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华法林与胺碘酮联用致抗凝过度引起华法林相关肾病

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药物不良反应杂志 2024年第5期26卷 318-320页

作者：范彩霞郭德群李峥嵘孙桂玲临沂市人民医院药学部临沂276000 临沂市人民医院心血管内科临沂276000

1例49岁男性患者接受主动脉机械瓣置换术后长期口服华法林(5-mg、1次/d),国际标准化比值(INR)维持在1.80~2.50。因房性心动过速联用胺碘酮治疗,1周后出现鼻腔出血,实验室检查示凝血酶原时间(PT)79.7-s,INR 10.17,血清肌酐(Scr)1-032-μm... 详细信息

1例49岁男性患者接受主动脉机械瓣置换术后长期口服华法林(5-mg、1次/d),国际标准化比值(INR)维持在1.80~2.50。因房性心动过速联用胺碘酮治疗,1周后出现鼻腔出血,实验室检查示凝血酶原时间(PT)79.7-s,INR 10.17,血清肌酐(Scr)1-032-μmol/L,血尿素氮(BUN)29.4-mmol/L;尿常规检查显示尿潜血(+),尿蛋白(±)。考虑为联用胺碘酮增强华法林抗凝作用导致华法林抗凝过度,进而引起华法林相关肾病。停用华法林,给予局部止血和维生素K1、氨甲环酸、百令胶囊、碳酸镧咀嚼片及连续血液透析等治疗。5 d后恢复使用华法林,2周后实验室检查示PT 21.0-s,INR 1.82,Scr 179-μmol/L,BUN 19.0-mmol/L;2个月和6个月后复查肾功能指标均在参考值范围。

关键词：抗凝药华法林急性肾损伤华法林相关肾病胺碘酮药物相互作用

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基于边缘计算的车联网任务卸载策略优化研究

无线通信技术 2024年第3期33卷 1-6页

作者：段耀伟孙桂玲郑博文董亮南开大学电子信息与光学工程学院天津300350

边缘计算通过部署在移动网络边缘,提供计算任务卸载以及边缘计算服务,用于支持对于时延敏感的网络通信场景。但随着场景中车辆终端的不均匀分布,容易造成部分节点负载过重,导致产生过长时延和过多能量消耗。本文针对边缘计算在车联网的... 详细信息

边缘计算通过部署在移动网络边缘,提供计算任务卸载以及边缘计算服务,用于支持对于时延敏感的网络通信场景。但随着场景中车辆终端的不均匀分布,容易造成部分节点负载过重,导致产生过长时延和过多能量消耗。本文针对边缘计算在车联网的应用场景,提出了一种多移动终端、多址边缘节点的计算任务卸载策略优化算法。经实验验证,本文的算法相较于仅依赖信道速率的卸载策略等简单边缘负载卸载策略,系统的任务总耗时显著降低。

关键词：车联网边缘计算凸优化

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胎儿心脏超声在先天性心脏病筛查中的应用价值

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中国实用医刊 2024年第17期51卷 74-77页

作者：翟莉莉刘亚君马文斌孙桂玲开封市妇产医院超声科开封

目的探讨胎儿心脏超声在先天性心脏病(CHD)筛查中的应用价值。方法队列研究。抽取2021年10月至2023年10月于开封市妇产医院就诊的疑似胎儿CHD的38例孕妇, 38例均接受常规三维超声检查和胎儿心脏超声检查, 收集胎心心脏图像进行分析;以... 详细信息

目的探讨胎儿心脏超声在先天性心脏病(CHD)筛查中的应用价值。方法队列研究。抽取2021年10月至2023年10月于开封市妇产医院就诊的疑似胎儿CHD的38例孕妇, 38例均接受常规三维超声检查和胎儿心脏超声检查, 收集胎心心脏图像进行分析;以生产结局或引产结局为金标准, 采用Kappa一致性检验分析常规三维超声检查和胎儿心脏超声检查对CHD诊断的一致性。结果 38例经生产或引产共确诊胎儿CHD 17例, 其中室间隔缺损、肺动脉瓣狭窄伴右室发育不良占比较高。在CHD诊断中, 胎儿心脏超声检查检出率(39.47%, 15/38)高于常规三维超声检查(36.84%, 14/38), P<0.05;胎儿心脏超声检查的敏感度、特异度高于常规三维超声检查(P<0.05);二者与生产或引产的诊断结果一致性较好(Kappa=0.735、0.630, P均<0.05)。在不同类型CHD诊断中, 胎儿心脏超声检查诊断符合率(70.59%)高于常规三维超声(52.94%), P<0.05;且常规三维超声和胎儿心脏超声诊断结果与生产或引产的诊断结果一致性较好(Kappa=0.682、0.746, P均<0.05)。结论胎儿心脏超声检查可重点筛查CHD及其类型, 具有较高的敏感度及特异度。

关键词：胎儿心脏超声先天性心脏病筛查临床价值

Major episodes of horizontal gene transfer drove the evolution of land plants

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Molecular Plant 2022年第5期15卷 857-871页

作者： Jianchao Ma Shuanghua Wang Xiaojing Zhu guiling sun Guanxiao Chang Linhong Li Xiangyang Hu Shouzhou Zhang Yun Zhou Chun-Peng Song Jinling Huang State Key Laboratory of Crop Stress Adaptation and Improvement School of Life SciencesHenan UniversityKaifeng 475004China Key Laboratory for Plant Diversity and Biogeography of East Asia Yunnan Key Laboratory for Fungal Diversity and Green DevelopmentKunming Institute of BotanyChinese Academy of SciencesKunming 650201China Department of Entomology China Agricultural UniversityBeijing 100193China Shanghai Key Laboratory of Bio-Energy Crops School of Life SciencesShanghai UniversityShanghai 200444China Fairy Lake Botanical Garden Shenzhen&Chinese Academy of SciencesShenzhen 518004China Department of Biology East Carolina UniversityGreenvilleNC 27858USA

How horizontal gene transfer(HGT)has contributed to the evolution of animals and plants remains a major *** recent progress,defining the overall scale and pattern of HGT events in land plants has been largely *** this study,we performed systematic analyses for acquired genes in different plant groups and throughout land plant *** found that relatively recent HGT events occurred in char-ophytes and all major land plant groups,but their frequency declined rapidly in seed *** major ep-isodes of HGT events occurred in land plant evolution,corresponding to the early evolution of strepto-phytes and the origin of land plants,***,a vast majority of the genes acquired in the two episodes have been retained in descendant groups,affecting numerous activities and processes of land *** analyzed some of the acquired genes involved in stress responses,ion and metabolite transport,growth and development,and specialized metabolism,and further assessed the cumulative ef-fects of HGT in land plants.

关键词： plant evolution adaptation streptophytes cumulative effect stress response growth and development

Agricultural Traceable and Marketing System Based on iOS-Platform and Wireless Sensor Network

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Journal of Computer and Communications 2017年第6期5卷 45-56页

作者： Haiyuan sun Jianping Zhang guiling sun Yangyang Li College of Electronic Information and Optical Engineering Nankai University Tianjin China School of Electronic Information and Electrical Engineering Shanghai Jiaotong University Shanghai China

With the rapid development of Things of Internet and its related technologies such as Wireless Sensor Network and remote access system development, its application on agricultural and farming domain has become a new research direction. This paper discusses a practical and efficient system by applying mobile software development technologies and ZigBee communication network. To achieve a compact and flexible iOS-based client, this study takes advantage of Model-View-ViewModel pattern as well as Client/Server style. Several encryption technologies such as Message Digest algorithm and Rivest Shamir Adleman algorithm are combined to ensure information security. Compared to the common portable marketing system, the proposed system also provides accurate growth information which is collected by wireless sensor network, and proposes a more flexible design pattern for mobile client hence obtaining a better performance on iOS devices.

关键词： iOS Client Online Agricultural Marketing QR Code MVVM Pattern Wireless Sensor Network

Improvement of Forward-Backward Pursuit Algorithm Based on Weak Selection

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Journal of Computer and Communications 2017年第1期5卷 9-19页

作者： guiling sun Yingying Zhang Jun Jia College of Electronic Information and Optical Engineering Nankai University Tianjin China

Forward-backward pursuit (FBP) algorithm is a novel two-stage greedy approach. However once its forward and backward steps were determined during iteration, it would make computing time increased and affected the reconstruction efficiency. This paper presents a algorithm called forward-backward pursuit algorithm based on weak selection (SWFBP) by introducing threshold strategy into FBP algorithm, and in view of that in the first few iterations, most of the atoms which are selected are right, so this part of atoms are directly incorporated into support set instead of using backward strategy to reduce them. Flexible forward and backward steps accelerate the speed of atom selecting and improve the reconstruction accuracy. We compared SWFBP and FBP algorithm via one-dimensional signal and two-dimensional image reconstruction experiments. The simulation results demonstrate that compared with FBP, SWFBP algorithm has superior performance, including higher PSNR, faster computing speed and lower recovery time.

关键词： Compressed Sensing Reconstruction Algorithm FBP Weak Selection

Design and Implementation of E-Commerce Platform Based on Android

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Journal of Computer and Communications 2018年第8期6卷 92-100页

作者： Jie Shen guiling sun Yangyang Li College of Electronic Information and Optical Engineering Nankai University Tianjin China

This paper introduces the basic functions of the e-commerce system implemented on Android, including user management functions, product search functions, product browsing functions, and product tracking functions, etc. It is necessary to use technologies in Android in order to implement each module function. For example, network communication requires Android’s network request technology and data analysis technology. The display of pictures requires the use of Android controls and cache technology. The traceability of products requires camera scanning technology. And RSA decryption technology and so on. Through the above thread pool technology and the use of caching mechanism, the user experience of UI will be improved and unnecessary network resources consumption will be avoided.

关键词： Android E-Commerce Network Communication Image Display Product Traceability

An IP Format Based Algorithm for ZigBee Routing Protocol Optimization

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Journal of Computer and Communications 2016年第7期4卷 48-54页

作者： guiling sun Yuntian He Zhouzhou Li Zhihong Wang College of Electronic Information and Optical Engineering Nankai University Tianjin China

Learning from the conventional practice of network IP address format, this paper proposed an IP-format-based algorithm for ZigBee energy-balanced routing protocol optimization. The algorithm combines node’s cluster address and node’s network short address into a new address and divides the address’s field as IP-format. So that the address will contain information of the network’s topology and provide decision base for a routing algorithm to optimize the original algorithm selection criteria. Meanwhile, in order to improve the ratio of valid data packets and reduce routing overhead, the new algorithm controls the general direction and the number of hops of the RREQ packets to reduce unwarranted data packet transmission. Finally, the simulation carried out on NS platform demonstrates the algorithm’s superiority on network’s delay jitter, overhead and residual energy.

关键词： Wireless Sensor Networks IP Format Cluster Address Energy Balance

A Lightweight MVC Framework Based on Code Decoupling Principle

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Journal of Computer and Communications 2018年第3期6卷 118-127页

作者： guiling sun Yingjie Wang Mengsha Li Zhenjun Liu College of Electronic Information and Optical Engineering Nankai University Tianjin China

This paper analyzed the problems in the existing framework, and achieved a reasonable framework based on reflection and aspect-oriented programming combined with annotations to map the request parameters, and inversion of the control of the various components. The proposed framework reduced the volume of the application context, and achieved the purpose that dependencies between the various components are controlled by the framework. Based on the problems existing in the known framework, the lightweight MVC framework was implemented and the proposed framework was tested by JMeter test tool. The test results showed that the framework proposed in this paper can respond to requests faster, improve access throughput and enhance application performance and user experience. The framework proposed in this paper combined the functions of MVC and IOC to minimize the volume of external dependencies in the development and greatly improved the efficiency of Web applications development.

关键词： Web Online Framework Code Decoupling MVC Pattern