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FOUR NEW TAXOIDS FROM THE NEEDLES OF TAXUS WALLICHIANA ZUCC

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Chinese Chemical Letters 1995年第11期6卷 971-974页

作者： Zhang, jz Fang, QC Liang, XT Kong, M He, WY Chinese Acad Med Sci Inst Mat Med Beijing 100050 Peoples R China Beijing Union Med Coll Beijing 100050 Peoples R China

Four new taxoids with rearranged taxane skeleton,named taxawallins C(1),D(2), F(3)and H(4),were isolated from the needles of Taxus wallichiana Zucc.. Their structures were elucidated by spectroscopic techniques.

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SYNTHESIS OF MESOPOROUS CHROMIUM SILICATE

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Chinese Chemical Letters 1995年第12期6卷 1091-1094页

作者： Yuan, ZY Chen, TH Wang, jz Li, HX Liu, SQ Nankai Univ Dept Chem Catalysis Lab Tianjin 300071 Peoples R China Nankai Univ Catalyst Plant Tianjin 300071 Peoples R China

A mesoporous chromium silicate molecular sieve with MCM-41 structure has beers prepared by direct hydrothermal synthesis; XRD; framework IR, ESR and DR-UV spectroscopies provided evidence of the presence of framework ...

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Synthesis and characteristics of nitric oxide spin probes

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Chinese Science Bulletin 1997年第20期42卷 1693-1699页

作者： Zhao, HT Liu, L Zhang, jz Cong, JB Wu, K Sun, CP Univ Sci & Technol China Grad Sch Dept Chem Beijing 100039 Peoples R China

NITRIC oxide (NO) is the important cell messenger molecule that regulates the central ner-vous, cardiovascular, endocrine and immunity systems. The study of NO not only canexplain many physiological phenomena, but also can provide new ways to prevent and treat alot of diseases. However, at present, most of the methods for assaying NO produced by or-ganism have some defects, for example, low sensitivity, no specificity, no convenience.

关键词： imidazole analogs nitrozide radical NO spin probe ESR.

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分子生物学方法在微生物生态学中的应用

中山大学学报（自然科学版） 1998年第2期37卷 97-101页

作者：夏北成 Zhou,jz 中山大学环境科学研究所

给出了植被对微生物群落结构影响的研究结果，同时较详细地介绍了从土壤样品中提取ＤＮＡ以及对ＤＮＡ进行克隆，并获得微生物克隆群落的方法和步骤．应用该方法在获得高产量ＤＮＡ的同时，获得了多样性极高的微生物克隆群落．

关键词：微生物群落多样性分子生物学微生物生态学

TRH microinjection into DVC enhances motility of rabbits gallbladder via vagus nerve

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World Journal of Gastroenterology 1998年第2期4卷 70-72页

作者： Liu, CY Liu, jz Zhou, JH Wang, HR Li, ZY Li, AJ Liu, KJ Shandong Univ Dept Physiol Jinan 250012 Shandong Peoples R China

AIM To investigate the effects of TRH in DVC on motility of the gallbladder in rabbits. METHODS After fasted for 15h - 18h , rabbits were anesthetized with urethane (1 0g/kg) . Gallbladder pressure (GP) was measured by a frog bladder perfused with normal saline. RESULTS After microinjection of TRH (8 8nmol, 1μl ) into DVC, GP was raised and the frequency of phasic contraction of gallbladder (FPCGB) increased. All the doses of TRH (0 13, 0 25, 0 50, 0 80, 1 30nmol , 1μl ) injected into DVC could excite the motility of gallblader. As the dose of TRH was enlarged, the amplitude and duration of the reaction increased. Effects of TRH in DVC on motility of the gallbladder could be completely abolished by atropine ( 0 2mg/g , i.v.) or vagotomy, but could not be inhibited by phentolamine iv (1 5mg/g) or propranolol iv (1.5mg/g) or by transecting the spinal cord. CONCLUSION Thyrotropin releasing hormone in DVC can excite motility of gallbladder. This effect was mediated by vagus nerves and peripheral M receptor. Its physiological significance may be related to maintaining the phasic contraction of gallbladder in interdigestive period.

关键词： gallbladder vagus nerve dorsal vagal complex thyrotropin releasing hormone cholinergic M receptors rabbits

Study on Speciation of Pr(III) in Human Blood Plasma by Computer Simulation

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Chinese Chemical Letters 2000年第3期11卷 263-264页

作者： Liu, YM Han, JF Wu, ZJ Wang, Y Yang, KY Niu, CJ Ni, jz Chinese Acad Sci Changchun Inst Appl Chem Lab Rare Earth Chem & Phys Changchun 130022 Peoples R China

Speciation of Pr(III) in human blood plasma has been investigated by computer simulation. The speciation and distribution of Pr(III) has been obtained. It has been found that most of Pr(III) is bound to phosphate and ... 详细信息

关键词： speciation praseodymium(III) computer simulation

Expression of heavy-chain variable domain of mAb against Encephalitis Type B virus in transgenic tobacco

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Chinese Science Bulletin 1997年第12期42卷 1038-1041页

作者： Wu, YQ Xiong, XM Zeng, jz Zhang, J Wang, DJ Huang, HL Institute of Genetics Chinese Academy of Sciences Beijing China

SINCE the first report on immunoglobulin gene expression in plant by Hiatt et al. in 1989,analogous researches have been further developed. Up to now, it has become a new method touse transgenic plants and plant cells to produce antibodies and study disease-resistance breedingof crops, plant metabolism and growth, which is an organic combination of immunologyand plant sciences at molecular level. According to recent reports, both higher and lowerplants, such as tobacco, Arabidopsis, calli of maize and unicellular green alga, can

关键词： immunoglobulin heavy-chain variable domain gene expression tobacco.

Synthesis,Structure and Hydrogenation Property of trans-PdCl_(2){Ph_(2)P[o-C_(6)H_(4)CH(OC_(2)H_(5))_(2)]}_(2)

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Chemical Research in Chinese Universities 1997年第4期13卷 117-120页

作者： Xu, PP Gao, JX Zhou, ZH Wang, jz Chen, Z Hu, SZ Wan, HL XIAMEN UNIV DEPT CHEMSTATE KEY LAB PHYS CHEM SOLID SURFACEXIAMEN 361005PEOPLES R CHINA XIAMEN UNIV INST PHYS CHEMXIAMEN 361005PEOPLES R CHINA

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Ｓｙｎｔｈｅｓｉｓ，ＳｔｒｕｃｔｕｒｅａｎｄＨｙｄｒｏｇｅｎａｔｉｏｎＰｒｏｐｅｒｔｙｏｆｔｒａｎｓ┐ＰｄＣｌ２｛Ｐｈ２Ｐ［ｏ┐Ｃ６Ｈ４ＣＨ（ＯＣ２Ｈ５）２］｝２＊ＸＵＰｉａｎ－ｐｉａｎ，ＧＡＯＪｉｎｇ－ｘｉｎｇ＊＊，ＺＨＯＵＺｈａｏ－ｈｕｉ，ＷＡＮ...

关键词： Palladium complex Hydrogenation Crystal structure

3D－QSAR　STUDY　ON　HUPERZINE　A　ANALOGS　WITH　MOLECULAR　MODELING　AND　COMPARATIVE　MOLECULAR　FIELD　ANALYSIS（COMFA）　METHODS

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Chinese Chemical Letters 1996年第3期7卷 253-256页

作者： Jiang, HL Chen, KX Chen, jz Tang, Y Wang, QM Li, Q Shen, X Ji, RY CHINESE ACAD SCI SHANGHAI INST MAT MEDSHANGHAI 200031PEOPLES R CHINA

On the basis of conformational search for ten huperzine A analogs according to the structure ofAChE active site witll our approach BCSPL,we performed a 3D-QSAR analysis for these compounds usingmolecular modeling and CoMFA method. The calculation results can be used to explain the relationshipbetween the structUre properties and the activities.

关键词： QSAR STUDY ON HUPERZINE ANALYSIS ANALOGS