobin–O2 affinity compared with those carrying haplotype *** highly associated genomic region contained the EGLN1 gene which showed varied expression between high-altitude and low-altitude *** results provide evidence that the rapid adaptive evolution of advantageous alleles play an important role in facilitating the environmental adaptation of Tibetan sheep.

关键词： environmental adaptation High altitude Hypoxia Selection signature Sheep

低温等离子体耦合Fe^(2+)均相催化降解甲苯和丙酮

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中国环境科学 2024年第2期44卷 670-678页

作者：刘蓉蓉秦彩虹姜超超黄家玉张鹏西安建筑科技大学环境与市政工程学院陕西西安710055 中国环境科学研究院北京100012

本文对比研究了两类典型VOCs(甲苯和丙酮)在单独NTP、NTP+LC/Fe^(2+)和NTP+LC/Fe^(2+)+PCA系统的降解效果.结果表明,甲苯和丙酮的去除率均随放电电压的升高而升高;在相同电压下,甲苯降解效率高于丙酮,但降解过程中O_(3)的产生量相当;当... 详细信息

本文对比研究了两类典型VOCs(甲苯和丙酮)在单独NTP、NTP+LC/Fe^(2+)和NTP+LC/Fe^(2+)+PCA系统的降解效果.结果表明,甲苯和丙酮的去除率均随放电电压的升高而升高;在相同电压下,甲苯降解效率高于丙酮,但降解过程中O_(3)的产生量相当;当放电电压为22kV时,NTP+LC/Fe^(2+)+PCA系统的甲苯去除效率比单独NTP提高了18.2%,丙酮的去除效率提高了55.5%;NTP+LC/Fe^(2+)+PCA的O_(3)去除率可达100%;EPR和猝灭实验表明,羟基自由基和超氧自由基在LC/Fe^(2+)+PCA反应器中对VOCs去除有重要贡献.最后,结合测定的自由基和中间有机产物,推测了VOCs在NTP+LC/Fe^(2+)体系中的降解途径.

关键词：甲苯丙酮低温等离子体均相催化亚铁离子

ABE-induced PDGFD start codon silencing unveils new insights into the genetic architecture of sheep fat tails

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Journal of Genetics and Genomics 2023年第12期50卷 1022-1025页

作者： Peter Kalds Shuhong huang Shiwei Zhou Siyuan xi Yumeng Fang Yawei Gao Kexin Sun chao Li Bei Cai Yao Liu Yige Ding Qifang Kou Tad Sonstegard Bjöm Petersen Stephen Kemp Baohua Ma Jian-lin Han Yulin Chen xiaolong Wang International Joint Agriculture Research Center for Animal Bio-breeding Ministry of Agriculture and Rural Affairs/Key Laboratory of Animal GeneticsBreeding and Reproduction of Shaanxi ProvinceCollege of Animal Science and TechnologyNorthwest A&F UniversityYanglingShaanxi 712100China Department of Animal and Poultry Production Faculty of Environmental Agricultural SciencesArish UniversityEl-Arish 45511Egypt College of Veterinary Medicine Northwest A&F UniversityYanglingShaanxi 712100China Key Laboratory of Ruminant Molecular and Cellular Breeding School of AgricultureNingxia UniversityYinchuanNingxia 750000China Ningxia Tianyuan Tan Sheep Farm HongsibuNingxia 751999China Acceligen Inc. St.PaulMN 55104United States International Livestock Research Institute(ILRI) Nairobi 30709-00100Kenya International Livestock Research Institute(ILRI) Nairobi 30709-00100Kenya CAAS-ILRI Joint Laboratory on Livestock and Forage Genetic ResourcesInstitute of Animal ScienceChinese Academy of Agricultural Sciences(CAAS)Beijing 100193China Key Laboratory of Livestock Biology Northwest A&F UniversityYanglingShaanxi 712100China Institute of Farm Animal Genetics Friedrich-Loeffler-lnstitutMarienseeNeustadt am Rubenberge 31535Germany

Sheep is an important livestock species raised globally to produce meat,milk,wool,and other *** the Neolithic Revolution,sheep were domesticated in the Fertile Crescent of Southwest Asia around 10,000 years ago(Chessa... 详细信息

关键词： products. globally raised

强效电化学-臭氧耦合工艺的渗滤液深度处理特性

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土木与环境工程学报（中英文） 2024年第4期46卷 231-240页

作者：郭雨阁杨超金鑫金鹏康西安建筑科技大学安德学院西安710311 西安建筑科技大学资源工程学院西安710311 西安建筑科技大学环境与市政工程学院西安710311 西安交通大学人居环境与建筑工程学院西安710049

以垃圾渗滤液二级出水非膜法深度处理为目的,构建以复合式阴极和形稳阳极为核心的强效电化学反应单元,其中复合式阴极由磁铁棒、碳毡和铁粉组成,起到Fe2+的析出和渗滤液中硝态氮的还原作用;形稳阳极为商用Ti/RuO2-IrO2电极,起到活化渗... 详细信息

以垃圾渗滤液二级出水非膜法深度处理为目的,构建以复合式阴极和形稳阳极为核心的强效电化学反应单元,其中复合式阴极由磁铁棒、碳毡和铁粉组成,起到Fe2+的析出和渗滤液中硝态氮的还原作用;形稳阳极为商用Ti/RuO2-IrO2电极,起到活化渗滤液中Cl-、产生活性氯、氧化去除渗滤液中氨氮和有机物的作用,并将二者的强效电化学反应与臭氧氧化作用于同一单元,构建了强效电化学-臭氧耦合工艺,以此强化渗滤液二级出水有机物和总氮的去除。结果表明,耦合工艺在电流强度为1.5 A、初始p H值为7、铁粉吸附密度为0.42 g/cm^(2)、臭氧投加量为4.58 mg/min时,对COD及TN的去除率分别为46.46%和81.70%。通过红外光谱(FT-IR)、电子顺磁共振波谱(EPR)、循环伏安曲线(CV)探究工艺对有机物的反去除机理,结果表明,耦合工艺中产生了·OH与·Cl多种活性物质,强化了渗滤液中脂肪族、酯、醚、酚等有机物的去除,提高了渗滤液的可生化性。耦合工艺与SBR小型生化系统联用后出水达到《生活垃圾填埋场污染控制标准》(GB 16889-2008)要求。

关键词：垃圾渗滤液深度处理电化学-臭氧耦合复合阴极

Two gap-free reference genomes and a global view of the centromere architecture in rice

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Molecular Plant 2021年第10期14卷 1757-1767页

作者： Jia-Ming Song Wen-Zhao xie Shuo Wang Yi-xiong guo Dal-Hoe Koo Dave Kudrna Chenbo Gong Yicheng huang Jia-Wu Feng Wenhui Zhang Yong Zhou Andrea Zuccolo Evan Long Seunghee Lee Jayson Talag Run Zhou xi-Tong Zhu Daojun Yuan Joshua Udall Weibo xie Rod AWing Qifa Zhang Jesse Poland Jianwei Zhang ling-ling Chen National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070China College of Life Science and technology Guangxi UniversityNanning 530004China Wheat Genetics Resource Center Department of Plant PathologyKansas State UniversityManhattanKSUSA Arizona Genomics Institute School of Plant SciencesUniversity of ArizonaTucsonAZ 85721USA Center for Desert Agriculture Biological and Environmental Sciences&Engineering Division(BESE)King Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Saudi Arabia Plant and Wildlife Science Department Brigham Young UniversityProvoUT 84602USA International Rice Research Institute(IRRI) Strategic InnovationLos Baños4031 LagunaPhilippines Crop Germplasm Research Unit USDA-ARS2881 F&B RoadCollege StationTX 77845USA

Rice(Oryza sativa),a major staple throughout the world and a model system for plant genomics and breeding,was the first crop genome sequenced almost two decades ***,reference genomes for all higher organisms to date contain gaps and missing ***,we report the assembly and analysis of gap-free reference genome sequences for two elite *** xian/indica rice varieties,Zhenshan 97 and Minghui 63,which are being used as a model system for studying heterosis and ***-free reference genomes provide the opportunity for a global view of the structure and function of *** show that all rice centromeric regions share conserved centromere-specific satellite motifs with different copy numbers and *** addition,the similarity of CentO repeats in the same chromosome is higher than across chromosomes,supporting a model of local expansion and *** genomes have over 395 non-TE genes located in centromere regions,of which∼41%are actively *** large structural variants at the end of chromosome 11 affect the copy number of resistance genes between the two *** availability of the two gap-free genomes lays a solid foundation for further understanding genome structure and function in plants and breeding climate-resilient varieties.

关键词： rice genome ZS97 MH63 hybrid rice centromere architecture

Comparisons of the film peeling from the composite oxides of quartz sand filters using ozone, hydrogen peroxide and chlorine dioxide

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Journal of environmental Sciences 2015年第8期27卷 20-27页

作者： Yingming guo tinglin huang Gang Wen xin Cao school of environmental and municipal engineering Xi'an University of Architecture and Technology

To solve the problem of shortened backwashing intervals in groundwater plants, several disinfectants including ozone（O3）, hydrogen peroxide（H2O2） and chlorine dioxide（Cl O2）were examined to peel off the film from the quartz sand surface in four pilot-scale *** optimized oxidant dosage and oxidation time were determined by batch ***, the optimized conditions were tested in the four pilot-scale columns. The results demonstrated that the backwashing intervals increased from 35.17 to 54.33（H2O2）and to 53.67 hr（ClO2） after the oxidation treatments, and the increase of backwashing interval after treatment by O3 was much less than for the other two ***, the treatment efficiency of filters was not affected by O3 or H2O2 oxidation;but after oxidation by ClO2, the treatment efficiency was deteriorated, especially the ammonia removal（from 96.96% to 24.95%）. The filter sands before and after the oxidation were characterized by scanning electron microscopy and X-ray photoelectron *** with the oxidation by O3 and H2O2, the structures on the surface of filter sands were seriously damaged after oxidation by ClO2. The chemical states of manganese on the surfaces of those treated sands were only changed by ClO2. The damage of the structures and the change of the chemical states of manganese might have a negative effect on the ammonia removal. In summary, H2O2 is a suitable agent for film peeling.

关键词： Pilot-scale Ozone Hydrogen peroxide Chlorine dioxide Backwashing interval

基于CPSONN-BP的校园节能减排数据融合

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绿色科技 2024年第6期26卷 256-264页

作者：边超黄光球惠巧娟银川科技学院信息工程学院宁夏银川750021 西安建筑科技大学管理学院陕西西安710055

随着全球气候变化加剧,碳排放和能源消耗成为国际关注的焦点。在“双碳”目标背景下,高校节能减排的重要性日益凸显。基于此,研究了一种基于混沌粒子群优化的BP神经网络(CPSONN-BP)模型,用于校园节能减排数据的有效融合和分析。该模型... 详细信息

随着全球气候变化加剧,碳排放和能源消耗成为国际关注的焦点。在“双碳”目标背景下,高校节能减排的重要性日益凸显。基于此,研究了一种基于混沌粒子群优化的BP神经网络(CPSONN-BP)模型,用于校园节能减排数据的有效融合和分析。该模型利用多源异构数据,旨在建立一个精准综合的高校节能减排预测模型,以更有效应对双碳背景下的能源挑战和环境压力。通过对CPSONN-BP模型在校园节能减排数据融合方面的性能进行综合比较研究,发现该模型在准确度、收敛速度、稳定性和处理复杂数据能力上具有显著优势。与传统Excel预测方法和标准BP神经网络相比,CPSONNBP模型在处理多变量和非线性问题时表现出更快的收敛速度和更高的预测准确性。该模型在多次运行中表现出高度的可靠性和一致性,特别适用于解析高度非线性和多变量特征的数据。研究展示了CPSONN-BP模型在校园节能减排数据融合方面的优越性能,对于促进可持续发展,实现经济、环境和社会的协调发展具有重要意义。

关键词：高校节能减排能源消耗预测模型多源异构数据数据融合

First-principles study of magnetism of 3d transition metals and nitrogen co-doped monolayer MoS2

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Chinese Physics B 2020年第9期29卷 450-457页

作者： Long lin Yi-Peng guo chao-Zheng He Hua-Long Tao Jing-Tao huang Wei-Yang Yu Rui-xin Chen Meng-Si Lou Long-Bin Yan Cultivating Base for Key Laboratory of Environment-Friendly Inorganic Materials in Henan Province School of Materials Science and EngineeringHenan Polytechnic UniversityJiaozuo 454000China Institute of environmental and Energy Catalysis School of Materials Science and Chemical EngineeringXi'an Technological UniversityXi'an 710021China Liaoning Key Materials Laboratory for Railway School of Materials Science and EngineeringDalian Jiaotong UniversityDalian 116028China school of Physics and Electronic Information engineering Henan Polytechnic UniversityJiaozuo 454003China

The electronic structures and magnetic properties of diverse transition metal (TM=Fe, Co, and Ni) and nitrogen (N) co-doped monolayer MoS2 are investigated by using density functional theory. The results show that the intrinsic MoS2 does not have magnetism initially, but doped with TM (TM=Fe, Co, and Ni) the MoS2 possesses an obvious magnetism distinctly. The magnetic moment mainly comes from unpaired Mo:4d orbitals and the d orbitals of the dopants, as well as the S:3p states. However, the doping system exhibits certain half-metallic properties, so we select N atoms in the V family as a dopant to adjust its half-metal characteristics. The results show that the (Fe, N) co-doped MoS2 can be a satisfactory material for applications in spintronic devices. On this basis, the most stable geometry of the (2Fe-N) co-doped MoS2 system is determined by considering the different configurations of the positions of the two Fe atoms. It is found that the ferromagnetic mechanism of the (2Fe-N) co-doped MoS2 system is caused by the bond spin polarization mechanism of the Fe-Mo-Fe coupling chain. Our results verify that the (Fe, N) co-doped single-layer MoS2 has the conditions required to become a dilute magnetic semiconductor.

关键词： MoS2 first principle calculations diluted magnetic semiconductors magnetic property

NOGEA: A Network-oriented Gene Entropy Approach for Dissecting Disease Comorbidity and Drug Repositioning

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Genomics, Proteomics & Bioinformatics 2021年第4期19卷 549-564页

作者： Zihu guo Yingxue Fu chao huang Chunli Zheng Ziyin Wu Xuetong Chen Shuo Gao Yaohua Ma Mohamed Shahen Yan Li Pengfei Tu Jingbo Zhu Zhenzhong Wang Wei xiao Yonghua Wang College of Life Science Northwest UniversityXi'an 710069China College of Life Science Northwest A&F UniversityYangling 712100China Zoology Department Faculty of ScienceTanta UniversityTanta 31527Egypt Key Laboratory of Industrial Ecology and environmental engineering(Ministry of Education) Faculty of ChemicalEnvironmental and Biological Science and TechnologyDalian University of TechnologyDalian 116024China State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China school of Food Science and technology Dalian Polytechnic UniversityDalian 116034China State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process Lianyungang 222001China

Rapid development of high-throughput technologies has permitted the identification of an increasing number of disease-associated genes(DAGs),which are important for understanding disease initiation and developing precision ***,DAGs often contain large amounts of redundant or false positive information,leading to difficulties in quantifying and prioritizing potential relationships between these DAGs and human *** this study,a networkoriented gene entropy approach(NOGEA)is proposed for accurately inferring master genes that contribute to specific diseases by quantitatively calculating their perturbation abilities on directed disease-specific gene *** addition,we confirmed that the master genes identified by NOGEA have a high reliability for predicting disease-specific initiation events and progression *** genes may also be used to extract the underlying information of different diseases,thus revealing mechanisms of disease *** importantly,approved therapeutic targets are topologically localized in a small neighborhood of master genes in the interactome network,which provides a new way for predicting drug-disease *** this method,11 old drugs were newly identified and predicted to be effective for treating pancreatic cancer and then validated by in vitro ***,the NOGEA was useful for identifying master genes that control disease initiation and co-occurrence,thus providing a valuable strategy for drug efficacy screening and *** codes are publicly available at https://***/guozihuaa/NOGEA.

关键词： Systems pharmacology Gene entropy Disease gene network Disease comorbidity Drug repositioning