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Usefulness of the CONUT index upon hospital admission as a potential prognostic indicator of COVID-19 health outcomes

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Chinese Medical Journal 2022年第2期135卷 187-193页

作者： Adrian K.Bengelloun guillermo J.Ortega Julio Ancochea Ancor sanz-Garcia Diego A.Rodriguez-Serrano guillermo fernandez-Jimenez Rosa Giron Elena Avalos Joan B.Soriano J.Ignacio de Ulibarri Facultad de Medicina Universidad Autónoma de MadridMadridSpain Unidad de Análisis de Datos Instituto de Investigación Sanitaria del Hospital de la PrincesaMadridSpain Servicios de Neumología Admisión y Documentación ClínicaCuidados Intensivos y Nutrición y DietéticaHospital Universitario de La PrincesaMadridSpain Centro de Investigación en Red de Enfermedades Respiratorias(CIBERES) Instituto de Salud Carlos III(ISCIII)MadridEspañaSpain

Background:In-hospital mortality in patients with coronavirus disease 2019(COVID-19)is *** prognostic indices are needed to identify patients at high-risk of COVID-19 health *** aimed to determine the usefulness of the CONtrolling NUTritional status(CONUT)index as a potential prognostic indicator of mortality in COVID-19 patients upon hospital ***:Our study design is of a retrospective observational study in a large cohort of COVID-19 *** addition to descriptive statistics,a Kaplan-Meier mortality analysis and a Cox regression were performed,as well as receiver operating curve(ROC).Results:From February 5,2020 to January 21,2021,there was a total of 2969 admissions for COVID-19 at our hospital,corresponding to 2844 ***,baseline(within 4 days of admission)CONUT index could be scored for 1627(57.2%)***’age was 67.3±16.5 years and 44.9%were *** CONUT severity distribution was:194(11.9%)normal(0-1);769(47.2%)light(2-4);585(35.9%)moderate(5-8);and 79(4.9%)severe(9-12).Mortality of 30 days after admission was 3.1%in patients with normal risk CONUT,9.0%light,22.7%moderate,and 40.5%in those with severe CONUT(P<0.05).An increased risk of death associated with a greater baseline CONUT stage was sustained in a multivariable Cox regression model(P<0.05).An increasing baseline CONUT stage was associated with a longer duration of admission,a greater requirement for the use of non-invasive and invasive mechanical ventilation,and other clinical outcomes(all P<0.05).The ROC of CONUT for mortality had an area under the curve(AUC)and 95%confidence interval of 0.711(0.676-0746).Conclusion:The CONUT index upon admission is potentially a reliable and independent prognostic indicator of mortality and length of hospitalization in COVID-19 patients.

关键词： Admission Clinical risk CONUT COVID-19 Prognosis Score

Land Use/Cover and Productivity in the Compact Agricultural Areas of Mexico

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Journal of Environmental Protection 2014年第16期5卷 1509-1519页

作者： Jesus Soria-Ruiz Yolanda fernandez-Ordonez guillermo Medina-Garcia Gabriel Diaz-Padilla Geomatics Lab National Institute of Research for Forestry Agricultural and Livestock(INIFAP)ZinacantepecMexico Postgraduate College in Agricultural Sciences(COLPOS)Campus Montecillo TexcocoMexico National Institute of Research for Forestry Agricultural and Livestock(INIFAP) ZacatecasMexico Agromaps-Lab National Institute of Research for Forestry Agricultural and Livestock(INIFAP)VeracruzMexico

This paper presents a method to associate land use/cover with productivity in 16 Agrotech Observatories (AOTs) in Mexico. Compact agricultural areas in Mexico have been identified, which are monitored as to their behavior concerning production and rural productivity in a network of AOTs, which is a compact agricultural area representative of agro-ecological, technological and social conditions in the country. To optimize production and agricultural productivity in compact areas, a multidisciplinary and holistic approach with four lines of activity (agro-ecological, technological, economic, and social), and ten actions are used. The objective of this work was to obtain the land use/cover and productivity of sixteen compact agricultural areas (AOTs) in the Mexican Republic, using panchromatic and multispectral SPOT 5 imagery, in order to provide information to the agricultural sector of the country, and to support decision making contributing to the optimization of production in areas with high actual and potential productivity. As an example, in this paper the land use/cover and productivity “AOT 20 Hidalgo” were described. Currently, it is important to have updated and accurate information to support actions and programs of federal, state and local government for farmers, particularly in compact areas with high agricultural production potential.

关键词： Land Use/Cover Productivity SPOT Images Agrotech Observatories Mexico

OPTIMUM POLYTOPAL VECTOR QUANTIZATION WITH COMPUTED PROGRESSIVE DECODING

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OPTIMUM POLYTOPAL VECTOR QUANTIZATION WITH COMPUTED PROGRESS...

Endoscopic ultrasonography-guided celiac plexus neurolysis in patients with unresectable pancreatic cancer: An update

International Conference on Signal Processing(ICSP’93)

作者： Gabriel Robles-De-La-Torre guillermo fernandez-Anaya U.N.A.M. Facultad de IngenieriaDIBCC.U.c.p.04510 and Universidad IberoamericanaDepto.de SistemasMexico D.F. U.N.A.M. Facultad de IngenieriaDIECC.U.c.p.04510 andDepto.de MatematicasMexico D.F.

＜正＞We present a new technique to design polytopal （euclidean distortion based） Vector Quantization （VQ） systems with reduced encoding complexity and the capability of both optimum encoding and progressive decoding with approximately a half of the memory required in the usual Tree-Structured VQ（TSVQ） technique used for this purpose.

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World Journal of Gastrointestinal Endoscopy 2021年第10期13卷 460-472页

作者： guillermo Pérez-Aguado Diego Martinez-Acitores de la Mata Carlos Marra-López Valenciano Ignacio fernandez-Urien Sainz Department of Gastroenterology Complejo Hospitalario Insular Materno Infantil de Gran CanariaLas Palmas de Gran CanariaLas Palmas 35016Spain Department of Gastroenterology Endoscopy UnitComplejo Hospitalario de Navarra CHNPamplona Navarra 31008Spain Department of Gastroenterology Endoscopy UnitAgencia Sanitaria Costa del SolMálaga 29603Spain

Pancreatic cancer produces disabling abdominal pain,and the pain medical management for pancreatic cancer is often challenging because it mainly relies on the use of narcotics(major opioids).However,opioids often provide suboptimal pain relief,and the use of opioids can lead to patient tolerance and several side effects that considerably reduce the quality of life of pancreatic cancer ***-guided celiac plexus neurolysis(EUS-CPN)is an alternative for pain control in patients with nonsurgical pancreatic cancer;EUS-CPN consists of the injection of alcohol and a local anesthetic into the area of the celiac plexus to achieve chemical ablation of the nerve ***-CPN via the transgastric approach is a safer and more accessible technique than the percutaneous *** have reviewed most of the studies that evaluate the efficacy of EUSCPN and that have compared the different approaches that have been performed by *** efficacy of EUS-CPN varies from 50%to 94%in the different studies,and EUS-CPN has a pain relief duration of 4–8 *** factors are involved in its efficacy,such as the onset of pain,previous use of chemotherapy,presence of metastatic disease,EUS-CPN technique,type of needle or neurolytic agent used,*** to this review,injection into the ganglia may be the best technique,and a good visualization of the ganglia is the best predictor for a good EUS-CPN response,although more studies are ***,any of the 4 different techniques could be used to perform EUS-CPN effectively with no differences in terms of complications between the techniques,but more studies are *** effect of EUS-CPN on pain improvement,patient survival and patient quality of life should be evaluated in well-designed randomized clinical *** research also needs to be performed to clarify the best time frame in performing a EUS-CPN.

关键词： Pancreatic cancer Endosonography Celiac plexus neurolysis Opioids Echoendoscopy

TML:a language to specify aerial robotic missions for the framework Aerostack

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International Journal of Intelligent Computing and Cybernetics 2017年第4期10卷 491-512页

作者： Martin Molina Ramon A.Suarez-fernandez Carlos Sampedro Jose Luis Sanchez-Lopez Pascual Campoy Department of Artificial Intelligence Technical University of Madrid(UPM)MadridSpain Centre for Automation and Robotics Technical University of MadridMadridSpain

Purpose–The purpose of this paper is to describe the specification language TML for adaptive mission plans that the authors designed and implemented for the open-source framework Aerostack for aerial ***/methodology/approach–The TML language combines a task-based hierarchical approach together with a more flexible representation,rule-based reactive planning,to facilitate *** approach includes additional notions that abstract programming *** authors built an interpreter integrated in the software framework *** interpreter was validated with flight experiments for multi-robot missions in dynamic ***–The experiments proved that the TML language is easy to use and expressive enough to formulate adaptive missions in dynamic *** experiments also showed that the TML interpreter is efficient to execute multi-robot aerial missions and reusable for different *** TML interpreter is able to verify the mission plan before its execution,which increases robustness and safety,avoiding the execution of certain plans that are not ***/value–One of the main contributions of this work is the availability of a reliable solution to specify aerial mission plans,integrated in an active open-source project with periodic *** the best knowledge of the authors,there are not solutions similar to this in other active open-source *** additional contributions,TML uses an original combination of representations for adaptive mission plans(*** trees with original abstract notions and rule-based reactive planning)together with the demonstration of its adequacy for aerial robotics.

关键词： Adaptive mission plans Aerial robotic systems Autonomous aerial systems Mission plan specification

Comprehensive Left Ventricular Mechanics Analysis by Speckle Tracking Echocardiography in COVID-19

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World Journal of Cardiovascular Diseases 2021年第2期11卷 113-125页

作者： Francisco J. González-Ruiz Emmanuel A. Lazcano-Díaz Zuilma Y. Vásquez-Ortiz Fernanda Bernal-Ceballos Rodrigo Gopar-Nieto Consuelo Orihuela-Sandoval José P. Hernández-Reyes Edgar García-Cruz Eduardo Bucio-Reta Ángel Ramos-Enríquez Luis A. Cota-Apodaca Luis Efren-Santos Blanca Estela Broca-García Daniel Manzur-Sandoval Efrén Melano-Carranza fernandez de la Reguera guillermo Gustavo Rojas-Velasco Francisco Baranda-Tovar Department of Cardiovascular Critical Care National Institute of Cardiology “Dr. Ignacio Chávez” México City México Department of Echocardiography National Institute of Medical Science and Nutrition “Dr. Salvador Zubirán” México City México PhD Program National University of Mexico (UNAM) México City México Cardiovascular Diseases Department National Institute of Cardiology “Dr. Ignacio Chávez” México City México

Background: Cardiac involvement and the consequences of inflammation induced by SARS-CoV2 infection could have catastrophic long-term consequences. Left ventricular mechanics could identify a specific pattern of myocardial fiber damage in patients infected with COVID-19. To our knowledge there are no publications referring to the global description of ventricular mechanics in patients with COVID-19. Objective: To describe left ventricular mechanics in hospitalized patients with COVID-19. Methods: In this cross-sectional study, we included 40 hospitalized patients with confirmed diagnostic of COVID-19, from April 11, 2020, to September 6, 2020. Demographic and laboratory data, clinical and echocardiographic characteristics were collected, as well as events during hospitalization. Left ventricular deformation was analyzed and reported. Results: Subclinical dysfunction was observed in 82.5% (left ventricular longitudinal strain [LVGLS] -17.05% and global circumferential strain [GCS] -18.6%) of the patients, likewise, the mean twist and apical rotation were preserved, and even increased as part of the compensating mechanism to maintain the ejection fraction. Conclusion: In patients hospitalized with COVID-19, despite having a normal left ventricular ejection fraction, subclinical myocardial damage was found, manifested by a decrease in Global Longitudinal Strain (GLS) and Global Circumferential Strain (GCS). This behavior is similar to that of cardiomyopathies in the early stage of the disease, and given the pathophysiological mechanisms involved in the disease, its long-term consequences should be monitored and evaluated.

关键词： COVID-19 Speckle Tracking Echocardiography Myocarditis Cardiomyopa-thy Cardiac Mechanics Strain Myocardial Damage Deformation Imaging Myocardial Strain

Foliar Analysis as an Estimate on the Nutritional State of Conilon Coffee Plantations on Cambisoils

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Journal of Life Sciences 2014年第2期8卷 181-187页

作者： Alberto Perez Diaz Emesto Castaneda Hidalgo Salvador Lozano Trejo Carlos Alberto Bustamante Gonzailez Ramon Antonio Rivera Espinosa Geraldo Rodriguez Ortiz Gloria Martha Martin Alonso Cerelino RoblesPerez guillermo Acosta Coutin Alberto fernandez Turro Centro de Estudios de Cafe y Cacao Universidad de Guantanamo Guantanamo 95300 Cuba Instituto Tecnologico del Valle de Oaxaca Ex Hacienda de Nazareno Xoxocotlan 712320 Mexico Instituto de Investigaciones Agroforestales UCTB-Tercer Frente Santiago de Cuba 92700 Cuba Instituto Nacional de Ciencias Agricolas San Jose de las Lajas Mayabeque 32700 Cuba Universidad de Ciencias Pedagogicas "Raul Gomez Garcla " Guantanamo 95100 Cuba

The objective of this paper relies on the establishment of the sampling moment and the nutritional state of the species Conilon coffee (Coffea canephora) cultivated in Cambisoils. The effect of different rates of nitrogen fertilization was also studied in the leaves concentrations of N, at randomized complete block designs (N 0 = 0; N 1 = 50; N 2 = 100; N 3 = 150 and N 4 = 200 kg?ha -1 of N) in presence of P (40 kg?ha -1 of P 2 O 5 ) and K (160 kg?ha -1 of K 2 O), with four replicates. The samples were carried out in the months of March (flower blossoming stage), June (fruits growing stage), September (grain development) and December (maturation) in all treatments. Foliar analysis carried out in the month of June (fruits growing stage) for the purpose of establishing critical nutrient range values for N, settling down approaches of interpretation of the same one for the Conilon coffee plantations on Cambisoils. The biggest percentages in the yields are obtained with leaves containing N between 2.80% and 3.10%, a value below 2.80% N which they associated with indicative percentages of stable maximum yield that did not surpass the limits of the adequate nutrients supply.

关键词：咖啡树种植园营养状况叶面果实生长期评估随机区组设计营养状态