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Association Between COVID-19 Vaccination Coverage and Case Fatality Ratio:a Comparative Study—Hong Kong SAR,China and Singapore,December 2021–March 2022

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China CDC weekly 2022年第30期4卷 649-654,I0002-I0004页

作者： guanhao He Sui Zhu Di Fu Jianpeng Xiao Jianguo Zhao Ziqiang Lin Tao Liu Xiaofeng liang Wenjun Ma Department of Public Health and Preventive Medicine School of MedicineJinan UniversityGuangzhou CityGuangdong ProvinceChina Disease Control and Prevention Institute Jinan UniversityGuangzhou CityGuangdong ProvinceChina Guangdong Provincial Institute of Public Health Guangdong Provincial Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina.

Summary What is already known about this topic?Hong Kong Special Administrative Region(SAR),China and Singapore are both facing considerable Omicron variant epidemic.However,the overwhelmed medical system and high case fatality ratio(CFR)just occurred in Hong Kong SAR,China but not in Singapore.What is added by this report?The low vaccination coverage in Hong Kong SAR,China,especially among the older adults,is shown to be a primary reason of its recent high CFR.What are the implications for public health practice?Facing the potential epidemic risk,non-vaccinated,non-fully-vaccinated,and non-booster-vaccinated people in China,especially the elderly,should get any type of accessible vaccine,which could save lives when the infection unfortunately befalls.

关键词： SAR Singapore CFR

Effectiveness of COVID-19 Vaccination Against SARS-CoV-2 Omicron Variant Infection and Symptoms—China,December 2022–February 2023

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China CDC weekly 2023年第17期5卷 369-373,I0001-I0005页

作者： Di Fu guanhao He Huanlong Li Haomin Tan Xiaohui Ji Ziqiang Lin Jianxiong Hu Tao Liu Jianpeng Xiao Xiaofeng liang Wenjun Ma Department of Public Health and Preventive Medicine School of MedicineJinan UniversityGuangzhou CityGuangdong ProvinceChina Disease Control and Prevention Institute Jinan UniversityGuangzhou CityGuangdong ProvinceChina Key Laboratory of Ministry of Education for Viral Pathogenesis&Infection Prevention and Control Jinan UniversityGuangzhou CityGuangdong ProvinceChina Fuyang District Center for Disease Control and Prevention Hangzhou CityZhejiang Province Guangdong Provincial Institute of Public Health Guangdong Provincial Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina

Summary What is already known about this topic?A considerable percentage of the population has received both primary and booster vaccinations,which could potentially provide protection against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron infections and related symptoms.What is added by this report?The self-reported infection rate,as determined from an online survey,reached its peak(15.5%)between December 19 and 21,2022,with an estimated 82.4%of individuals in China being infected as of February 7,2023.During the epidemic,the effectiveness of booster vaccinations against SARS-CoV-2 Omicron infection was found to be 49.0%within three months of vaccination and 37.9%between 3 and 6 months following vaccination.Furthermore,the vaccine effectiveness of the booster vaccination in relation to symptom prevention varied from 48.7%to 83.2%within three months and from 25.9%to 69.0%between 3 and 6 months post-booster vaccination.

关键词： vaccination prevention acute

Hybrid undulatory kinematics of a robotic Mackerel(Scomber scombrus):Theoretical modeling and experimental investigation

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Science China(Technological Sciences) 2012年第10期55卷 2941-2952页

作者： WEN Li WANG TianMiao WU guanhao liang JianHong Museum of Comparative Zoology Harvard University26 Oxford StreetCambridgeMA 02138USA Robotic Institute in School of Mechanical Engineering and Automation Beihang UniversityBeijing 100191China State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentsTsinghua UniversityBeijing 100084China

Fishes that use undulatory locomotion occasionally change their inherent kinematics in terms of some natural behavior.This special locomotion pattern was vividly dubbed "hybrid kinematics" by biologists recently.In this paper,we employed a physical model with body shape of a Mackerel(Scomber scombrus),to use the three most typical undulatory kinematics:anguillform,carangiform and thunniform,to investigate the hydrodynamic performance of the so-called "hybrid kinematics" biological issue.Theoretical models of both kinematics and hydrodynamics of the physical model swimming were developed.Base on this model,the instantaneous force produced by fish undulatory body and flapping tail were calculated separately.We also quantitatively measured the hydrodynamic variables of the robotic model swimming with the three undulatory kinematics on an experimental apparatus.The results of both theoretical model and experiment showed that the robot with thunniform kinematics not only reaches a higher speed but also is more efficient during steady swimming mode.However,anguilliform kinematics won the speed race during the initial acceleration.Additionally,the digital particle image velocimetry(DPIV) results showed some difference of the wake flow generated by the robotic swimmer among the three undulatory kinematics.Our findings may possibly shed light on the motion control of a biomimetic robotic fish and provide certain evidence of why the "hybrid kinematics" exists within the typical undulatory locomotion patterns.

关键词：机器人模型波状运动物理模型实验装置鲭鱼混合型数字粒子图像测速流体动力学

Long-Term Trend Analysis of Major Human Helminth Infections — Guangdong Province, China, 1988–2021

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China CDC weekly 2022年第41期4卷 912-919,I0002-I0007页

作者： Yueyi Fang Jiong Wang guanhao He Qiming Zhang Jianpeng Xiao Jianxiong Hu Zuhua Rong Lihua Yin Fangfang Zeng Pan Yang Xiaomei Dong Dan Liu Xiaofeng liang Zhuohui Deng Tao Liu Wenjun Ma Guangdong Provincial Center for Disease Control and Prevention Guangzhou CityGuangdong ProvinceChina School of Public Health Southern Medical UniversityGuangzhou CityGuangdong ProvinceChina Department of Public Health and Preventive Medicine School of MedicineJinan UniversityGuangzhou CityGuangdong ProvinceChina Disease Control and Prevention Institute of Jinan University Jinan UniversityGuangzhou CityGuangdong ProvinceChina Guangdong Provincial Institute of Public Health Guangdong Provincial Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina.&Joint first authors

Introduction:Although helminth infections threaten millions of people worldwide,the spatiotemporal characteristics remain unclear across China.This study systematically describes the spatiotemporal changes of major human helminth infections and their epidemiological characteristics from 1988 to 2021 in Guangdong Province,China.Methods:The survey data in Guangdong Province were primarily obtained from 3 national surveys implemented during 1988–1992,2001–2004,and 2014–2016,respectively,and from the China Information System for Disease Control and Prevention during 2019–2021.A modified Kato-Katz technique was used to detect parasite eggs in collected fecal samples.Results:The overall standardized infection rates(SIRs)of any soil-transmitted helminths(STH)and Clonorchis sinensis decreased from 65.27%during 1988–1992 to 4.23%during 2019–2021.In particular,the SIRs of STH had even more of a decrease,from 64.41%during 1988–1992 to 0.31%during 2019–2021.The SIRs of Clonorchis sinensis in the 4 surveys were 2.40%,12.17%,5.20%,and 3.93%,respectively.This study observed different permutations of gender,age,occupation,and education level on the SIRs of helminths.Conclusions:The infection rate of STH has substantially decreased.However,the infection rate of Clonorchis sinensis has had fewer changes,and it has become the dominant helminth.

关键词： occupation Guangdong education

When and How to Adjust Non-Pharmacological Interventions Concurrent with Booster Vaccinations Against COVID-19—Guangdong,China,2022

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China CDC weekly 2022年第10期4卷 199-206,I0002-I0012页

作者： guanhao He Fangfang Zeng Jianpeng Xiao Jianguo Zhao Tao Liu Jianxiong Hu Sicong Zhang Ziqiang Lin Huaiping Zhu Dan Liu Min Kang Haojie Zhong Yan Li Limei Sun Yuwei Yang Zhixing Li Zuhua Rong Weilin Zeng Xing Li Zhihua Zhu Xiaofeng liang Wenjun Ma Guangdong Provincial Center for Disease Control and Prevention Guangzhou CityGuangdong ProvinceChina Department of Public Health and Preventive Medicine School of MedicineJinan UniversityGuangzhou CityGuangdong ProvinceChina Disease Control and Prevention Institute Jinan UniversityGuangzhou CityGuangdong ProvinceChina Guangdong Provincial Institute of Public Health Guangdong Provincial Center for Disease Control and PreventionGuangzhou CityGuangdong ProvinceChina BNU-HKBU United International College Zhuhai CityGuangdong ProvinceChina Department of Psychiatry School of MedicineNew York UniversityNew York CityNew YorkUnites States Laboratory of Mathematical Parallel Systems(LAMPS) Department of Mathematics and StatisticsYork UniversityToronto CityOntarioCanada Jinan University-BioKangtai Vaccine Institute Jinan UniversityGuangzhou CityGuangdong ProvinceChina

Introduction:With the large-scale roll-out of the coronavirus disease 2019(COVID-19)booster vaccination effort(a vaccine dose given 6 months after completing primary vaccination)in China,we explore when and how China could lift non-pharmacological interventions(NPIs)against COVID-19 in 2022.Methods:Using a modified susceptible-infectiousrecovered(SIR)mathematical model,we projected the COVID-19 epidemic situation and required medical resources in Guangdong Province,China.Results:If the number of people entering from overseas recovers to 20%of the number in 2019,the epidemic in 2022 could be controlled at a low level by a containment(215 local cases)or suppression strategy(1,397 local cases).A mitigation strategy would lead to 21,722 local cases.A coexistence strategy would lead to a large epidemic with 6,850,083 local cases that would overwhelm Guangdong’s medical system.With 50%or 100%recovery of the 2019 level of travelers from overseas,the epidemic could also be controlled with containment or suppression,but enormous resources,including more hotel rooms for border quarantine,will be required.However,coexistence would lead to an uncontrollable epidemic with 12,922,032 local cases.Discussion:With booster vaccinations,the number of travelers from overseas could increase slightly in 2022,but a suppression strategy would need to be maintained to ensure a controllable epidemic.

关键词： maintained Guangdong overseas

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稻飞虱成虫有虫丛率与虫口密度关系的研究

中国农学通报 2013年第33期29卷 333-336页

作者：陈观浩梁盛铭广东省化州市病虫测报站广东化州525100

研究稻飞虱成虫有虫丛率与虫口密度的关系,建立相关模型,为该害虫的预测预报和防治提供科学依据。选取66块田间稻飞虱成虫种群发生的调查数据,用种群密度(y)和有虫丛率(x)分别拟合一元三次函数、一元二次函数、直线函数、幂函数、指数... 详细信息

研究稻飞虱成虫有虫丛率与虫口密度的关系,建立相关模型,为该害虫的预测预报和防治提供科学依据。选取66块田间稻飞虱成虫种群发生的调查数据,用种群密度(y)和有虫丛率(x)分别拟合一元三次函数、一元二次函数、直线函数、幂函数、指数函数和对数函数6种不同模型,并用未建模的10块稻田资料进行验证应用。结果表明,各模型相关系数均达极显著水平,但综合Q、Syx值分析,以一元三次函数模型y=-0.0001x3+0.0196x2+0.8680x+0.1815为最优(Q和Syx值最小);参与验证应用的4个模型,预测精度均在84%以上,其中一元三次函数模型预测精度最高。另外利用优选出来的数学模型建立了稻飞虱虫口密度速查表。该研究结果将对稻飞虱监测预报和防治起到积极作用。

关键词：稻飞虱有虫丛率虫口密度数学模型

冗余自由度工业机器人模糊自适应PID控制研究

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计算机测量与控制 2016年第8期24卷 126-129,133页

作者：葛卓罗庆生梁冠豪北京理工大学机电学院北京100081

为提高汽车生产中涂胶工序的工作效率和空间利用率,改善机器人避障性能,设计了一款具有7自由度的冗余度工业涂胶机器人,并对其控制方法开展研究;针对现有PID控制方法应用于非线性时变的多自由度多刚体串联式开链系统时,控制效果有限、... 详细信息

为提高汽车生产中涂胶工序的工作效率和空间利用率,改善机器人避障性能,设计了一款具有7自由度的冗余度工业涂胶机器人,并对其控制方法开展研究;针对现有PID控制方法应用于非线性时变的多自由度多刚体串联式开链系统时,控制效果有限、难以达到系统精度要求等问题,基于传统PID控制和模糊自适应控制算法,提出了一种带有重力补偿的模糊自适应PID混合控制方法;该方法在对冗余度工业机器人进行动力学分析的基础上,基于牛顿-欧拉分析法建立了冗余度机器人动力学模型,基于动力学分析设计了带有重力补偿的模糊自适应参数整定PID控制策略,建立了控制器模型,通过Matlab仿真实验表明,具有模糊自适应参数整定PID控制较有重力补偿的传统PID控制具有更好的控制效果。

关键词：冗余自由度工业机器人动力学模糊自适应

早稻南方水稻黑条矮缩病发病率预测模型的建立与应用

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中国稻米 2016年第2期22卷 61-64页

作者：董城梁少玉陈冰梁盛铭陈观浩广东省化州市同庆农业技术推广站广东化州525127 广东省化州市长岐农业技术推广站广东化州525128 广东省化州市气象局广东化州525100 广东省化州市病虫测报站广东化州525100

南方水稻黑条矮缩病是近年来在我国南方稻区重发的一种病毒性病害。为了明确生态因子与南方水稻黑条矮缩病发病率的关系,提高预测能力,避免严重损失,笔者利用化州市2007-2015年的生态因子数据与南方水稻黑条矮缩病田间实际发生数据,采... 详细信息

南方水稻黑条矮缩病是近年来在我国南方稻区重发的一种病毒性病害。为了明确生态因子与南方水稻黑条矮缩病发病率的关系,提高预测能力,避免严重损失,笔者利用化州市2007-2015年的生态因子数据与南方水稻黑条矮缩病田间实际发生数据,采用逐步回归和通径分析的方法研究了两者之间的相关性。结果表明,上年10月下旬温雨系数和上年晚稻黑条矮缩病发病率对早稻南方水稻黑条矮缩病发病率影响最大。笔者还建立了生态因子与早稻南方水稻黑条矮缩病发病率回归模型:Y=-2.7590+0.1895 X_1+0.1345 X_2+1.0495 X^3+0.0044 X_4,利用该回归方程对历史资料进行拟合,拟合程度较好,并对2015年进行预报,预报值与实际值相差较小,准确率较高。可见,该模型适宜于化州乃至粤西地区早稻南方水稻黑条矮缩病的预测预报。

关键词：南方水稻黑条矮缩病生态因子逐步回归通径分析预测模型

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南方水稻黑条矮缩病空间分布型及抽样技术

植物保护 2014年第1期40卷 131-133页

作者：陈观浩梁盛铭任惠陈梅珍广东省化州市病虫测报站化州525100 广东省茂名市植物保护站茂名525000

为了探讨南方水稻黑条矮缩病空间分布型及抽样技术,为该病害的准确抽样调查和有效防治提供依据,选取13块稻田逐丛调查资料,应用聚集度指标法、Iwao法和Taylor幂法则,研究了广东西南部南方水稻黑条矮缩病在稻田的空间分布型和抽样技术。... 详细信息

为了探讨南方水稻黑条矮缩病空间分布型及抽样技术,为该病害的准确抽样调查和有效防治提供依据,选取13块稻田逐丛调查资料,应用聚集度指标法、Iwao法和Taylor幂法则,研究了广东西南部南方水稻黑条矮缩病在稻田的空间分布型和抽样技术。结果表明,南方水稻黑条矮缩病病丛空间分布格局随着病丛密度的提高逐步从聚集型向均匀型演变发展。m*-m回归分析表明病丛空间分布的基本成分是个体群,个体间相互吸引,个体群的空间分布型为均匀分布。Taylor幂法则分析表明,南方水稻黑条矮缩病病丛个体的空间分布随着病丛密度的提高而趋向均匀分布。根据南方水稻黑条矮缩病病丛以均匀为主的空间分布特性,田间抽样调查以采用五点或对角线法等较宜。在此基础上提出了理论抽样数:n=(1.96)2/D2(1.287 1/珚x+0.079 9)。

关键词：南方水稻黑条矮缩病空间分布型抽样技术