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Emerging SARS-CoV-2 B.1.621/Mu variant is prominently resistant to inactivated vaccine-elicited antibodies

Zoological Research 2021年第6期42卷 789-791页

作者： Xiaochun Xie Jian-Bao Han guanqin ma Xiao-Li Feng Xiaohong Li Qing-Cui Zou Zhong-Hua Deng Jianxiong Zeng Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650201China Kunming National High-level Biosafety Research Center for Non-Human Primates Center for Biosafety Mega-ScienceKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China National Resource Center for Non-Human Primates National Research Facility for Phenotypic&Genetic Analysis of Model Animals(Primate Facility)Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China

Although it first appeared almost two years ago,the COVID-19 pandemic continues to have an impact on a global scale,in part due to newly emerging SARS-CoV-2 variants such as Delta and *** B.1.621 variant,first identified in Colombia in January 2021,was classified as a variant of interest(VOI)and designated as Mu by the World Health Organization(WHO)in August ***,its infectivity and resistance to neutralizing antibodies remain largely ***,in comparison to Delta,the Mu variant showed an unexpectedly enhanced immune resistance to inactivated vaccine-elicited ***,Mu demonstrated less infectivity than Delta,implying a biological trade-off between viral transmission and immune *** study strongly calls for urgent evaluation of the protective efficacy of current COVID-19 vaccines against the Mu *** of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)are of concern regarding control of the global COVID-19 pandemic(Wang et al.,2021).The SARS-CoV-2 B.1.621 variant was first identified in Colombia in January *** its epidemiological prevalence,the WHO defined B.1.621(named Mu)as a VOI on 30 August *** of September 2021,the WHO has classified four variants of concern(VOC),i.e.,Alpha(B.1.1.7),Beta(B.1.351),Gamma(P.1),and Delta(B.1.617.2),and two VOI,i.e.,Lambda(C.37)and Mu(B.1.621)(Supplementary Figure S1A).

关键词： Figure protective continue

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稀燃天然气发动机缸压数据采集及循环变动分析

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北京交通大学学报 2008年第4期32卷 44-47,51页

作者：姚宝峰胡琰马冠钦郑亚银李国岫北京交通大学机械与电子控制工程学院北京100044

运用虚拟仪器技术开发了天然气发动机缸内压力信号采集和分析系统.系统以软件为核心代替了大部分硬件功能,采集精度达到0.18°CA,并能够有效滤除信号中的噪声,满足连续多循环采集与分析的要求.利用计算燃烧循环变动系数与重构缸内压力... 详细信息

运用虚拟仪器技术开发了天然气发动机缸内压力信号采集和分析系统.系统以软件为核心代替了大部分硬件功能,采集精度达到0.18°CA,并能够有效滤除信号中的噪声,满足连续多循环采集与分析的要求.利用计算燃烧循环变动系数与重构缸内压力时间序列相空间的方法对当量比对天然气发动机燃烧循环变动的影响进行了研究.结果表明,当量比越小燃烧循环变动越明显,缸内压力相空间中曲线簇的发散现象就更加明显.

关键词：发动机天然气数据采集循环变动

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基于动力学的发动机正时皮带怠速噪声仿真分析及试验研究

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内燃机工程 2019年第5期40卷 81-85页

作者：梁善飞郭丰张勇刚马冠钦杨万里王瑞平宁波吉利罗佑发动机零部件有限公司宁波315000 同济大学机械与能源工程学院上海200092

以某3缸增压直喷汽油机正时皮带怠速低频噪声为研究对象,通过试验锁定噪声源和噪声频段,并对该噪声产生机理进行分析。针对该噪声源和噪声频段,通过一维动力学仿真的方法来优化正时皮带系统的布置参数,寻找到降低该噪声的方法,并最终通... 详细信息

以某3缸增压直喷汽油机正时皮带怠速低频噪声为研究对象,通过试验锁定噪声源和噪声频段,并对该噪声产生机理进行分析。针对该噪声源和噪声频段,通过一维动力学仿真的方法来优化正时皮带系统的布置参数,寻找到降低该噪声的方法,并最终通过噪声振动平顺性(NVH)试验验证了提高皮带刚度和增加小惰轮的方案能够有效降低该噪声。

关键词：正时皮带怠速噪声动力学仿真噪声-振动-平顺性(NVH)试验汽油增压直喷

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Local magnetic moment oscillation around an Anderson impurity on graphene

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 192-201页

作者： Shuai Li Zhen ma Jin-Hua Gao School of Science Hebei University of Science and Technology School of Electronics and Information Zhengzhou University of Light Industry School of Physics and Wuhan National High magnetic Field Center Huazhong University of Science and Technology

We theoretically investigate the spin resolved Friedel oscillation （FO） and quasiparticle interference （QPI） in graphene induced by an Anderson *** the impurity becomes magnetic,the resulted FO becomes spin dependent,which gives rise to a local magnetic moment oscillation with an envelop decaying as r-2in real space in the doping ***,at half filling,the electron density and local magnetic moment will not oscillate but decay as *** spin resolved FO has both sublattice and spin ***,the local magnetic moment decay at half filling only occurs at one sublattice of graphene,which is quite like the phenomenon observed in the STM experiment (***ález-Herrero et al.,Science 352,437 （2016）).We further give an analytic formula about such spin dependent FO based on the stationary phase ***,we study the interference of quasiparticles around the magnetic impurity by calculating the spin dependent Fourier-transformed local density of states （FT-LDOS）.Our work gives a comprehensive understanding about the local magnetic moment oscillation around an Anderson impurity on graphene.

关键词： Friedel oscillation local magnetic moment graphene Anderson impurity

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贵州省异戊二烯浓度分布及日变化情况初步分析

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地球与环境 2024年第3期52卷 277-285页

作者：罗皓李启泰左仁慧刘芳谢凯夫曹骅马关琴李函颖章婷贵州环科环保咨询有限公司贵阳550081 贵州省环境科学学会贵阳550081 贵州师范大学生命科学学院贵阳550025 贵州师范大学地理与环境科学学院贵阳550025 贵州中咨环科科技有限公司贵阳550081

为了了解贵州省环境空气异戊二烯的浓度水平及分布情况,以贵州省2019年臭氧污染较为严重的地区为研究区域选取了18个采样点,这18个点位包括了工业区、城市建成区、居民区、交通枢纽等排放人为源挥发性有机物(AVOCs)的区域,和水生植物种... 详细信息

为了了解贵州省环境空气异戊二烯的浓度水平及分布情况,以贵州省2019年臭氧污染较为严重的地区为研究区域选取了18个采样点,这18个点位包括了工业区、城市建成区、居民区、交通枢纽等排放人为源挥发性有机物(AVOCs)的区域,和水生植物种植区、森林植被覆盖区、自然风景区等排放植物源挥发性有机物(BVOCs)的区域,尤其以水生植物种植区的异戊二烯观测为重点,在2020年7~9月期间分批次进行了环境空气异戊二烯的离线采样和臭氧浓度的同步在线监测。结果表明,贵州省大气异戊二烯日均浓度在0.13~6.13μg/m^(3)之间,其中BVOCs采样区域、AVOCs采样区域、水生植物种植区、森林植被覆盖区的异戊二烯日均浓度分别为1.74、0.52、2.26、1.23μg/m^(3),白天平均浓度分别为2.80、0.54、4.03、1.57μg/m^(3),夜间平均浓度分别为0.68、0.50、0.49、0.88μg/m^(3),BVOCs采样区域的异戊二烯日均浓度、白天浓度高于AVOCs采样区,夜间浓度差异不大;水生植物种植区的日均浓度和白天浓度高于森林植被覆盖区,这表明贵州部分地区水生植物在夏季白天的异戊二烯排放比森林植被等陆生植物要高,水生植物(荷花、芦苇、慈姑等)排放的异戊二烯对环境的影响值得关注并深入研究。

关键词：贵州省异戊二烯水生植物

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Transient receptor potential channels and calcium dysregulation: a pathogenic duo in Parkinson's disease

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Neural Regeneration Research 2025年第3期20卷 808-810页

作者： Iqira Saeed Linlin ma Griffith Institute for Drug Discovery Griffith UniversityNathanBrisbaneQLDAustralia School of Environment and Science Griffith University NathanBrisbaneQLDAustralia

Parkinson's disease(PD) has a complex and multifactorial pathophysiology. Various studies, conducted both in pre-clinical models and PD patients, have reported a link between the disruption of calcium(Ca^(2+)) homeostasis and the subsequent development of PD. Ca^(2+) regulation is crucial for neuronal survival, differentiation,exocytosis at synapses,gene transcription,and proliferation.

关键词： homeostasis clinical subsequent

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Harnessing therapeutic potential of induced pluripotent stem cell–derived endothelial cells for remyelination in the central nervous system

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Neural Regeneration Research 2025年第6期20卷 1715-1716页

作者： Dan ma Nona Pop Aston Medical School College of Health and Life SciencesAston UniversityBirminghamUK

Myelin is the protective sheath surrounding nerve fibers, and its damage(demyelination) occurs in many central nervous system(CNS) diseases, including multiple sclerosis(MS), traumatic injury, neurodegenerative diseases such as Alzheimer's disease, and mental disorders such as schizophrenia(Barateiro et al., 2016). Repair of damaged myelin sheaths(remyelination) often fails in MS, leading to neuronal loss and irreversible functional deficits.

关键词： myelin protective diseases

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magnetron sputtered nickel oxide with suppressed interfacial defect states for efficient inverted perovskite solar cells

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Journal of Energy Chemistry 2025年第1期100卷 348-355页

作者： Guoqiang ma Qin Tan Zhaoning Li Jingwei Xiu Jiafeng Wang Tianle Cheng Dong He Qiang Sun Xuhang ma Francesco Lamberti Zhubing He Department of materials Science and Engineering Institute of Innovative Materials (I2M) Shenzhen Key Laboratory of Full Spectral Solar Electricity Generation (FSSEG)Southern University of Science and Technology (SUSTech) Core Research Facilities Southern University of Science and Technology Department of Chemical Sciences Department of Industrial Engineering University of Padova

Widely used spin-coated nickle oxide （NiOx） based perovskite solar cells often suffer from severe interfacial reactions between the NiOxand adjacent perovskite layers due to surface defect states,which inherently impair device performance in a long-term view,even with surface molecule *** this study,we developed high-quality magnetron-sputtered NiOxthin films through detailed process optimization,and compared systematically sputtered and spin-coated NiOxthin film surfaces from materials to *** sputtered NiOxfilms exhibit improved crystallinity,smoother surfaces,and significantly reduced Ni3+or Ni vacancies compared to their spin-coated ***,the interface between the perovskite and sputtered NiOxfilm shows a substantially reduced density of defect *** solar cells （PSCs） fabricated with our optimally sputtered NiOxfilms achieved a high power conversion efficiency （PCE） of up to 19.93%and demonstrated enhanced stability,maintaining 86.2% efficiency during 500 h of maximum power point tracking under one standard sun ***,with the surface modification using (4-(2,7-dibromo-9,9-dimethylacridin-10（9H）-yl)butyl)p hosphonic acid （DmacPA）,the device PCE was further promoted to 23.07%,which is the highest value reported for sputtered NiOxbased PSCs so far.

关键词： Nickle oxide magnetron sputter Defect Stability Perovskite solar cell

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Morphology engineering of ZnO micro/nanostructures under mild conditions for optoelectronic application

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International Journal of Minerals,Metallurgy and materials 2025年第2期32卷 498-503页

作者： Liang Chu Haoyu Shen Hudie Wei Hongyu Chen Guoqiang ma Wensheng Yan Institute of Carbon Neutrality and New Energy&School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China School of Applied Physics and materials Wuyi UniversityJiangmen 529020China

Zinc oxide(ZnO)serves as a crucial functional semiconductor with a wide direct bandgap of approximately 3.37 *** reaction is commonly used in the synthesis of ZnO micro/nanostructures,given its low cost,simplicity,and easy ***,ZnO morphology engineering has become desirable through the alteration of minor conditions in the reaction process,particularly at room *** this work,ZnO micro/nanostructures were synthesized in a solution by varying the amounts of the ammonia added at low temperatures(including room temperature).The formation of Zn^(2+)complexes by ammonia in the precursor regulated the reaction rate of the morphology engineering of ZnO,which resulted in various structures,such as nanoparticles,nanosheets,microflowers,and single ***,the obtained ZnO was used in the optoelectronic application of ultraviolet detectors.

关键词： morphology engineering low temperature ZnO nanosheets microflowers ultraviolet detector

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基于NEDC循环的增压直喷汽油机颗粒物排放控制

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小型内燃机与车辆技术 2019年第1期48卷 67-73页

作者：张毅李基凤马冠钦杨万里王瑞平宁波吉利罗佑发动机零部件有限公司浙江宁波315336 浙江吉利罗佑发动机有限公司

为了研究涡轮增压缸内直喷汽油机(TGDI)匹配整车在NEDC循环时颗粒物排放特性,以一款1.5L TGDI发动机为研究对象,在发动机台架上运行车辆NEDC循环对应的发动机工况来测试初始PM(Particulate matter)与PN(Particulate Number)。该发动机初... 详细信息

为了研究涡轮增压缸内直喷汽油机(TGDI)匹配整车在NEDC循环时颗粒物排放特性,以一款1.5L TGDI发动机为研究对象,在发动机台架上运行车辆NEDC循环对应的发动机工况来测试初始PM(Particulate matter)与PN(Particulate Number)。该发动机初始PM为10 mg/km,PN为12×1013。PM排放不满足欧五,PN排放不满足欧六B,PM与PN排放均不满足开发目标。通过燃油二次喷射,优化二次喷射点火角,优化启动阶段空燃比,优化三元催化器加热时间与油轨压力,最终使PM降为1 mg/km,PN降为2.5×1012,满足欧六B与开发目标。研究表明:汽油二次喷射可以降低50%的颗粒物排放;三元催化器加热时间由60 s增加至80 s,可以降低10%的PN排放;PN与PM随着轨压压力的升高,先降低后升高,轨压压力0.8 MPa为最优方案。

关键词：增压直喷汽油机颗粒物二次喷射点火角

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