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Path-Following Control With Obstacle Avoidance of Autonomous Surface Vehicles Subject to Actuator Faults

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IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 956-964页

作者： Li-Ying Hao Gege Dong Tieshan Li Zhouhua peng the School of Marine Electrical Engineering Dalian Maritime UniversityDalian 116026China the School of Automation Engineering University of Electronic Science and Technology of ChinaChengdu 611731the Navigation CollegeDalian Maritime UniversityDalian 116026 the Yangtze Delta Region Institute(Huzhou) Huzhou 313001China

This paper investigates the path-following control problem with obstacle avoidance of autonomous surface vehicles in the presence of actuator faults,uncertainty and external *** surface vehicles inevitably suffer from actuator faults in complex sea environments,which may cause existing obstacle avoidance strategies to *** reduce the influence of actuator faults,an improved artificial potential function is constructed by introducing the lower bound of actuator efficiency *** nonlinear state observer,which only depends on measurable position information of the autonomous surface vehicle,is used to address uncertainties and external *** using a backstepping technique and adaptive mechanism,a path-following control strategy with obstacle avoidance and fault tolerance is designed which can ensure that the tracking errors converge to a small neighborhood of *** with existing results,the proposed control strategy has the capability of obstacle avoidance and fault tolerance ***,the comparison results through simulations are given to verify the effectiveness of the proposed method.

关键词： Actuator faults autonomous surface vehicle(ASVs) improved artificial potential function nonlinear state observer obstacle avoidance

RNA interference reveals chloride channel 7 gene helps short-term hypersalinity stress resistance in Hong Kong oyster Crassostrea hongkongensis

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Journal of Oceanology and Limnology 2024年第4期42卷 1261-1271页

作者： Yeshao peng Ziao CHEN Qiong DENG Zhen JIA Lingxin KONG peng ZHU Youhou XU Zhicai SHE Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation Pinglu Canal and Beibu Gulf Coastal Ecosystem Observation and Research Station of GuangxiCollege of Marine SciencesBeibu Gulf UniversityQinzhou 535011China

The chloride channel 7 gene(CLC 7)of the Hong Kong oyster Crassostrea hongkongensis was cloned and named ChCLC *** cDNA was 2572 bp in length,with a 5′non-coding region containing 25 bp,a 3′non-coding region containing 327 bp,and an open reading frame of 2298 *** 7 has 96.8%and 92.1%homology with CLC 7 of Crassostrea gigas and Crassostrea virginica,respectively,and it was clustered with CLC 7 of *** and ***-PCR showed that ChCLC 7 was expressed in all eight tissues,with the highest in adductor muscle and second in *** ChCLC 7 expression pattern in gill was altered significantly under high salinity stress with an overall upward and then downward *** RNA interference,the expression of ChCLC 7 and survival rate of oyster under high salinity stress was reduced significantly,and so did the concentration of hemolymph chloride ion in 48-96 h after RNA *** believed that ChCLC 7 could play an important role in osmoregulation of *** by regulating Cl^(-)*** study provided data for the analysis of molecular mechanism against oyster salinity stress.

关键词： Crassostrea hongkongensis chloride channel 7 salinity stress RNA interference

Flexible electrochemical fiber sensor for intracranial nitric oxide monitoring

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Science China Chemistry 2024年第8期67卷 2431-2433页

作者： Ziwei Liu Huisheng peng State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceInstitute of Fiber Materials and Devicesand Laboratory of Advanced MaterialsFudan UniversityShanghai 200438China

Real-time and accurate monitoring of vital biomarkers in vivo forms a crucial foundation for health assessment,early intervention,and disease ***,continuous monitoring of intracranial nitric oxide(NO)levels plays a pivotal role in promptly assessing immune responses,neurovirulence,and cerebrovascular diseases[1].Differing from non-real-time monitoring methods like chemiluminescence[2]and fluorescent probes[3],implantable electrochemical sensors excel in simultaneously high temporal resolution,sensitivity,and cost-effectiveness[4].

关键词： prompt electrochemical monitoring

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Allogenic microglia replacement:A novel therapeutic strategy for neurological disorders

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Fundamental Research 2024年第2期4卷 237-245页

作者： Yanxia Rao Bo peng Department of Laboratory Animal Science MOE Frontiers Center for Brain ScienceFudan UniversityShanghai 200032China Department of Neurosurgery Huashan HospitalInstitute for Translational Brain ResearchState Key Laboratory of Medical NeurobiologyMOE Frontiers Center for Brain ScienceMOE Innovative Center for New Drug Development of Immune Inflammatory DiseasesFudan UniversityShanghai 200000China Co-Innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu 226001China

Microglia are resident immune cells in the central nervous system(CNS)that play vital roles in CNS development,homeostasis and disease *** defects in microglia lead to microglial dysfunction,which in turn leads to neurological *** correction of the specific genetic defects in microglia in these disorders can lead to therapeutic *** genetic defect correction approaches are dependent on viral vectorbased genetic defect ***,the viruses used in these approaches,including adeno-associated viruses,lentiviruses and retroviruses,do not primarily target microglia;therefore,viral vector-based genetic defect corrections are ineffective in *** replacement is a novel approach to correct microglial genetic defects via replacing microglia of genetic defects with allogenic healthy *** this paper,we systematically review the history,rationale and therapeutic perspectives of microglia replacement,which would be a novel strategy for treating CNS disorders.

关键词： Microglia Replacement Microglia replacement Microglia depletion Microglia-free niche CSF1R

Optimal Cooperative Secondary Control for Islanded DC Microgrids via a Fully Actuated Approach

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 405-417页

作者： Yi Yu Guo-Ping Liu Yi Huang peng Shi IEEE Shenzhen Key Laboratory of Control Theory and Intelligent Systems Southern University of Science and TechnologyShenzhen 518055China School of Electrical Engineering and Automation Wuhan UniversityWuhan 430072China School of Electrical and Mechanical Engineering the University of AdelaideSA 5005Australia Research and Innovation Centre Obuda University1034 BudapestHungary

DC-DC converter-based multi-bus DC microgrids(MGs) in series have received much attention, where the conflict between voltage recovery and current balancing has been a hot topic. The lack of models that accurately portray the electrical characteristics of actual MGs while is controller design-friendly has kept the issue active. To this end, this paper establishes a large-signal model containing the comprehensive dynamical behavior of the DC MGs based on the theory of high-order fully actuated systems, and proposes distributed optimal control based on this. The proposed secondary control method can achieve the two goals of voltage recovery and current sharing for multi-bus DC MGs. Additionally, the simple structure of the proposed approach is similar to one based on droop control, which allows this control technique to be easily implemented in a variety of modern microgrids with different configurations. In contrast to existing studies, the process of controller design in this paper is closely tied to the actual dynamics of the MGs. It is a prominent feature that enables engineers to customize the performance metrics of the system. In addition, the analysis of the stability of the closed-loop DC microgrid system, as well as the optimality and consensus of current sharing are given. Finally, a scaled-down solar and battery-based microgrid prototype with maximum power point tracking controller is developed in the laboratory to experimentally test the efficacy of the proposed control method.

关键词： DC microgrids distributed control high-order fully actuated system approach linear quadratic regulator microgrid modeling secondary control

Global analysis of basic leucine zipper transcription factors in trifoliate orange and the function identification of PtbZIP49 in salt tolerance

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Horticultural Plant Journal 2024年第1期10卷 115-130页

作者： Yuanyuan Xu Qiuling Hui Meng Li Hongxian peng Yizhong He Changpin Chun Liangzhi peng Xingzheng Fu National Citrus Engineering Research Center Citrus Research InstituteSouthwest UniversityChongqing 400712China

As one of the most widely distributed and highly conserved transcription factors in eukaryotes,basic leucine zipper proteins(bZIPs)are involved in a variety of biological processes in plants,but they are largely unknown in *** this study,56 bZIP family members were identified genome-wide from an important citrus rootstock,namely trifoliate orange(Poncirus trifoliata ***.),and these putative bZIPs were named PtbZIP1—*** PtbZIPs were classified into 13 subgroups by phylogenetic comparison with Arabidopsis thaliana bZIPs(AtbZIPs),and they were randomly distributed on nine known(50 genes)chromosomes and one unknown(6 genes)*** analysis revealed the detailed characteristics of PtPZIPs,including their amino acid length,isoelectric point(pI),molecular weight(MW),predicted subcellular localization,gene structure,and conserved *** of promoter elements suggested the presence of drought,low-temperature,wound,and defense and stress responsive elements,as well as multiple hormone-responsive cis-acting *** expression analysis showed the transcriptional patterns of PtbZIPs in different tissues and under dehydration,high salt,ABA,and IAA *** addition,21 PtbZIPs were predicted to have direct or indirect protein—protein *** these,PtbZIP49 was experimentally proven to interact with PtbZIP1 or PtbZIP11 by using a yeast two-hybrid assay and bimolecular fluorescence complementation(BiFC).Subcellular localization analysis further revealed that PtbZIP1,PtbZIP11,and PtbZIP49 were localized in the ***,PtbZIP49 was functionally identified as having an important role in salt stress via ectopic expression in *** and silenced in trifoliate orange using virus-induced gene silencing(VIGS).This study provided comprehensive information on PtbZIP transcription factors in citrus and highlights their potential functions in abiotic stress.

关键词： bZIP Citrus Trifoliate orange Abiotic stress Expression pattern

Metochalcone induces senescence-associated secretory phenotype via JAK2/STAT3 pathway in breast cancer

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Oncology Research 2024年第5期32卷 943-953页

作者： JIANBO ZHOU FENG WAN BIN XIAO XIN LI CHENG peng FU peng Department of Pharmacology West China School of PharmacySichuan UniversityChengduChina State Key Laboratory of Southwestern Chinese Medicine Resources Chengdu University of Traditional Chinese MedicineChengduChina Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial TechnologySichuan UniversityChengduChina Chengdu No.1 Pharmaceutical Co. Ltd.PengzhouChina Chengdu Push Bio-Technology Co. Ltd.ChengduChina

Breast and lung cancers are the leading causes of mortality and most frequently diagnosed cancers in women and men,respectively,*** the antitumor activity of chalcones has been extensively studied,the molecular mechanisms of isoliquiritigenin analog 2',4',4-trihydroxychalcone(metochalcone;TEC)against carcinomas remain less well *** this study,we found that TEC inhibited cell proliferation of breast cancer BT549 cells and lung cancer A549 cells in a concentration-dependent *** induced cell cycle arrest in the S-phase,cell migration inhibition in vitro,and reduced tumor growth in ***,transcriptomic analysis revealed that TEC modulated the activity of the JAK2/STAT3 and P53 *** triggered the senescence-associated secretory phenotype(SASP)by repressing the JAK2/STAT3 *** mechanism of metochalcone against breast cancer depended on the induction of SASP via deactivation of the JAK2/STAT3 pathway,highlighting the potential of chalcone in senescence-inducing therapy against carcinomas.

关键词： Metochalcone Breast cancer Lung cancer SASP JAK2/STAT3

Will fuel switching ever happened in China’s thermal power sector?The rule of carbon market design

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Frontiers of Engineering Management 2024年第2期11卷 207-230页

作者： Anqi HE Huarong peng Wuhan University Institute for International Studies Wuhan UniversityWuhan 430072China Climate Change and Energy Economics Study Center Economics and Management SchoolWuhan UniversityWuhan 430000China Collaborative Innovation Center for Emissions Trading System by Ministry of Education and Hubei Provincial Government Hubei University of EconomicsWuhan 430200China

To assess the effectiveness of China’s emissions trading scheme(ETS)in facilitating energy structure optimization,we constructed a fuel-switching model utilizing data from 1067 generating units under the Chinese ETS *** model simulates the fuel-switching price in China’s thermal power sector,taking into account various allowance allocation *** results show the following:1)Thermal power plants will transition from coal to gas if the current ETS auction rate surpasses 26%.2)Furthermore,in scenarios where the ETS operates independently,a transition will occur if the carbon allowance market is entirely auction-based and the carbon price attains 119.50 USD/tCO_(2).3)In a collaborative scenario involving both the ETS and a gas feed-in tariff subsidy,a carbon price of 9.39 USD/tCO_(2)will effect a transition from coal to gas,provided both the auction ratio and subsidy price are maximized.

关键词： ETS thermal power plant fuel switching allowance allocation method feed-in tariff subsidy

Associative cultural landscape approach to interpreting traditional ecological wisdom:A case of Inuit habitat

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Frontiers of Architectural Research 2024年第1期13卷 79-96页

作者： peng Zhang Shuai Li Department of Landscape Architecture College of Architecture and Urban PlanningTongji UniversityShanghai 200092China

Global climate change and the accelerated melting of glaciers have raised concerns about the ability to manage ice-snow ***,human ancestors have mastered the ecological wisdom of working with ice-snow environments,but the phenomenon has not yet been articulated in cultural landscape methodologies that emphasize“nature-culture relevance”.The challenging living environment often compels indigenous people to form a strong bond with their surroundings,leading to the creation of long-term ecological wisdom through synergistic relationships with the *** ecological environment is conceptualized as a cognitive space in the form of the landscape,with which the aboriginal community norms and individual spirits continually *** interactions generate numerous non-material cultural evidences,such as culture,art,religion,and other ideological aspects of the *** evidences symbolize the intellectual outcome of the relationship between humans and the landscape,and they create the“spiritual relevance”through personification and *** aim of the study is to explore the traditional ecological wisdom of the Inuit people who live in the harsh Arctic,and analyze the Inuit’s interaction with the landscape through the lens of“associative cultural landscape”,and decode the survival experience that the Inuit have accumulated through their long-term synergy with the Arctic *** findings focus on the synergy between the Inuit and the ice-snow landscape,examining the knowledge and ecological wisdom that the Inuit acquire from the ice-snow *** goal is to develop a perspective of the ecological environment from the viewpoint of aboriginal people and establish a methodology,model,and framework for“associative cultural landscape”that incorporates ethnic non-material cultural *** the results,a total of nine models for interpreting traditional Inuit ecological wisdom are generated based on the“diamond

关键词： Landscape architecture Associative cultural landscape Nature-culture relevance Cultural landscape Traditional ecological wisdom Non-material cultural evidence Methodology Habitat Living environment Ice-snow landscape