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National trends in sexual intercourse and usage of contraception among Korean adolescents

World Journal of Pediatrics 2024年第9期20卷 935-948页

作者： Jun Hyuk lee Myeongcheol lee Hojae lee Jaeyu Park sunyoung Kim Ai Koyanagi lee smith Min seo Kim guillermo f.lópez sánchez Elena Dragioti Masoud Rahmati Jiseung Kang Hans Oh Dong Keon Yon Center for Digital Health Medical Science Research InstituteKyung Hee University College of MedicineSeoulSouth Korea Health and Human science University of Southern CaliforniaLos AngelesCAUSA Department of Regulatory science Kyung Hee UniversitySeoulSouth Korea Department of family Medicine Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Research and Development Unit Parc Sanitari Sant Joan de DeuBarcelonaSpain Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Cardiovascular Disease Initiative Broad Institute of MIT and HarvardCambridgeMAUSA Division of Preventive Medicine and Public Health Department of Public Health SciencesSchool of MedicineUniversity of MurciaMurciaSpain Pain and Rehabilitation Centre Department of Medical and Health SciencesLinköping UniversityLinköpingSweden Research laboratory Psychology of Patients Department of NursingSchool of Health SciencesFamiliesand Health ProfessionalsUniversity of IoanninaIoanninaGreece Department of Physical Education and sport sciences Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran Department of Physical Education and sport sciences Faculty of Literature and HumanitiesVali-E-Asr University of RafsanjanRafsanjanIran Department of Anesthesia Critical Care and Pain MedicineMassachusetts GeneralHospitalBostonMAUSA Division of sleep Medicine Harvard Medical SchoolBostonMAUSA suzanne Dworak Peck school of social Work University of Southern CaliforniaLos AngelesCAUSA Department of Pediatrics Kyung Hee University College of Medicine23 Kyungheedae-RoDongdaemun-guSeoul02447South Korea Present Address:CERess-Health service Research and Quality of.life Center Aix-Marseille UniversityMarseilleFrance

Background The exact influence of the COVID-19 pandemic on sexual intercourse and usage of contraception remains largely uncharted *** bridge this gap in knowledge,we conducted a comprehensive,cross-sectional examination of.long-term trends in the prevalence of sexual intercourse and usage of contraception among south Korean adolescents from 2006 to *** In our research,we drew upon data encompassing 1,138,799 south Korean adolescents aged 12 to 18 years,derived from the Korean Youth Risk Behavior Web-based survey(KYRBs)over a period spanning from 2006 to *** focused on the prevalence of sexual intercourse,contraception utilization,and the underlying associated factors among this *** KYRBs data was collected using a complex sampling strategy to determine the national prevalence estimates and shifts in prevalence before(2006-2019)and during(2020-2022)the COVID-19 pandemic *** During the pre-pandemic period,a decrease in adolescent sexual intercourse was observed(6.34%in 2006,5.53%in 2012,and 5.87%in 2019).However,in the post-pandemic period(2020-2022),there was a surge in sexual intercourse(4.55%in 2020 and 6.20%in 2022).This evident alteration in sexual intercourse trajectory between pre-and post-pandemic periods was statistically significant[βdiff,0.950;95%confidence interval(CI),0.756-1.144].Regarding contraceptive use among south Korean adolescents,there was an increase in the pre-COVID-19 pandemic phase across all demographic segments(14.61%in 2006,22.30%in 2012,and 47.69%in 2022)but a notable decline when compared with the pre-and post-pandemic periods(βdiff,-0.319;95%CI,-0.454 to-0.184).Additionally,during the study period,a decrease in sexual intercourse was observed in the pre-pandemic period(β,-0.129;95%CI,-0.148 to-0.110),f.llowed by an increase in the post-pandemic period(β,0.821;95%CI,0.627 to 1.014).This shift is highlighted by an effect size of 0.96[weighted odds ratio(wOR);95%CI,0.92 to 1.00],indicating a subst

关键词： Adolescent Contraception COVID-19 Pandemic Risky sexual behavior

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Handgrip strength and health outcomes: Umbrella review of systematic reviews with meta-analyses of observational studies

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Journal of sport and Health science 2021年第3期10卷 290-295页

作者： Pinar soysal Christopher Hurst Jacopo Demurtas Joseph firth Reuben Howden lin Yang Mark A.Tully Ai Koyanagi Petre Cristian Ilie guillermo f.lopez-sanchez lukas schwingshackl Nicola Veronese lee smith Department of Geriatric Medicine Bezmialem Vakif UniversityIstanbul 34093Turkey Institute of Neuroscience Newcastle UniversityNewcastle upon Tyne NE17RUUK Primary Care Department Azienda Usl Toscana Sud EstGrosseto 52100Italy Division of Psychology and Mental Health University of ManchesterManchester M139PLUK College of Health&Human services University of North Carolina at CharlotteLong BeachCA 90815USA Department of Cancer Epidemiology and Prevention Research Alberta Health ServicesHoly Cross CentreAlbertaT5J 3E4Canada school of Health sciences Institute of Mental Health SciencesUlster UniversityNewtownabbey BT151EDUK Research and Development Unit Sant Joan de Deu Health ParkCIBER of Mental Health(CIBERSAM)Barcelona 08003Spain ICREA Pg.Lluis Companys 23Barcelona 08010Spain The Queen Elizabeth Hospital King’s lynn NHs foundation Trust King’s Lynn PE304ETUK faculty of sport sciences University of MurciaMurcia 30100Spain Institute for Evidence in Medicine Medical CenterUniversity of FreiburgFaculty of MedicineUniversity of FreiburgFreiburg 79085Germany Neuroscience Institute Aging BranchNational Research CouncilPadua 35122Italy The Cambridge Centre for sport and Exercise sciences Anglia Ruskin UniversityCambridge CB11PTUK

Purpose:The aim of the present study was to assess both the credibility and strength of evidence arising from systematic reviews with meta-analyses of observational studies on handgrip strength and health ***:An umbrella review of systematic reviews with meta-analyses of observational studies was *** assessed meta-analyses of observational studies based on random-effect summary effect sizes and their p values,95%prediction intervals,heterogeneity,small-study effects,and excess *** graded the evidence from convincing(Class I)to weak(Class IV).Results:from 504 articles returned in a search of the literature,8 systematic reviews were included in our review,with a total of 11 ***,nine of the 11 of the outcomes reported nominally significant summary results(pssociations surviving the application of the more stringent p value(psented convincing *** associations showed Class II evidence(i.e.,highly suggestive):(1)higher handgrip values at baseline were associated with a minor reduction in mortality risk in the general population(n=34 studies;sample size=1,855,817;relative risk=0.72,95%confidence interval(95%CI):0.670.78),(2)cardiovascular death risk in mixed populations(n=15 studies;relative risk=0.84,95%CI:0.780.91),and(3)incidence of disability(n=7 studies;relative risk=0.76,95%CI:0.660.87).Conclusion:The present results show that handgrip strength is a usef.l indicator for general health status and specifically for early all-cause and cardiovascular mortality,as well as *** further inform intervention strategies,future research is now required to f.lly understand mechanisms linking handgrip strength scores to these health outcomes.

关键词： Handgrip strength Health outcomes Meta-analysis Umbrella review

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The dorsal root ganglion as a target for neurorestoration in neuropathic pain

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Neural Regeneration Research 2024年第2期19卷 296-301页

作者： guillermo Estivill-Torrús Ana Belen Martínez-Padilla lourdes sánchez-salido Anne Baron-Van Evercooren Beatriz García-Díaz Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina(IBIMA Plataforma BIONAND) MálagaSpain Unidad Clínica de Neurociencias Hospital Regional Universitario de MálagaMálagaSpain Departamento de Biología Molecular y Bioquímica Universidad de MálagaSpain sorbonne Université Institut du Cerveau-Paris Brain Institute-ICMINSERMCNRSAP-HPHôpital Pitié-SalpêtrièreParisFrance

Neuropathic pain is a severe and chronic condition widely found in the general *** reason for this is the extensive variety of damage or diseases that can spark this unpleasant constant feeling in *** the processing of pain,the dorsal root ganglia constitute an important region where dorsal root ganglion neurons play a crucial role in the transmission and propagation of sensory electrical ***,the dorsal root ganglia have recently exhibited a regenerative capacity that should not be neglected in the understanding of the development and resolution of neuropathic pain and in the elucidation of innovative ***,we will review the complex interplay between cells(satellite glial cells and inflammatory cells)and factors(cytokines,neurotrophic factors and genetic factors)that takes place within the dorsal root ganglia and accounts for the generation of the aberrant excitation of primary sensory neurons occurring in neuropathic *** importantly,we will summarize an updated view of the current pharmacologic and nonpharmacologic therapies targeting the dorsal root ganglia for the treatment of neuropathic pain.

关键词： cytokines dorsal root ganglia genetic factors neuropathic pain neurotrophic factors pharmacologic and nonpharmacologic therapies satellite glial cells sensory neurons

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Twenty years of population dynamics in European beech-oak forest at their rear range margin anticipate changes in its structure and composition

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forest Ecosystems 2024年第3期11卷 358-370页

作者： álvaro Rubio-Cuadrado Iciar Alberdi Isabel Canellas fernando Montes Jesús Rodríguez-Calcerrada Rosana lópez guillermo G.Gordaliza María Valbuena-Carabana Nikos Nanos Ramón Perea luis Gil Departamento de dinamica y gestion forestal Instituto de Ciencias Forestales(ICIFOR-INIA)CSICCtra.La Coruna km 7.528040MadridSpain Departamento de sistemas y Recursos Naturales Escuela Tecnica Superior de Ingeniería de MontesForestal y del Medio NaturalUniversidad Politecnica de Madrid.Ciudad Universitaria s/n28040MadridSpain school of forestry and Natural Environment Aristotle University of ThessalonikiUniversity Campus54124ThessalonikiGreece

There is an increasing interest in restoring degraded forests,which occupy half of the forest *** the forms of restoration,passive restoration,which involves the elimination of degrading factors and the free evolution of natural dynamics by applying minimal or no management,is gaining *** dynamics is difficult to predict due to the influence of multiple interacting factors such as climatic and edaphic conditions,composition and abundance of species,and the successional character of these ***,we study the natural dynamics of a mixed forest located in central spain,which maintained an open forest structure,due to intensive use,until grazing and cutting were banned in the *** most frequent woody species in this forest are fagus sylvatica,Quercus petraea,Quercus pyrenaica,Ilex aquif.lium,sorbus aucuparia,sorbus aria and Prunus avium,with contrasting shade and drought *** species are common in temperate European deciduous forest and are found here near their southern distribution limit,except for *** order to analyze forest dynamics and composition,three inventories were carried out in 1994,2005 and *** results show that,despite the Mediterranean influence,the natural dynamics of this forest has been mainly determined by different levels of shade *** the abandonment of grazing and cutting,*** expanded rapidly due to its lower shade tolerance,whereas after canopy closure and forest densification,shade-tolerant species gained ground,particularly ***,despite its lower drought and late-frost *** the current dynamics continue,*** will overtake the rest of the species,which will be relegated to sites with shallow soils and steep ***,all the multi-centennial beech trees,which are undergoing a rapid mortality and decline process,will disappear.

关键词： forest succession secondary forest Woodland Mixed forest Competition Recruitment

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Wind power potential over northern south America using ERA5-land global reanalysis

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Clean Energy 2024年第2期8卷 104-112页

作者： Heli A.Arregocés guillermo J.Bonivento Roberto Rojano Grupo de Investigación GIsA Facultad de IngenieríaUniversidad de La GuajiraRiohachaColombia Grupo Procesos fisicoquímicos Aplicados Facultad de IngenieríaUniversidad de Antioquia SIU/UdeACalle 70 No.52-21MedellínColombia

The northernmost region of south America has great potential for wind energy production and is a strategic area for the energy tran*** analysed data from ERA5-land global reanalysis from 1980 to 2020 to determine the wind power potential in this *** aim was to identify areas with a high potential for wind energy that could be used to supply energy in case of drought in the region or increases in fuel *** compared data from 19 meteorological stations located in Colombia with ERA5-land reanalysis data to generate reliable information for the feasibility and operation of wind *** to our analysis,the Colombian Caribbean and Coastal Plain have monthly average wind speeds at 90 m ranging from 4.85 to 10.34 m/s and 3.79 to 6.62 m/s,*** on wind power density calculations,these regions have the highest wind power density in our study,with a monthly average of between 250 and 399 W/m^(2).The Caribbean Region had a 69%increase in wind power density from January to July compared with the annual *** wind power density in the plains increased from January to March,while the Mountain Region had higher anomalies from May to *** Alta Guajira and ParaguanáPeninsula have great potential to generate wind energy due to their privileged geographical *** ERA5 offers valuable information about wind availability in time and space,it cannot represent the influence of.local effects on wind patterns for the Mountain Region.

关键词： onshore wind power wind power potential ERA5-land global reanalysis wind speed

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Increased CO2 levels during the first Half of Incubation at High Altitude Modifies Embryonic Development of fertile leghorn Breeder Eggs

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food and Nutrition sciences 2024年第7期15卷 524-547页

作者： Marco A. Juárez-Estrada Erik I. lópez-Ruiz sonia lópez-Cordova guillermo Tellez-Isaias Omar f. Prado-Rebolledo Departamento de Medicina y Zootecnia de Aves Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Autnoma de Mxico Ciudad de Mxico Mxico Department of Poultry science Division of Agriculture University of Arkansas Fayetteville USA facultad de Medicina Veterinaria y Zootecnia Universidad de Colima Tecomn Mxico

The exchange of oxygen (O2) and carbon dioxide (CO2) within an incubator has a significant impact on embryonic development (ED) and hatching processes. This study examines the influence of non-ventilation (NV) conditions during the first ten days of incubation at high altitudes on leghorn hens hatching eggs. five hundred four hatching eggs were equally divided into three treatment groups and placed in twelve incubators (R = 4). The first group was subjected to standard ventilated conditions (V) during the setting phase. The ventilation inlet holes of the remaining incubators in the NV treatments were closed with either micropore (M) or polypropylene (P) tape, referred to as NVM and NVP groups, respectively. These two different airtight settings were intended to allow for a gradual rise in CO2 naturally generated by the embryos. Results indicate that carbon dioxide concentration gradually increased during the first half of incubation, reaching 1.42% in the NVM group and 1.20% in the NVP group, while the V condition group remained at 0.15%. from 10 days of incubation onwards, normal V conditions were restored in all incubators. The highest hatchability of fertile eggs (HfE) was shown by the NVP group (55.7%), f.llowed by the V (52.6%) and NVM (38.6%) groups. The NVP group showed a greater yolk-free body mass (YfBM) from 10 days of incubation until the hatch basket transfer. NV conditions during the first 10 days of incubation at high altitude produced higher YfBM with gradually decreasing yolk sac mass. In comparison to the NVM and V conditions, the particular NVP condition showed a beneficial impact on the quality of hatched chicks. sustaining NVP condition (1.2% of CO2) throughout the first half of incubation at high altitude generated the optimal environment in the incubator ensuring the best hatchability results. This study highlights how important it is for hatchery managers to recognize the influence of.low O2 and high levels of CO2 on the development trajectori

关键词： Non-Ventilation Hypercapnia Hypoxia Egg Mass loss Hatchability Embryonic Mortality Hatchling Chick Quality

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Global pattern of conodont similarity and faunal constraints during the highstand of the Evae eustatic event(late floian, lower Ordovician)

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Journal of Palaeogeography 2024年第4期13卷 883-905页

作者： Gisella M.Della Costa guillermo l.Albanesi CIGEA Facultad de Ciencias Exactas Físicas y Naturales Universidad Nacional de C ordoba Av.V elez Sarsfield 299

One of the largest Ordovician sea-level rises is the Evae transgression, which occurs in the lower part of the Oepikodus evae Biozone, indicative of a late floian age. specifically, the characteristics associated with the highstand of this event included: a higher proportion of specimens of the index species O. evae than other species, a diversity acme in the evae Biozone, and a reduction of biogeographic barriers that resulted in a high proportion of species with cosmopolitan distribution. In the present contribution, the pattern of species similarity among laurentia, Argentine Precordillera, Baltica, Kazakhstania, south China, and Australia is evaluated with a multiple coefficient analysis including only the sections that recorded the highstand of the Evae transgression. Moreover, the effect of possible terrestrial, latitudinal, physicochemical barriers and palaeogeographic distance on the species distribution is statistically analysed. Our results show a global pattern of conodont species distribution that is highly constrained by the tested palaeoenvironmental *** suggests that contrary to what was expected for a prominent transgression, faunal barriers did not decrease significantly during the Evae drowning peak.

关键词： Evae transgression Oepikodus evae Biozone statistical analyses faunal similarities Palaeoenvironmental barriers

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Hydrochar and synthetic natural gas co-production for a f.ll circular economy implementation via hydrothermal carbonization and methanation:An economic approach

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Journal of Environmental sciences 2024年第6期140卷 69-78页

作者： Judith González-Arias guillermo Torres-sempere Miriam González-Castaño francisco MBaena-Moreno Tomás RReina Inorganic Chemistry Department and Materials sciences Institute University of Seville-CSICSevilleSpain Materials sciences Institute(ICMsE) CSIC-University of SevilleSevilleSpain Department of Chemistry and Chemical Engineering Chalmers University of TechnologyGothenburgSE 41296Sweden

Herein we study the economic performance of hydrochar and synthetic natural gas coproduction from olive tree *** process entails a combination of hydrothermal carbonization and *** a previous work,we evidenced that standalone hydrochar production via HTC results ***,we propose a step forward on the process design by implementing a methanation,adding value to the gas ef.luent in an attempt to boost the overall process techno-economic *** different plant capacities were analyzed(312.5,625 and 1250 kg/hr).The baseline scenarios showed that,under the current circumstances,our circular economy strategy in *** analysis of the revenues shows that hydrochar selling price have a high impact on NPV and subsidies for renewable coal production could help to boost the profitability of the *** the contrary,the analysis for natural gas prices reveals that prices 8 times higher than the current ones in spain must be achieved to reach *** seems unlikely even under the presence of a strong subsidy *** costs analysis suggests that a remarkable electricity cost reduction or electricity consumption of the HTC stage could be a potential strategy to reach profitability ***,significant reduction of green hydrogen production costs is deemed instrumental to improve the economic performance of the *** results show the formidable techno-economic challenge that our society faces in the path towards circular economy societies.

关键词： Hydrothermal carbonization CO_(2)waste valorization Methanation Profitability analysis

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Quality evaluation of Nothofagus pumilio seeds linked to forest management and climatic events

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Ecological Processes 2024年第1期13卷 98-107页

作者： Julian Rodríguez-souilla Jimena E.Chaves María Vanessa lencinas Juan Manuel Cellini fidel A.Roig Pablo l.Peri guillermo Martinez Pastur laboratorio de Recursos Agroforestales Centro Austral de Investigaciones Científicas (CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET ) laboratorio de Investigaciones en Maderas (lIMAD) Universidad Nacional de la Plata (UNLP) Instituto Argentino de Nivología Glaciología y Ciencias Ambientales (IAN-IGLA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Instituto Nacional de Tecnología Agropecuaria (INTA) Universidad Nacional de la Patagonia Austral (UNPA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET )

Background forest ecosystems undergo significant transformations due to harvesting and climate fluctuations, emphasizing the critical role of seeding in natural regeneration and long-term structural preservation. Climate change further amplifies these dynamics, affecting phenology across species and regions. In Tierra del fuego(Argentina), Nothofagus pumilio(lenga) forests represent the most important timber resource, and it is managed through different silvicultural strategies. This species demonstrates notable post-disturbance regeneration, yet seed f.ll exhibits signifi-cant variability, leading to variations in seed quality(e.g., viability). This study aims to assess fluctuations in N. pumilio seed quality, determine how it varies concerning forest management strategies, annual productivity, and the co-occurrence of climatic phenomena including El Ni?o-southern Oscillation(ENsO) and the southern Annular Mode(sAM).Results Viable seeds represented 18.4% of the total, notably higher in unharvested than in managed areas. Con-versely, empty seeds were more prevalent in harvested areas(> 75%). seed quality exhibited significant differences across silvicultural treatments, except for insect-predated seeds, which had similar proportions across all areas, though dispersed retention showed higher predation. When considering years with varying production levels, high-production years favoured f.ll and viable seeds, particularly in unharvested forests and aggregated retention, while low-production years saw reduced viability across all treatments. Quadratic models revealed that viability increased with seed production, where unharvested forests achieved the highest values. Climate variability influenced seed proportions, where ENsO+/sAM+ promoting more f.ll and viable seeds, while ENsO–/sAM+ favoured non-predated seeds, especially in unharvested *** seed quality varies among treatments and years with different levels of seeding. Variations in seed qual-ity, l

关键词： forest management seeding Climate change Extreme event Patagonia

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Game changer:How Janus kinase inhibitors are reshaping the landscape of ulcerative colitis mana

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World Journal of Gastroenterology 2024年第35期30卷 3942-3953页

作者： Antonio M Caballero-Mateos guillermo Arturo Cañadas-de la fuente Department of Gastroenterology and Hepatology San Cecilio University HospitalGranada 18014Spain Department of Nursing Faculty of Health SciencesUniversity of GranadaGranada 18004Spain

Recent advancements in the treatment landscape of ulcerative colitis(UC)have ushered in a new era of possibilities,particularly with the introduction of Janus kinase(JAK)-signal transducer and activator of transcription *** novel agents offer a paradigm shift in UC management by targeting key signaling pathways involved in inflammatory *** approved JAK inhibitors(JAKis),such as tofacitinib,f.lgotinib,and upadacitinib,clinicians now have powerf.l tools to modulate immune responses and gene expression,potentially revolutionizing the treatment algorithm for *** trials have demonstrated the efficacy of JAKis in inducing and maintaining remission,presenting viable options for patients who have failed conventional ***-world data support the use of JAKis not only as first-line treatments but also in subsequent lines of therapy,particularly in patients with aggressive disease phenotypes or refractory to biologic *** rapid onset of action and potency of JAKis have broadened the possibilities in the management strategies of UC,offering timely relief for patients with active disease and facilitating personalized treatment *** safety concerns,including cardiovascular risks and infections,ongoing research and post-marketing surveillance will continue to refine our understanding of the risk-benefit prof.le of JAKis in UC management.

关键词： Ulcerative colitis Janus kinase inhibitors f.lgotinib Tofacitinib Upadacitinib

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