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Synthesis of New Monoporphyrinate Lanthanide Complexes for Potential Use in Optical Limiting

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Synthesis of New Monoporphyrinate Lanthanide Complexes for P...

中国化学会全国第十三届大环化学暨第五届超分子化学学术讨论会

作者： Shitao Fu guijiang zhou Xunjin Zhu Cheng Ye Wai-Kwok Wong and Zaoying Li ( College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072 Department of Chemistry and Centre for Advanced Luminescence Materials, Hong Kong Baptist University, Kowloon Tong, Hong Kong, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080)

Three monoporphyrinate lanthanide complexes based on 5,10,15,20-tetrakis (p-diphenylaminophenyl)-21H,23H-porphine (H2TDPAPP) were synthesized, and experimental investigations of the nonlinear optical transmittance characteristics at 532 nm show that they are excellent optical limiters with performance comparable or superior to those of the reverse saturable absorption dyes such as fullerene C60 and metal phthalocyanine complexes.

关键词： monoporphyrinate lanthanide complexes synthesis optical limiters

来源： cnki会议评论

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从江航电枢纽工程枢纽布置设计

红水河 2024年第2期43卷 37-43页

作者：黄军黄桂江中国能源建设集团广西电力设计研究院有限公司广西南宁530007

针对从江航电枢纽工程坝址地质条件较差、洪峰流量大、枢纽布置难度大等情况,开展枢纽布置设计研究。笔者详细介绍通航建筑物、泄水建筑物、发电建筑物、挡水建筑物等布置设计情况,阐述了设计难点并提出了相应的优化设计措施。监测结果... 详细信息

针对从江航电枢纽工程坝址地质条件较差、洪峰流量大、枢纽布置难度大等情况,开展枢纽布置设计研究。笔者详细介绍通航建筑物、泄水建筑物、发电建筑物、挡水建筑物等布置设计情况,阐述了设计难点并提出了相应的优化设计措施。监测结果表明,枢纽布置紧凑合理、经济,满足规范要求。

关键词：枢纽布置通航建筑物泄水建筑物发电建筑物挡水建筑物从江航电枢纽工程

2012—2023年梧州市水产品和水体中O1/O139群霍乱弧菌监测结果分析

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热带病与寄生虫学 2024年第1期22卷 23-26,36页

作者：林静梅冼桂江梧州市疾病预防控制中心广西梧州543002

目的了解O1/O139群霍乱弧菌在梧州市水产品和水体中的污染状况,为防控工作提供科学依据。方法2012—2023年每年5—10月,对梧州市各农贸市场和超市的水产品和养殖池水随机采样,并定点采集易受污染的池塘水、江河水。对采集的样本进行霍... 详细信息

目的了解O1/O139群霍乱弧菌在梧州市水产品和水体中的污染状况,为防控工作提供科学依据。方法2012—2023年每年5—10月,对梧州市各农贸市场和超市的水产品和养殖池水随机采样,并定点采集易受污染的池塘水、江河水。对采集的样本进行霍乱弧菌分离培养、生化鉴定、血清学分型和毒力基因检测。结果2012—2023年梧州市共监测水产品和水体4844份,共检出O1/O139群霍乱弧菌53份,总检出率为1.09%。其中水产品监测3020份,检出率为1.42%(43/3020),水体监测1824份,检出率为0.55%(10/1824),水产品和水体检出率差异有统计学意义(χ^(2)=8.056,P<0.05)。不同月份的水产品霍乱弧菌检出率差异有统计学意义(χ^(2)=16.053,P<0.05),其中9月的检出率较高(3.54%,12/339),7月的检出率较低(0.68%,4/588)。不同类型水产品和水体的霍乱弧菌检出率差异均有统计学意义(χ^(2)=82.308、15.752,P均<0.05);水产品中蛙类检出率较高(10.27%,23/224),水体中养殖池水检出率较高(2.43%,7/288)。检出的53株菌株中,O1群小川型22株,O1群稻叶型24株,O139群7株;霍乱毒素(cholera toxin,CT)毒力基因均为阴性。结论梧州市水产品和水体均存在霍乱弧菌污染,应进一步加强监测工作力度,及时掌握霍乱弧菌的污染状况,严防霍乱疫情发生。

关键词：霍乱弧菌水产品水体监测梧州市

环状RNA与动脉粥样硬化性缺血性脑卒中的研究进展

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实用医学杂志 2024年第12期40卷 1755-1761页

作者：潘春玲易雪丽苏丽袁胜山韦贵将右江民族医学院广西百色533000 右江民族医学院附属医院医学检验中心广西百色533000 百色市高发病临床分子诊断与研发重点实验室广西百色533000 广西高校桂西高发病临床分子诊断研究重点实验室广西百色533000 右江民族医学院附属医院神经内科广西百色533000

脑卒中是危害中老年人身体健康和生命的主要疾病之一,且近年来呈年轻化的趋势发展。它具有发病率高、死亡率高、致残率高等特点,动脉粥样硬化是脑卒中防治的主要干预目标。环状RNA(circRNA)在脑血管系统中高度表达,在缺血性卒中和缺血... 详细信息

脑卒中是危害中老年人身体健康和生命的主要疾病之一,且近年来呈年轻化的趋势发展。它具有发病率高、死亡率高、致残率高等特点,动脉粥样硬化是脑卒中防治的主要干预目标。环状RNA(circRNA)在脑血管系统中高度表达,在缺血性卒中和缺血再灌注损伤的发病机制中起着重要的调节作用。本文综述了circRNA在动脉粥样硬化、缺血性脑卒中、缺血再灌注损伤的病理生理过程中与miRNA分子网络的作用机制,为circRNA在动脉粥样硬化性脑卒中的基因诊断和药物治疗中的应用提供理论支持。

关键词：环状RNA 缺血性脑卒中动脉粥样硬化病理生理过程预后生物标志物

MARK4在甲基苯丙胺诱导急性肾损伤中的作用

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中南大学学报（医学版） 2024年第6期49卷 878-889页

作者：汤进胡国铅曾梁赵东升唐贵疆刘建业申丽君中南大学湘雅三医院泌尿外科长沙410013 中南大学湘雅三医院血液净化中心长沙410013

目的:甲基苯丙胺(methamphetamine,METH)是一种非法的精神活性物质,可以损害身体的各个器官,其中泌尿系统是其毒性作用的重要靶标之一。本研究旨在探讨微管亲和调控激酶4(microtubule affinity regulating kinase 4,MARK4)在METH诱导急... 详细信息

目的:甲基苯丙胺(methamphetamine,METH)是一种非法的精神活性物质,可以损害身体的各个器官,其中泌尿系统是其毒性作用的重要靶标之一。本研究旨在探讨微管亲和调控激酶4(microtubule affinity regulating kinase 4,MARK4)在METH诱导急性肾损伤(acute kidney injury,AKI)中的作用。方法:选取10只健康成年雄性C57BL/6小鼠,随机分为对照组和METH组,每组5只。METH组腹腔注射METH(20 mg/kg,每天1次,连续3 d),对照组腹腔注射同等体积的生理盐水。末次注射24 h后处死小鼠,通过血清肌酐、血尿素氮和肾脏HE染色检测AKI模型是否建立成功;蛋白质组学技术筛选METH诱导AKI的肾脏组织与正常肾脏组织之间差异表达的蛋白质,并进行基因本体(gene ontology,GO)分析、京都基因与基因组百科全书(Kyoto Encyclopedia of Genes and Genomes,KEGG)分析和生物信息学分析;蛋白质印迹法验证蛋白质组学数据的准确性,选择目标分子,检测小鼠肾脏中MARK4和cleaved caspase-3表达情况。进一步探讨MARK4在METH诱导AKI中的作用。首先在BUMPT细胞中建立METH毒性模型,筛选出合适的METH处理浓度和时间;使用抑制剂抑制MARK4的表达,检测METH处理后BUMPT细胞的活力以及cleaved caspase-3表达情况。结果:蛋白质组学分析共筛选出差异表达蛋白质17个,其中上调11个,下调6个(均P<0.05)。METH处理后小鼠肾脏中MARK4和cleaved caspase-3的表达水平升高(均P<0.05)。BUMPT细胞的活性随METH处理浓度升高而逐渐降低(均P<0.05),其中4 mmol/L的METH处理后BUMPT细胞活力下降至60%。与对照组相比,MARK4和cleaved caspase-3的表达水平随着METH处理浓度的升高和处理时间的延长而升高(均P<0.05),呈浓度和时间依赖性。抑制MARK4表达可以改善METH引起的BUMPT细胞活性下降情况,降低cleaved caspase-3表达,减少BUMPT细胞的细胞凋亡。结论:MARK4在METH诱导AKI小鼠模型中高表达,MARK4通过调控细胞凋亡来介导METH中毒所致AKI。

关键词：甲基苯丙胺急性肾损伤微管亲和调控激酶4 细胞凋亡

维普期刊数据库博看期刊

Microstructures and Mechanical Properties of the TiC/CM247LC Nickel-Based Composite Fabricated by Selective Laser Melting:Effect of Heat Treatment

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Acta Metallurgica Sinica(English Letters) 2023年第12期36卷 1936-1946页

作者： Yuting Lv Yaojie Liu Zhe Zhang Qiang Zhang Hongyao Yu Rui Wang Guangbao Sun guijiang Wei College of Mechanical and Electronic Engineering Shandong University of Science and TechnologyQingdao 266590China Gaona Aero Material Co. Ltd.Beijing 100094China Beijing Key Laboratory of Advanced High Temperature Materials Central Iron and Steel Research InstituteBeijing 100094China Shanghai Key Laboratory of Advanced High-Temperature Materials and Precision Forming Shanghai Jiao Tong UniversityShanghai 200240China Affiliated Hospital of Youjiang Medical University forNationalities Baise 533000China

In this study,TiC/CM247LC nickel-based composite was successfully prepared by selective laser melting,then was heat treated at a solid solution temperature of 1260℃and different aging temperature of 840℃,870℃,900℃and 930℃*** of aging temperatures on the microstructures and mechanical properties were systematically *** results show that the microstructures of all the heat treated samples are composed ofγmatrix,carbides andγ′***γgrains remain a columnar shape after treatments,but the size ofγ′phase grows up gradually with the increasing aging *** composite treated at an aging temperature of 870℃exhibits the best mechanical properties with the tensile strength of 1073 MPa,yield strength of 1004 MPa and elongation of 7.57%.The plastic deformation and strengthening mechanisms of heat treated composite were systematically investigated.

关键词： Selective laser melting Heat treatment Nickel-based composite Microstructures Mechanical properties

秦祖杰教授运用壮医毒虚致病理论治疗肝脓肿临床经验

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中国中医药现代远程教育 2024年第14期22卷 72-75页

作者：郑玲王成龙蒋桂江马艳秦祖杰广西中医药大学研究生院广西南宁530001 广西国际壮医医院民族医学特色诊疗中心广西南宁530000

肝脓肿为外科急危重症,属中医学“肝痈”范畴,多见于中青年男性。壮医认为该病多由毒虚相因,共同作用而起病,属于“谷道毒浊病”范畴,其治疗以解毒补虚为主。此文系统介绍了广西名中医秦祖杰教授从壮医毒虚致病理论论治肝脓肿的临证经验... 详细信息

肝脓肿为外科急危重症,属中医学“肝痈”范畴,多见于中青年男性。壮医认为该病多由毒虚相因,共同作用而起病,属于“谷道毒浊病”范畴,其治疗以解毒补虚为主。此文系统介绍了广西名中医秦祖杰教授从壮医毒虚致病理论论治肝脓肿的临证经验,旨在探讨以壮医理念为主导的综合策略在肝脓肿治疗中的优势。

关键词：肝痈肝脓肿秦祖杰壮医毒虚致病临证经验

Density functional theory investigation on lattice dynamics,elastic properties and origin of vanished magnetism in Heusler compounds CoMnVZ(Z=Al,Ga)

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Chinese Physics B 2021年第8期30卷 301-311页

作者： guijiang Li Enke Liu Guodong Liu Wenhong Wang Guangheng Wu College of Materials Science and Engineering Nanjing Tech UniversityNanjing 211816China State Key Laboratory for Magnetism Institute of PhysicsChinese Academy of SciencesBeijing 100190China Songshan Lake Materials Laboratory Dongguan 523808China School of Materials Science and Engineering Hebei University of TechnologyTianjin 300130China

The lattice dynamics,elastic properties and the origin of vanished magnetism in equiatomic quaternary Heusler compounds CoMnVZ(Z=Al,Ga)are investigated by first principle calculations in this *** to the similar constituent atoms in CoMnVAl and CoMnVGa compounds,they are both stable in LiMgPdSn-type structure with comparable lattice size,phonon dispersions and electronic ***,we find that CoMnVAl is more structurally stable than ***,the increased covalent bonding component in CoMnVAl enhances its mechanical strength and Vickers hardness,which leads to better comprehensive mechanical properties than those of *** and importantly,structural and chemical compatibilities at the interface make non-magnetic semiconductor CoMnVAl and magnetic topological semimetals Co2MnAl/Ga more suitable to be grown in *** to atomic preferential occupation in CoMnVAl/Ga,the localized atoms Mn occupy C(0.5,0.5,0.5)Wyckoff site rather than B(0.25,0.25,0.25)and D(0.75,0.75,0.75)Wyckoff sites in LiMgPdSn-type structure,which results in symmetric band filling and consequently drives them to be ***,by tuning localized atoms Mn to occupy B(0.25,0.25,0.25)or/and D(0.75,0.75,0.75)Wyckoff sites in off-stoichiometric Co-Mn-V-Al/Ga compounds and keeping the total valence electrons as 24,newly compensated ferrimagnetic compounds are theoretically *** hope that our work will provide more choices for spintronic applications.

关键词： Heusler compounds CoMnVAl/Ga first principles calculations lattice dynamics elastic properties nonmagnetic semiconductor

Using machine learning to improve the accuracy of genomic prediction of reproduction traits in pigs

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Journal of Animal Science and Biotechnology 2022年第5期13卷 1293-1304页

作者： Xue Wang Shaolei Shi guijiang Wang Wenxue Luo Xia Wei Ao Qiu Fei Luo Xiangdong Ding Key Laboratory of Animal Genetics and Breeding of Ministry of Agriculture and Rural Affairs National Engineering Laboratory of Animal BreedingCollege of Animal Science and TechnologyChina Agricultural UniversityBeijingChina Hebei Province Animal Husbandry and Improved Breeds Work Station ShijiazhuangHebeiChina Zhangjiakou Dahao Heshan New Agricultural Development Co. LtdZhangjiakouHebeiChina

Background:Recently,machine learning(ML)has become attractive in genomic prediction,but its superiority in genomic prediction over conventional(ss)GBLUP methods and the choice of optimal ML methods need to be ***:In this study,2566 Chinese Yorkshire pigs with reproduction trait records were genotyped with the GenoBaits Porcine SNP 50 K and PorcineSNP50 *** ML methods,including support vector regression(SVR),kernel ridge regression(KRR),random forest(RF)and Adaboost.R2 were *** 20 replicates of fivefold cross-validation(CV)and one prediction for younger individuals,the utility of ML methods in genomic prediction was *** CV,compared with genomic BLUP(GBLUP),single-step GBLUP(ssGBLUP)and the Bayesian method BayesHE,ML methods significantly outperformed these conventional *** methods improved the genomic prediction accuracy of GBLUP,ssGBLUP,and BayesHE by 19.3%,15.0% and 20.8%,*** addition,ML methods yielded smaller mean squared error(MSE)and mean absolute error(MAE)in all *** yielded an improvement of 3.8% on average in accuracy compared to that of GBLUP,and the accuracy of BayesHE was close to that of *** genomic prediction of younger individuals,RF and Adaboost.R2_KRR performed better than GBLUP and BayesHE,while ssGBLUP performed comparably with RF,and ssGBLUP yielded slightly higher accuracy and lower MSE than Adaboost.R2_KRR in the prediction of total number of piglets born,while for number of piglets born alive,Adaboost.R2_KRR performed significantly better than *** ML methods,Adaboost.R2_KRR consistently performed well in our *** findings also demonstrated that optimal hyperparameters are useful for ML *** tuning hyperparameters in CV and in predicting genomic outcomes of younger individuals,the average improvement was 14.3% and 21.8% over those using default hyperparameters,***:Our findings demonstrated that ML methods had better

关键词： Genomic prediction Machine learning Pig Prediction accuracy