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Toluene degradation by a water/silicone oil mixture for the design of two phase partitioning bioreactors

Chinese Journal of Chemical Engineering 2017年第10期25卷 1512-1518页

作者： Maxime guillerm.Annabelle Couvert Abdeltif Amrane Edith Norrant Audrey Breton éric Dumont Erole Nationale Supérieure de Chimie de Rennes UMR CNRS 6226 11 allee de Beaulieu CS 5083K 35708 Rennes Cedex 7 France UCB BioPharma sprl Avenue de l'Industrie B 1420 Braine l'Alleud Belgum Total S.A CSTJF Avenue Larribau CA 374 64018 Pau Cedex France UMR CNRS 6144 GEPEA IMT-Atlantique La Chantrerie 4 rue Alfred Kastler B.P. 20722 44307 Nantes Cedex 3 France

Toluene degradation performances were studied in a 10 L Two-Phase Partitioning Bioreactor(TPPB).The liquid phase consisted of a mixture of water and PDMS 50(Poly Di Methyl Siloxane,*** oil,viscosity of 46 m Pa·s) in the volume ratio of 75%/25%.Two series of experiments were carried out:in the first,the reactor was sequentially supplied with toluene whereas in the second,toluene was continuously *** sludge from the wastewater treatment plant of Beaurade(Rennes,France) was used at an initial concentration of 0.5 dry mass g·(mixture L)^(-1).The elimination capacity(EC) was investigated as well as the change in biomass concentration over *** biodegradation was very ef ficient(removal ef ficiency,RE=100%) for toluene flows ranging from 0.2 to 1.2 ml·h^(-1),corresponding to elimination capacities of up to 104 g·m^(-3)·h^(-1).For a toluene flow of 1.2 ml·h^(-1),the biomass concentration measured at the end of the experiment was 4.7 dry mass g·(mixture L)^(-1).The oxygen concentration in the liquid phase was clearly not a limiting factor in these operating *** on these results,an extrapolation leading to the design of a large-scale pilot TPPB can now be considered to study toluene degradation performances in industrial conditions.

关键词： Degradation Toluene Silicone oil Multiphase reactor Biomass

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Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma

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World Journal of Gastrointestinal Oncology 2021年第10期13卷 1453-1465页

作者： Laurent Quéro Mouna Labidi Marc Bollet Côme Bommier Sophie guillerm.Christophe Hennequin Catherine Thieblemont Department of Radiation Oncology AP-HPSaint Louis HospitalParis 75010France Faculty of Medicine Universitéde ParisParis 75005France Department of Radiation Oncology Hartmann Oncology Radiotherapy GroupLevallois-Perret 92044France Hemato-Oncology DMU DHIAP-HPSaint Louis HospitalParis 75010France

Gastric mucosa-associated lymphoid tissue(MALT)lymphoma is a rare disease which is often associated with Helicobacter pylori(***)***-line treatment of stage IE and IIE localized gastric MALT lymphoma is based on the eradication of *** presence of *** resistance factors such as translocation t(11;18),peri-gastric lymph node involvement and the degree of tumor infiltration of the gastric wall;or lack of response to antibiotic therapy are two main indications to treat with definitive radiotherapy(RT).RT is an effective treatment in localized gastric MALT lymphoma.A moderate dose of 30 Gy allows a high cure rate while being well *** treatment,regular gastric endoscopic follow-up is necessary to detect a potential occurrence of gastric adenocarcinoma.

关键词： Radiotherapy Mucosa-associated lymphoid tissue MALT Helicobacter pylori Lymphoma Review

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Neoadjuvant or adjuvant therapy for gastric cancer

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World Journal of Gastrointestinal Oncology 2015年第8期7卷 102-110页

作者： Laurent Quéro Sophie guillerm.Christophe Hennequin Department of Radiation Oncology Saint Louis Hospital

Currently, there is no international consensus on the best treatment regimen for patients with advanced resectable gastric carcinoma. In the United States, where a limited lymph-node dissection is frequently performed, adjuvant chemoradiotherapy after surgeryis the standard treatment. In Europe, intensified perioperative chemotherapy is commonly administered. In Japan and South Korea, postoperative S-1-based adjuvant chemotherapy after surgery with D2 lymph-node dissection is the standard treatment. Several ongoing trials are currently evaluating the optimal sequence of chemotherapy, radiotherapy, and surgery, as well as the place of targeted therapeutic agents in the treatment of advanced gastric carcinoma.

关键词： Radiotherapy Chemotherapy Review Gastric cancer

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Can soil microbial diversity influence plant metabolites and life history traits of a rhizophagous insect？ A demonstration in oilseed rape

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Insect Science 2017年第6期24卷 1045-1056页

作者： Tom Lachaise Morgane Ourry Lionel Lebreton Anne-Yvonne guillerm.Erckelboudt Juliette Linglin Chrystelle Paty Valerie Chaminade Nathalie Marnet Julie Aubert Denis Poinsot Anne-Marie Cortesero Christophe Mougel IGEPP Agrocampus Ouest INRA Universite de Rennes 1 Le Rheu France IGEPP Agrocampus Ouest INRA Universite de Rennes 1 Universite Bretagne-Loire Rennes France INRA UR1268 BIA-Le Rheu France INRA-AgroParisTech UMR 518 Applied Mathematics and Computer Sciences-Paris France

Interactions between plants and phytophagous insects play an important part in shaping the biochemical composition of plants. Reciprocally plant metabolites can influ- ence major life history traits in these insects and largely contribute to their fitness. Plant rhizospheric microorganisms are an important biotic factor modulating plant metabolites and adaptation to stress. While plant-insects or plant-microorganisms interactions and their consequences on the plant metabolite signature are well-documented, the impact of soil microbial communities on plant defenses against phytophagous insects remains poorly known. In this study, we used oilseed rape （Brassica napus） and the cabbage root fly （Delia radicum） as biological models to tackle this question. Even though D. radicum is a belowground herbivore as a larva, its adult life history traits depend on aboveground signals. We therefore tested whether soil microbial diversity influenced emergence rate and fitness but also fly oviposition behavior, and tried to link possible effects to modifications in leaf and root metabolites. Through a removal-recolonization experiment, 3 soil microbial modalities （＂high,＂＂medium,＂＂low＂） were established and assessed through amplicon sequencing of 16S and 18S ribosomal RNA genes. The ＂medium＂ modality in the rhizosphere significantly improved insect development traits. Plant-microorganism interactions were marginally associated to modulations of root metabolites profiles, which could partly explain these results. We highlighted the potential role of plant-microbial interaction in plant defenses against Delia radicum. Rhizospheric microbial communities must be taken into account when analyzing plant defenses against herbivores, being either below or aboveground.

关键词： Brassica napus Delia radicum life history traits plant primary and secondary metabolites rhizophagous pest soil microbial diversity

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恒定半径的圆弧切片

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木工机床 1986年第4期 39-41页

作者： Fondronnier guillerm.黄崇开

恒定半径的圆弧切片是一种新的切片方法。发展和研究这种方法是为了更好地利用木材,新切片方法的原理是从生产胶合板以来大家所熟悉的圆木平面切片和旋转切片有着紧密的联系。圆弧切片可得到的厚度从十分之几到10mm,甚至还厚些。加工出... 详细信息

恒定半径的圆弧切片是一种新的切片方法。发展和研究这种方法是为了更好地利用木材,新切片方法的原理是从生产胶合板以来大家所熟悉的圆木平面切片和旋转切片有着紧密的联系。圆弧切片可得到的厚度从十分之几到10mm,甚至还厚些。加工出的单板是平滑的,厚度均匀的。这种方法特别适用于小径木加工,因为小径木用这种方法加

关键词：刨切单板厚度木材无机非金属材料旋转切片机圆弧

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