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Journal of Animal Science and Biotechnology 2017年第3期8卷 701-706页

作者： Tao Ma Kaidong Deng Yan Tu Naifeng Zhang Bingwen Si guishan xu Qiyu Diao Feed Research Institute/Key laboratory of Feed Biotechnology of the Ministry of Agriculture Chinese Academy of Agricultural Sciences College of Animal Science Jinling Institute of Technology College of Animal Science Tarim University

Background： Dorper is an important breed for meat purpose and widely used in the livestock industry of the ***, the protein requirement of Dorper crossbred has not been investigated. The current paper reports the net protein（NP） and metabolizable protein（MP） requirements of Dorper crossbred ram lambs from 20 to 35 kg ***： Thirty-five Dorper × thin-tailed Han crossbred lambs weaned at approximately 50 d of age（20.3 ± 2.15 kg of BW） were used. Seven lambs of 25 kg BW were slaughtered as the baseline animals at the start of the trial. An intermediate group of seven randomly selected lambs fed ad libitum was slaughtered at 28.6 kg BW. The remaining 21 lambs were randomly divided into three levels of dry matter intake： ad libitum or 70% or 40% of ad libitum intake. Those lambs were slaughtered when the lambs fed ad libitum reached 35 kg BW. Total body N and N retention were ***： The daily NP and MP requirements for maintenance were 1.89 and 4.52 g/kg metabolic shrunk BW（SBW0.75）.The partial efficiency of MP utilization for maintenance was 0.42. The NP requirement for growth ranged from 12.1 to 43.5 g/d, for the lambs gaining 100 to 350 g/d, and the partial efficiency of MP utilization for growth was ***： The NP and MP requirements for the maintenance and growth of Dorper crossbred male lambs were lower than the recommendations of American and British nutritional systems.

关键词： Growth Lamb Maintenance Metabolizable protein Net protein

Effects of protein sources for milk replacers on growth performance and serum biochemical indexes of suckling calves

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Animal Nutrition 2015年第4期1卷 349-355页

作者： Kaiwu Huang Yan Tu Bingwen Si guishan xu Jiangpeng Guo Feng Guo Chuntao Yang Qiyu Diao College of Animal Science Tarim University Feed Research Institute Chinese Academy of Agricultural Sciences Beijing Key Laboratory of Dairy Nutrition The Animal Husbandry Station of Beijing

This study investigated the effects of protein sources for milk replacers on growth performance and serum biochemical indexes of suckling calves. Fifty Chinese Holstein bull calves with similar BW and age were randomly allocated to 5 groups(1 control and 4 treatments) of 10 calves in each group. Five types of milk replacers were designed to have the same level of energy and protein. The protein source for milk replacers of the control group was full milk protein(MP). The protein source of milk replacers of the 4 treatment groups was composed of MP and one vegetable protein(VP)(30 and 70% of total protein). The4 types of VP were soybean protein concentrate(SP), hydrolyzed wheat protein(WP), peanut protein concentrate(PP), and rice protein isolate(RP). Results of the experiment showed: 1) there was no significant difference on average daily gain(ADG) and feed:gain ratio(F:G) among the MP, SP and RP groups(P > 0.05), whereas the ADG and F:G of the WP and PP groups were significantly lower compared with the MP group(P 0.05). Thereby the 4 VP milk replacers had no adverse effects on body size of calves; 3) all groups showed no significant difference in the serum contents of urea nitrogen, total protein, albumin, globulin, β-hydroxybutyrate, growth hormone, insulin-like growth factor-1, and the ratio of albumin to globulin(A:G)(P> 0.05). In conclusion, SP or RP(accounts for 70% of the total protein) as calf milk replacers could substitute MP, whereas wheat gluten and PP had a significant adverse effect on growth performance in this experiment.

关键词： Calf Growth performance Milk replacer Milk protein replacement Serum biochemical parameters Vegetable protein

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钢轨打磨车集尘装置结构优化设计

智能建筑与工程机械 2021年第3期3卷 54-56页

作者：徐贵善中国铁建高新装备股份有限公司云南昆明650215

钢轨打磨作为铁路钢轨维护的重要作业方式,作业过程中磨粉有效收集可降低粉尘对作业环境尤其隧道环境污染,降低打钢轨打磨操作过程中粉尘对人体的危害,提高轨道线路维护作业环保性。

关键词：钢轨打磨集尘装置粉尘环保

非蛋白氮代替蛋白饲料在反刍动物日粮中的应用

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中国饲料 2023年第22期 289-295页

作者：王波梁锐萍许贵善刁其玉青岛农业大学草业学院山东青岛266109 北京市昌平区动物疫病预防控制中心北京102200 新疆塔里木大学新疆阿拉尔843300 中国农业科学院饲料研究所/农业农村部饲料生物技术重点实验室北京100081

蛋白质饲料资源短缺是我国畜牧业发展面临的重大困境,阻碍了畜牧业的提质增效发展。反刍动物可利用部分非蛋白氮(NPN)(如尿素、磷酸脲等)作为饲料氮源,降低饲用豆粕等植物蛋白的消耗,从而在一定程度上缓解蛋白质饲料资源短缺的现状,并... 详细信息

蛋白质饲料资源短缺是我国畜牧业发展面临的重大困境,阻碍了畜牧业的提质增效发展。反刍动物可利用部分非蛋白氮(NPN)(如尿素、磷酸脲等)作为饲料氮源,降低饲用豆粕等植物蛋白的消耗,从而在一定程度上缓解蛋白质饲料资源短缺的现状,并有利于降低生产成本。本文主要围绕反刍动物利用NPN的原理、NPN的饲喂效果以及NPN替代豆粕的效益等进行综述,为进一步推动NPN的合理应用及豆粕减量替代提供科学依据。

关键词：非蛋白氮反刍动物尿素磷酸脲缓释尿素

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不同植物源性蛋白质在犊牛日粮中的应用

饲料工业 2015年第13期36卷 19-24页

作者：黄开武许贵善屠焰刁其玉中国农业科学院饲料研究所奶牛营养学北京重点实验室北京100081 塔里木大学动物科学学院新疆阿拉尔843300

文章综述了中国主要的大豆、小麦、花生、大米等植物蛋白的营养和理化特性,从犊牛生理特点出发,讨论了植物蛋白对哺乳期犊牛生长发育及免疫的影响,以及如何通过物理的、化学的、营养平衡的和生物技术的方法调控犊牛对植物蛋白的消化利... 详细信息

文章综述了中国主要的大豆、小麦、花生、大米等植物蛋白的营养和理化特性,从犊牛生理特点出发,讨论了植物蛋白对哺乳期犊牛生长发育及免疫的影响,以及如何通过物理的、化学的、营养平衡的和生物技术的方法调控犊牛对植物蛋白的消化利用效率。

关键词：植物蛋白犊牛早期断奶免疫

枸杞及其提取物的生物学功能和在畜禽生产中的应用

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动物营养学报 2023年第7期35卷 4207-4215页

作者：段平平张立东胡丽红许贵善塔里木大学动物科学与技术学院阿拉尔843300 塔里木畜牧科技兵团重点实验室阿拉尔843300

枸杞属植物在全国分布广泛,资源丰富。研究发现枸杞营养价值高,富含多种活性物质,如枸杞多糖、类胡萝卜素、甜菜碱、酚类、黄酮类物质等,具有抗氧化、抗疲劳、免疫调节、神经保护、降血糖、抗骨质疏松、抗肿瘤等多种生物学活性。本文综... 详细信息

枸杞属植物在全国分布广泛,资源丰富。研究发现枸杞营养价值高,富含多种活性物质,如枸杞多糖、类胡萝卜素、甜菜碱、酚类、黄酮类物质等,具有抗氧化、抗疲劳、免疫调节、神经保护、降血糖、抗骨质疏松、抗肿瘤等多种生物学活性。本文综述了枸杞的营养成分含量、生物活性物质的功能及其在畜禽饲粮中的应用效果,旨在为枸杞资源化开发提供依据和参考。

关键词：枸杞多糖生物学功能应用

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反刍动物甲烷排放测定和营养调控减排方法

饲料工业 2018年第19期39卷 49-55页

作者：王贝许贵善董利锋刁其玉中国农业科学院饲料研究所北京100081 塔里木大学动物科学学院新疆阿拉尔843300

反刍动物瘤胃内甲烷的产生是饲料能量的浪费,同时还增强了温室效应。因此减少反刍动物甲烷排放对保护环境和提高能量利用率均有重要意义。文章对瘤胃甲烷生成机制、排放量测定方法和营养调控进行概述,就如何减少甲烷排放进行了讨论,旨... 详细信息

反刍动物瘤胃内甲烷的产生是饲料能量的浪费,同时还增强了温室效应。因此减少反刍动物甲烷排放对保护环境和提高能量利用率均有重要意义。文章对瘤胃甲烷生成机制、排放量测定方法和营养调控进行概述,就如何减少甲烷排放进行了讨论,旨在为通过日粮营养调控措施来降低甲烷排放提供参考。

关键词：反刍动物甲烷排放机制测定方法营养因素

肉用绵羊生长期甲烷排放特点与预测模型的建立

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中国农业科学 2019年第10期52卷 1797-1806页

作者：周艳董利锋邓凯东许贵善刁其玉中国农业科学院饲料研究所/农业部饲料生物技术重点实验室塔里木大学动物科学学院金陵科技学院动物科学与技术学院

【目的】通过探索生长期肉用绵羊的甲烷（CH;）排放规律,旨在建立相关的CH;预测模型。【方法】采用单因素试验设计,以饲粮NFC/NDF（非纤维性碳水化合物/中性洗涤纤维）为0.78自由采食组的平均日增重作为饲粮NFC/NDF为1.03组和2.17组的... 详细信息

【目的】通过探索生长期肉用绵羊的甲烷（CH;）排放规律,旨在建立相关的CH;预测模型。【方法】采用单因素试验设计,以饲粮NFC/NDF（非纤维性碳水化合物/中性洗涤纤维）为0.78自由采食组的平均日增重作为饲粮NFC/NDF为1.03组和2.17组的限饲标准,在此基础下测定肉用绵羊的生长性能、营养物质消化率和甲烷产量,并分析肉用绵羊不同体重阶段的甲烷产量与饲粮干物质基础下的营养物质含量、营养物质摄入量、可消化营养物质摄入量及营养物质消化率间的回归关系。【结果】预测肉用绵羊生长早期（25—35 kg）CH;产量的最佳一元和多元回归模型分别为:CH;(L·d;)=-26.58×NFC/NDF+92.7（R;=0.772,P <0.001）;CH;(L·d;)=2.71×NDFD-2.45×DMD-0.97 CPD+124.46（R;=0.846,P=0.001）。预测肉用绵羊生长后期（48-55 kg）CH;产量的最佳一元和多元回归模型分别为:CH;（L/d）=-57.00×GE (MJ·kg;)+1076.0（R;=0.581,P=0.002）;CH;/BW;（L/kg0.75）=-0.013×NDF intake （g/d）-0.13×CP intake （g/d）+0.02×DM intake （g/d）+0.84（R;=0.652,P=0.019）。而肉用绵羊生长期整体CH;产量的最佳一元和多元预测模型分别为:CH;（L/d）=-26.94×NFC/NDF+90.71（R;=0.655,P <0.001）;CH;/BW;（L/kg0.75）=0.005×Digestible NDF intake (g·d;)+0.011×Digestible DM intake (g·d;)-0.097×Digestible CP intake (g·d;)-4.78 （R;=0.722,P <0.001）。【结论】建立了肉用绵羊独立生长阶段（25—35 kg、48—55 kg）和整体生长阶段（25—55 kg）的CH;预测模型。研究表明,处于不同体重阶段的肉用绵羊的最佳甲烷预测因子不尽相同,且甲烷产量受饲粮NFC/NDF影响较大。这可为今后评估我国饲养模式下的甲烷产量提供理论依据,也可为肉用绵羊饲粮的合理配制提供技术参考。

关键词：肉用绵羊甲烷估测模型生长性能表观消化率

Selenium deficiency exacerbates ROS/ER stress mediated pyroptosis and ferroptosis induced by bisphenol A in chickens thymus

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Journal of Environmental Sciences 2025年第2期148卷 13-26页

作者： Kun Wang xu Shi Hongjin Lin Tong xu Shiwen xu College of Veterinary Medicine Northeast Agricultural UniversityHarbin 150030China Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment Harbin 150030China

Bisphenol A(BPA)is an industrial pollutant that can cause immune *** acts as an antioxidant,as selenium deficiency often accompanies oxidative stress,resulting in organ *** study is the first to demonstrate that BPA and/or selenium deficiency induce pyroptosis and ferroptosis-mediated thymic injury in chicken and chicken lymphoma cell(MDCC-MSB-1)via oxidative stress-induced endoplasmic reticulum(ER)*** established a broiler chicken model of BPA and/or selenium deficiency exposure and collected thymus samples as research subjects after 42 *** results demonstrated that BPA or selenium deficiency led to a decrease in antioxidant enzyme activities(T-AOC,CAT,and GSH-Px),accumulation of peroxides(H2O2 and MDA),significant upregulation of ER stress-relatedmarkers(GRP78,IER 1,PERK,EIF-2α,ATF4,and CHOP),a significant increase in iron ion levels,significant upregulation of pyroptosis-related gene(NLRP3,ASC,Caspase1,GSDMD,IL-18 and IL-1β),significantly increase ferroptosis-related genes(TFRC,COX2)and downregulate GPX4,HO-1,FTH,*** vitro experiments conducted in MDCC-MSB-1 cells confirmed the results,demonstrating that the addition of antioxidant(NAC),ER stress inhibitor(TUDCA)and pyroptosis inhibitor(Vx765)alleviated oxidative stress,endoplasmic reticulum stress,pyroptosis,and ***,this study concludes that the combined effects of oxidative stress and ER stress mediate pyroptosis and ferroptosis in chicken thymus induced by BPA exposure and selenium deficiency.

关键词： Bisphenol A Selenium deficiency ROS/ER stress Pyroptosis Ferroptosis Thymic injury

Reducing the measurement errors in nonadiabatic holonomic quantum computers

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Science China(Physics,Mechanics & Astronomy) 2025年第1期68卷 60-66页

作者： Guo-Fu xu Department of Physics Shandong UniversityJinan 250100China

Nonadiabatic holonomic quantum computers serve as the physical platform for nonadiabatic holonomic quantum *** quantum computation has entered the noisy intermediate-scale era,building accurate intermediate-scale nonadiabatic holo-nomic quantum computers is clearly *** that measurements are the sole means of extracting information,they play an indispensable role in nonadiabatic holonomic quantum ***,developing methods to reduce measurement errors in nonadiabatic holonomic quantum computers is of great ***,while much attention has been given to the research on nonadiabatic holonomic gates,the research on reducing measurement errors in nonadiabatic holonomic quantum computers is severely *** this study,we propose a measurement error reduction method tailored for intermediate-scale nonadiabatic holonomic quantum *** reason we say this is because our method can not only reduce the measurement errors in the computer but also be useful in mitigating errors originating from nonadiabatic holonomic *** these features,our method significantly advances the construction of accurate intermediate-scale nonadiabatic holonomic quantum computers.

关键词： quantum holonomy quantum computation measurement errors