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Asian Agricultural Research 2024年第3期16卷 18-24页

作者： Zhiguo SUN Li GAO Yuanpeng SUN guangchao cao Xinying ZHOU Xiaoqiang LI Hubei University of Science and Technology Xianning 437100China Academy of Plateau Science and Sustainability of People s Government of Qinghai Province&Beijing Normal University Xining 810008China Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of SciencesBeijing 100044China

In the new era,there is an urgent need to further promote pairing assistance to Tibet,promote the simultaneous construction of a strong agriculture in Tibet and the China's Mainland,and compose a Chinese-style modernization.Southern Tibet,located in the southeastern part of the Tibet Autonomous Region,includes Shannan City and Nyingchi City,is a region assisted by four provincial partners including Hubei Province.This paper introduces the agricultural environment in southern Tibet,studies its agricultural characteristics,and analyzes the main issues of its pairing assistance.Taking forging the strong consciousness of the Chinese national community as the main line,the paper explores strategies for promoting agricultural high-quality development in southern Tibet through pairing assistance to Tibet from the perspective of agricultural power,and proposes some strategies,such as inheriting agricultural cultural heritage,promoting the upgrading of modern seed industry,enhancing the characteristic advantages of highland barley(naked barley)and animal husbandry industries,and developing edible fungi and cold water fish industries.

关键词： Pairing assistance to Tibet Southern Tibet Shannan City Nyingchi City Agricultural high-quality development Agricultural power

Normalization cancer immunotherapy: blocking Siglec-15!

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Signal Transduction and Targeted Therapy 2019年第1期4卷 576-577页

作者： guangchao cao Zhiqiang Xiao Zhinan Yin The First Affiliated Hospital Biomedical Translational Research InstituteSchool of PharmacyJinan UniversityGuangzhouChina The Tenth People’s Hospital of Tongji University ShanghaiChina

In a recent paper published in Nature medicine,Wang,J.,et al.identified Siglec-15 as a new candidate responsible for adaptive immune resistance and a potential target for normalization cancer immunotherapy.1 Cancer cells can develop various mechanisms to evade tumor-specific and non-specific attacks in the TME of solid tumors.2 Thus,systemic activation of immune systems or even increasing tumor-specific T cells in the peripheral does not necessarily lead to tumor regression.In fact,almost all the known strategies adopted by cancer for immune escape are also used for maintaining systemic homeostasis.

关键词： immunotherapy cancer al.

高寒山地生态修复方式对土壤颗粒碳氮分配的影响

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生态科学 2024年第1期43卷 10-18页

作者：汉光昭曹广超曹生奎冶文倩程国青海师范大学地理科学学院西宁810008 青海省自然地理与环境过程重点实验室西宁810008 青藏高原地表过程与生态保育教育部重点实验室西宁810008 青海省人民政府—北京师范大学高原与可持续发展研究院西宁810008

通过探讨草地和林地两种修复方式下不同粒径土壤颗粒有机碳和全氮的分配规律,以期能够为高寒山地生态修复措施对土壤颗粒碳氮的影响提供参考。以空间序列代替时间序列的方法,分别选取不同恢复年限的草地和林地作为研究对象,管理方式分... 详细信息

通过探讨草地和林地两种修复方式下不同粒径土壤颗粒有机碳和全氮的分配规律,以期能够为高寒山地生态修复措施对土壤颗粒碳氮的影响提供参考。以空间序列代替时间序列的方法,分别选取不同恢复年限的草地和林地作为研究对象,管理方式分别为仅在生长季封育和常年封育。对生长季野外现场采集的土壤样品在实验室采用离心法对土壤颗粒进行分级,分为砂粒(2000—50μm)、粉粒(50—2μm)和粘粒(<2μm),以此分析不同粒径土壤颗粒中有机碳和全氮的分配规律。结果显示:1)不同修复年限草地和林地土壤颗粒有机碳和全氮的分配主体分别为砂粒和粉粒,草地和林地土壤颗粒有机碳在砂粒中的分配比例分别为57.36%和46.46%,全氮在粉粒中的分配比例分别为44.79%和42.55%。2)两种修复用地三种粒径土壤颗粒碳氮分配比例均与其组分含量呈正相关关系,砂粒的碳氮分配比例主要受地下生物量和土壤总孔隙度影响,粘粒和粉粒碳氮分配比例主要受容重和pH的影响。本研究区植树造林的修复方式对土壤颗粒碳氮的分配影响更为明显。

关键词：土壤颗粒有机碳全氮生态修复高寒山地

祁连山南坡微地形下典型生态系统土壤蓄水能力差异

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水土保持研究 2024年第1期31卷 159-167,177页

作者：袁杰曹广超曹生奎袁有靖张虔蒲妮青海师范大学.青藏高原地表过程与生态保育教育部重点实验室西宁810008 青海师范大学.地理科学学院.青海省自然地理与环境过程重点实验室西宁810008 青海省人民政府—北京师范大学高原科学与可持续发展研究院西宁810008 青海省地质环境调查院西宁810008

[目的]探讨祁连山地区微地形形态下典型生态系统土壤蓄水能力差异性,为该区进一步提高水源涵养能力提供参考。[方法]以微地形不同坡向青海云杉和高山草地为研究对象,采取野外采样和室内试验分析相结合的方法,研究不同坡向对典型生态系... 详细信息

[目的]探讨祁连山地区微地形形态下典型生态系统土壤蓄水能力差异性,为该区进一步提高水源涵养能力提供参考。[方法]以微地形不同坡向青海云杉和高山草地为研究对象,采取野外采样和室内试验分析相结合的方法,研究不同坡向对典型生态系统土壤蓄水能力的影响。[结果](1)微地形高山草地所在阳坡区域,土壤水分贮存量随坡位上升逐渐呈减少趋势,坡中上(PZS)为土壤水分贮存量最低的坡位;坡位对土壤饱和蓄水量影响较小。(2)坡位显著影响着阴坡青海云杉土壤水分贮存量,土壤贮水量沿坡位上升呈增加趋势,坡顶处(PSD)土壤水分贮存量最高;坡位对青海云杉土壤潜在蓄水能力影响显著,坡中和坡中上土壤潜在蓄水能力最强。(3)两类典型生态系统土壤蓄水能力存在显著差异,高山草地(阳坡)土壤实际蓄水能力在不同坡位均高于青海云杉,青海云杉(阴坡)土壤潜在蓄水能力在坡位和土层尺度均显著大于高山草地(阳坡)。[结论]研究区微地形坡中上至坡顶段是该区保水增蓄的重点区域,坡中上以下区域是两类生态系统土壤蓄水能力核心区域,应继续保护。

关键词：微地形典型生态系统土壤蓄水差异分析

2000—2020年青海湖流域植被降水利用效率时空变化

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生态学报 2024年第8期44卷 3423-3439页

作者：赵浩然曹生奎曹广超李文斌陈链璇侯瑶芳青海师范大学地理科学学院青海省自然地理与环境过程重点实验室西宁810008 青海师范大学青藏高原地表过程与生态保育教育部重点实验室西宁810008 青海省人民政府-北京师范大学高原科学与可持续发展研究院西宁810008

植被降水利用效率(PUE)是评价植被生产力对降水量时空动态响应特征的重要指标。以年净初级生产力(NPP)数据、年降水量数据为基础,利用地理信息系统(GIS)和遥感(RS)技术,计算并研究了2000—2020年青海湖流域植被降水利用效率时空分布格... 详细信息

植被降水利用效率(PUE)是评价植被生产力对降水量时空动态响应特征的重要指标。以年净初级生产力(NPP)数据、年降水量数据为基础,利用地理信息系统(GIS)和遥感(RS)技术,计算并研究了2000—2020年青海湖流域植被降水利用效率时空分布格局及其地形效应,结合年均气温、年均地表温湿度、年生长季光合有效辐射吸收系数和年植被覆盖度等数据,探讨了PUE与各因子间的相关关系。结果表明:(1)青海湖流域单位像元(1 km^(2))PUE平均值在0.4—0.7 gC m^(-2)mm^(-1)间变化,平均为0.54 gC m^(-2)mm^(-1),且在年际间无显著变化趋势(R^(2)=0.05,P≥0.05)。在空间上,青海湖流域多年PUE平均值环湖呈现不均匀分布,除青海湖东岸外,PUE值随湖面距离增大呈减小趋势;其高值区主要集中分布在青海湖西岸和南岸的半环区;年PUE变化趋势的斜率值为-0.05—0.04 gC m^(-2)mm^(-1)a-1,其中显著变化的区域占流域面积的29.63%。(2)青海湖流域多年PUE平均值在海拔效应和坡度坡向两种不同微地形效应下表现出明显的差异。海拔每升高50 m,PUE值将减少0.02 gC m^(-2)mm^(-1);随坡度增加,PUE值呈降低趋势,平坡至险坡(>45°)的变化范围为0.3—0.61 gC m^(-2)mm^(-1);不同坡向PUE值表现为由东北坡向西南坡递减,范围为0.52—0.56 gC m^(-2)mm^(-1)。(3)在空间上,青海湖流域PUE值与地表温度、光合有效辐射吸收系数、植被覆盖度和叶面积指数相关性较为明显。沿海拔梯度,空气温度和地表温度与PUE呈极显著正相关(R^(2)=0.94,P<0.01;R^(2)=0.98,P<0.01),光合有效辐射吸收系数、植被覆盖度和叶面积指数与PUE显著正相关(R^(2)=0.89,P<0.05;R^(2)=0.90,P<0.05;R^(2)=0.86,P<0.05),地表土壤湿度与PUE无显著相关性(R^(2)=0.16,P≥0.05)。评估了青海湖流域植被降水利用效率的特征及其与各因子间的相关关系,明确了植被对降水的利用能力及其耗水特性,可为青海湖流域植被保护和国家公园建设提供理论参考。

关键词：降水利用效率时空特征相关关系青海湖流域

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基于InVEST模型的共和县生境质量时空变化及驱动因素

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干旱区研究 2024年第2期41卷 314-325页

作者：严莉曹广超康利刚刘梦琳叶得力青海师范大学地理科学学院青海省自然地理与环境过程重点实验室青海西宁810008 青海师范大学青藏高原地表过程与生态保育教育部重点实验室青海西宁810008 青海省人民政府-北京师范大学高原科学与可持续发展研究院青海西宁810008 青海黄河上游水电开发有限责任公司高原能源产业与生态研究中心青海西宁810008

在新型城镇化背景下,青海省共和县作为兰西城市群建设的关键节点和典型的荒漠生态脆弱区,其经济和生态的协调发展对建设海南州可持续发展议程创新示范区具有重要意义。本研究基于2000年、2010年、2020年三期土地利用数据,利用InVEST模型... 详细信息

在新型城镇化背景下,青海省共和县作为兰西城市群建设的关键节点和典型的荒漠生态脆弱区,其经济和生态的协调发展对建设海南州可持续发展议程创新示范区具有重要意义。本研究基于2000年、2010年、2020年三期土地利用数据,利用InVEST模型,对2000—2020年共和县生境质量时空分布及效应变化特征进行探究,进而对生境质量的影响因子及其作用进行地理探测器和局部空间回归。结果表明:(1)2000—2020年共和县生境质量整体呈上升趋势,生境质量均值分别为0.612(2000年)、0.626(2010年)、0.627(2020年),生境质量空间分布存在明显的区域差异,空间格局上呈现北高南低的态势。(2)影响共和县生境质量的主驱动因子为年平均气温(TEM)和归一化植被指数(NDVI),因子间的交互作用对生境质量空间分异的影响大于单一因子,TEM与香农均匀度指数(SHEI)、香农多样性指数(SHDI)交互作用强烈。(3)TEM对生境质量呈负向效应,负向影响区域主要集中在共和北部与东部地区;NDVI呈正向效应,正向影响区域主要集中在共和中部与南部地区;国民生产总值(GDP)对生境质量的正向效应较2000年上升了30%,塔拉滩光伏促进了共和县生态产业协同发展。研究结果可为干旱区推动地方经济建设和生态环境保护提供科学的决策依据。

关键词： InVEST模型生境质量地理探测器地理加权回归(GWR) 共和县青海省

Metabolic Control ofγδT Cell Function

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Infectious Microbes & Diseases 2021年第3期3卷 142-148页

作者： Ziyu Meng guangchao cao Quanli Yang Hengwen Yang Jianlei Hao Zhinan Yin NHC Key Laboratory of Hormones and Development Tianjin Key Laboratory of Metabolic DiseasesTianjin Medical University Chu Hsien-I Memorial Hospital&Tianjin Institute of EndocrinologyTianjin Medical UniversityTianjinChina Zhuhai Institute of Translational Medicine Zhuhai People's Hospital Affiliated with Jinan UniversityJinan UniversityZhuhaiGuangdongChina The Biomedical Translational Research Institute Faculty of Medical ScienceJinan UniversityGuangzhouGuangdongChina.

Metabolic change is associated with cell activities,such as signal transduction,cell differentiation,and cell cycle.In the pathogenesis of autoimmune diseases,abnormal activation of T cells is often accompanied by changes in their metabolism.Conversely,the changes of metabolites can also regulate the proliferation,differentiation,and function of T cells.As a bridge between innate and adaptive immune responses,γδT cells have unique biological characteristics and functions.However,the immunometabolic mechanism ofγδT cells has been a novel field for research in recent years.In this review,we summarize the influence of metabolic pathways and nutrients onγδT cell function,and metabolic features ofγδT cell subsets,which may provide new insights in interventions targetingγδT cells in disease control.

关键词： γδT cells immunometabolism glucose fatty acid amino acid vitamins plant extract

Soil microbial community diversity and distribution characteristics under three vegetation types in the Qilian Mountains, China

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Journal of Arid Land 2023年第3期15卷 359-376页

作者： TONG Shan cao guangchao ZHANG Zhuo ZHANG Jinhu YAN Xin Key Laboratory of Tibetan Plateau Land Surface Processes and Ecological Conservation(Ministry of Education) Qinghai Normal UniversityXining 810008China Qinghai Province Key Laboratory of Physical Geography and Environmental Process College of Geographical ScienceQinghai Normal UniversityXining 810008China Academy of Plateau Science and Sustainability People's Government of Qinghai Province and Beijing Normal UniversityXining 810008China

Qilian Mountains in Northwest China is a significant ecological security barrier due to its distinctive geographic setting,which has significant biological resource and gene pool.In order to assess the soil quality and ecosystem health in this area,we identified the structural characteristics and functional groups of soil microbial communities.This study focused on Amidongsuo,a typical watershed of the Qilian Mountains,and researched the vertical distribution and dominant populations of soil microorganisms in different habitats,and the relationship between soil microorganisms and environmental factors.Soil microorganisms from three grassland plots,five shrubland plots,and five forest plots in Amidongsuo were studied using high-throughput sequencing.The Venn diagram showed that the types of bacteria were fewer than those of fungi in Amidongsuo.Soil bacteria Acidobacteriota,Proteobacteria,and Methylomirabilota as well as fungi Basidiomycota,Ascomycota,and Mortierellomycota played dominant roles in Amidongsuo,according to the LEfSe(linear discriminant analysis(LDA)effect size)and community structure analyses.According to the ANOSIM(analysis of similarities)result,for both bacteria and fungi,R values of grassland and shrubland were small(R^(2)=0.045 and R^(2)=0.256,respectively),indicating little difference between these two ecosystems.RDA(redundancy analysis)showed a closer relationship between soil nutrients and fungi,and a gradually decreasing correlation between soil nutrients and microorganisms with increasing soil depth.Bacteria were mainly affected by pH,nitrogen(N),and potassium(K),while fungi were mainly affected by K.Overall,fungi had more effect on soil quality than bacteria.Therefore,adjustment of soil K content might improve the soil environment of Amidongsuo in the Qilian Mountains.

关键词： fungi bacteria diversity soil nutrient Qilian Mountains

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压电式超声雾化降尘系统设计及其试验研究

机械科学与技术 2024年第2期43卷 258-264页

作者：曹帅韩光超徐林红江进国卢禄华彭清围中国地质大学(武汉)机械与电子信息学院武汉430070 厦门三烨清洁科技股份有限公司福建厦门361102 中国地质大学深圳研究院广东深圳518057

通过传送带传送物料是散料工业运输的主要方式,对运输过程中产生的粉尘进行治理是散料工业运输亟需解决的问题,目前应用比较多的方法为雾化降尘法。为了提升雾化降尘的效果,设计了一种30 kHz喇叭型压电式超声雾化装置和配套的雾化降尘... 详细信息

通过传送带传送物料是散料工业运输的主要方式,对运输过程中产生的粉尘进行治理是散料工业运输亟需解决的问题,目前应用比较多的方法为雾化降尘法。为了提升雾化降尘的效果,设计了一种30 kHz喇叭型压电式超声雾化装置和配套的雾化降尘试验系统,并采用单因素试验研究入口水流量、风速、粉尘种类、颗粒直径、喷嘴安装角度等工艺参数对雾化降尘效率的影响规律。结果表明,当入口水流量为30 L/h时,对煤粉粉尘降尘效率为75.9%;当风速为2.1 m/s时,对煤粉粉尘降尘效率为61.1%;相比较于煤粉和沙子,黄土的降尘效率略高;该喷嘴对粒径为107~180μm范围内的煤粉粉尘降尘效率最高为73.9%;当喷嘴安装角度为0时,对煤粉粉尘降尘效率最高为81%。

关键词：超声振动雾化降尘散料降尘效率

Spatio-temporal variation of water conservation and its impact factors on the southern slope of Qilian Mountains

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Regional Sustainability 2023年第1期4卷 54-67页

作者： WEI Xingtao Oliver Valentine EBOY cao guangchao XU Lu Faculty of Social Sciences and Humanities Universiti Malaysia SabahKota Kinabalu88400Malaysia Qinghai Province Key Laboratory of Physical Geography and Environmental Process Xining810008China

The ecology of Qilian Mountains has been seriously threatened by uncontrolled grazing and wasteland reclamation. This study examined the ecological changes on the southern slope of Qilian Mountains in China from the perspective of water conservation by classifying different clusters of water conservation functional areas to efficiently use limited human resources to tackle the water conservation protection problem. In this study, we used Integrate Valuation of Ecosystem Services and Tradeoffs(InVEST) model to estimate water conservation and analyzed the factors that influence the function. The results of this study include:(1) from 2000 to 2015, the water conservation of the southern slope of Qilian Mountains generally showed an increasing trend, and the total water conservation in 2015 increased by 42.18% compared with that in 2000.(2) Rainfall, fractional vegetation cover(FVC), and evapotranspiration have the most significant influence on the water conservation of the study area. Among them, water conservation is positively correlated with rainfall and FVC(P<0.05) and negatively correlated with evapotranspiration(P<0.05).(3) The importance level of water conservation functional areas gradually increases from northwest to southeast, and the region surrounding Menyuan Hui Autonomous County in the southeast of the southern slope of Qilian Mountains is the core water conservation functional area. And(4) the study area was divided into five clusters(Cluster Ⅰ–Cluster Ⅴ) of water conservation, with the areas of Clusters Ⅰ through Ⅴ accounting for 0.58%, 13.74%, 41.23%, 32.43%, and 12.01% of the whole study area, respectively.

关键词： Water conservation InVEST model The southern slope of Qilian Mountains Water balance principle Evapotranspiration Analytic Hierarchy Process(AHP)