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Journal of Iron and Steel Research International 2016年第10期23卷 1086-1095页

作者： Feng LU guang-ping cheng Feng CHAI Tao PAN Zhong-ran SHI Hang SU Cai-fu YANG School of Material Science and Engineering Anhui University of Technology Department of Structural Steel Central Iron and Steel Research Institute

The combined effects of martensite-austenite（MA）constituent and pearlite colony on cleavage crack initiation in the simulated coarse-grained heat-affected zone（CGHAZ）of V-N-Ti microalloyed offshore platform steel under different heat inputs were *** results of welding simulation,instrumented impact test,and quantitative analysis indicated that the size of the MA constituent decreased with the increase in cooling time,and by contrast,the size of the pearlite colony *** to Griffith theory,the critical sizes of cleavage microcracks were *** the increase of cooling time,the calculated microcrack size could be characterized by the size of the MA constituent first,and then fitted with the size of the pearlite ***,the calculated microcrack size variation was opposite to the microcrack initiation *** phenomenon is probably due to the combined effects of the MA constituent and pearlite colony with increasing the cooling time of the specimen′s temperature from800 to 500 ℃.

关键词： simulated coarse-grained heat-affected zone martensite-austenite constituent pearlite colony cleavage fracture V-N-Ti microaltoying

Effect of calcium addition on microstructure and texture modification of Mg rolled sheets

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Transactions of Nonferrous Metals Society of China 2015年第9期25卷 2875-2883页

作者：丁汉林张鹏程广萍 Shigeharu KAMADO 安徽工业大学材料科学与工程学院马鞍山243002 上海交通大学轻合金精密成型国家工程研究中心上海200030 Department of Mechanical Engineering Nagaoka University of Technology

The mechanical properties and texture of AM60（Mg-6.0Al-0.3Mn,mass fraction %） and ZXM200（Mg-1.6Zn-0.5Ca-0.2Mn） Mg alloys subjected to multi-pass hot rolling were *** finer recrystallized grains usually exhibit particular preferred orientations and then alter the total texture feature of rolled *** solid solution into Mg matrix serves to the formation of texture component with c-axis rotated away from normal direction towards transverse direction and then weakens the overall texture intensity,resulting in a similar anisotropic characteristic to RE-containing Mg alloys.

关键词： Mg sheets hot rolling dynamic recrystallization Ca addition texture weakening

Human-induced pluripotent stem cell-derived neural stem cell exosomes improve blood-brain barrier function after intracerebral hemorrhage by activating astrocytes via PI3K/AKT/MCP-1 axis

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Neural Regeneration Research 2025年第2期20卷 518-532页

作者： Conglin Wang Fangyuan cheng Zhaoli Han Bo Yan Pan Liao Zhenyu Yin Xintong Ge Dai Li Rongrong Zhong Qiang Liu Fanglian Chen ping Lei Department of Geriatrics Tianjin Medical University General HospitalTianjinChina School of Medicine Nankai UniversityTianjinChina Tianjin Neurological Institute TianjinChina

Cerebral edema caused by blood-brain barrier injury after intracerebral hemorrhage is an important factor leading to poor ***-induced pluripotent stem cell-derived neural stem cell exosomes(hiPSC-NSC-Exos)have shown potential for brain injury repair in central nervous system *** this study,we explored the impact of hiPSC-NSC-Exos on blood-brain barrier preservation and the underlying *** results indicated that intranasal delivery of hiPSC-NSC-Exos mitigated neurological deficits,enhanced blood-brain barrier integrity,and reduced leukocyte infiltration in a mouse model of intracerebral ***,hiPSC-NSC-Exos decreased immune cell infiltration,activated astrocytes,and decreased the secretion of inflammatory cytokines like monocyte chemoattractant protein-1,macrophage inflammatory protein-1α,and tumor necrosis factor-αpost-intracerebral hemorrhage,thereby improving the inflammatory *** sequencing indicated that hiPSC-NSC-Exo activated the PI3K/AKT signaling pathway in astrocytes and decreased monocyte chemoattractant protein-1 secretion,thereby improving blood-brain barrier *** with the PI3K/AKT inhibitor LY294002 or the monocyte chemoattractant protein-1 neutralizing agent C1142 abolished these *** summary,our findings suggest that hiPSC-NSC-Exos maintains blood-brain barrier integrity,in part by downregulating monocyte chemoattractant protein-1 secretion through activation of the PI3K/AKT signaling pathway in astrocytes.

关键词： AKT astrocyte blood-brain barrier cerebral edema exosomes human-induced pluripotent stem cells intracerebral hemorrhage neural stem cells neuroinflammation PI3K

Fanlian Huazhuo formula:A promising therapeutic approach for metabolic associated steatotic liver disease

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World Journal of Gastroenterology 2025年第1期31卷 167-171页

作者： Chun-Han cheng Wen-Rui Hao Tzu-Hurng cheng Department of Medical Education Linkou Chang Gung Memorial HospitalTaoyuan 33305Taiwan Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561Taiwan Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002Taiwan Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404328Taiwan

This article reviews the study,“Fanlian huazhuo formula alleviates high-fat-dietinduced nonalcoholic fatty liver disease by modulating autophagy and lipid synthesis signaling pathway”published in the World Journal of *** study explores the therapeutic potential of Fanlian Huazhuo formula(FLHZF)in treating metabolic-associated steatotic liver disease(MASLD),demonstrating that FLHZF reduces lipid accumulation,oxidative stress,and liver injury in MASLD models by modulating key signaling pathways involved in lipid metabolism and *** editorial emphasizes the potential of FLHZF as a treatment for MASLD and calls for further research to verify its clinical efficacy.

关键词： Fanlian Huazhuo formula Metabolic associated steatotic liver disease Autophagy Lipid metabolism Oxidative stress

CAUSES AND CONTROL COUNTERMEASURES OF EUTROPHICATION IN CHAOHU LAKE, CHINA

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Chinese Geographical Science 2005年第4期15卷 348-354页

作者： SHANG guang-ping SHANG Jin-cheng College of Urban and Environmental Sciences Northeast Normal University Changchun 130024 P. R. China Hefei Environmental Monitoring Center Hefei 230031 P. R. China

Chaohu Lake, located in the central Anhui Province, is one of the five largest fresh lakes in China. Now it is one of the three most eutrophication lakes in China. The deterioration of its water quality has influenced the sustainable development of society, economy and environment of Hefei City, the capital of Anhui Province. A series of measures have been carried out to control its eutrophication, but it is still serious. On the basis of the lake water quality data from 1984 to 2003, the causes of the eutrophication of Chaohu Lake are analyzed. Studies indicated that the suitable natural conditions and human activities played a crucial role in the process of the eutrophication of Chaohu Lake. A great amount of industrial, agricultural and domestic sewage discharged into the lake is the main cause of eutrophication in the lake. Land use, soil erosion and shoreline collapse destroyed the watershed eco-environment and the terrestrial ecosystem of Chaohu Lake. And the building of Yuxi Gate extends the sluggish of the nutritious substance and speeds up the process of the eutrophication. From the view of systematic engineering and watershed ecology, a series of the countermeasures have been put forward to control the eutrophication.

关键词： causes of eutrophication eutrophication control non-engineering measures watershed management Chaohu Lake

MnSOD基因转染对SGC79001胃癌细胞增殖的影响

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复旦学报（医学版） 2004年第1期31卷 19-23,31页

作者：陈坚林庚金唐峰朱虹光钱立平程建刘珊林复旦大学附属华山医院消化科上海200040 附属华山医院病理科上海200040 复旦大学上海医学院生物化学系上海200032

目的观察改变胞内MnSOD基因表达水平对SGC7901胃癌细胞增殖的影响。方法采用电穿孔方法将反义和正义MhSOD cDNA真核表达载体pHβA-SOD(-)/pHβA-SOD(+)转染SGC7901胃癌细胞,400mg/LG418筛选稳定表达克隆并用RT-PCR及Western杂交法鉴... 详细信息

目的观察改变胞内MnSOD基因表达水平对SGC7901胃癌细胞增殖的影响。方法采用电穿孔方法将反义和正义MhSOD cDNA真核表达载体pHβA-SOD(-)/pHβA-SOD(+)转染SGC7901胃癌细胞,400mg/LG418筛选稳定表达克隆并用RT-PCR及Western杂交法鉴定后扩大培养。用pHβA空质粒转染作为对照。放射免疫法检测正义、反义及空载SGC7901胃癌细胞株内的铜锌超氧化物歧化酶(CuZnSOD,SOD1)蛋白含量。分别用直接细胞计数法、四唑蓝(MTT)比色法、平皿克隆形成率试验及裸鼠移植瘤模型测定3组细胞在体外、体内的增殖活性。结果与空载组(Vector—7901)相比,转染正义质粒的MnSOD-7901胃癌细胞呈现抑增殖效应:(1)生长曲线示增殖速度减慢;(2)在平皿上的集落形成能力下降;(3)在裸鼠体内的成瘤性明显受抑制。转染反义质粒的MnSOD-AS7901胃癌细胞则出现促增殖效应:(1)生长曲线示增殖速度加快;(2)在平皿上的集落形成率上升;(3)裸鼠移植瘤生长加速。结论通过基因转染提高胞内MnSOD的表达可抑制胃癌细胞的增殖,MnSOD可能是胃癌基因治疗的一个新靶点。

关键词： MnSOD 基因转染 SGC79001 胃癌癌细胞增殖基因表达超氧化物歧化酶

Insertion of Supramolecular Segments into Covalently Crosslinked Polyurethane Networks towards the Fabrication of Recyclable Elastomers

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Chinese Journal of Polymer Science 2022年第3期40卷 321-330,I0009页

作者： Lu-ping Wang Ming-guang Zhang Jing-cheng Hao Xu Wang National Engineering Research Center for Colloidal Materials School of Chemistry and Chemical EngineeringShandong UniversityJinan 250100China Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education School of Chemistry and Chemical EngineeringShandong UniversityJinan 250100China

Thermoset plastics have become one of the most important chemical products in the world. The consequent problem is that although the thermosets possess excellent performance in mechanical strength, they cannot be reprocessed because of the internal permanent network structures. Optimizing the molecular design of thermosets is one of the most feasible ways to improve their recyclability. Here we present a facile and robust strategy to engineer the reprocessability of thermoset polyurethanes without compromising their mechanical toughness and chemical resistance via adding supramolecular additives during the polymer synthesis process. By using a multiple hydrogen bonding moiety as the model supramolecular additive, we demonstrate that the mechanical properties, recyclability, and chemical resistance of the crosslinked polyurethanes can be precisely controlled by adjusting the contents of the supramolecular additive. Systematic studies on the relations between molecular design and material properties are performed, and the optimized polyurethane network with a moderate amount of the supramolecular additive achieves the right balance between the robustness and recyclability. This work provides a cost-effective and practical way to chemically engineer thermoset plastics, aiming to enable the recycling of mechanically tough and chemically stable polymer materials.

关键词： Thermoset plastics Recyclability Polyurethane Supramolecular additives Chemical resistance

Anisotropic diffusion of volatile pollutants at air-water interface

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Water Science and Engineering 2013年第2期6卷 153-163页

作者： Li-ping CHEN Jing-tao cheng guang-fa DENG College of Urban Construction and Safety Engineering Nanjing University of Technology Jiangsu Frontier Electric Technology Co. Ltd.

The volatile pollutants that spill into natural waters cause water pollution. Air pollution arises from the water pollution because of volatilization. Mass exchange caused by turbulent fluctuation is stronger in the direction normal to the air-water interface than in other directions due to the large density difference between water and air. In order to explore the characteristics of anisotropic diffusion of the volatile pollutants at the air-water interface, the relationship between velocity gradient and mass transfer rate was established to calculate the turbulent mass diffusivity. A second-order accurate smooth transition differencing scheme （STDS） was proposed to guarantee the boundedness for the flow and mass transfer at the air-water interface. Simulations and experiments were performed to study the trichloroethylene （C2HC13） release. By comparing the anisotropic coupling diffusion model, isotropic coupling diffusion model, and non-coupling diffusion model, the features of the transport of volatile pollutants at the air-water interface were determined. The results show that the anisotropic coupling diffusion model is more accurate than the isotropic coupling diffusion model and non-coupling diffusion model. Mass transfer significantly increases with the increase of the air-water relative velocity at a low relative velocity. However, at a higher relative velocity, an increase in the relative velocity has no effect on mass transfer.

关键词： volatile pollutant," interfacial mass transfer anisotropic diffusion STDS anisotropic coupling diffusion model

Ground Rotation Band of a 6-Boson System

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Chinese Physics Letters 1999年第12期16卷 891-893页

作者： BAO cheng-guang HUI ping HE Yan-zhang Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion AcceleratorLanzhou 730000 Department of Physics Zhongshan UniversityGuangzhou 510275 Department of Physics Educational College of GuangdongGuangzhou 510310

A 6-boson system has been qualitatively studied based on symmetry consideration. Emphasis is placed on the ground rotation band based on the octahedron structure. In this band the L = 1 , 2, and 3 states are found to ... 详细信息

关键词： structure. state. rotation

Molecular simulation study of the microstructures and properties of pyridinium ionic liquid[HPy][BF_(4)]mixed with acetonitrile

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原子与分子物理学报 2025年第4期42卷 27-32页

作者： XU Jian-Qiang MA Zhao-Peng cheng Si LIU Zhi-Cong ZHU guang-Lai Department of Physics School of Physics and Electronic InformationAnhui Normal UniversityWuhu 241002China

The microstructures and thermodynamic properties of mixed systems comprising pyridinium ionic liquid[HPy][BF_(4)]and acetonitrile at different mole fractions were studied using molecular dynamics simulation in this *** following properties were determined:density,self-diffusion coefficient,excess molar volume,and radial distribution *** results show that with an increase in the mole fraction of[HPy][BF_(4)],the self-diffusion coefficient ***,the excess molar volume initially decreases,reaches a minimum,and then *** rules of radial distribution functions(RDFs)of characteristic atoms are *** increasing the mole fraction of[HPy][BF_(4)],the first peak of the RDFs of HA1-F decreases,while that of CT6-CT6 rises at first and then *** indicates that the solvent molecules affect the polar and non-polar regions of[HPy][BF_(4)]differently.

关键词： Pyridinium ionic liquids Thermodynamic properties Molecular dynamics simulation Radial distribution functions