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世界核心医学期刊文摘（皮肤病学分册） 2006年第10期2卷 36-37页

作者： gudi v. Ormerod A.D. Dawn G. G.Gupta 罗素菊 Department of Dermatology Monklands HospitalAirdrie ML6 0JSUnited Kingdom Dr.

*** British Association of Dermatologists(BAD)has produced guidelines for management of basal cellcarcinoma(BCC)in the *** primary objectives were to assess the management of BCCs in Scotland and to compare it with BAD *** secondary objectives were to audit waiting times and referral *** phase I of the aud it,dermatologists in 14 centres across Scotl and prospectively registered demographic and clinical data of all lesions suspected to be BCCs over a 6-week period between October and December *** phase II,details of management of these lesions were evaluated by case note *** the 48 consultant dermatologists contacted,42 took part in the *** were 524 clinically suspected BCCs seen in 470 patients;164 lesions in 146 patients showed pathology other than BCC and were excluded from analysis,thus leaving 360 lesions available for *** was wide variation in waiting times among Scottish dermatology *** were equally distributed between the sexes,and lesions most commonly presented in those aged 71-80 years.A diagnostic biopsy was taken in 22%of lesions,and the rest were treated definitively after a clinical diagnosis of BCC,of which 90%were confirmed on *** lesions were the most common type of tumour,comprising 48%of lesions,and most BCCs were located on the head and neck *** of the histological type of BCC and treatment received showed that nodulocystic and morpheic BCCs were managed as *** were more superficial BCCs treated with surgical excision than expected(22 of 34 lesions).Four of 21 recurrent tumours and 9 of 81 tumours on high-risk areas of the face were managed with curettage and cautery or cryotherapy,rather than surgical *** the 297 excised tumours,25(9%)were incompletely *** the high-risk tumours and incompletely excised tumours were offered follow-up in the dermatology *** general,BC

关键词：基底细胞癌皮肤科医生皮肤科会诊病例记录囊肿型等待时间回顾法刮除术分析范围临床资料

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苏格兰东北部格兰扁地区大疱性类天疱疮的年发病率和死亡率

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世界核心医学期刊文摘（皮肤病学分册） 2005年第11期1卷 40-40页

作者： gudi v.S. White M.I. Cruickshank N. 刘艳 Department of Dermatology Aberdeen Royal Infirmary Aberdeen AB25 2ZN United Kingdom

Background: Data on the annual incidence of bullous pemphigoid (BP) in the U.K. are scarce. Objectives: To estimate the annual incidence of BP in Grampian Region (North-east Scotland) and to assess the causes of mortality in this cohort of patients. Methods: Details were obtained of all patients with a diagnosis of BP recorded in the database of the Pathology Department, Aberdeen Royal Infirmary between January 1991 and December 2001. Community Health Index population data were obtained from the Grampian Health Board and the annual incidence and age-and sex-specific incidence were calculated. Mortality data were obtained from the Patient Administration System and causes of death obtained from the Office of the Registrar for Births and Deaths for Scotland. Results: Eighty-three patients met criteria for diagnosis of BP. The annual incidence of BP in Grampian region was estimated to be 14 cases per million per year. There was a clear and marked rise in the incidence in patients over the age of 80 years. Forty-eight per cent of patients with BP died within 2 years of diagnosis. The all-cause age-standardized mortality ratio was 576%. When compared with cause-specific mortality in the Grampian population over 60 years of age, respiratory disease accounted for a higher than expected number of deaths in our cohort of patients with BP (odds ratio 5.3, 95%confidence interval 3.0-9.4). Conclusions: North-east Scotland appears to have a relatively high incidence of BP when compared with incidence rates in continental Europe. The mortality rate in patients with BP is considerable, especially within the first 2 years of diagnosis.

关键词：大疱性类天疱疮死亡登记死亡原因死亡数据患者群柏丁社区健康患者管理指数数据医院病理科

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每日与每周局部应用5%氟尿嘧啶(Efudix~霜)治疗光化性角化病的随机试验

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世界核心医学期刊文摘（皮肤病学分册） 2006年第1期2卷 41-41页

作者： Jury C.S Ramraka-Jones v.S gudi v Herd R.M 罗素菊 Department of Dermatology Western Infirmary North Glasgow Hospitals University Glasgow United Kingdom

Background: Topical 5-fluorouracil (5-FU) cream is widely used in the treatment of actinic keratoses (AKs) but the optimumtreatment regimen that provides efficacywhileminimizing side-effects remains unclear. Objectives A randomized trial to compare the efficacy and side-effects of daily vs. weekly application of 5%5-FU in the treatment of AKs of the scalp and face. Patients/methods Twenty patients were recruited and randomized to two groups. Group 1 (13 patients) appl ied 5%5-FU twice daily for 3 weeks, group 2 (seven patients) applied 5%5-FU twice daily for 1 day per week for 12 weeks. Patients were reviewed at weeks 3, 12, 24 and 52. At each review a lesion count and lesion map were completed and p atients were asked to score efficacy and inflammation. Results At week 0 the med ian lesion count was the same in both groups, 17.5 lesions. At 12 weeks the medi an lesion count in group 1 had fallen to 0 where it remained for the duration of follow-up. In group 2 the median lesion count fell to 6 at 12 weeks, 5.5 at 24 weeks and was 3 at 52 weeks. The difference in the lesion count was significant at all time points after week 0: P ve than weekly application at clearing AKs from the scalp a nd face. Our results also suggest that inflammation is likely to be required to achieve a therapeutic effect.

关键词：光化性角化病 Efudix 尿嘧啶局部应用随机试验最佳治疗方法皮损数目炎症反应中位值评

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无机砷胁迫下苗期水稻的生理响应

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农产品加工（下） 2009年第2期 4-6页

作者：杨桂娣郭徐魁刘长辉陆锦池陈荣山宋凤琴林志华王海斌何海斌福建农林大学生命科学学院福建福州350002

探讨水培条件下,不同形态的无机砷(As2O3和HAsNa2O)4对苗期水稻生理特性的影响。结果表明,随着砷浓度的升高,水稻根和叶中超氧化物歧化酶、过氧化物酶和过氧化氢酶的活性受到了显著抑制,根中的抑制程度较叶中大;利用ICP—MS测定砷含量... 详细信息

探讨水培条件下,不同形态的无机砷(As2O3和HAsNa2O)4对苗期水稻生理特性的影响。结果表明,随着砷浓度的升高,水稻根和叶中超氧化物歧化酶、过氧化物酶和过氧化氢酶的活性受到了显著抑制,根中的抑制程度较叶中大;利用ICP—MS测定砷含量的结果表明,随着砷浓度的升高,水稻组织中砷含量增加,其根中砷含量的增加尤其明显。同时本研究还发现As(II)I的毒性大于As(v)。

关键词：无机砷水稻生理特性

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