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STATUS, CAUSES AND COMBATING SUGGESTIONS OF SANDY DESERTIFICATION IN QINGHAI-TIBET PLATEAU

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Chinese Geographical Science 2005年第4期15卷 289-296页

作者： liU Yi-hua DONG guang-rong li sen DONG Yu-xiang School of Geography Guangzhou University Guangzhou 510405 P. R. China Cold and A rid Regions Environment and Engineering Research Institute Chinese Academy of Sciences Lanzhou 730000 P. R. China Department of Tourism and Geography Foshan University Foshan 528000 P. R. China Department of Territorial Resource and Environment SUN Yat-Sen University Guangzhou 510275 P. R. China

The Qinghai-Tibet Plateau is one of the major sandy desertification regions of China. Based on the recent investigation on sandy desertification, this paper analyses the status such as the type, area, distribution and damage of sandy land desertification in the plateau. Through the analysis on the factors affecting sandy desertification in the region’s natural and socio-economic systems as well as the processes and their interrelations, it can be concluded that sandy desertification in the Qinghai-Tibet Plateau resulted from the combined actions of normal natural sand drift processes, natural sandy desertification processes caused by climatic changes and man-made sandy desertification caused by improper human activities. In addition, it also predicts the possible developmental trend including the increase in desertification area and the enhancement in desertification developmental degree with the exacerbation of the complex processes, and finally puts forward some strategic suggestions to combat sandy desertification in the coming years.

关键词： Qinghai-Tibet Plateau sandy desertification desertification control

Increase in the variability of terrestrial carbon uptake in response to enhanced future ENSO modulation

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 32-38页

作者： Younong li li Dan Jing Peng Qidong Yang Fuqiang Yang Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Key Laboratory of Atmospheric Environment and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunmingChina

El Niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air *** the ENSO modulation and carbon flux variability are projected to increase in the future,but their connection still needs further *** investigate the impact of future ENSO modulation on carbon flux variability,this study used 10 CMIP6 earth system models to analyze ENSO modulation and carbon flux variability in middle and low latitudes,and their relationship,under different scenarios simulated by CMIP6 *** results show a high consistency in the simulations,with both ENSO modulation and carbon flux variability showing an increasing trend in the *** higher the emissions scenario,especially SSP5-8.5 compared to SSP2-4.5,the greater the increase in *** flux variability in the middle and low latitudes under SSP2-4.5 increases by 30.9%compared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences mid-and low-latitude carbon flux variability primarily through *** occurrence may potentially be attributed to the increased responsiveness of gross primary productivity towards regional temperature fluctuations,combined with the intensified influence of ENSO on land surface temperatures.

关键词： Carbon variability ENSO modulation CMIP6 models

Melting Characteristics and Wettability of Binding Phase in Sinter

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Journal of Iron and Steel Research International 2009年第3期16卷 1-5页

作者： SHEN Feng-man li guang-sen DING Zhi-min MU lin School of Materials and Metallurgy Northeastern University Shenyang 110004 Liaoning China

The melting characteristics and wettability of the binding phase in high basicity sinter were studied. By changing nCaO∶nFe2O3 （molar ratio of CaO to Fe2O3） as well as the percentage of MgO,SiO2,and Al2O3,the melting characteristics and wettability of the binding phase were discussed. The results indicated that the characteristic melting temperature was the lowest and wettability was the best at nCaO∶nFe2O3=1∶1 （without addition）; the addition of MgO increased the characteristic melting temperature and contact angles; when the percentage of SiO2 or Al2O3 was 3%,the characteristic melting temperature was the lowest,whereas the contact angles increased with an increase in SiO2 and Al2O3 contents.

关键词： sinter binding phase characteristic melting temperature contact angle

Investigations on the Interactions between li-TFSI and Glass Fibers in the Ternary PP/GF/li-TFSI Composites

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Chinese Journal of Polymer Science 2018年第1期36卷 113-118页

作者： sen-lin Gu Huan-Huan liu Huan Cao Claude Mercier Yong-Jin li College of Material Chemistry and Chemical EngineeringHangzhou Normal UniversityHangzhou 310036China Solvay Co.Ltd shanghai 201100China

The polypropylene/glass fiber（PP/GF） composites with excellent antistatic performance and improved mechanical properties have been reported by incorporation of a very small amount of the organic salt, lithium bis（trifluoromethanesulfonyl）imide（li-TFSI）, into the PP/GF composites. It was considered that GF could play the role as the pathways for the movements of ions in the ternary composites. In this work, the interactions between li-TFSI and glass fiber and the effects of such interactions on the physical properties of the composites have been systematically investigated. Three types of glass fibers with different ―OH group concentrations have been prepared in order to compare the interactions between GF and li-TFSI. It was found that the ―OH group concentrations on the surface of glass fiber have significant effects on interactions between glass fibers and li-TFSI. Such interactions are crucial for both the antistatic and mechanical performances of the final PP/GF/li-TFSI composites. The investigation indicated that the GF with high ―OH group concentrations confined the movement of TFSI-, which decreased the antistatic properties of PP/GF/li-TFSI composites. On the other hand, the GF with low ―OH group concentrations inhibited the absorption of li-TFSI onto the GF, which also hindered the formation of li-TFSI conductive pathway. The best antistatic performance of the ternary composites can be achieved at the intermediate ―OH concentrations on the GF.

关键词： Polypropylene Glass fiber li-TFSI Antistatic performance

Claudin-15 overexpression inhibits proliferation and promotes apoptosis of Schwann cells in vitro

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Neural Regeneration Research 2020年第1期15卷 169-177页

作者： Jian-Nan li Zhan Zhang guang-Zhi Wu Deng-Bing Yao Shu-sen Cui China-Japan Union Hospital of Jilin University ChangchunJilin ProvinceChina School of life Sciences Jiangsu Key Laboratory of NeuroregenerationCo-innovation Center of NeuroregenerationNantong UniversityNantongJiangsu ProvinceChina

Our previous experiments have discovered that Claudin-15 was up-regulated in Schwann cells of the distal nerve stumps of rat models of sciatic nerve ***,how Claudin-15 affects Schwann cell function is still *** study aimed to identify the effects of Claudin-15 on proliferation and apoptosis of Schwann cells cultured in vitro and explore the underlying *** Schwann cells were obtained from ***-15 in Schwann cells was knocked down using siRNA(siRNA-1 group)compared with the negative control siRNA transfection group(negative control group).Claudin-15 in Schwann cells was overexpressed using pGV230-Claudin-15 plasmid(pGV230-Claudin-15 group).The pGV230 transfection group(pGV230 group)acted as the control of the pGV230-Claudin-15 *** proliferation was analyzed with EdU *** apoptosis was analyzed with flow cytometric *** migration was analyzed with Transwell *** mRNA and protein expressions were analyzed with quantitative polymerase chain reaction assay and western blot *** results showed that compared with the negative control group,cell proliferation rate was up-regulated;p-AKT/AKT ratio,apoptotic rate,p-c-Jun/c-Jun ratio,mRNA expression of protein kinase C alpha,Bcl-2 and Bax were down-regulated;and mRNA expression of neurotrophins basic fibroblast growth factor and neurotrophin-3 were increased in the siRNA-1 *** significant difference was found in cell migration between the negative control and siRNA-1 *** with the pGV230 group,the cell proliferation rate was down-regulated;apoptotic rate,p-c-Jun/c-Jun ratio and c-Fos protein expression increased;mRNA expression of protein kinase C alpha and Bax decreased;and mRNA expressions of neurotrophins basic fibroblast growth factor and neurotrophin-3 were up-regulated in the pGV230-Claudin-15 *** above results demonstrated that overexpression of Claudin-15 inhibited Schwann cell proliferation and promoted Schwann cell apopt

关键词： apoptosis Bax cell proliferation c-Jun Claudin-15 nerve regeneration peripheral nerve injury protein kinase C alpha Schwann cells Wallerian degeneration

Morphology and size controlled synthesis of Co-doped MIL-96 by different alkaline modulators for sensitively detecting alpha-fetoprotein

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Chinese Chemical Letters 2020年第9期31卷 2263-2267页

作者： Chaonan Gu Jingjing li guang Yang liming Zhang Chun-sen liu Huan Pang Henan Provincial Key Laboratory of Surface&Interface Science Zhengzhou University of Light IndustryZhengzhou 450002China School of Chemistry and Chemical Engineering Guangling CollegeYangzhou UniversityYangzhou 225009China School of Chemistry and Chemical Engineering Henan University of TechnologyZhengzhou 450001China

This work introduces a simple and facile approach for the morphology and size controlled synthesis of Co-doped *** using different bases as modulators,Co-doped MIL-96 was obtained with sizes that varied from 5 μm to 300 nm,and four different morphologies,including hexagonal prism,icosahedron,hexagonal spindle and *** these,nano-sized Co-doped MIL-96 with an ellipsoid morphology exhibited the highest electroactive surface area and good conductivity as well as the best electrochemical sensing performance towards α-fetoprotein.

关键词： Morphology/size MIL-96 Modulator Aptasensor Alpha-fetoprotein

Local magnetic moment oscillation around an Anderson impurity on graphene

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 192-201页

作者： Shuai li Zhen Ma Jin-Hua Gao School of Science Hebei University of Science and Technology School of Electronics and Information Zhengzhou University of Light Industry School of Physics and Wuhan National High Magnetic Field Center Huazhong University of Science and Technology

We theoretically investigate the spin resolved Friedel oscillation （FO） and quasiparticle interference （QPI） in graphene induced by an Anderson *** the impurity becomes magnetic,the resulted FO becomes spin dependent,which gives rise to a local magnetic moment oscillation with an envelop decaying as r-2in real space in the doping ***,at half filling,the electron density and local magnetic moment will not oscillate but decay as *** spin resolved FO has both sublattice and spin ***,the local magnetic moment decay at half filling only occurs at one sublattice of graphene,which is quite like the phenomenon observed in the STM experiment (***ález-Herrero et al.,Science 352,437 （2016）).We further give an analytic formula about such spin dependent FO based on the stationary phase ***,we study the interference of quasiparticles around the magnetic impurity by calculating the spin dependent Fourier-transformed local density of states （FT-LDOS）.Our work gives a comprehensive understanding about the local magnetic moment oscillation around an Anderson impurity on graphene.

关键词： Friedel oscillation local magnetic moment graphene Anderson impurity

Potent anti-angiogenicactivity of B19—a mono-carbonyl analogue of curcumin

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Chinese Journal of Natural Medicines 2014年第1期12卷 8-14页

作者： SUN li liU Jin liN sen-sen SHI Wen-Ting ZHU Jing liANG guang YUAN Sheng-Tao Jiangsu Center for Drug Screening China Pharmaceutical University Nanjing 210009 China Jiangsu Center for Pharmacodynamics Research and Evaluation China Pharmaceutical University Nanjing 210009 China Wenzhou Medical College Pharmacy School Wenzhou 325035 China

AIM： The compound B19 （C21H22O5） is a newly synthesized, mono-carbonyl analog of curcumin that has exhibited potentialantitumor effects. This present study was performed to identify the anti-angiogenic activity of this compound. METHODS AND RESULTS： B19 inhibited migration and tube formation of human umbilical vein endothelial cells, and arrested microvessel outgrowth from rat aortic *** addition, B19 suppressed the neovascularization of chicken chorioallantoic membrane. Mechanistic studies revealed that B19 suppressed the downstream protein kinase activation of vascular endothelial growth factor （VEGF） by decreasing phosphorylated forms of serine/threonine kinase Akt, extracellular signal-regulated kinase, and p38 mitogen-activated protein kinase, with or without stimulating vascular endothelial growth factor （VEGF）. CONCLUSIONS： B 19 exerted anti-angiogenic activity in vitro and ex vivo, which suggests that it merits further investigation as a promising anticancer angiogenesis compound.

关键词： B 19 Curcumin derivative Angiogenesis Human umbilical vein endothelial cell (HUVEC) Vascular endothelial growth factor (VEGF)

Targeting epigenetic mechanisms in amyloid-β-mediated Alzheimer’s pathophysiology:unveiling therapeutic potential

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Neural Regeneration Research 2025年第1期20卷 54-66页

作者： Jennie Z.li Nagendran Ramalingam Shaomin li Ann Romney Center for Neurologic Diseases Brigham and Women’s Hospital and Harvard Medical SchoolBostonMAUSA

Alzheimer’s disease is a prominent chronic neurodegenerative condition characterized by a gradual decline in memory leading to *** evidence suggests that Alzheimer’s disease is associated with accumulating various amyloid-βoligomers in the brain,influenced by complex genetic and environmental *** memory and cognitive deficits observed during the prodromal and mild cognitive impairment phases of Alzheimer’s disease are believed to primarily result from synaptic *** life,environmental factors can lead to enduring changes in gene expression and the emergence of brain *** changes,known as epigenetic modifications,also play a crucial role in regulating the formation of synapses and their adaptability in response to neuronal *** this context,we highlight recent advances in understanding the roles played by key components of the epigenetic machinery,specifically DNA methylation,histone modification,and microRNAs,in the development of Alzheimer’s disease,synaptic function,and activity-dependent synaptic ***,we explore various strategies,including enriched environments,exposure to non-invasive brain stimulation,and the use of pharmacological agents,aimed at improving synaptic function and enhancing long-term potentiation,a process integral to epigenetic ***,we deliberate on the development of effective epigenetic agents and safe therapeutic approaches for managing Alzheimer’s *** suggest that addressing Alzheimer’s disease may require distinct tailored epigenetic drugs targeting different disease stages or pathways rather than relying on a single drug.

关键词： Alzheimer’s disease DNA methylation enriched environments histone modification microRNAs non-invasive brain stimulation synaptic plasticity