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动物学报 2005年第5期51卷 947-951页

作者： Randall HEPBURN Sarah RADLOFF Nikolaus KOENIGER gudrun KOENIGER Salim TINGEK Department of Zoology and Entomology Rhodes University GrahamstownSouth AfricaEastern Bee Research Institute Yunnan Agricultural University Kunming ChinaDepartment of Statistics Rhodes University GrahamstownSouth AfricaInstitut fur Bienenkunde Universitat Frankfurt GermanyInstitut fur Bienenkunde Universitat Frankfurt GermanyAgricultural Research Station TenomSabah Malaysia

本研究从采粉工蜂飞行中能量消耗相关的几个方面入手,分析了蜜蜂属(Apis) 8个物种的花粉采集器官。结果表明,花粉筐表面积、翅膀表面积、体重及胸部动力容量与蜂种个体的体长呈极显著相关,并且它们随蜂种个体的增大而呈对数线性比例增... 详细信息

本研究从采粉工蜂飞行中能量消耗相关的几个方面入手,分析了蜜蜂属(Apis) 8个物种的花粉采集器官。结果表明,花粉筐表面积、翅膀表面积、体重及胸部动力容量与蜂种个体的体长呈极显著相关,并且它们随蜂种个体的增大而呈对数线性比例增加。除意大利蜜蜂(A·mellifera ligustica)以外,花粉团重量与花粉筐和基跗节表面积成线性比例。工蜂负重前后重量的变化与花粉筐和翅膀的表面积不成比例[动物学报51 (5) :947 -951 , 2005]。

关键词：蜜蜂花粉飞行形态

Effects of Resistant Starch on Symptoms,Fecal Markers,and Gut Microbiota in Parkinson’s Disease—The RESISTA-PD Trial

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Genomics, Proteomics & Bioinformatics 2022年第2期20卷 274-287页

作者： Anouck Becker Georges Pierre Schmartz Laura Groger Nadja Grammes Valentina Galata Hannah Philippeit Jacqueline Weiland Nicole Ludwig Eckart Meese Sascha Tierling Jorn Walter Andreas Schwiertz Jorg Spiegel gudrun Wagenpfeil Klaus Faßbender Andreas Keller Marcus M.Unger Department of Neurology Saarland UniversityD-66421 HomburgGermany Chair for Clinical Bioinformatics Saarland UniversityD-66123 SaarbruckenGermany Department of Human Genetics Saarland UniversityD-66421 HomburgGermany Department of Genetics/Epigenetics Saarland UniversityD-66123 SaarbruckenGermany Institute of Microecology D-35745 HerbornGermany Institute of Medical Biometry Epidemiology and Medical InformaticsSaarland UniversityD-66421 HomburgGermany Department of Neurology Stanford UniversityPalo AltoCA 94305USA

The composition of the gut microbiota is linked to multiple diseases,including Parkinson’s disease(PD).Abundance of bacteria producing short-chain fatty acids(SCFAs)and fecal SCFA concentrations are reduced in *** exert various beneficial functions in *** the interventional,monocentric,open-label clinical trial “Effects of Resistant Starch on Bowel Habits,Short Chain Fatty Acids and Gut Microbiota in Parkinson’s Disease”(RESISTA-PD;ID:NCT02784145),we aimed at altering fecal SCFAs by an 8-week prebiotic intervention with resistant starch(RS).We enrolled 87 subjects in three study-arms:32 PD patients received RS(PD+RS),30 control subjects received RS,and 25 PD patients received solely dietary *** performed paired-end 100 bp length metagenomic sequencing of fecal samples using the BGISEQ platform at an average of 9.9 *** was *** the PD+RS group,fecal butyrate concentrations increased significantly,and fecal calprotectin concentrations dropped significantly after 8 weeks of RS ***,we observed a reduction in non-motor symptom load in the PD+RS *** reference-based analysis of metagenomes highlighted stable alpha-diversity and beta-diversity across the three groups,including bacteria producing ***-free analysis suggested punctual,yet pronounced differences in the metagenomic signature in the PD+RS ***-PD highlights that a prebiotic treatment with RS is safe and well-tolerated in *** stable alpha-diversity and beta-diversity alongside altered fecal butyrate and calprotectin concentrations call for long-term studies,also investigating whether RS is able to modify the clinical course of PD.

关键词： Parkinson’s disease Short-chain fatty acid Microbiota Metagenomics Intestinal inflammation

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不同流量条件下水表性能的研究与表征

上海计量测试 2018年第A2期45卷 39-46页

作者： gudrun Wendt 张聪吴湘 Physikalisch-Technische Bundesanstalt(PTB) 无锡市计量测试院

利用光学、非侵入式激光技术的优点,研究了在机械水表前端和内部的不同流量条件对水表计量性能的影响。重点用激光多普勒测速计(LDA)测量的三维速度分布与水表在理想、扰动流型及不同流量下的误差曲线进行了比较。文章给出了具体的技术... 详细信息

利用光学、非侵入式激光技术的优点,研究了在机械水表前端和内部的不同流量条件对水表计量性能的影响。重点用激光多普勒测速计(LDA)测量的三维速度分布与水表在理想、扰动流型及不同流量下的误差曲线进行了比较。文章给出了具体的技术方案以及优化后的LDA数据处理和展示过程。除了通过各种2D和3D图定性描述流态外,还定义了无量纲参数以实现定量描述,目的在于建立一个可以预测水表示值变化的模型。

关键词：机械水表计量性能流量表征激光技术激光多普勒无量纲参数非侵入式

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埃姆河生态系统中的多氯联苯

人类环境杂志 1998年第5期27卷 384-391页

作者： gudrun Bremle Per Larsson 沈英娃瑞典隆德大学

大气沉降是水环境中诸如多氯联苯(PCB)等持久性污染物的来源之一。其他的点源也在水中的PCB负荷中占有一定的含量。在瑞典东南部的埃姆河中,污染了的底泥是PCB的一个来源,发现其中PCB沉积最多的是Jarnsjon湖——一个与埃姆河相通的小湖... 详细信息

大气沉降是水环境中诸如多氯联苯(PCB)等持久性污染物的来源之一。其他的点源也在水中的PCB负荷中占有一定的含量。在瑞典东南部的埃姆河中,污染了的底泥是PCB的一个来源,发现其中PCB沉积最多的是Jarnsjon湖——一个与埃姆河相通的小湖,底泥中含有约400kg的PCB。该湖下游的水和鱼体中PCB浓度高于上游。在1993年和1994年,Jarnsjon湖曾疏浚清理过。挖出的底泥,据估计所含的PCB约占整个湖的95%以上,被倾倒在一个填埋场。在治理完成后,进行了两年的监测,表明湖水中的PCB浓度在下降,并随水和温度呈季节性变化。在水量小和温度高时,PCB浓度最高。无论是PCB的水平还是在这些水平上的差异,都与在上游一个地点所发现的接近。据发现,在大量排水期间,上游的降水是PCB的主要来源,在小量排水的条件下,则以底泥中的解吸作用为主。在治理后近两年的1996年夏季,进行了埃姆河系统中鱼体内PCB浓度的调查研究。该项调查研究重复了治理前的1991年所进行的研究。结果表明,治理后Jarnsjon湖中一年龄鱼体内的PCB浓度已经减半。

关键词：埃姆河生态系统多氯联苯大气沉降污染源

Scoring the collective effects of SNPs: association of minor alleles with complex traits in model organisms

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Science China(Life Sciences) 2014年第9期57卷 876-888页

作者： YUAN DeJian ZHU ZuoBin TAN XiaoHua LIANG Jie ZENG Chen ZHANG JieGen CHEN Jun MA Long DOGAN Ayca BROCKMANN gudrun GOLDMANN Oliver MEDINA Eva RICE Amanda D. MOYER Richard W. MAN Xian YI Ke LI YanKe LU Qing HUANG YiMin HUANG Shi State Key Laboratory of Medical Genetics Central South University High Performance Computing Center Modern Educational Technology Center New Campus Central South University Department of Crop and Animal Sciences Faculty of Agriculture and Horticulture Humboldt-Universitt zu BerlinInvalidenstraβe 42Berlin 10115 Germany Infection Immunology Group Helmholtz Centre for Infection Research Inhoffenstrae 7Braunschweig 38124 Germany Department of Molecular Genetics and Microbiology University of Florida

It has long been assumed that most parts of a genome and most genetic variations or SNPs are non-functional with regard to reproductive ***,the collective effects of SNPs have yet to be examined by experimental *** here developed a novel approach to examine the relationship between traits and the total amount of SNPs in panels of genetic reference *** identified the minor alleles(MAs)in each panel and the MA content(MAC)that each inbred strain carried for a set of SNPs with genotypes determined in these *** was nearly linearly linked to quantitative variations in numerous traits in model organisms,including life span,tumor susceptibility,learning and memory,sensitivity to alcohol and anti-psychotic drugs,and two correlated traits poor reproductive fitness and strong *** results suggest that the collective effects of SNPs are functional and do affect reproductive fitness.

关键词： collective effects complex traits minor alleles SNPs recombinant inbred lines minor allele content(MAC)

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《联合国荒漠与荒漠化年》简报

第四纪研究 2006年第6期26卷 I0002-I0002页

作者： Arthur Conacher gudrun Gisladottir

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《联合国荒漠与荒漠化年》简报

第四纪研究 2006年第6期26卷 1030-1030页

作者： Arthur Conacher gudrun Gisladottir

The UN should not confuse deserts with *** are good: they have biodiverse ecosystems and rich human cultures and histories. Deserts are not necessarily desertified. In contrast, desertification is bad: it is associated with degraded ecosystems, soil and water; loss of species; loss of productivity; loss of cultural diversity and ecological knowledge, and marginalisation of people. Marginalisation is associated with poverty and a lack of infrastructure, resources,training and assistance.

关键词：联合国荒漠

Molecular Epidemiology of Nontuberculous Mycobacteria in a German CF Center and Clinical Course of NTM Positive Patients

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Open Journal of Medical Microbiology 2013年第1期3卷 39-47页

作者： Carolin Kroner Barbara Ganster Matthias Kappler Ann-Christin Grimmelt Bernd H.Belohradsky Michael Hogardt gudrun Laniado Michael Meissner Soren Schubert Matthias Griese Paediatric Pneumology Dr.von Hauner Children’s HospitalLudwig-Maximilians-UniversityMunichGermany Institute for Clinical Chemistry Molecular DiagnosticsMedical Microbiology and Hygiene DepartmentLudwigshafen General HospitalLudwigshafenGermany Institute for Medical Microbiology and Infection Control University HospitalJohann-Wolfgang-Goethe-UniversityFrankfurt/MainGermany Max von Pettenkofer Institute of Hygiene and Medical Microbiology Ludwig-Maximilians-UniversityMunichGermany

Goal of this study was to analyse the clinical course of cystic fibrosis (CF) patients with nontuberculous mycobacteria (NTM) in their respiratory secretions and to investigate the molecular epidemiology of the most prevalent NTM species by multilocus sequence analysis (MLSA). The respiratory specimen and the clinical parameters forced expiratory volume in one second (FEV1), body-mass-index (BMI), erythrocyte sedimentation rate (ESR) 1 h and immunoglobulin G (IgG) of 357 CF patients, 0 - 52.4 years, mean FEV1 2009 81.5% pred were analysed between 1998 and 2010. In 13 patients NTM were detected. 12 of 13 patients carried M. abscessus, for one patient the NTM species was not characterized. 4 patients carried a second NTM species (M. avium, M. chelonae (2x), M. intracellulare). 6 patients exhibited a significant decline in FEV1, however changes in BMI, IgG and ESR were discordant. Molecular genotyping of M. abscessus isolates revealed a unique MLSA pattern in 6 patients. 2 patients harboured identical strains, and one patient a closely related strain. Whether the presence of identical strains is attributed to the acquisition of NTM clones from common environmental sources or to patient-to-patient transmission cannot be definitely clarified. Although cross-in- fection of the three patients with identical/closely related strains in the present cohort is highly unlikely, we recommend strict hygiene measures for all CF patients harbouring NTM.

关键词： Mycobacteria Nontuberculous Mycobacterium abscessus Cystic Fibrosis Molecular Epidemiology Multilocus Sequence Analysis(MLSA) Interferon Gamma

过渡期内用临时限位栏代替永久限位栏以提高母猪福利研究概况

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猪业科学 2019年第2期36卷 30-31页

作者：张振玲 Wackermannova Marie Goumon Sébastien Illmann gudrun 徐州生物工程职业技术学院动物工程系江苏徐州221006

众所周知,限位栏是20世纪80年代兴起的一种适宜于工厂化养猪模式的养殖设备。在给人们带来生产管理上的便利以及效益的同时,限位栏也给母猪带来了巨大的伤害,因而也成为众多人士攻击的目标。有人说这是让母猪“坐水牢”,有人把它当成母... 详细信息

众所周知,限位栏是20世纪80年代兴起的一种适宜于工厂化养猪模式的养殖设备。在给人们带来生产管理上的便利以及效益的同时,限位栏也给母猪带来了巨大的伤害,因而也成为众多人士攻击的目标。有人说这是让母猪“坐水牢”,有人把它当成母猪的“隐形杀手”。早在2001年,欧盟就已向业界公布了使用限位栏禁令的概念,但是直到2013年,欧盟才正式出台对妊娠期母猪使用限位栏的新规定。但在我国动物福利标准中仍没有明确今后在母猪的饲养中禁止使用限位栏,限位栏是我国目前最能提高母猪生产效率的饲养方式。

关键词：限位栏猪福利永久饲养方式养殖设备养猪模式生产管理隐形杀手