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Journal of Materiomics 2024年第1期10卷 145-153页

作者： Bi Hui Zhang Diming Xu Rui Ze Guo Lu Liu xiao Qiang Liu xiang Ming Chen Laboratory of Dielectric Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou310058China Key Laboratory of Multifunctional Materials and Structures Ministry of EducationSchool of Electronic Science and EngineeringXi'an Jiaotong UniversityXi'an710049China

Hybrid improper ferroelectricity has been extensively reported through theoretical prediction and experimental investigation in the oxides with Ruddlesden-Popper(R-P)***,the experimentally reported ferroelectric materials based on triple-layer R-P structures are rare,and the weak ferroelectricity impedes its practical *** the present work,the single-phase Li_(2)Nd_(2)Ti_(3)O_(10)ceramics with A-site cation ordered triple-layer R-P structure was obtained by spark plasma sintering technique,and the crystal structure of P2_(1)ab symmetry was revealed by neutron powder diffraction and transmission electron microscope ***,the switchable ferroelectricity in Li_(2)Nd_(2)Ti_(3)O_(10)ceramics has been observed at room temperature,and the saturated polarization-electric field hysteresis loop was obtained with P_(r)=0.4μC/cm^(2)under the electric field of 250 kV/*** phase transition behavior of Li_(2)Nd_(2)Ti_(3)O_(10)oxides was revealed by the temperature-dependence Raman and dielectric spectra combined with the piezoelectric property.

关键词： Hybrid improper ferroelectricity A-site ordered Ruddlesden-Popper structure Phase transition behavior

Genetic Variations and Nonalcoholic Fatty Liver Disease:Field Synopsis,Systematic Meta-Analysis,and Epidemiological Evidence

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Biomedical and Environmental Sciences 2024年第7期37卷 762-773页

作者： Yamei Li xiang xiao Jie Wang Yixu Liu Xiongfeng Pan Haibin Yu Jiayou Luo Miyang Luo Department of Epidemiology and Health Statistics School of Public HealthUniversity of South ChinaHengyang 421001HunanChina Department of Maternal and Child Health Xiangya School of Public HealthCentral South UniversityChangsha 410008HunanChina Supervision and Inspection Department of Shanghai Healthcare Security Bureau Shanghai 200003China Department of Epidemiology and Health Statistics Xiangya School of Public HealthCentral South UniversityChangsha 410008HunanChina

Objective To systematically summarize the published literature on the genetic variants associated with nonalcoholic fatty liver disease(NAFLD).Methods Literature from Web of Science,PubMed,and Embase between January 1980 and September 2022 was systematically ***-analyses of the genetic variants were conducted using at least five data *** epidemiologic credibility of the significant associations was graded using the Venice *** Based on literature screening,399 eligible studies were included,comprising 381 candidate gene association,16 genome-wide association,and 2 whole-exome sequencing *** identified 465 genetic variants in 173 genes in candidate gene association studies,and 25 genetic variants in 17 genes were included in the *** meta-analysis identified 11 variants in 10 genes that were significantly associated with NAFLD,with cumulative epidemiological evidence of an association graded as strong for two variants in two genes(HFE,TNF),moderate for four variants in three genes(TM6SF2,GCKR,and ADIPOQ),and weak for five variants in five genes(MBOAT7,PEMT,PNPLA3,LEPR,and MTHFR).Conclusion This study identified six variants in five genes that had moderate to strong evidence of an association with NAFLD,which may help understand the genetic architecture of NAFLD risk.

关键词： Nonalcoholic fatty liver disease Genetic association study Genetic variant Systematic review Meta-analysis

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An Efficient and Fast Area Optimization Approach for Mixed Polarity Reed-Muller Logic Circuits

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Chinese Journal of Electronics 2024年第5期33卷 1165-1180页

作者： Yuhao ZHOU Zhenxue HE Jianhui JIANG xiaojun ZHAO Fan ZHANG Limin xiao xiang WANG School of Software Engineering Tongji University Key Laboratory of Agricultural Big Data of Hebei Province Hebei Agricultural University School of Computer Science and Engineering Beihang University School of Electronic and Information Engineering Beihang University

Area has become one of the main bottlenecks restricting the development of integrated circuits. The area optimization approaches of existing XNOR/OR-based mixed polarity Reed-Muller(MPRM) circuits have poor optimization effect and efficiency. Given that the area optimization of MPRM logic circuits is a combinatorial optimization problem, we propose a whole annealing adaptive bacterial foraging algorithm(WAA-BFA), which includes individual evolution based on Markov chain and Metropolis acceptance criteria, and individual mutation based on adaptive probability. To address the issue of low conversion efficiency in existing polarity conversion approaches, we introduce a fast polarity conversion algorithm(FPCA). Moreover, we present an MPRM circuits area optimization approach that uses the FPCA and WAA-BFA to search for the best polarity corresponding to the minimum circuits area. Experimental results demonstrate that the proposed MPRM circuits area optimization approach is effective and can be used as a promising EDA tool.

关键词： Area optimization Combinatorial optimization problem Fast polarity conversion algorithm Fast polarity conversion algorithm Mixed polarity Reed-Muller Mixed polarity Reed-Muller Bacterial foraging algorithm Bacterial foraging algorithm Mixed polarity Reed-Muller Bacterial foraging algorithm BACTERIAL FORAGING ALGORITHM MINIMIZATION EXTRACTION NETWORK

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Single-cell sequencing technology in diabetic wound healing:New insights into the progenitors-based repair strategies

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World Journal of Stem Cells 2024年第5期16卷 462-466页

作者： Zhen xiang Rui-Peng Cai Yang xiao Yong-Can Huang Shenzhen Engineering Laboratory of Orthopaedic Regenerative Technologies Department of Spine SurgeryPeking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina Department of Breast and Thyroid Surgery Peking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina

Diabetes mellitus(DM),an increasingly prevalent chronic metabolic disease,is characterised by prolonged hyperglycaemia,which leads to long-term health *** much effort has been put into understanding the pathogenesis of diabetic wounds,the underlying mechanisms remain *** advent of single-cell RNA sequencing(scRNAseq)has revolutionised biological research by enabling the identification of novel cell types,the discovery of cellular markers,the analysis of gene expression patterns and the prediction of develop-mental *** powerful tool allows for an in-depth exploration of pathogenesis at the cellular and molecular *** this editorial,we focus on progenitor-based repair strategies for diabetic wound healing as revealed by scRNAseq and highlight the biological behaviour of various healing-related cells and the alteration of signalling pathways in the process of diabetic wound *** could not only deepen our understanding of the complex biology of diabetic wounds but also identify and validate new targets for inter-vention,offering hope for improved patient outcomes in the management of this challenging complication of DM.

关键词： Single-cell sequencing Diabetic wound healing Cell subpopulations Heterogeneity Pathogenesis Progenitor cells

Development and validation of a nomogram model for predicting the risk of pre-hospital delay in patients with acute myocardial infarction

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World Journal of Cardiology 2024年第2期16卷 80-91页

作者： Jiao-Yu Cao Li-xiang Zhang xiao-Juan Zhou Department of Cardiology The First Affiliated Hospital of USTCDivision of Life Science and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina

BACKGROUND Acute myocardial infarction(AMI)is a severe cardiovascular disease caused by the blockage of coronary arteries that leads to ischemic necrosis of the *** medical contact is critical for successful AMI treatment,and delays increase the risk of death for ***-hospital delay time(PDT)is a significant challenge for reducing treatment times,as identifying high-risk patients with AMI remains *** study aims to construct a risk prediction model to identify high-risk patients and develop targeted strategies for effective and prompt care,ultimately reducing PDT and improving treatment *** To construct a nomogram model for forecasting pre-hospital delay(PHD)likelihood in patients with AMI and to assess the precision of the nomogram model in predicting PHD *** A retrospective cohort design was employed to investigate predictive factors for PHD in patients with AMI diagnosed between January 2022 and September *** study included 252 patients,with 180 randomly assigned to the development group and the remaining 72 to the validation group in a 7:3 *** risk factors influencing PHD were identified in the development group,leading to the establishment of a nomogram model for predicting PHD in patients with *** model's predictive performance was evaluated using the receiver operating characteristic curve in both the development and validation *** Independent risk factors for PHD in patients with AMI included living alone,hyperlipidemia,age,diabetes mellitus,and digestive system diseases(P<0.05).A characteristic curve analysis indicated area under the receiver operating characteristic curve values of 0.787(95%confidence interval:0.716–0.858)and 0.770(95%confidence interval:0.660-0.879)in the development and validation groups,respectively,demonstrating the model's good discriminatory *** Hosmer–Lemeshow goodness-of-fit test revealed no statistically significant disparity between the an

关键词： Pre-hospital delay Acute myocardial infarction Risk prediction Nomogram

Correction to:Assembly-level analysis on temperature coefficient of reactivity in a graphite-moderated fuel salt reactor fueled with low-enriched uranium

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Nuclear Science and Techniques 2024年第2期35卷 234-235页

作者： xiao-xiao Li De-Yang Cui Chun-Yan Zou Jian-Hui Wu xiang-Zhou Cai Jin-Gen Chen Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China CAS Innovative Academy in TMSR Energy System Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China

Following publication of the original article,the authors observed that both Fig.5 and Fig.4 depict the same *** 5 was inaccurately referenced and *** correct Fig.5 is copied below:The original article has been updated.

关键词： fuel enriched reactivity

Magnesium-containing pellet regulating blast furnace ferrous burden interaction:softening-melting behavior and mechanism

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Journal of Iron and Steel Research International 2024年第7期31卷 1623-1635页

作者： Li-ming Ma Jian-liang Zhang Yao-zu Wang xiao-yong Ma gui-lin Wang Zhuo Li Hui-qing Jiang Zheng-jian Liu School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China School of Intelligence Science and Technology University of Science and Technology BeijingBeijing 100083China Lingyuan Iron and Steel Group Co. Lingyuan 122500LiaoningChina

MgO participates in all stages of sintering,pelletizing,and blast furnace ironmaking,and synergistically optimizing the distribution of MgO in ferrous burden can effectively enhance the interaction within the ferrous burdens and optimize the softening-melting properties of the mixed ***-containing pellets mixed with low-MgO sinter or mixed with high-MgO sinter in the blast furnace ferrous burden structure have opposite softening-melting performance *** the structure of the ferrous burden is magnesium-containing pellets mixed with low-MgO sinter,the magnesium-containing pellets can enhance the interaction of the ferrous burden in the process of softening-melting,which can optimize the composition of the slag phase and improve the slag *** the structure of the ferrous burden is magnesium-containing pellets mixed with high-MgO sinter,the magnesium-containing pellets weaken the interaction of the ferrous burden in the process of softening-melting,increase the content of the high melting point solid-phase particles in the slag,lead to an increase in the viscosity of the slag and difficult separation of the slag and iron,and decrease the permeability of the charge ***,to ensure good permeability of the mixed burden,the following measures are suggested:optimizing the MgO distribution of the ferrous burden,reducing the MgO content of the sinter to 1.96 wt.%,increasing the MgO content of the pellets to 1.03-1.30 wt.%,controlling the MgO/Al_(2)O_(3) ratio of the mixed burden within 1.15-1.32,narrowing the position of the cohesive zone,and maintaining an S value(permeability index)of approximately 150 kPa℃.

关键词： Ironmaking Ferrous burden Softening-melting property Interaction Permeability Slag

Review of Iron-Based Catalysts for Carbon Dioxide Fischer-Tropsch Synthesis

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Transactions of Tianjin University 2024年第2期30卷 178-197页

作者： Ji-Yue Jia Yu-Ling Shan Yong-xiao Tuo Hao Yan xiang Feng De Chen State Key Laboratory of Heavy Oil Processing China University of PetroleumQingdao 266580China College of Chemical Engineering Qingdao University of Science and TechnologyQingdao 266042China Department of Chemical Engineering Norwegian University of Science and Technology7491 TrondheimNorway

Capturing and utilizing CO_(2)from the production process is the key to solving the excessive CO_(2)emission problem. CO_(2)hydrogenation with green hydrogen to produce olefins is an effective and promising way to utilize CO_(2)and produce valuable chemicals. The olefins can be produced by CO_(2)hydrogenation through two routes, i.e., CO_(2)-FTS (carbon dioxide Fischer- Tropsch synthesis) and MeOH (methanol-mediated), among which CO_(2)-FTS has significant advantages over MeOH in practical applications due to its relatively high CO_(2)conversion and low energy consumption potentials. However, the CO_(2)-FTS faces challenges of difficult CO_(2)activation and low olefins selectivity. Iron-based catalysts are promising for CO_(2)-FTS due to their dual functionality of catalyzing RWGS and CO-FTS reactions. This review summarizes the recent progress on iron-based catalysts for CO_(2)hydrogenation via the FTS route and analyzes the catalyst optimization from the perspectives of additives, active sites, and reaction mechanisms. Furthermore, we also outline principles and challenges for rational design of high-performance CO_(2)-FTS catalysts.

关键词： CO_(2)hydrogenation Olefins CO_(2)-FTS Iron-based catalysts

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Clinical characteristics of patients with early gastric prematurity cancer and analysis of complications by endoscopic resection

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World Journal of Gastrointestinal Oncology 2024年第9期16卷 3898-3904页

作者： Hong Zhao xiang-Yu Shi Li-Li Lv Yan-Zong Lai xiao-xiao Bao Jian-Wen Hu Department of Gastroenterology Dongyang People’s HospitalDongyang 322100Zhejiang ProvinceChina Department of Gastroenterology Yiwu Tianxiang Medical East HospitalYiwu 322100Zhejiang ProvinceChina Department of Pathology Dongyang People’s HospitalDongyang 322100Zhejiang ProvinceChina

BACKGROUND Gastric cancer,a prevalent malignancy,poses a severe threat to the health of residents in *** intervention in early stages can extend patients’*** To analyze clinical characteristics of patients with early gastric cancer and efficacy and risk of complications associated with endoscopic *** This study included 175 patients with early gastric cancer treated at our hospital,with no restrictions on sex or *** data,pathological information,and endoscopic biopsy results were *** clinical characteristics of early gastric cancer were analyzed,and endoscopic resection was *** efficacy and incidence of complications were *** analysis was performed using SPSS 26.0 and GraphPad Prism 8.0 *** A total of 175 patients with early gastric cancer were included,with 75.43%(n=132)males and 24.57%(n=43)females.38.29%(n=67)and 35.43%(n=62)of patients had a history of smoking and alcohol consumption,*** included diabetes(8.57%,n=15),coronary heart disease(10.29%,n=18),and hypertension(43.43%,n=76),which was highly prevalent.A history of abdominal surgery and family history of digestive system cancer accounted for 21.14%and 17.14%,*** most common lesion location was the antral part of the stomach(52.00%,n=91),followed by the gastric angle,body,and *** pathological types were predominantly high-grade intraepithelial neoplasia(28.00%,n=49)and well-differentiated adenocarcinoma(26.86%,n=47),followed by moderately differentiated adenocarcinoma,high-moderately differentiated adenocarcinoma,and moderate-lowly differentiated adenocarcinoma.89.14%of the patients had intestinal metaplasia and 85.14%had *** endoscopic resection,re-examination revealed that 13 patients had cancer cells at the tissue margin,with a positive margin rate of 7.43%.Postoperative complications included no cases of gastrointestinal obstruction,but incisional infec

关键词： Early gastric cancer Clinical characteristics Endoscopic resection Complications

Genomic data and ecological niche modeling reveal an unusually slow rate of molecular evolution in the Cretaceous Eupteleaceae

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Science China(Life Sciences) 2024年第4期67卷 803-816页

作者： Kun-Li xiang Sheng-Dan Wu Lian Lian Wen-Chuang He Dan Peng Huan-Wen Peng xiao-Ni Zhang Hong-Lei Li Jia-Yu Xue Hong-Yan Shan gui-Xia Xu Yang Liu Zhi-Qiang Wu Wei Wang State Key Laboratory of Plant Diversity and Specialty Crops Institute of BotanyChinese Academy of SciencesBeijing 100093China Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyLaboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China China National Botanical Garden Beijing 100093China State Key Laboratory of Grassland Agro-Ecosystems and College of Ecology Lanzhou UniversityLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China College of Landscape Architecture and Life Science/Institute of Special Plants Chongqing University of Arts and SciencesChongqing 402160China College of Horticulture Academy for Advanced Interdisciplinary StudiesNanjing Agricultural UniversityNanjing 210095China Fairylake Botanical Garden Shenzhen&Chinese Academy of SciencesShenzhen 518004China

Living fossils are evidence of long-term sustained ecological ***,whether living fossils have little molecular changes remains poorly known,particularly in ***,we have introduced a novel method that integrates phylogenomic,comparative genomic,and ecological niche modeling analyses to investigate the rate of molecular evolution of Eupteleaceae,a Cretaceous relict angiosperm family endemic to East *** assembled a high-quality chromosome-level nuclear genome,and the chloroplast and mitochondrial genomes of a member of Eupteleaceae(Euptelea pleiosperma).Our results show that Eupteleaceae is most basal in Ranunculales,the earliest-diverging order in eudicots,and shares an ancient whole-genome duplication event with the other *** document that Eupteleaceae has the slowest rate of molecular changes in the observed *** unusually low rate of molecular evolution of Eupteleaceae across all three independent inherited genomes and genes within each of the three genomes is in association with its conserved genome architecture,ancestral woody habit,and conserved niche *** findings reveal the evolution and adaptation of living fossil plants through large-scale environmental change and also provide new insights into early eudicot diversification.

关键词： conservation genomics eudicots evolutionary rates niche conservatism phylogenomics

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