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Development of a deviation package method for low-cost robust optimization in compressor blade design

Chinese Journal of Aeronautics 2024年第4期37卷 166-180页

作者： Mingzhi LI Xianjun YU Dejun MENG guangfeng an Baojie LIU Research Institute of Aero-Engine Beihang UniversityBeijing 100191China National Key Laboratory of Science&Technology on Aero-Engine Aero-Thermodynamics Beihang UniversityBeijing 100191China AECC Shenyang Engine Research Institute Shenyang 110015China

Manufacture variations can greatly increase the performance variability of compressor blades. Current robust design optimization methods have a critical role in reducing the adverse impact of the variations, but can be affected by errors if the assumptions of the deviation models and distribution parameters are inaccurate. A new approach for robust design optimization without the employment of the deviation models is proposed. The deviation package method and the interval estimation method are exploited in this new approach. Simultaneously, a stratified strategy is used to reduce the computational cost and assure the optimization accuracy. The test case employed for this study is a typical transonic compressor blade profile, which resembles most of the manufacture features of modern compressor blades. A set of 96 newly manufactured blades was measured using a coordinate measurement machine to obtain the manufacture variations and produce a deviation package. The optimization results show that the scatter of the aerodynamic performance for the optimal robust design is 20% less than the baseline value. By comparing the optimization results obtained from the deviation package method with those obtained from widely-used methods employing the deviation model, the efficiency and accuracy of the deviation package method are demonstrated. Finally, the physical mechanisms that control the robustness of different designs were further investigated, and some statistical laws of robust design were extracted.

关键词： Manufacture variations Robust design optimization Compressor leading edge Aerodynamics Physical mechanism

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Lipid nanovehicles overcome barriers to systemic RNA delivery: Lipid components, fabrication methods, and rational design

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Acta Pharmaceutica Sinica B 2024年第2期14卷 579-601页

作者： Jing Yan Hao Zhang guangfeng Li Jiacan Su Yan Wei Can Xu Institute of Translational Medicine Shanghai UniversityShanghai 200444China Institute of Medicine Shanghai UniversityShanghai 200444China Department of Orthopedics Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200092China Department of Orthopedics Shanghai Zhongye HospitalShanghai 200941China Organoid Research Center Shanghai UniversityShanghai 200444China Department of Gastroenterology Changhai HospitalShanghai 200433China

Lipid nanovehicles are currently the most advanced vehicles used for RNA delivery,as demonstrated by the approval of patisiran for amyloidosis therapy in 2018.To illuminate the unique superiority of lipid nanovehicles in RNA delivery,in this review,we first introduce various RNA therapeutics,describe systemic delivery barriers,and explain the lipid components and methods used for lipid nanovehicle preparation.Then,we emphasize crucial advances in lipid nanovehicle design for overcoming barriers to systemic RNA delivery.Finally,the current status and challenges of lipid nanovehicle-based RNA therapeutics in clinical applications are also discussed.Our objective is to provide a comprehensive overview showing how to utilize lipid nanovehicles to overcome multiple barriers to systemic RNA delivery,inspiring the development of more high-performance RNA lipid nanovesicles in the future.

关键词： Lipid nanovehicles RNAtherapeutics Barriers to systemicRNA delivery Lipid components Fabricationmethods Lipid nanovehicledesign Extrahepatictissue targeting Organ tropism

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Application of machine learning models in groundwater quality assessment and prediction:progress and challenges

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Frontiers of Environmental Science & Engineering 2024年第3期18卷 25-55页

作者： Yanpeng Huang Chao Wang Yuanhao Wang guangfeng Lyu Sijie Lin Weijiang Liu Haobo Niu Qing Hu School of Environment Harbin Institute of TechnologyHarbin 150090China School of Environmental Science and Engineering Southern University of Science and TechnologyShenzhen 518055China Engineering Innovation Center of SUSTech(Beijing) Southern University of Science and TechnologyBeijing 100083China Technical Center for Soil Agriculture and Rural Ecology and EnvironmentMinistry of Ecology and EnvironmentBeijing 100012China Chinese Academy of Environmental Planning Beijing 100043China

Groundwater quality assessment and prediction(GQAP)is vital for protecting groundwater resources.Traditional GQAP methods can not adequately capture the complex relationships among attributes and have the disadvantage of being computationally demanding.Recently,the application of machine learning(ML)in GAQP(GQAPxML)has been widely studied due to ML’s reliability and efficiency.While many GQAPxML publications exist,a thorough review is missing.This review provides a comprehensive summary of the development of ML applications in the field of GQAP.First,the workflow of ML modeling is briefly introduced,as are data preparation,model development,model evaluation,and model application.Second,299 publications related to the topic are filtered,mainly through ML modeling.Subsequently,many aspects of GQAPxML,such as publication trends,the spatial distribution of study areas,the size of data sets,and ML algorithms,are discussed from a bibliometric perspective.In addition,we review in detail the well-established applications and recent findings for several subtopics,including groundwater quality assessment,groundwater quality modeling using groundwater quality parameters,groundwater quality spatial mapping,probability estimation of exceeding the groundwater quality threshold,groundwater quality temporal prediction,and the hybrid use of ML and physics-based models.Finally,the development of GQAPxML is explored from three perspectives:data collection and preprocessing,model building and evaluation,and the broadening of model applications.This review provides a reference for environmental scientists to better understand GQAPxML and promotes the development of innovative methods and improvements in modeling quality.

关键词： Groundwater quality assessment Groundwater quality prediction Machine learning Groundwater modeling

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Doping engineering of lithium-aluminum layered double hydroxides for high-efficiency lithium extraction from salt lake brines

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Nano Research 2024年第3期17卷 1646-1654页

作者： Lingjie Zhang Tingting Zhang Yunliang Zhao guangfeng Dong Shuaike Lv Songliang Ma Shaoxian Song Mildred Quintana School of Chemical and Environmental Engineering Wuhan Polytechnic UniversityWuhan 430023China School of Resources and Environmental Engineering Wuhan University of TechnologyWuhan 430070China Facultad de Ciencias Universidad Autonoma de San Luis PotosiAv.Parque Chapultepec 1570San Luis Potosi 78210Mexico Wuhan Clayene Technology Co. Ltd.Wuhan 430223China State Development Investment Xinjiang Lop Nur Potash Corporation Hami 839000China

Lithium-aluminum layered double hydroxides(LiAl-LDH)have been be successfully applied in commercial-scale for lithium extraction from salt lake brine,however,further advancement of their applications is hampered by suboptimal Li^(+)adsorption performance and ambiguous extraction process.Herein,a doping engineering strategy was developed to fabricate novel Zn^(2+)-doped LiAl-LDH(LiZnAl-LDH)with remarkable higher Li^(+)adsorption capacity(13.4 mg/g)and selectivity(separation factors of 213,834,171 for Li^(+)/K^(+),Li^(+)/Na^(+),Li^(+)/Mg^(2+),respectively),as well as lossless reusability in Luobupo brine compared to the pristine LiAl-LDH.Further,combining experiments and simulation calculations,it was revealed that the specific surface area,hydrophilic,and surface attraction for Li^(+)of LiZnAl-LDH were significantly improved,reducing the adsorption energy(Ead)and Gibbs free energy(ΔG),thus facilitating the transfer of Li^(+)from brine into interface followed by insertion into voids.Importantly,the intrinsic oxygen vacancies derived from Zn-doping depressed the diffusion energy barrier of Li^(+),which accelerated the diffusion process of Li^(+)in the internal bulk of LiZnAl-LDH.This work provides a general strategy to overcome the existing limitations of Li^(+)recovery and deepens the understanding of Li^(+)extraction on LiAl-LDH.

关键词： lithium extraction salt lake brines doping engineering lithium-aluminum layered double hydroxides density functional theory

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Method for utilizing PIV to investigate high curvature and acceleration boundary layer flows around the compressor blade leading edge

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Chinese Journal of Aeronautics 2022年第12期35卷 72-88页

作者： Baojie LIU Xiaobin XU Xianjun YU guangfeng an Research Institute of Aero-Engine Beihang UniversityBeijing 100083China National Key Laboratory of Science&Technology on Aero-Engine Aero-Thermodynamics Beihang UniversityBeijing 100083China School of Energy and Power Engineering Beihang UniversityBeijing 100083China

Particle Image Velocimetry(PIV)is a well-developed and contactless technique in experimental fluid mechanics,but the strong velocity gradient and streamline curvature near the wall substantially limits its accuracy improvement.This paper presents a data processing procedure combining conventional PIV and newly developed Mirror Interchange(MI)based Interface-PIV for the measurement of the boundary layer parameter development in the blade leading edge region.The synthetic particle images are used to analyze the measurement errors in the entire procedure.Overall,three types of errors,namely the errors caused by the Window Deformation Iterative Multigrid(WIDIM)algorithm,the discrete data interpolation and integration,and the wall offset uncertainty,comprise the main measurement error.Specifically,the errors due to the discrete data interpolation and integration and the WIDIM algorithm comprise the mean bias,which can be corrected through the error analysis method proposed in the present work.Meanwhile,the errors due to the WIDIM algorithm and the wall offset uncertainty contribute to the measurement uncertainty.Computational fluid dynamics-based synthetic particle flows were generated to verify the newly developed PIV data processing procedure and the corresponding error analysis method.Results showed that the data processing method could improve the accuracy of PIV measurements for boundary layer flows with high curvature and acceleration and even with significant flow separation bubbles.Finally,the data processing method is also applied in a PIV experiment to investigate the boundary layer flows around a compressor blade leading edge,and several credible boundary flow parameters were obtained.

关键词： Boundary layer measurement Compressor blade leading edge Mirror interchange method Particle image velocimetry Planar cascade experiment

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Exploration of acceptable operating range for a compression system in a double bypass engine

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中国航空学报:英文版 2023年第9期36卷 111-122页

作者： Ruoyu WANG Xianjun YU Baojie LIU guangfeng an Research Institute of Aero-Engine Beihang UniversityBeijing 102206China National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics Beijing 102206China

The variable cycle engine is distinguished by its highly adjustable compression system,whose aerodynamic characteristic is extremely complex.To explore the regulation range of a double bypass engine compression system,a multi-dimensional analysis method is developed,through which the coupling mechanism between the compressor component and the bypass is examined.The operation zones of the compressor components and the bypass system are proposed,and the operation range of the compression system is obtained by calculating the overlapping part of the operation zones.The results show that in the double bypass mode,there exists a minimum mode selector valve area and a minimum core driven fan stage stall margin that ensures a feasible bypass flow,the two parameters correspond to each other.Under the given fan and core driven fan stage conditions,the maximum value of the inner bypass ratio is restricted by the upper limit of the forward variable area bypass injector and the maximum Mach number in the total bypass,while the minimum value of the inner bypass ratio depends on the lower limit of the forward variable area bypass injector geometry and the system recirculation margin.The single bypass mode is a unique condition of the double bypass mode,as the operation zone of the compressor component degenerates from a two-dimensional surface to a straight line.There are multiple bypass states available in the single bypass mode,while the regulation range of the bypass ratio is jointly restricted by the operation range of the high pressure compressor and the aerodynamic boundary of the forward variable area bypass injector.

关键词： Compression system Coupling effect Matching mechanism Multi-dimensional method Operation range Variable cycle engine

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Numerical and experimental study of bleed impact in multistage axial compressors

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Chinese Journal of Aeronautics 2023年第2期36卷 1-16页

作者： Baojie LIU Xinwei ZHUANG guangfeng an Xianjun YU Research Institute of Aero-Engine Beihang UniversityBeijing 100191China National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics Beijing 100191China School of Energy and Power Engineering Beihang UniversityBeijing 100191China

In this study,the influence of inter-stage bleeding on the compressor performance and inter-stage flow field of a multistage axial compressor is investigated by both experimental and numerical methods.The experiment is conducted on a four-stage low-speed axial compressor,and a specific computational model is built to simulate the experiment environment accurately.To illuminate the fluid mechanisms of bleeding effect in detail,both the experiment and the simulation are carried out twice,i.e.,in the first time,the mass flow rate upstream the bleed location is constant under different bleed rate conditions;while in the second time,the mass flow rate downstream the bleed location is constant under different bleed rate conditions.The results demonstrate that inter-stage bleeding has little influence on upstream compressor characteristics,and affects the upstream flow field only in the rear half of the stator.The bleed effect on the downstream flow field is embodied in the variation of an incoming flow profile,an increase as the compressor inlet flow coefficient decreases.Therefore,such an effect is only significant on compressor characteristics at small flow coefficient conditions.In multistage compressors,the variation of compressor characteristics and flow field caused by inter-stage bleeding is the comprehensive result of the bleeding and the variation of the upstream working condition.In addition,the comparison between numerical and experimental results shows that the flow moves towards top half of span through the downstream rotor passage in the numerical simulation,whereas the trend of flow field variation with different bleed rates at the outlet of the downstream rotor and stator is the same with that at the inlet of the downstream rotor in the experiment,which means that the numerical method has overestimated the radial mixing intensity of the flow.

关键词： Compressor characteristics Inter-stage bleeding Low-speed compressor experiment Multistage axial compressor Spanwise mixing

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Using tandem blades to break loading limit of highly loaded axial compressors

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Chinese Journal of Aeronautics 2022年第4期35卷 165-175页

作者： Baojie LIU Chuanhai ZHANG guangfeng an Du FU Xianjun YU Research Institute of Aero-Engine Beihang UniversityBeijing 100083China School of Energy and Power Engineering Beihang UniversityBeijing 100083China Gree Electric Appliances Inc.of ZhuhaiZhuhai 519070China

It is confirmed that tandem-blade configurations have potential to enlarge the flow turning in two-dimension(2D) studies. However, the potential of tandem blades to enlarge the design space for highly loaded axial compressors was rarely investigated in open literatures. The present work aims to show the capability of tandem blades to break the loading limit of conventional blades for highly loaded compressors. The 2D models of the maximum static pressure rise derived in previous work were validated by a large amount experimental data, which showed a good agreement. An E parameter was defined to evaluate the stall margin of compressor based on the theoretical models, which indicated that the tandem blade was able to increase the loading limit of axial compressors. A single-blade stage with a loading coefficient of 0.46(based on the blade tip rotating speed) was designed as the baseline case under the guidance of the E parameter. A tandem-blade stage was then designed by ensuring that the velocity triangles were similar to the single-blade stage. The performances of both stages were investigated experimentally. The results showed that the maximum efficiency of the tandem-blade stage was 92.8%, 1% higher than the single;the stall margin increased from 16.9% to 22.3%. Besides, the maximum pressure rise of tandem rotors was beyond the loading limit of 2D single-blade cascades, which confirmed the potential of tandem blades to break the loading limit of axial compressors.

关键词： Cascades Highly loaded axial compressors Loading limit Single blades Tandem blades

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Analysis of the Exploration of Hematology Integration Education Model Guided by“Social Learning Theory”

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Journal of Clinical and Nursing Research 2024年第2期8卷 178-184页

作者： Li Jing guangfeng He Ji-Rui Tang Department of Hematology The Affiliated HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

Diseases of the blood system are highly complicated and involve many aspects.This article aimed to put forward the necessity of integrating quality and professional education,the necessity of learning logic,and the importance of establishing an integrated medical education model when teaching about blood system diseases.According to the requirements of the new medical science,this article puts forward the integration of an“online+offline+clinical”medical education mode based on the social learning theory and a learning evaluation mode based on medical literacy.The fundamental task of cultivating human beings into clinical medical talents with professional ethics,independent learning abilities,interpersonal communication abilities,complex problem-solving abilities,innovative consciousness,and critical thinking was implemented.This article aims to propose an improved construction plan to create a new and improved teaching system in medicine.

关键词： Hematology Social learning Fuse New medicine

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习近平文化思想的理论创新及重大意义

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华东师范大学学报（哲学社会科学版） 2024年第3期56卷 11-18,175页

作者：刘光峰上海财经大学马克思主义学院上海200433

习近平文化思想的理论创新早已散见于习近平总书记围绕建设什么样的新时代文化、如何建设新时代文化所作的系列重要讲话、指示、批示及著作中。在文化领导权、文化阵地、文化自信、文化人才培养、网络文化建设、党的文化宣传、文化事业... 详细信息

习近平文化思想的理论创新早已散见于习近平总书记围绕建设什么样的新时代文化、如何建设新时代文化所作的系列重要讲话、指示、批示及著作中。在文化领导权、文化阵地、文化自信、文化人才培养、网络文化建设、党的文化宣传、文化事业与文化产业发展、铸牢中华民族共同体意识等诸多领域,习近平文化思想都有重大创新,提出了一系列富有中国特色和时代灵魂的新见解新理念。习近平文化思想的形成,标志着我们党对于党内文化、社会主义文化及人类文化认识达到新高度,开辟了文化认知新境界,对于塑造党的政党形象、巩固党执政的思想基础、推动中华民族伟大复兴、构建人类命运共同体具有重要的里程碑意义。

关键词：习近平文化思想新观点新境界

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