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Stress Distribution in Composites with Co-Phase Periodically Curved Two Neighboring Hollow Fibers

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Computers, Materials & Continua 2021年第10期69卷 967-983页

作者： Resat Kosker Ismail gulten Department of Mathematical Engineering Faculty of Chemistry and MetallurgyYildiz Technical UniversityDavutpasa CampusEsenler34220IstanbulTurkey Department of Mathematical Engineering Graduate School of Natural and Applied SciencesYildiz Technical UniversityDavutpasa CampusEsenler34220IstanbulTurkey

In this paper,stress distribution is examined in the case where infinite length co-phase periodically curved two neighboring hollow fibers are contained by an infinite elastic *** midline of the fibers is assumed to be in the same *** the three-dimensional geometric linear exact equations of the elasticity theory,research is carried out by use of the piecewise homogeneous body ***,the body is assumed to be loaded at infinity by uniformly distributed normal forces along the hollow *** the inter-medium between the hollow fibers and matrix surfaces,complete cohesion conditions are *** boundary form perturbation method is used to solve the boundary value *** this investigation,numerical results are obtained by considering the zeroth and first approximations to calculate the self-equilibrium shear stresses and normal stress at the contact surfaces between the hollow fibers and *** numerical results have been obtained and interpreted about the effects of the interactions between the hollow fibers on this distribution.

关键词： Hollow fibers stress distribution fibrous composite periodic curvature

Effects of COVID-19 fear and anxiety on attitudes towards complementary and alternative medicine use in women with gynecological cancer during the COVID-19 pandemic

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Journal of Integrative Medicine 2023年第4期21卷 377-384页

作者： Fatma Uslu-Sahan Ilknur Yesilcınar Gonul Kurt Elif Hancer gulten Guvenc Department of Obstetrics and Gynecologic Nursing Faculty of NursingHacettepe UniversityAnkara 06100Turkey Department of Obstetrics and Gynecologic Nursing Faculty of Health SciencesIzmir Katip Celebi UniversityIzmir 35620Turkey Department of Obstetrics and Gynecology Nursing Gulhane Faculty of NursingUniversity of Health SciencesAnkara 06018Turkey Department of Obstetrics and Gynecology Gynecologic Oncology ClinicHacettepe University Faculty of MedicineAnkara 06800Turkey

Objective:Patients with gynecological cancer commonly use complementary and alternative medicine(CAM)methods to cope with the ***,despite the existence of treatment strategies,the effect of fear and anxiety caused by coronavirus disease 2019(COVID-19)pandemic on attitudes about CAM use is *** study was carried out to investigate the effect of fear and anxiety experienced by patients with gynecological cancer during the COVID-19 pandemic on their attitudes towards the use of ***:This is a cross-sectional and descriptive study that included 177 women with gynecological cancer;participants were recruited from a social networking site for cancer patients in Turkey between June and December *** were collected using an online survey that included the Personal Information Form,the Fear of COVID-19 Scale,the Coronavirus Anxiety Scale,and the Attitude Towards Holistic Complementary and Alternative Medicine *** statistics,t-test,Pearson’s correlation test,and simple linear and multiple regression analyses were performed to analyze the ***:During the pandemic,55.4%of the participants reported using CAM methods,but only 22.6%were using CAM before the *** participants who used CAM during the pandemic also scored higher on the fear of COVID-19 and coronavirus anxiety scales(20.69±5.37 and 13.09±6.29,respectively)compared to the participants who did not use CAM(9.29±2.72 and 6.35±2.06,respectively).Fear of COVID-19 accounted for 52%of the CAM attitude score,while coronavirus anxiety accounted for 15%of the CAM attitude *** of COVID-19 and coronavirus anxiety together accounted for 53%of CAM ***:Gynecological cancer patients with high levels of COVID-19-related anxiety and fear during the pandemic used CAM *** that the psychological effects of the pandemic will continue in the coming years,CAM use should be evaluated as a coping strategy,especially due to the COVID-19-related anxiety an

关键词： Complementary and alternative medicine Anxiety COVID-19 Fear Gynecological cancer

Structure and seismo-tectonic investigation of the Sar?g?l-Buldan region,Western Anatolia,by using gravity and seismicity data

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Journal of Mountain Science 2022年第10期19卷 2758-2775页

作者： ALTINOGLU Fatma Figen POLAT gulten Department of Geological Engineering Faculty of EngineeringPamukkale UniversityDenizli 20017Turkey Department of Civil Engineering Yeditepe UniversityKayisdagi Cad 34755IstanbulTurkey

The parameter b(commonly referred to as the b-value)is one of the most significant seismic parameters to describe the seismicity of an investigated *** this study,the structural framework of the Sar?g?l-Buldan region located in the intersection area of the western Anatolian graben system in Turkey was investigated by using seismicity and gravity *** known,western Anatolia is one of the most seismically active regions of the Anatolian ***,seismic activity in this region is very *** of the Bouguer gravity data enabled to define the shallow subsurface structure of the study *** from the gravity analysis indicated that the sediment basement depth varied from 0.1 km and 2.1 *** also detected many NW-SE,E-W,and NESW trending lineaments that may be faults or fractures,and the NW-SE trending the Denizli basin lies to the east of the Ala?ehir *** observed that the findings from this analysis seem compatible with the regional geological *** addition to this,the seismicity of the region was analyzed by using the frequency-magnitude distribution to find out the seismic hazard *** most useful way in the analysis of the seismic hazard studies is to reveal the location of the earthquake boundary,which produces devastating big seismic events because such studies make it possible to forecast the location of possible future earthquakes and improve seismic hazard *** b-value for this study region was estimated by using the maximum likelihood *** in the b-value were observed,which range from≈0.2 to 2.A higher b-value was detected in the Buldan horst and surrounding *** contrast to this,lower bvalues were observed in the northeast part of the interaction region between the Denizli and the Ala?ehir *** positive Bouguer anomaly values as high as+10 m Gal and low b-values in the north-eastern part of the study region were interpreted as indicating a thinner crustal *** comparison,negative Bouguer a

关键词： Bouguer Gravity Seismicity Stress bvalue the Sar?g?l-Buldan region

Cytoprotective effects of amifostine,ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats

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World Journal of Gastroenterology 2014年第29期20卷 10158-10165页

作者： Sami Akbulut Hulya Elbe Cengiz Eris Zumrut Dogan gulten Toprak Emrah Otan Erman Erdemli Yusuf Turkoz Liver Transplant Institute Inonu University Faculty of Medicine Department of Histology and Embriology Inonu University Faculty of Medicine Department of Anatomy Adiyaman University Faculty of Medicine Department of Biochemistry Dicle University Faculty of Medicine Department of Biochemistry Inonu University Faculty of Medicine

AIM: To investigate the potential role of oxidative stress and the possible therapeutic effects of N-acetyl cysteine (NAC), amifostine (AMF) and ascorbic acid (ASC) in methotrexate (MTX)-induced hepatotoxicity.

关键词： Methotrexate Amifostine N-acetyl cysteine Ascorbic acid Hepatotoxicity Oxidative stress

One-year experience in the retinopathy of prematurity: frequency and risk factors, short-term results and follow-up

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International Journal of Ophthalmology(English edition) 2011年第6期4卷 634-640页

作者： Sariaydin Mehmet Atlihan Fusun Calkavur Sebnem Olukman Ozgur Ercan gulten Ozturk Arif Taylan Kaya Kilic Fatma Gokaslan Filiz Altinyaprak Derya Malatyali Rana Department of Neonatology Trabzon Medical Faculty Department of Neonatology Dr. Behet Uz Children's Hospital Department of Ophthalmology Dr. Behet Uz Children's Hospital

· AIM: As a result of the increase in premature births and the advances in neonatal intensive care, retinopathy of prematurity (ROP) remains one of the most important causes of childhood blindness worldwide. The main factors in the development of ROP are gestational age, birth weight and oxygen therapy. ROP continues to gain importance due to the increasing survival rates of more immature babies. · METHODS: Between January 2007 and October 2008, 203 premature infants treated at the Neonatal Intensive Care Unit (NNICU) were prospectively enrolled and the relationship between known risk factors and the occurance of ROP was studied. · RESULTS: ROP in various stages developed in 86 cases (42.4%). Statistically significant correlations were found between the development of ROP and birth weight (P < 0.0001) gestational age (P <0.0001), oxygen treatment and its duration (P <0.0001 and P =0.002), mechanical ventilation (MV) and its duration (P =0,0001 and P =0.0001), apnea(P = 0.001), intraventricular hemorrhage (IVH) (P =0.046), sepsis (P =0.0001), use of erythropoietin (EPO) (P =0.003), the number of blood transfusions and frequency (P =0.0001 and P =0.0001), surfactant application (P =0.0001), the presence of patent ductus arteriosus (PDA) (P =0.001) or bronchopu- lmonary dysplasia (BPD) (P =0.0001). No significant correlations were found between the occurance of ROP and maternal pre-eclampsia (P =0.293), multiple pregnancy (P = 0.218), or hyperbilirubinemia (P =0.494). Severity of ROP was related significantly with birth weight (P =0.0001), but no significant correlation between severity of ROP and gestational age was present. · CONCLUSION: Early description and reduction of the risk factors related with the occurance of ROP with the help of routine screening programs may warrant the prevention of visual loss, however early ophthalmic diagnosis and treatment are still mandatory to provide better visual rehabilitation. ·

关键词： prematurity retinopathy risk factors gestational age birth weight oxygen therapy

Soluble forms of extracellular cytokeratin 18 may differentiate simple steatosis from nonalcoholic steatohepatitis

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World Journal of Gastroenterology 2007年第6期13卷 837-844页

作者： Yusuf Yilmaz Enver Dolar Engin Ulukaya Semra Akgoz Murat Keskin Murat Kiyici Sibel Aker Arzu Yilmaztepe Selim Gurel Macit gulten Selim Giray Nak Uludag University Medical School Department of Internal Medicine Bursa Turkey Uludag University Medical School Department of Gastroenterology Bursa Turkey Uludag University Medical School Department of Biochemistry Bursa Turkey Uludag University Medical School Department of Statistics Bursa Turkey Uludag University Medical School Department of Pathology Bursa Turkey

AIM: To investigate whether serum levels of two soluble forms of extracellular cytokeratin 18 (M30-antigen and M65-antigen) may differentiate nonalcoholic steatohepatitis (NASH) from simple steatosis in patients with nonalcoholic fatty liver disease (NAFLD). METHODS: A total of 83 patients with suspected NAFLD and 49 healthy volunteers were investigated. Patients with suspected NAFLD were classified according to their liver histology into four groups: definitive NASH (n = 45), borderline NASH (n = 24), simple fatty liver (n = 9), and normal tissue (n = 5). Serum levels of caspase-3 generated cytokeratin-18 fragments (M30-antigen) and total cytokeratin-18 (M65-antigen) were determined by ELISA. RESULTS: Levels of M30-antigen and M65-antigen were significantly higher in patients with definitive NASH compared to the other groups. An abnormal value (> 121.60 IU/L) of M30-antigen yielded a 60.0% sensitivity and a 97.4% specificity for the diagnosis of NASH. Sensitivity and specificity of an abnormal M65-antigen level (> 243.82 IU/L) for the diagnosis of NASH were 68.9% and 81.6%, respectively. Among patients with NAFLD, M30-antigen and M65-antigen levels distinguished between advanced fibrosis and early-stage fibrosis with a sensitivity of 64.7% and 70.6%, and a specificity of 77.3% and 71.2%, respectively. CONCLUSION: Serum levels of M30-antigen and M65-antigen may be of clinical usefulness to identify patients with NASH. Further studies are mandatory to better assess the role of these apoptonecrotic biomarkers in NAFLD pathophysiology.

关键词： Steatosis Steatohepatitis Cytokeratin 18 M30-antigen M65-antigen

Evaluation of leukocyte esterase and nitrite strip tests to detect spontaneous bacterial peritonitis in cirrhotic patients

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World Journal of Gastroenterology 2007年第45期13卷 6027-6030页

作者： Serkan Torun Enver Dolar Yusuf Yilmaz Murat Keskin Murat Kiyici Melda Sinirtas Emre Sarandol Selim Gurel Selim Giray Nak Macit gulten Uludag University Medical School Department of Internal Medicine Bursa 16059 Turkey Uludag University Medical School Department of Gastroenterology Bursa 16059 Turkey Uludag University Medical School Department of Microbiology and Infectious Diseases Bursa 16059 Turkey Uludag University Medical School Departmentof Biochemistry Bursa 16059 Turkey

AIM： To investigate the diagnostic efficacy of leukocyte esterase and nitrite reagent strips for bedside diagnosis of spontaneous bacterial peritonitis （SBP）. METHODS： A total of 63 consecutive patients with cirrhotic ascites （38 male, 25 female） tested between April 2005 and July 2006 were included in the study. Bedside reagent strip testing was performed on ascitic fluid and the results compared to manual cell counting and ascitic fluid culture. SBP was defined as having a polymorphonuclear ascites count of ≥ 250/mm^3. RESULTS： Fifteen samples showed SBP. The sensitivity, specificity, positive and negative predictive values of the leukocyte esterase reagent strips were; 93%, 100%, 100%, and 98%, respectively. The sensitivity, specificity, positive and negative predictive value of the nitrite reagent strips were 13%, 93%, 40%, and 77%, respectively. The combination of leukocyte esterase and nitrite reagents strips did not yield statistically significant effects on diagnostic accuracy. CONCLUSION： Leukocyte esterase reagent strips may provide a rapid, bedside diagnostic test for SBP.

关键词： Spontaneous bacterial peritonitis Urinaryreagent strip Leukocyte esterase Nitrite