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Pregnancy outcomes and risk factors for low birth weight and preterm delivery among HIV-infected pregnant women in Guangxi, China

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Chinese Medical Journal 2012年第3期125卷 403-409页

作者： Yu Lan Li Wen-ying Chen, Ray Y. Tang zhi-rong Pang Jun gui xiu-zhi Meng xiu-ning Zhang Fu-jie Chinese Ctr Dis Control & Prevent Natl Ctr AIDS STD Control & Prevent Beijing 100050 Peoples R China USCDC Global AIDS Program Beijing Off Beijing 100000 Peoples R China US Embassy US Natl Inst Hlth Natl Inst Allergy & Infect Dis Beijing 100000 Peoples R China Prov Ctr Dis Control & Prevent Outpatient Clin Nanning 530000 Guangxi Peoples R China 4 Infect Dis Hosp Nanning Dept Obstet & Gynecol Nanning 530000 Guangxi Peoples R China Maternal & Child Care Serv Hosp Liuzhou Liuzhou 545001 Guangxi Peoples R China Maternal & Child Care Serv Hosp Hengxian Hengxian 530300 Guangxi Peoples R China Capital Med Univ Beijing Ditan Hosp Beijing 100015 Peoples R China

Background Six provinces in China accounted for 70%-80% of all reported HIV/AIDS cases in the country in 2009 and five provinces accounted for 78% of all reported mother-to-child transmission （MTCT） of HIV cases. Because Guangxi belonged to both groups, the Prevention of Mother-to-Child Transmission （PMTCT） Plus program was established there to understand better low birth weight （LBW） and preterm delivery （PD） birth outcomes and their associated risk factors better. Methods Pregnancy outcomes were examined among HIV-infected pregnant women who enrolled in the PMTCT Plus program from June 2006 to February 2009 in Guangxi, China. Multivariate Logistic regression analysis was used to explore the risk factors associated with LBW （〈2500 g） and PD （gestational age 〈37 weeks）. Results The prevalence of LBW and PD among 194 HIV-positive mothers was 19.6% （38/194） and 9.8% （19/194）, respectively. Multivariate Logistic regression analysis showed that CD4 cell count 〈100 cell/IJI （multivariate-adjusted odds ratio （AOR） 5.52; 95% Cl 1.11-25.55） and CD4 cell count 100-199 cells/IJI （AOR3.40; 95% Cl 1.03-11.25, compared to CD4 cell count 〉350 cells/IJI）, gestational age 〈37 weeks （AOR 4.38; 95% Cl 1.29-14.82, compared to 〉37 weeks）, maternal weight 〈45 kg （AOR 5.64; 95% Cl 1.09-29.07） and maternal weight 45-54 kg （AOR 3.55; 95% CI 1.31-9.60, compared to 〉55 kg） at enrollment, and H IV RNA 〉100 000 copies/ml at enrollment （AOR 4.22; 95% CI 1.24-14.32） and 20 000-99 999 （AOR 2.77; 95% Cl 1.01-7.77, compared to 〈20 000 copies/ml） were associated with a higher risk of LBW. For PD, only maternal injection drug use as the route of HIV transmission （AOR 5.30; 95% Cl 1.33-21.14, compared to those infected with HIV through sexual transmission） was significantly associated with a higher risk of PD. Conclusions Lower CD4 cell count and higher HIV RNA viral load at enrollment were associated with LBW. Optimal antenatal care, including earlier antenatal screening and HIV diagnosis, is critica

关键词： pregnancy outcome low birth weight preterm delivery HIV," pregnant women

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26例先天性心脏病患者术后发热原因分析

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中国感染控制杂志 2016年第5期15卷 309-312,316页

作者：桂秀芝覃婷柳州市妇幼保健院广西柳州545001

目的探讨先天性心脏病患者术后发热原因,提出相应的防控措施。方法选取2013年1—5月某院小儿外科先天性心脏病术后26例患者临床资料进行回顾性分析,并现场观摩手术及术后治疗护理过程,同时对环境进行卫生学监测。结果 26例患者术后均有... 详细信息

目的探讨先天性心脏病患者术后发热原因,提出相应的防控措施。方法选取2013年1—5月某院小儿外科先天性心脏病术后26例患者临床资料进行回顾性分析,并现场观摩手术及术后治疗护理过程,同时对环境进行卫生学监测。结果 26例患者术后均有发热,其中21例患者发热原因为非感染性因素,占80.77%;5例(19.23%)患者为感染性因素(呼吸机相关性肺炎4例,Ⅰ类切口感染1例)。其中吸收热组患者6例,异常发热组患者20例,两组患者年龄、侵入性操作(呼吸机、导尿管、胃管)使用时间比较,差异均有统计学意义(均P<0.05),吸收热组患者年龄较大,侵入性操作时间短。26例患者细菌学送检率为76.92%(20例),共送检标本58份,7份阳性(来自4例患者痰标本),其中铜绿假单胞菌5株(71.43%)。共采集环境标本52份,合格率为80.77%(42份)。结论先天性心脏病术后发热患者,以非感染性因素为主要原因,医护人员应加强无菌观念,规范各项医疗操作,减少术后发热。

关键词：先天性心脏病心脏直视发热非感染性发热

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某妇幼保健院医务人员手卫生依从性调查

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中国消毒学杂志 2016年第10期33卷 997-998,1002页

作者：覃婷桂秀芝广西壮族自治区柳州市妇幼保健院广西柳州545001

目的了解妇幼保健医务人员手卫生执行情况及其影响因素,以加强手卫生管理。方法采用现场查看和考核的方法,对某妇幼保健院医务人员手卫生依从性进行了调查与分析。结果经观察不同岗位医务人员在372个手卫生指征条件下,手卫生总体执行率... 详细信息

目的了解妇幼保健医务人员手卫生执行情况及其影响因素,以加强手卫生管理。方法采用现场查看和考核的方法,对某妇幼保健院医务人员手卫生依从性进行了调查与分析。结果经观察不同岗位医务人员在372个手卫生指征条件下,手卫生总体执行率为36.29%,洗手方法正确率为29.03%。临床护士、医生和实习进修生手卫生执行率依次为41.27%、35.24%和24.00%。在接触体液之后和进行无菌操作之前等重要手卫生指征下,手卫生执行率分别为52.24%和23.86%。结论该医院妇幼保健医务人员手卫生依从性较低,需要加强培训和管理。

关键词：手卫生依从性医务人员调查

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HIV母婴传播及婴儿预防接种

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医学综述 2008年第2期14卷 264-265页

作者：桂秀芝张志勇柳州市妇幼保健院医院感染管理科广西柳州545001 广西医科大学公共卫生学院南宁530021

目前中国艾滋病疫情,女性感染者人数在上升,由此出现人类免疫缺陷病毒(HIV)母婴传播病例,我国HIV母婴传播率为35%左右。临床资料显示,经采取综合性HIV母婴阻断技术后,可使HIV母婴传播的概率下降到8%,在欧美国家甚至可降至2%。作为一种... 详细信息

目前中国艾滋病疫情,女性感染者人数在上升,由此出现人类免疫缺陷病毒(HIV)母婴传播病例,我国HIV母婴传播率为35%左右。临床资料显示,经采取综合性HIV母婴阻断技术后,可使HIV母婴传播的概率下降到8%,在欧美国家甚至可降至2%。作为一种生物制剂,预防接种所使用的疫苗在发挥着巨大的传染病预防功效的同时,也不可避免地会引起一系列生理病理反应。综合各地资料,多数疫苗都曾发生不良反应,其发生率各地不一,以一般反应为主。这是普通婴儿预防接种不良反应的发生情况,对暴露于HIV阳性母亲的婴儿,其预防接种反应如何,有待进一步观察。

关键词：人类免疫缺陷病毒母婴传播预防接种

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Tuning the porosity of {Co12IICo8III（μ3-OH）24（X）}11+ supramolecular frameworks by reaction time for D2/H2 separation

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Science China Chemistry 2025年

作者： Zhuozhou Xie Zhu Zhuo Zi-Ang Nan Qing Li xiufang Li Zi-xiu Lu Linzhe Lü Jin Liu Luyao Liu Wenjing Wang Wei Wang Daqiang Yuan You-gui Huang State Key Laboratory of Structure Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences University of Chinese Academy of Sciences Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth Materials Haixi InstitutesChinese Academy of Sciences State Key Laboratory of Physical Chemistry of Solid Surfaces Department of Chemistry College of Chemistry and Chemical EngineeringXiamen University

Systematicly tuning the porosities of porous materials is crucial for targeted gas mixture separation,yet it remains a longstanding *** a common strategy,altering the phenylene ring count in the organic building units has been exploited to adjust pore apertures in metal organic frameworks （MOFs） and covalent organic frameworks （COFs）,resulting in only a stepwise pore size variation of approximately 2.8?.Unlike MOFs and COFs,the porosities for supramolecular assembly frameworks are highly dependent on the packings of the molecular building units in the *** above strategy cannot be applied to supramolecular assembly frameworks and other strategies are required to adjust pore apertures in supramolecular frameworks,especially to achieve porous materials with the optimal pore size for D2/H2separation （～3?）.Here,we successfully modulate the porosity of supramolecular frameworks of[CoII1+12CoIII8L12（μ3-OH）24（X）]1clusters （L=mono-deprotonated 1-iminoisoindole-3-amine,X=ClO?4or Cl?） by controlling the duration of self-assembly *** simply adjusting the reaction time,we obtain three[CoII12CoIII8L12（μ3-OH）24（X）]11+supramolecular frameworks:[CoII12CoIII8（μ3-OH）24（ClO4）L12)]·（Cl）4·（HCO2）7（1）,[CoII12CoIII8L12（μ3-OH）24（Cl）]·（ClOI4）4·（Cl）6·（HCO2）·（H2O）10（2）,and[CoI12CoIII8L12（μ3-OH）24（Cl）]·（Cl）11·（H2O）12（3）.The different stacking patterns of the[CoII12CoIII8L12（μ3-OH）24（X）]11+clusters in these frameworks lead to significantly varied stabilities and *** 1 exhibits permanent porosity with interconnected channels and maintains stability under harsh *** contrast,compound 2 is nearly nonporous,and compound 3 becomes unstable upon *** pores of compound 1 show higher affinity to D2than H2,and the pore aperture diameter of compound 1 （～3.06?） meets the optimal porosity for D2/***,compound 1 demonstrates moderate D2/H2separation at 77 K (retention time:～7 min/g for D2/H2/Ne （10/10/80 vol%） in a flow of 5 mL

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Cerebral fat embolism following autologous fat injection in facial reconstruction:A case report

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World Journal of Clinical Cases 2025年第2期13卷 50-58页

作者： xiu-Ying Chen Fa Shen Chang Cheng Yu-Han Wang Wen-Chao Cheng De-zhi Yuan Wen Huang Department of Neurology Chongqing Emergency Medical CenterChongqing University Central HospitalChongqing 400000China Department of Neurology Xinqiao HospitalThe Army Medical University(Third Military Medical University)Chongqing 400000China

BACKGROUND Autologous fat injection in facial reconstruction is a common cosmetic *** cerebral fat embolism(CFE)as a complication is rare,it carries serious health *** SUMMARY We present a case of a 29-year-old female patient who developed acute CFE following facial fat filling *** the surgery,the patient experienced symptoms including headache,nausea,vomiting,and difficulty breathing,which was followed by neurological symptoms such as slurred speech and left-sided *** physical examination and auxiliary investigations,including blood tests,head and neck computed tomography angiography,and cranial magnetic resonance diffusion-weighted imaging,were performed upon *** clinical diagnosis was acute cerebral embolism following facial fat filling *** included measures to improve cerebral circulation,dehydration for intracranial pressure reduction,nutritional support,and rehabilitation therapy for left limb *** patient showed a significant improvement in symptoms after 2 weeks of *** recovered left limb muscle strength to grade 5,had clear speech,and experienced complete relief of *** Our case highlights the potential occurrence of severe complications in patients undergoing fat injection in facial *** prevent these complications,plastic surgeons should enhance their professional knowledge and skills.

关键词： Cerebral fat embolism Mechanical thrombectomy Thrombolysis Steroid therapy Symptomatic treatment Case report

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HIV暴露婴儿预防接种免疫效果报告

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中国药物警戒 2010年第10期7卷 588-591页

作者：桂秀芝翁毓秋莫胜邱慧柳州市妇幼保健院广西柳州545001 柳州市疾病预防控制中心广西柳州545001

目的为评估经HIV母婴阻断措施后该类婴儿群对卡介苗、乙肝疫苗的免疫反应能力,为相关部门制定此类婴儿的预防接种政策提供依据。方法为HIV感染孕妇提供综合性母婴阻断措施,将其婴儿设为观察组,母亲HIV阴性婴儿为对照组。对2组婴儿按常... 详细信息

目的为评估经HIV母婴阻断措施后该类婴儿群对卡介苗、乙肝疫苗的免疫反应能力,为相关部门制定此类婴儿的预防接种政策提供依据。方法为HIV感染孕妇提供综合性母婴阻断措施,将其婴儿设为观察组,母亲HIV阴性婴儿为对照组。对2组婴儿按常规进行预防接种,在接种卡介苗3～6个月后作结核菌素(PPD)试验、乙肝疫苗7～10个月后作乙肝抗体(抗-HBs)水平检测。结果 HIV感染孕妇经孕期规范抗病毒治疗后母婴阻断效果明显,其婴儿感染率远低于未治疗者。2组婴儿的PPD阳性率及卡痕阳性率均达90%以上;抗-HBs水平,观察组为296.83±3.10mIU/mL,对照组为354.30±2.37mIU/mL。结论本组资料显示,HIV阳性孕妇经综合性HIV母婴阻断措施后其所娩婴儿对乙肝疫苗和卡介苗具有类似于普通婴儿的免疫反应能力。

关键词： HIV暴露婴儿预防接种免疫效果

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On the Convergence of Products _sh_1h_n in the Adams Spectral Sequence

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Acta Mathematica Sinica,English Series 2007年第6期23卷 1025-1032页

作者： xiu gui LIU School of Mathematical Sciences and LPMC Nankai University Tianjin 300071 P.R. China

Abstract Let A be the mod p Steenrod algebra and S the sphere spectrum localized at p, where p is an odd prime. In 2001 Lin detected a new family in the stable homotopy of spheres which is represented by （b0hn-h1bn-1）∈ ExtA^3,（p^n＋p）q（Zp,Zp） in the Adams spectral sequence. At the same time, he proved that i.（hlhn） ∈ExtA^2,（p^n＋P）q（H^＊M, Zp） is a permanent cycle in the Adams spectral sequence and converges to a nontrivial element ξn∈π（p^n＋p）q-2M. In this paper, with Lin＇s results, we make use of the Adams spectral sequence and the May spectral sequence to detect a new nontrivial family of homotopy elements jj′j^-γsi^-i′ξn in the stable homotopy groups of spheres. The new one is of degree p^nq ＋ sp^2q ＋ spq ＋（s - 2）q ＋ s - 6 and is represented up to a nonzero scalar by hlhnγ-s in the E2^s＋2,＊-term of the Adams spectral sequence, where p ≥ 7, q = 2（p - 1）, n ≥ 4 and 3 ≤ s 〈 p.

关键词： stable homotopy groups of spheres Adams spectral sequence May spectral sequence

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A Nontrivial Product of Filtration s+5 in the Stable Homotopy of Spheres

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Acta Mathematica Sinica,English Series 2007年第3期23卷 385-392页

作者： xiu gui LIU Department of Mathematics and LPMC Nankai University Tianjin 300071 P. R. China

In this paper, some groups Ext A^s.t （Zp, Zp） with specialized s and t are first computed by the May spectrM sequence. Then we make use of the Adams spectral sequence to prove the existence of a new nontrivial family of filtration s＋5 in the stable homotopy groups of spheres πpnq＋（s＋3）pq＋（s＋1）q-5S which is represented （up to a nonzero scalar） by β＋2bohh∈ExtA^s＋5,P^nq＋（n＋3）pq＋（n＋1）q＋s（Zp, Zp） in the Adams spectral sequence, where p ≥ 5 is a prime number, n ≥3, 0≤ s 〈 p - 3, q = 2（p - 1）.

关键词： Stable homotopy of spheres Adams spectral sequence Toda Smith spectrum May spectral sequence

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Static and dynamic studies of adsorption by four macroporous resins to enrich oridonin from Rabdosia rubescens

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Chinese Journal of Chemical Engineering 2021年第4期34卷 151-158页

作者： Ling Meng Xia gui zhi Yun College of Chemical Engineering Nanjing Tech UniversityNanjing 211816China State Key Laboratory of Generic Manufacture Technology of Chinese Traditional Medicine Lunan Pharmaceutical Group Co.Ltd.Linyi 273400China

Oridonin,one of the active ingredients in Rabdosia rubescens(***),has been reported to induce cell apoptosis and cell cycle arrest in many *** extraction methods tend to result in unsatisfied enrichment and poor quality of oridonin present in a given *** paper aims to evaluate the performance and separation characteristics of four different macroporous resins to arrive at the most suitable methodology for the isolation and purification of highquality *** absorption kinetics,thermodynamic and dynamic adsorption were ***20 was selected for further study due to its high adsorption capacity of 32 mgg 1 and desorption ratio with 98.5%.The pseudosecondorder model was considered to be the most suitable for kinetic results,and Langmuir model was chosen to better describe the absorption *** optimum conditions(flow rate of 4 ml min 1,bed depth with 6 cm and initial concentration of 2.15 mg·ml^1),the effective content of oridonin increased from 33.9%to 79.1%in the dry extract with a recovery of 81%and the purity of oridonin improved from 76%to 93%.The results confirm that HP20 provides an efficient method to purify most oridonin from ***.

关键词： Rabdosia rubescens Oridonin Macroporous resin Adsorption Kinetics Thermodynamics

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