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Bactericidal Effect and Clinical Application of 20% Sodium Dichloroisocyanurate Powder

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Agricultural Biotechnology 2022年第5期11卷 50-53页

作者： Chengxin LYU Youjiang DIAO shijin guo Shandong Agriculture and Engineering University Jinan 250100China Shandong Binzhou Animal Science and Veterinary Medicine Academy Binzhou 256600China Shandong Lvdu Ante Veterinary Drug Industry Binzhou 256600China

[Objectives]This study was conducted to investigate the formulation stability of 20% sodium dichloroisocyanurate powder and its killing effect on common pathogenic bacteria in the animal breeding environment and to provide a scientific basis for veterinary clinical application. [Methods] The stability of 20% sodium dichloroisocyanurate powder was tested through an accelerated test and a long-term test. In the accelerated test, 20% sodium dichloroisocyanurate powder and sodium hypochlorite were stored in 37 ℃ constant temperature incubators for 90 d, and the available chlorine contents were compared. In the long-term test, 20% sodium dichloroisocyanurate powder was sealed and stored at room temperature, and its effective chlorine content and pH were measured regularly. In order to test its bactericidal effect in clinical use, 20% sodium dichloroisocyanurate powder, lime milk and 5% dilute glutaraldehyde solution were sprayed in groups to disinfect empty sheds in a pig farm, and the total colony count, Escherichia coli colony count, Staphylococcus aureus colony count and fungal colony count were used as testing indexes to comprehensively evaluate the disinfection effects on microorganisms in the air of the empty sheds and the surface of objects inside the sheds after disinfection. [Results] The 20% sodium dichloroisocyanurate powder had an available chlorine loss rate of 7.92% in the accelerated test, and the loss rates of available chlorine content and pH of 20% sodium dichloroisocyanurate powder in the long-term test(240 d) were 1.52% and 1.87% at room temperature, respectively. In the test to detect the sterilization effects on the pig farm, the total colony count, E. coli colony count, S. aureus colony count and fungal colony count of samples treated with 20% sodium dichloroisocyanurate powder were lower than those of other two groups(P<0.05), and the total colony count of samples disinfected with 20% sodium dichloroisocyanurate powder after cleaning the dirt was

关键词： Sodium dichloroisocyanurate Stability Disinfection Clinic application

一元二氧化氯消毒颗粒对水生动物药理及毒理学研究

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河北渔业 2007年第4期 12-15页

作者：郭时金沈志强张颖山东省滨州畜牧兽医研究院山东滨州256600 山东绿都安特动物药业有限公司山东滨州256618

在水产养殖方面对一元二氧化氯消毒颗粒的药理学及毒理学进行了试验。运用试管稀释法和半静水法药浴方式测定了一元二氧化氯消毒颗粒对水生动物常见致病菌的最小抑菌浓度（MIC）及半致死浓度（LC50）。试验结果表明：一元二氧化氯消毒... 详细信息

在水产养殖方面对一元二氧化氯消毒颗粒的药理学及毒理学进行了试验。运用试管稀释法和半静水法药浴方式测定了一元二氧化氯消毒颗粒对水生动物常见致病菌的最小抑菌浓度（MIC）及半致死浓度（LC50）。试验结果表明：一元二氧化氯消毒颗粒对海水养殖动物主要致病菌具有明显的抑制作用，MIC为0．75～3．0μg／mL（以ClO2计）。在使用浓度下，一元二氧化氯消毒颗粒对黑鲷、河蟹、大型蚤及卤虫无节幼体存活和生长影响不显著，毒副作用不明显。

关键词：水产养殖一元二氧化氯消毒颗粒最小抑菌浓度(MIC) 半数致死浓度(LC50)

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集装箱后方堆场信息化建设探讨

集装箱化 2001年第10期12卷 33-34页

作者：王富荣郭世津天津港东方发展公司天津300456

集装箱后方堆场是相对集装箱码头堆场而言的码头功能延伸、补充和配套服务的设施,在港口的集装箱运输中发挥着十分重要的作用.当前集装箱后方堆场的信息化建设滞后于码头堆场.笔者在天津港东方发展公司集装箱后方堆场业务管理软件投入... 详细信息

集装箱后方堆场是相对集装箱码头堆场而言的码头功能延伸、补充和配套服务的设施,在港口的集装箱运输中发挥着十分重要的作用.当前集装箱后方堆场的信息化建设滞后于码头堆场.笔者在天津港东方发展公司集装箱后方堆场业务管理软件投入运行的实践基础上,分析堆场存在问题,提出解决方法.

关键词：集装箱码头堆场信息化集装箱运输港口工程

Disinfection Effects and Clinical Application of Sodium Dichloroisocyanurate Powder on Bacteria

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Agricultural Biotechnology 2022年第4期11卷 57-60页

作者： shijin guo Ling LI Qing LI Jingjing ZHOU Chengxin LYU Lanying guo Zhiqiang SHEN Shandong Binzhou Animal Science and Veterinary Medicine Academy Binzhou 256600China Shandong Lvdu Ante Veterinary Drug Industry Binzhou 256600China Changyi Animal Husbandry Development Center Weifang 261300China Shandong Agriculture and Engineering University Jinan 250100China

With the continuous increase of large-scale pig farms,the disinfection of pig farm environment plays an extremely important part in the control and prevention of pig farm diseases in high-density breeding *** an important breeding place for pig farms,the farrowing house must be performed with scientific and standardized *** this paper,different disinfection modes were used to disinfect the empty farrowing houses of pig farms,and the total plate count,Escherichia coli,Staphylococcus aureus,and fungi were used as detection indicators to comprehensively evaluate the disinfection effect of the air microorganisms and the surface of the objects in the empty house after disinfection,with the aim to provide a basis for the establishment of a scientific pig farm environmental disinfection model.

关键词： Sodium dichloroisocyanurate powder Bacteria Disinfection effect Pig farm Clinical application

Harms of Mycotoxins to Animals and Research Progress of Detection Methods

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Animal Husbandry and Feed Science 2022年第4期14卷 21-24页

作者： guo shijin Zhang Zhimei Tang Shiyun Fu Shijun Li Ling Shen Zhiqiang Shandong Binzhou Animal Science&Veterinary Medicine Academy Binzhou 256600China Shandong Lvdu Ante Veterinary Drug Industry Co. Ltd.Binzhou 256600China

Mycotoxin is widely distributed in various feedstuffs and feeds of *** not only causes feed deterioration,but also leads to various diseases of animals,or even results in acute toxic death,causing great harm to the breeding *** this paper,the harm of mycotoxin to animals and its detection methods in feed and animals are summarized and analyzed,so as to provide the reference basis for further improving the detection methods of mycotoxin and reducing the harm of mycotoxin to breeding industry.

关键词： Mycotoxin Harm Detection method

Application Research Progress of Amino Acid Chelated Iron in Pig Nutrition

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Animal Husbandry and Feed Science 2022年第4期14卷 37-40页

作者： guo shijin Zhang Zhimei Fu Shijun Wang Jianjun Tang Shiyun Shen Zhiqiang Shandong Binzhou Animal Science&Veterinary Medicine Academy Binzhou 256600China Shandong Lvdu Ante Veterinary Drug Industry Co. Ltd.Binzhou 256600China

As an essential trace element for pigs,iron is very important for pig production,and plays an important role in sow performance,growth and development of piglets,metabolic process and physiological defense[1-3].Iron is a cofactor of catalase in the body’s anti-oxidation system,which plays an important role in preventing lipid oxidation and maintaining meat *** is an indispensable activator of enzymes involved in redox reaction,such as superoxide dismutase(SOD).

关键词： Iron system element

Mutation Breeding of Lactobacillus and Its Application in Yoghurt

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Agricultural Biotechnology 2023年第1期12卷 31-34页

作者： Xin LI Shiyun TANG Fengrong TIAN Bing ZHANG Shijun FU shijin guo Shandong Binzhou Animal Science&Veterinary Medicine Academy Binzhou 256600China Shandong Anyouxian Food Co. Ltd.Binzhou 256600China Shandong Lvdu Ante Veterinary Drug Industry Binzhou 256600China

With the gradual improvement of the quality of people’s life, the disorder of lipid metabolism caused by high-fat diet has become the main reason that affects the health of our people. Hyperlipidemia, hypertension and hyperglycemia have the effect of causing a large number of serious complications, and are also the main factors of cardiovascular disease. Lactic acid bacteria can avoid hyperlipidemia by inhibiting the excessive growth of harmful intestinal bacteria, maintaining the balance of intestinal microecology, absorbing intestinal cholesterol and regulating lipid metabolism. Therefore, this paper focused on the mutation and breeding of Lactobacillus, and analyzed its application in yoghurt, aiming to provide reference for relevant researchers.

关键词： Lactobacillus Mutation breeding Yogurt Application

Role and Effects of Eucommia ulmoides Leaves in the Growth Process of Livestock and Poultry

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Agricultural Biotechnology 2023年第5期12卷 43-45页

作者： shijin guo Ling LI Xin LI Yi ZHANG Jianjun WANG Lei ZHAO Yanping WANG Lu guo Shijun FU Shandong Binzhou Animal Science&Veterinary Medicine Academy Binzhou 256600China Shandong Lvdu Ante Veterinary Drug Industry Binzhou 256600China

Substitutes of feed antibiotics have been a key research topic in the new stage of animal *** veterinary medicine refers to decoction pieces and their preparations processed from natural plants,animals,and minerals and used for animal disease prevention and improvement of animal production performance under the guidance of Chinese veterinary pharmacy *** ulmoides leaf extract has many active functional components such as chlorogenic acid,*** polysaccharides and flavonoids,which have many biological properties such as antibacterial,antioxidant,immune-regulation,sugar ester-and bone metabolism-regulation *** paper explored active ingredients and biological properties of *** leaf extract,as well as its role and effects in livestock and poultry breeding,providing a scientific basis for the use of *** leaves in livestock and poultry breeding.

关键词： Eucommia ulmoides leaves Livestock and poultry farming Role Efficacy

小G蛋白抑制剂CASIN的体外抗真菌活性研究

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中国真菌学杂志 2022年第4期17卷 289-293页

作者：巢雯邓忠宇郭士槿郭熠凡阎澜邱丽娟吕权真海军军医大学基础医学院上海200433 海军军医大学药学院上海200433

目的通过对小G蛋白抑制剂体外抗真菌活性的测定,筛选具有新结构类型的抗真菌活性化合物。方法采用微量液基稀释法考察不同小G蛋白抑制剂对于念珠菌的最低抑菌浓度(MIC),并从中筛选活性较强的化合物进一步进行抗真菌谱测定;采用时间-生... 详细信息

目的通过对小G蛋白抑制剂体外抗真菌活性的测定,筛选具有新结构类型的抗真菌活性化合物。方法采用微量液基稀释法考察不同小G蛋白抑制剂对于念珠菌的最低抑菌浓度(MIC),并从中筛选活性较强的化合物进一步进行抗真菌谱测定;采用时间-生长曲线和时间-杀菌曲线考察CASIN对于白念珠菌生长增殖的影响;采用菌丝诱导实验考察化合物CASIN对于白念珠菌菌丝形成的抑制效果;采用甲基四氮盐(XTT)法考察化合物CASIN对于白念珠菌生物被膜形成的抑制作用。结果在考察的小G蛋白抑制剂中,CASIN的体外抗真菌活性最强,对于近平滑念珠菌、克柔念珠菌、热带念珠菌、光滑念珠菌中均有较好的抑制作用,MIC为8~16μg/mL。16μg/mL CASIN可以有效抑制YPD培养基中白念珠菌的生长增殖,也在RPMI1640培养基中展现出对白念珠菌的杀菌活性;当培养基中CASIN浓度高于8μg/mL时,白念珠菌菌丝受到明显抑制;此外,8μg/mL的CASIN浓度对于白念珠菌的被膜生成具有80%以上的抑制率。结论小G蛋白抑制剂CASIN具有较强的体外抗念珠菌活性。

关键词：小G蛋白 CASIN 抗真菌活性