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工程建设（维泽科技） 2024年第10期7卷 114-116页

作者：刘金唐广晖刘勇大连市勘察测绘研究院集团有限公司辽宁大连116021

高精度定位技术经历了从传统地面基站到现代卫星和传感器系统的演变。全球导航卫星系统(GNSS)极大地提升了定位精度,惯性导航系统(INS)和地基增强系统(GBAS)进一步增强了在复杂环境中的性能。近年来,多传感器融合和先进的数据处理技术,... 详细信息

高精度定位技术经历了从传统地面基站到现代卫星和传感器系统的演变。全球导航卫星系统(GNSS)极大地提升了定位精度,惯性导航系统(INS)和地基增强系统(GBAS)进一步增强了在复杂环境中的性能。近年来,多传感器融合和先进的数据处理技术,如卡尔曼滤波和人工智能,显著提升了定位技术的精度和应用范围。这些技术的进步为测绘、工程测量、无人驾驶和智能交通等领域提供了关键支持。

关键词：测绘导航高精度定位智能交通

浅析不动产测绘工程质量控制与测绘技术的应用

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智能城市应用 2024年第10期7卷 116-118页

作者：唐广晖刘金刘勇大连市勘察测绘研究院集团有限公司辽宁大连116021

随着科技的飞速发展,不动产测绘技术经历了从传统地面测量到现代高科技遥感技术的重大变革。传统测绘方法虽然在过去发挥了重要作用,但在面对大规模测绘任务、复杂地形或高精度要求时,存在许多局限性。现代技术的引入,特别是遥感技术、... 详细信息

随着科技的飞速发展,不动产测绘技术经历了从传统地面测量到现代高科技遥感技术的重大变革。传统测绘方法虽然在过去发挥了重要作用,但在面对大规模测绘任务、复杂地形或高精度要求时,存在许多局限性。现代技术的引入,特别是遥感技术、全球定位系统(GPS)、地理信息系统(GIS)和激光扫描技术,极大地提高了测绘数据的精度和工作效率。这些技术的进步不仅使得数据采集变得更加高效和可靠,也促进了测绘数据的综合分析和应用。随着测绘技术的进步,对数据质量的要求也随之提高。数据准确性、技术人员的专业素质,以及质量控制流程的规范化,都成为确保测绘结果可靠性的关键因素。基于此,深入探讨不动产测绘中的质量控制问题,了解和应用先进测绘技术,对于推动不动产测绘行业的发展,提升其服务于城市规划和资源管理的能力具有重要意义。

关键词：不动产测绘技术质量控制

花椒棉蚜发生动态、抗药性水平及防治药剂筛选

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中国森林病虫 2024年第4期43卷 9-15页

作者：孙艳李蓉郭曜东耿召俊魏冰瑶唐光辉西北农林科技大学林学院陕西杨陵712100

为明确花椒园棉蚜Aphis gossypii的发生动态、最佳防治时期和抗药性水平,筛选其防治药剂,采用对角线五点抽样法调查花椒园棉蚜的发生动态,室内生物测定陕西省4个市县的棉蚜种群对6种常用药剂的抗性水平,田间筛选棉蚜的最佳防治药剂。结... 详细信息

为明确花椒园棉蚜Aphis gossypii的发生动态、最佳防治时期和抗药性水平,筛选其防治药剂,采用对角线五点抽样法调查花椒园棉蚜的发生动态,室内生物测定陕西省4个市县的棉蚜种群对6种常用药剂的抗性水平,田间筛选棉蚜的最佳防治药剂。结果表明:棉蚜在花椒生长季节均有发生,发生高峰期为5月中旬、7月上旬或8月上旬;韩城地区的棉蚜种群对吡虫啉、啶虫脒、毒死蜱、高效氯氟氰菊酯、联苯菊酯和阿维菌素均表现出抗性,岐山县和凤县的棉蚜种群对6种药剂均无抗药性;氟啶虫酰胺、螺虫乙酯和阿维菌素的室内毒力效果较好,田间试验时50%氟啶虫酰胺水分散粒剂(WG)速效性和持效性较好。4月下旬至5月上旬是防治花椒园棉蚜的关键时期,建议使用氟啶虫酰胺、噻虫嗪或螺虫乙酯等药剂进行防治。

关键词：棉蚜花椒发生规律抗药性水平药剂防治

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Neofusicoccum parvum causing canker of seedlings of Juglans regia in China

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Journal of Forestry Research 2015年第4期26卷 1019-1024页

作者： Zhongdong Yu guanghui tang Shaobin Peng Hui Chen Meizhi Zhai Forestry College Northwest A&F University

Cankered, dying seedlings of Juglans regia were observed in Shaanxi province in the northwest region of China. Neofusicoccum parvum was isolated from these cankered tissues, with the identification based on mor- phology and an ITS-nrDNA sequence. In order to demonstrate how cultures of N. parvum could cause the expected symptoms, artificial infection, using these isolates and re-isolation of the pathogen, was used. This is the first report on this taxon as a walnut canker pathogen in China.

关键词： Forest tree disease ITS-nr-DNA Koch's postulates Neofusicoccum parvum Walnut

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花椒疮痂病的病原鉴定与防治药剂筛选

农药 2024年第4期63卷 285-292页

作者：康家发李果宏杨霞耿召俊李培琴唐光辉西北农林科技大学林学院西部森林生物灾害治理国家林业和草原局重点实验室陕西杨凌712100

[目的]明确花椒疮痂病的病原菌,筛选出对该病害具有较好防治效果的杀菌剂,为其田间防治提供指导。[方法]采用组织分离培养法从采集的花椒疮痂病叶中分离微生物,通过回接试验和柯赫氏法则,证明分离的微生物是否为引起花椒疮痂病的病原菌... 详细信息

[目的]明确花椒疮痂病的病原菌,筛选出对该病害具有较好防治效果的杀菌剂,为其田间防治提供指导。[方法]采用组织分离培养法从采集的花椒疮痂病叶中分离微生物,通过回接试验和柯赫氏法则,证明分离的微生物是否为引起花椒疮痂病的病原菌;通过形态学观察和分子生物学对花椒疮痂病病原菌进行鉴定;采用带毒平板法和田间试验筛选对花椒疮痂病具有良好防治效果的杀菌剂。[结果]经形态学和分子生物学鉴定,花椒疮痂病的病原菌为互隔交链孢(Alternaria alternata)。室内抑菌作用筛选结果表明,咪鲜胺和苯醚甲环唑对花椒疮痂病原菌的抑制作用最显著,其EC50值分别为0.016、0.027 mg/L。田间防效试验结果表明,供试药剂中75%百菌清WP1125 g a.i./hm^(2)和45%咪鲜胺EW 337.5 g a.i./hm^(2)对花椒疮痂病具有良好的预防效果,连续3次喷药后,2种药剂预防效果为87.92%和76.88%。45%咪鲜胺EW 337.5 g a.i./hm^(2)对花椒疮痂病具有一定的治疗效果,连续3次喷药后,防效为59.64%。[结论]花椒疮痂病由互隔交链孢侵染引起,百菌清作为预防药剂具有良好效果;咪鲜胺作为治疗药剂具有良好效果。

关键词：花椒疮痂病病原鉴定互隔交链孢杀菌剂筛选

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陕西地区花椒主要病害的生防菌筛选与鉴定

干旱地区农业研究 2024年第2期42卷 222-230,244页

作者：符晓丁俊园焦嘉卉钟思雨孙孟娇付家佳唐光辉李培琴西北农林科技大学林学院/西部森林生物灾害治理国家林业和草原局重点实验室陕西杨凌712100

为开发针对陕西地区花椒主要病害的生防菌资源,对陕西省宝鸡市凤县花椒根际土壤微生物进行分离培养,并测定了其对花椒的4种靶标病原菌,即干腐病菌(Fusarium zanthoxyli)、黑胫病菌(Phytophthora citrophthora)、根腐病菌(***)和落叶病菌... 详细信息

为开发针对陕西地区花椒主要病害的生防菌资源,对陕西省宝鸡市凤县花椒根际土壤微生物进行分离培养,并测定了其对花椒的4种靶标病原菌,即干腐病菌(Fusarium zanthoxyli)、黑胫病菌(Phytophthora citrophthora)、根腐病菌(***)和落叶病菌(Marssonina sp.)的抑菌活性。结果显示:从花椒根际土壤中共分离到297个微生物菌株,其中105个为真菌,192个为细菌。通过初筛,获得了20个对3种及以上靶标病原菌均具有显著拮抗作用的细菌菌株,经形态学和16S rDNA序列分析,将其中7个鉴定为贝莱斯芽孢杆菌(Bacillus velezensis),5个鉴定为解淀粉芽孢杆菌(***),3个鉴定为伯克霍尔德氏菌属(Burkholderia)的不同种,2个鉴定为安徽黄杆菌(Flavobacterium anhuiense),3个为其他种。经复筛和验证,发现贝莱斯芽孢杆菌P87的生防潜力最强,可以作为花椒病害生物防治的备选菌种。

关键词：花椒根际土壤生防菌筛选鉴定抑菌活性

A targeted covalent inhibitor of p97 with proteome-wide selectivity

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Acta Pharmaceutica Sinica B 2022年第2期12卷 982-989页

作者： Zi Ye Ke Wang Lianguo Chen Xiaofeng Jin Hao Chen guanghui tang Shao Q.Yao Zhiqiang Feng Chong-Jing Zhang State Key Laboratory of Bioactive Substances and Functions of Natural Medicines and Beijing Key Laboratory of Active Substances Discovery and Drugability Evaluation Institute of Materia Medica Peking Union Medical College and Chinese Academy of Medical Sciences Department of Chemistry National University of Singapore

A resurging interest in targeted covalent inhibitors(TCIs)focus on compounds capable of irreversibly reacting with nucleophilic amino acids in a druggable target.p97 is an emerging protein target for cancer therapy,viral infections and neurodegenerative *** efforts were devoted to the development of p97 *** most promising inhibitor of p97 was in phase 1 clinical trials,but failed due to the off-target-induced toxicity,suggesting the selective inhibitors of p97 are highly *** report herein a new type of TCIs(i.e.,FL-18)that showed proteome-wide selectivity towards *** with a Michael acceptor and a basic imidazole,FL-18 showed potent inhibition towards U87 MG tumor cells,and in proteome-wide profiling,selectively modified endogenous p97 as confirmed by in situ fluorescence scanning,label-free quantitative proteomics and functional ***-18 selectively modified cysteine residues located within the D2 ATP site of *** covalent labeling of cysteine residue in p97 was verified by LC-MS/MS-based site-mapping and site-directed *** structure-activity relationship(SAR)studies with FL-18 analogs were ***,FL-18 is the first known small-molecule TCI capable of covalent engagement of p97 with proteome-wide selectivity,thus providing a promising scaffold for cancer therapy.

关键词： p97 Activity-based protein profiling Targeted covalent inhibitor Chemical proteomics

Effects of Intracratonic Strike-slip Fault on the Differentiation of Carbonate Microfacies: A Case Study of a Permian Platform Margin in the Sichuan Basin(SW China)

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Acta Geologica Sinica(English Edition) 2024年第4期98卷 936-954页

作者： LIU Jiawei WU guanghui tang Qingsong WU Yonghong ZHANG Wenjin ZHAO Zhongyu School of Geoscience and Technology Southwest Petroleum UniversityChengdu 610500China Qiangtang Basin Research Institute Southwest Petroleum UniversityChengdu 610500China Southwest Petroleum University Division of Key Laboratory of Carbonate Reservoirs of CNPCChengdu 610500China PetroChina Southwest Oil&Gasfield Company Chengdu 610051China

In intracratnoic basins, the effect of strike-slip faults on sedimentary microfacies is generally underestimated due to their small scale. Based on the integration of core, well logs, and three-dimensional seismic data, this study presents a comprehensive analysis of the Permian carbonate platform and strike-slip faults in the southwestern Kaijiang-Liangping trough of the Sichuan Basin. The relationship between strike-slip faults and Permian carbonate microfacies is investigated. The results reveals the existence of a NW-trending strike-slip fault zone along the platform margin, exhibiting clear segmentation. The western side of the study area exhibits a rimmed platform margin characterized by type I reefs, which corresponds to the presence of a large-scale strike-slip fault zone. In contrast, the eastern side is characterized by a norimmed and weak rimmed platform margin, accompanied by type II reefs, which align with smaller strike-slip fault zones. It was found that the strike-slip fault had some effects on the platform and reef-shoal complex of the Permain Changxing Formation. First, the platform was divided by strike-slip fault into three segments to show rimmed, week rimmed and norimmed platform. Second, reef-shoal complex devolped along the faulted high position in the strike-slip fault zone, and separated by faulted depression. Third, strike-slip faults can offset or migrated the reef-shoal complex and platform margin. Additionally, the thickness of the platform margin varies across strike-slip fault zone, which is related to the activity of strike-slip faults. The strike-slip faults affect the microfacies by controlling the pre-depositional paleotopography. This case suggests that the strike-slip faults play a crucial role in the diversity and distribution of carbonate microfacies in the intracratonic basin.

关键词： strike-slip faults segmentation carbonate platform sediment dispersal pattern Changxing Formation Kaijiang–Liangping trough Sichuan Basin

Cooperative NHC/Photoredox Catalysis:Three-Component Reaction of Aroyl Fluorides,Styrenes and Oxalates

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Chinese Journal of Chemistry 2024年第5期42卷 511-515页

作者： Zheng Lin guanghui Lv Jianghong Liu Jiangyan tang Binsong Mu Jian Chen Tianle Huang Zhongzhen Yang Yong Wu Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial TechnologyWest China School of PharmacySichuan UniversityChengduSichuan610041 China Department of Pharmacy Hubei Provincial Clinical Research Center for Umbilical Cord Blood Hematopoietic Stem CellsTaihe HospitalHubei University of MedicineShiyanHubei442000 China

Cooperative NHC/photoredox catalysis has emerged as an important research field in recent ***,this article describes the use of cesium salt derivatives of tert-alcohols as alkyl radical precursors in a three-component reaction with styrene and aromatic acyl fluorides to synthesizeα-arylalkyl aryl *** aroyl fluoride reacts with the NHC catalyst,leading to the formation of an acyl azolium *** acyl azolium ion can then be reduced by the photoredox catalyst,generating the corresponding ketyl radical *** C-radical generated from oxalate oxidation undergoes an addition reaction with the styrene derivative,followed by cross-coupling of the addition radical with the ketone radical,which is fragmented by NHC to give the target ketone.

关键词： Three-component Photoredox NHC Aryl ketones Iridium Radical C—C coupling Amides