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Mangafodipir trisodium-enhanced magnetic resonance imaging for evaluation of pancreatic mass and mass-like lesions

World Journal of Gastroenterology 2006年第10期12卷 1603-1606页

作者： gul eser Aydin Karabacakoglu Serdar Karakose Cengiz eser Ertugrul Kayacetin Department of Radiology Selcuk University Meram Medical Faculty KonyaTurkey Department of Internal Medicine Numune Hospital KonyaTurkey Department of Gastroenterology Selcuk University Meram Medical Faculty KonyaTurkey Co-first-authors:Gul Eser

AIM： To investigate the role of mangafodipir trisodium （MnDPDP） in focal pancreatic masses and mass-like lesions by evaluating contrast uptake features of the lesions and pancreatic parenchyma after contrast medium injection. METHODS： A total of 37 patients with pancreatic mass or mass-like lesions were examined by unenhanced and MnDPDP-enhanced magnetic resonance imaging （MRI）. RESULTS： MRI was obtained 20-40 min after infusion of MnDPDP and homogeneous contrast enhancement was observed in normal pancreas parenchyma. In patients with atrophic pancreas there was no enhancement in pancreatic parenchyma on MnDPDP-enhanced MRI. In 37 patients with 41 pancreatic masses and mass-like lesions, contrast enhancement was observed at 5 lesions on MnDPDP enhanced MRI. Three of these 5 lesions were focal pancreatitis and the other 2 were adenocarcinoma. No contrast enhancement was determined in 36 pancreatic masses and mass-like lesions in 32 patients. CONCLUSION： MnDPDP contrast-enhanced MRI, especially in cases with no parenchyma atrophy, can distinguish focal pancreatic lesion margins. Information about the function of pancreatic parenchyma can be obtained out of tumor. MnDPDP facilitates staging of pancreatic tumors by detection of metastatic lesions in the liver. In addition, diminished heteregenous uptake of MnDPDP in patients with pancreatitis may be helpful in differential diagnosis.

关键词： MnDPDP Pancreas MRI

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Treatment of Massive Low-Grade Chondrosarcoma of Nasal Septum with Helical Tomotherapy: A Case Report

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2016年第4期5卷 263-269页

作者： Hamit Basaran Timur Koca Sibel Karaca Ozlem eser K&iota l&iota nc Fikriye gul Karauc Okan Ö zdemir Ozan Kuduban Arzu Tatar Sare Ş ipal Department of Radiation Oncology Regional Training and Research Hospital Erzurum Turkey Department of Otorhinolaryngology Regional Training and Research Hospital Erzurum Turkey Department of Otorhinolaryngology Ataturk University Faculty of Medicine Erzurum Turkey Department of Pathology Ataturk University Faculty of Medicine Erzurum Turkey

Chondrosarcomas are malignant bone tumors which develop as a cartilaginous differentiation of primary mesenchymal cells and the second most frequently seen malignant tumor of the bone after osteosarcoma. These malignancies are slowly growing non-epithelial tumors with unknown etiology and most frequently seen during the 4 decades of life. They are frequently localized on pelvis, ribs and long bones. Nasal septum CSs are very rarely seen malignancies. They originate from septal mucosa or cartilage and it is difficult to make a diagnosis unless they reach a certain size. A few cases of CSs with nasal septum have been reported in the literature. In cases of CSs, surgery is the gold standard treatment modality;however in surgically unresectable cases or close to margins, radiotherapy plays a significant role in primary and adjuvant treatment. Based on the position of the tumor in head and neck and extremely closeness of the tumor to vital organs as optic nerve, chiasm and brain, image guided-intensity modulated radiation therapy (IG-IMRT) becomes very effective and reliable modalities and may be a favorable treatment alternative.

关键词： Chondrosarcoma Image Guided Intensity Modulated Radiation Therapy

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