检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

硫酸盐对淡水浮游藻类群落结构的影响研究

环境科学 2009年第8期30卷 2253-2258页

作者：钟远樊娟刘春光庄源益南开大学环境科学与工程学院环境污染过程与基准教育部重点实验室天津300071 天津城市建设学院天津300084

为了解硫酸盐含量增加对富营养化淡水水体藻类生长及群落演替的影响,对天津市某景观水体藻类进行了室内模拟试验研究.按硫酸盐投加方式分设对照组(G0)、逐步投加组(G1)和一次性投加组(G2).结果表明,向水中投加一定浓度硫酸盐可以抑制原... 详细信息

为了解硫酸盐含量增加对富营养化淡水水体藻类生长及群落演替的影响,对天津市某景观水体藻类进行了室内模拟试验研究.按硫酸盐投加方式分设对照组(G0)、逐步投加组(G1)和一次性投加组(G2).结果表明,向水中投加一定浓度硫酸盐可以抑制原有蓝藻和硅藻生长,而绿藻种类和生物量增加.G0和G1组的种类数和生物量相近但是大于G2组.G0、G1和G2组的平均总生物量分别为98.46、96.09和81.19 mg.L-1.对照组几乎始终是皮状席藻(***)和两栖颤藻(***)等蓝藻为第一优势种,而投加硫酸盐的G1和G2组优势种从皮状席藻和小颤藻(***)等蓝藻向四尾栅藻(***)、放射多芒藻(***)和斜生栅藻(***)等绿藻演替.群落平均多样性指数与对照组G0(1.49±0.32)相比,投加硫酸盐的G1(1.70±0.18)与G2组(1.68±0.40)均有提高.

关键词：硫酸盐浮游藻类群落结构

Transanal vs laparoscopic total mesorectal excision for rectal cancer:a multicenter randomized phase III clinical trial(TaLaR trial)protocol

在线全文

学校读者我要写书评

暂无评论

Gastroenterology Report 2021年第1期9卷 71-76,I0002页

作者： Liang Kang Ziwei Zeng Shuangling Luo Hong Zhang Quan Wang Mingyang Ren Miao Wu Weidong Tong Qing Xu Yi Xiao Aiwen Wu yuan-guang Chen Bo Feng Zhanlong Shen Liang huang Xingwei Zhang Minhua Zheng Jian-Ping Wang Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China guangdong Institute of Gastroenterology The Sixth Affiliated Hospital of Sun Yatsen UniversityGuangzhouGuangdongP.R.China guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of Colorectal Surgery Shengjing Hospital of China Medical UniversityShenyangLiaoningP.R.China Department of Gastrointestinal Surgery The First Hospital of Jilin UniversityChangchunJilinP.R.China Department of Gastrointestinal Surgery The Affiliated Nanchong Central Hospital of North Sichuan Medical CollegeNanchongSichuanP.R.China Department of Gastrointestinal Surgery The Second People’s Hospital of YibinYibinSichuanP.R.China Department of General Surgery Daping HospitalArmy Medical universityChongqingP.R.China Department of Gastrointestinal Surgery Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiP.R.China Department of General Surgery Peking Union Medical College HospitalPeking Union Medical College and Chinese Academy of Medical SciencesBeijingP.R.China Department of Gastrointestinal Surgery Peking University Cancer HospitalBeijingP.R.China Department of Gastrointestinal Surgery The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdongP.R.China Ruijin Hospital Shanghai Jiaotong University School of Medicine ShanghaiP.R.China Department of Gastrointestinal Surgery Peking University People’s HospitalBeijingP.R.China

Background:Total mesorectum excision(TME)is considered the standard surgical procedure for rectal-cancer *** TME(taTME)is a new procedure to treat low rectal *** published studies have proven that taTME can provide a better-quality resected specimen in low-rectal-cancer patients in comparison to the transabdominal procedure,yet long-term outcomes must be *** designed this non-inferiority trial(TaLaR trial)to compare short-term and long-term outcomes between taTME and laparoscopic TME(lapTME)for rectal ***:The TaLaR trial is a phase III open-labeled multicenter randomized-controlled *** who are diagnosed with rectal cancer with no more than T3N2 stage,and with the tumor location below the peritoneal reflection by magnetic resonance imaging scan,digital rectal examination,or colonoscopy,qualify for this *** calculating,a total of 1,114 patients(557 per group)will be randomly allocated to either the taTME or the lapTME *** endpoints are the 3-year disease-free survival(DFS)rate and the 5-year overall survival(OS)*** endpoints include specimen quality,perioperative results,pelvic and anal function,and quality of ***:The TaLaR trial is expected to clarify whether taTME can achieve comparable oncological outcomes,as well as improve specimen quality and recovery conditions in rectal-cancer patients compared with lapTME.

关键词： transanal total mesorectal excision total mesorectal excision laparoscopic rectal cancer surgery

臭氧生物活性炭法在饮用水深度处理中的试验研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

华北电力大学学报（自然科学版） 2006年第1期33卷 98-102页

作者：胡志光昌晶常爱玲惠远峰华北电力大学环境科学与工程学院河北保定071003

利用臭氧氧化与生物活性炭联用技术,在自行设计的试验流程上进行饮用水深度处理可行性试验。用该流程去除水中有机微污染物,CODMn去除率接近50%,浊度和色度大大降低。试验对比了在不同臭氧投加量时,单纯臭氧氧化法与臭氧生物活性炭法(O3... 详细信息

利用臭氧氧化与生物活性炭联用技术,在自行设计的试验流程上进行饮用水深度处理可行性试验。用该流程去除水中有机微污染物,CODMn去除率接近50%,浊度和色度大大降低。试验对比了在不同臭氧投加量时,单纯臭氧氧化法与臭氧生物活性炭法(O3-BAC)在饮用水深度处理中的净化程度,确定出较理想经济的臭氧投加量:4mg/L。验证了在最佳操作条件下,臭氧生物活性炭法比常规氯氧化消毒法对有机物有更好的去除效果。

关键词：饮用水深度处理给水处理臭氧氧化生物活性炭

Preservation of the continence function after intersphincteric resection using a prolapsing technique in the patients with low rectal cancer and its clinical prognosis

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2008年第20期121卷 2016-2020页

作者： DAI Yong JIANG Jin-bo BI Dong-song JIN Zu-tao SUN Jing-zhong hu San-yuan Shandong Univ Qilu Hosp Dept Gen Surg Jinan 250012 Shandong Peoples R China

Background The technique of intersphincteric resection of tumors combined with coloanal anastomosis has been used to avoid permanent colostomy for patients with a rectal cancer located 〈5 cm from the anal verge. This study aimed at assessing the preservation of continence function of the residual rectum and the clinical prognosis of patients with lower rectal cancer after intersphincteric resection using a prolapsing technique. Methods This study included patients with the following inclusion criteria：（1） pathological evidence of rectal cancer and the tumors within distal margins located 5 cm or less from the anus by preoperative endoscopic examination; （2） no evidence by MRI of infiltration of either the external sphincter, puborectalis or the levator muscle; （3） the patients are eligible for intersphincteric resection and lower coloanal anastomosis with a preoperative biopsy showing the tumors with well-to-moderate differentiation. From January 2000 to June 2004, 23 patients with low rectal cancer were included in this study. We used the standard abdominoperineal approach to perform radical resection of tumors with excision of the mesorectum and total or part of the internal sphincters. The patients were followed for assessment of the function of the residual rectum and of cancer recurrence after the operations. Results The median tumor distance from the anal margin was 4.5 （range 3.5-5.0） cm and the mean distal surgical margin 1.6 （range 1.0-2.0） cm. Cancer was classified into Stage Ⅰ （30.4%）, Stage Ⅱ （47.8%）, and Stage Ⅲ （21.7%） according to the TNM classification. Two patients developed anastomotic fistula after the surgical resection and 2 patients （8.7%） developed later stages of anastomotic stricture at the site of coloanal anastomosis. The median follow-up period was 31.5 months （range 12-54） and 2 patients （8.7%） developed local recurrence. Three deaths were associated with distal organ metastasis. Twenty patients （87.0%） have maintained competence to

关键词： rectal cancer anus-sparing operation intersphincteric resection continence function

Decoupling species richness variation and spatial turnover in beta diversity across a fragmented landscape

在线全文

学校读者我要写书评

暂无评论

Decoupling species richness variation and spatial turnover i...

Enhanced interaction of p65 with demethylated P2X3 gene contributes to bone cancer pain in rats

第七届浙江省生物多样性保护研讨会

作者： guang hu Maxwell C.Wilson Jianguo Wu Jingjing Yu Mingjian Yu Department of Landscape Architecture School of Civil Engineering and ArchitectureZhejiang Sci-Tech University School of Life Sciences Arizona State University School of Sustainability Arizona State University College of Life Sciences Zhejiang University

How habitat fragmentation affects the relationship between local richness and the variation in community structure across space is important to both ecology and conservation biology,but has rarely been *** we present an empirical study to address this topic in a fragmented landscape,Thousand Island Lake,an artificial land-bridge island system with more than 1000 islands,which provides an "experimental" fragmented landscape with homogeneous matrix and synchronous successional *** composition and plant functional type were measured across 29 *** tested the effects of island area and isolation on the relationship between α-and β-*** partitioning was used to decouple α-diversity variation and α-independent spatial turnover in β-*** found the variation in species richness,not spatial turnover,drove the variation in community *** also found that area affected both α-and β-diversity,but did not change theα-independent spatial *** filtering and responses of plant functional types were the underlying driving *** plant communities within the Thousand Island Lake system,habitat fragmentation influences β-diversity by modifying local α-diversity,not spatial *** results highlight the importance of hierarchical linkages between components of biodiversity across scales in fragmented landscapes,and have practical conservation implications.

关键词： Area effect Environmental filtering Isolation Land-bridge islands Plant functional type Thousand Island Lake

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Enhanced interaction of p65 with demethylated P2X3 gene cont...

阿司匹林与尼莫地平预处理可改善脑缺血再灌注损伤

中国神经科学学会第十届全国学术会议

作者： You-Lang Zhou Hong-Hong Zhang Yun-Yun Rui Hong-Yan Zhu Zhen-yuan Song Xian Qin Xiao-Wen Meng Shufen hu guang-Yin Xu Institute of Neuroscience Suzhou Key Laboratory of Pain Research and Therapy Department of NeurobiologySoochow University

Objective Pain in primary or metastatic bone cancer severely compromises the quality of life of patients,and the mechanism underlying the development of pain remains largely *** present study was designed to investigate roles for nuclear factor-kappa B（NF-kappaB） and purinergic receptor（P2X3） signaling pathway in female adult rats with bone ***:Bone cancer model was established by injection of Walker 256 rat mammary gland carcinoma cells into rat ***-cell patch clamp recordings were used to measure ATP-evoked responses of tibia specific dorsal root ganglion（DRG,L2-L5） neurons from control and tumor-treated ***-time polymerase chain reaction（qPCR） and western blot analysis were employed to measure expression of p2x3 and related genes at mRNA and protein *** status of p2x3 gene promoter was examined in DRGs using methylation-specific polymerase chain reaction（MSP） and Bisulfite sequencing（BSP）.The interaction between p65 and promoter region of p2x3 gene was identified by chromatin immunoprecipitation *** studies were carried out to determine whether P2X3 was co-expressed with p65 in tibia specific DRG *** Treatment with P2X3receptor inhibitor suramin significantly attenuated mechanical allodynia in bone cancer rats,in a dose-dependent *** cell injection potentiates fast-activating ATP currents in tibia-specific DRG neurons when compared with control *** of P2X3 and p65 were significantly increased in DRGs in bone caner *** of NF-kappaB signaling using pyrrolidine dithiocarbamate reversed the upregulation of P2X3 ***,tumor cell injection also led to a significant demethylation of CpG islands in p2x3 gene promoter region while remarkably downregulated expression of DNA mefhyltransferase 3a and *** importantly,tumor cell injection significantly enhanced the ability of p65 to bind the promoter region of p2x3 *** Our findin

关键词： bone caner pain dorsal root ganglion P2X3 receptor p65 DNA demethylation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

解剖学报 2020年第1期51卷 21-25页

作者：刘倩虎亚光柴尔青甘肃省人民医院脑血管病中心兰州730000 甘肃省妇幼保健院科技发展部兰州730030

目的探讨阿司匹林与尼莫地平预处理对脑缺血再灌注预后的影响。方法 80只健康雄性SD大鼠随机分为假手术组、模型组、阿司匹林预处理组以及阿司匹林+尼莫地平预处理组,每组20只。以线栓法建立大鼠脑缺血再灌注模型,各组大鼠均于模型制作... 详细信息

目的探讨阿司匹林与尼莫地平预处理对脑缺血再灌注预后的影响。方法 80只健康雄性SD大鼠随机分为假手术组、模型组、阿司匹林预处理组以及阿司匹林+尼莫地平预处理组,每组20只。以线栓法建立大鼠脑缺血再灌注模型,各组大鼠均于模型制作前5 d开始灌胃给药,连续用药5 d。假手术组和模型组给予生理盐水;阿司匹林预处理组灌胃给予阿司匹林50 mg/kg;阿司匹林+尼莫地平预处理组灌胃给予阿司匹林50 mg/kg+尼莫地平10 mg/kg。缺血2 h及再灌注24 h后比较各组神经功能缺失评分,用TTC染色测定脑梗死体积,用ELISA法测定脑组织中超氧化物歧化酶(SOD)、丙二醛(MDA)、血栓素B2和6-酮-前列腺素1α的含量,并通过Real-time PCR检测大鼠Notch1、Jagged1和Hes1 mRNA表达以及通过Western blotting检测Notch信号通路中Notch1、Jagged1及下游物质Hes1的表达水平。结果与模型组相比,阿司匹林+尼莫地平预处理组神经功能缺损评分显著降低(P<0. 05),脑梗死体积显著缩小;阿司匹林预处理组和阿司匹林+尼莫地平预处理组脑组织SOD及6-酮-前列腺素1α显著高于模型组,MDA、血栓素B2及血栓素B2/6-酮-前列腺素1表达均低于模型组,且阿司匹林+尼莫地平预处理组变化更明显(P<0. 05);阿司匹林预处理组和阿司匹林+尼莫地平预处理组的Notch1、Jagged1和Hes1 mRNA及蛋白表达水平显著低于模型组(P<0. 05),且阿司匹林+尼莫地平预处理组表达量低于阿司匹林预处理组(P<0. 05)。结论阿司匹林与尼莫地平两药合用时明显优于阿司匹林单独给药,可显著改善大鼠脑缺血再灌注损伤,这可能是通过影响Notch信号通路达到脑组织保护的作用。

关键词：阿司匹林尼莫地平脑缺血再灌注 Notch信号通路免疫印迹法大鼠

Dialectical behavior therapy-based psychological intervention for woman in late pregnancy and early postpartum suffering from COVID-19:a case report

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2020年第5期21卷 394-399页

作者： Jin-wen huANG Xiao-yi ZHOU Shao-jia LU Yi XU Jian-bo hu Man-li huANG hua-fen WANG Chan-chan hu Shu-guang LI Jing-kai CHEN Zhong WANG Shao-hua hu Ning WEI Department of Psychiatry the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China The Key Laboratory of Mental Disorder Management in Zhejiang Province Hangzhou 310003China Zhejiang Engineering Center for Mathematical Mental Health Hangzhou 310003China Department of Nursing the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

目的:孕产妇的心理健康风险较为突出,但尚未有文献说明何种心理干预方式对患有新冠肺炎的围产期孕妇有效。本文报告了一例确诊新冠肺炎的35周2天孕妇在入住隔离病房后,使用辩证行为治疗(DBT)相关技术对其存在的抑郁和焦虑症状在围产期... 详细信息

目的:孕产妇的心理健康风险较为突出,但尚未有文献说明何种心理干预方式对患有新冠肺炎的围产期孕妇有效。本文报告了一例确诊新冠肺炎的35周2天孕妇在入住隔离病房后,使用辩证行为治疗(DBT)相关技术对其存在的抑郁和焦虑症状在围产期进行持续心理干预的案例,旨在探究以DBT为基础的短程心理治疗对围产期新冠肺炎患者的抑郁和焦虑症状的改善作用。创新点:首例对确诊新冠肺炎的孕产妇进行产前及产后心理评估及干预的案例。也是首次报道在公共卫生危机事件的个体干预中使用了DBT相关技术。方法:患者,女,30岁,孕35周+2天,干咳两天就诊,在当地医院进行新型冠状病毒核酸测验提示阳性后转入浙江大学医学院附属第一医院住院治疗。2020年2月8日行剖腹产,产后继续在隔离病房治疗。入院后精神科访谈及心理测量均提示存在抑郁和焦虑症状,于2月7日、10日、16日进行三次心理干预,主要使用DBT相关干预技术,包括放松训练、正念练习、情绪控制技巧训练、人际支持等。期间根据患者的需要及时调整干预策略。通过三次心理干预,患者的抑郁、焦虑症状得到改善,抑郁和焦虑量表评分与基线比显著下降。结论:本报告显示了对确诊新冠肺炎的隔离病房患者及时进行心理干预的必要性。心理干预能有效改善患者的抑郁、焦虑症状,减少或避免了精神类药物的使用,为新冠肺炎的临床治疗提供了支持。此报告也为以DBT为基础的心理治疗在危机干预中的应用提供了临床证据。

关键词：新冠肺炎孕期产后心理干预辨证行为治疗

基于DBN威胁评估的MPC无人机三维动态路径规划

在线全文

学校读者我要写书评

暂无评论

系统工程与电子技术 2014年第11期36卷 2199-2205页

作者：高晓光李青原邸若海西北工业大学电子信息学院陕西西安710072

模型预测控制(model predictive control,MPC)路径规划算法适用于三维动态环境下的无人机(unmanned aerial vehicle,UAV)路径规划;动态贝叶斯网络(dynamic Bayesian network,DBN)能够有效推理战场态势,对无人机进行威胁评估。针对威胁... 详细信息

模型预测控制(model predictive control,MPC)路径规划算法适用于三维动态环境下的无人机(unmanned aerial vehicle,UAV)路径规划;动态贝叶斯网络(dynamic Bayesian network,DBN)能够有效推理战场态势,对无人机进行威胁评估。针对威胁尾随无人机时的路径规划问题,构建DBN威胁评估模型,将UAV在战场环境中的威胁态势用威胁等级概率表示,与MPC路径规划算法相结合,得到基于DBN威胁评估的MPC UAV路径规划算法。通过多组仿真分析表明,在三维动态环境下,特别是威胁尾随无人机时,基于DBN威胁评估的MPC无人机路径规划算法可以得到有效的无人机路径。

关键词：无人机路径规划模型预测控制动态贝叶斯网络动态威胁评估