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不同栽培型白花前胡质量形成的代谢组学研究

中国中药杂志 2024年第3期49卷 681-690页

作者：郭瑀徐广罗舜罗敏杨丹谭秋生杨永东邓才富重庆市药物种植研究所重庆市道地药材规范化生产工程技术研究中心重庆400485

为明确不同栽培型白花前胡的代谢差异,揭示质量形成机制,为前胡种质挖掘与利用提供参考依据。该研究基于超高效液相色谱-质谱联用技术(UHPLC-MS/MS),对同一产地、同一时期的6种栽培型前胡(YS、H、LZ、LY、LX、Z)进行非靶向代谢组学分析... 详细信息

为明确不同栽培型白花前胡的代谢差异,揭示质量形成机制,为前胡种质挖掘与利用提供参考依据。该研究基于超高效液相色谱-质谱联用技术(UHPLC-MS/MS),对同一产地、同一时期的6种栽培型前胡(YS、H、LZ、LY、LX、Z)进行非靶向代谢组学分析,利用主成分分析、正交偏最小二乘法判别分析、单变量统计分析等方法筛选不同栽培型前胡的差异代谢物,根据质荷比、数据库KEGG、相关文献、相关性分析确定与质量形成相关的潜在标志代谢物,识别代谢途径,分析质量形成过程。结果表明,6种栽培型前胡代谢物存在明显差异,正、负离子模式下,分别得到571、465种差异代谢物。其中,与质量形成相关的潜在标志代谢物22种,涉及苯丙烷生物合成、植物激素的生物合成及苯丙氨酸、酪氨酸和色氨酸生物合成等9种潜在靶向代谢通路。与YS型相比,各栽培型前胡中与苯丙烷生物合成相关的补骨脂素、欧前胡素、鲁望桔内酯下降,7-羟基香豆素、秦皮乙素、二氢欧山芹素、茉莉酸升高;其他代谢途径的2-琥珀酰苯甲酸酯、独活属醇、L-酪氨酸下降,以Z、H型的变化最大。因此,合理调控苯丙烷生物合成途径是栽培型前胡质量提升的关键机制之一,Z、H型具有更优的质量形成代谢过程可用于前胡优质种质的筛选与挖掘。

关键词：前胡栽培型标志代谢物质量形成代谢组学

Visible light induced photodegradation of organic pollutants on nitrogen and fluorine co-doped TiO_2 photocatalyst

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Journal of Environmental Sciences 2005年第1期17卷 76-80页

作者： WANGZheng-peng XUJun CAIWei-min zhouBao-xue HEZheng-guang CAIChun-guang HONGXiao-ting SchoolofEnvironmentalScienceandEngineering ShanghaiJiaotongUniversityShanghai200240China

The nitrogen and fluorine co doped TiO 2 polycrystalline powder was synthesized by calcinations of the hydrolysis product of tetra butyl titanate with ammonium fluoride. Nitrogen and fluorine co doping causes the absorption edge of TiO 2 to shift to a lower energy region. The photocatalytic activity of co doped TiO 2 with anatase phases was found to be 2 4 times higher than that of the commercial TiO 2 photocatalyst Degussa P25 for phenol decomposition under visible light irradiation. The co doped TiO 2 powders only contain anatase phases even at 1000℃. Apparently, ammonium fluoride added retarded phase transformation of the TiO 2 powders from anatase to rutile. The substitutional fluorine and interstitial nitrogen atoms in co doped TiO 2 polycrystalline powder were responsible for the vis light response and caused the absorption edge of TiO 2 to shift to a lower energy region.

关键词： photocatalyst visible light nitrogen and fluorine co-doped phenol band gap

广东生态环境宣传教育融媒平台的建设与探索实践

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中国环保产业 2024年第6期 47-50页

作者：梁光源李介民广东省环境保护宣传教育中心广州510000 拓尔思信息技术股份有限公司北京100098

本文从平台建设背景、平台运营、平台推广等方面,综合介绍了广东省生态环境宣传教育融媒平台的建设成效,并指出了目前存在的问题与不足,阐述了融媒信息化平台在推进环境治理体系现代化、提高环境宣传教育工作效率、促进公众参与的积极... 详细信息

本文从平台建设背景、平台运营、平台推广等方面,综合介绍了广东省生态环境宣传教育融媒平台的建设成效,并指出了目前存在的问题与不足,阐述了融媒信息化平台在推进环境治理体系现代化、提高环境宣传教育工作效率、促进公众参与的积极作用。

关键词：广东生态环境保护宣传教育融媒信息化

维普期刊数据库博看期刊

Rapidly Progressing Fatal Case of Natural Killer/T-Cell Lymphoma Presenting as Orbital Inflammation

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Chinese Medical Journal 2018年第16期131卷 2013-2014页

作者： guang-min Tang Tian-Cong Chang Xiang Tu Guan-Yu zhou Zhen-Zhen Liu Center of Infectious Diseases West China Hospital Sichuan University Chengdu Sichuan 610041 China Department of Ophthalmology West China Hospital Sichuan University Chengdu Sichuan 610041 China West China Medical School Sichuan University Chengdu Sichuan 610041 China

To the Editor： Natural killer T-cell lymphoma （NKTCL） is a rare form of non-Hodgkin＇s lymphoma （NHL） that constitutes 1 3% of all cases of orbital NHL. Orbital NKTCL is known as a ＂masquerade syndrome＂ with myriad presentations This case reported a 45-year-old male with primary NKTCL of the orbit initially presenting as orbit inflammation but eventually progressing to systemic aggressive disease.

关键词： INVOLVEMENT

Real-time Quantitative RT-PCR for CT9 Level in Human Cancer

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Chemical Research in Chinese Universities 2006年第2期22卷 185-188页

作者： JIN Xiang-qun ZHANG Jing-min XU Hui zhou Yan WANG guang-shu ZHAO Yan-qiu ZHANG Han-qi College of Chemistry Jilin University Changchun 130012 P. R. China College of Phamercy Jilin University Changchun 130021 P. R. China College of Nurse Jilin University Changchun 130021 P. R. China No. 2 Affiliated Hospital Jilin University Changchun 130021 P. R. China

CT9 is a recently cloned cancer-testis antigen, which is a member of the bromodomain and extraterminal family. Each member of this protein family contains two N-terminal bromodomain motifs. We investigated the distribution of CT9 in different tissues and the possibility for it to be used as a potential therapeutic target in cancer treament. By using the real-time RT-PCR method and 18SrRNA as an internal standard, we analyzed the CT9 expression in several normal human tissues and in the tissues of patients suffering from cancer. The result of this study shows that the highest level of mRNA is only present in testis tissue because the CT9 expression has not been detected in other normal tissues. In 6 of 10 cases of gastric adenocarcinoma, in 3 of 10 cases of esophageal squamous cell carcinoma, in 2 of 9 cases of endometrial carcinoma and only in 1 of 12 cases of brain cancer, the low level expression of CT9 was detected. In none of the 12 cases of cervical squamous cell carcinoma, the expression of CT9 was detected. Since the high level expression of CT9 is only found in the normal testis tissue, but the low expression in cancer tissues, for example tissues of cervical squamous cell carcinoma, brain cancer, endometfial adenocarcinoma, esophageal squamous cell carcinoma, we conclude that CT9 cannot be used as a cancer therapeutic target molecule for cervical squamous cell carcinoma, brain cancer, endometrial adenocarcinoma, esophageal squamous cell carcinoma.

关键词： CT9 Cancer-testis antigen Real-time RT-PCR

Impulse pressuring diffusion bonding of titanium to 304 stainless steel using pure Ni interlayer

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Rare Metals 2016年第4期35卷 331-336页

作者： Fang-Li Wang guang-min Sheng Yong-Qiang Deng College of Materials Science and Engineering Chongqing University

In the present study, impulse pressuring diffu- sion bonding technology （IPDB） was utilized between commercially pure titanium and 304 stainless steel （SS） using pure nickel （Ni） as interlayer metal. The interfacial microstructures of the bonded joints were investigated by scanning electron microscopy （SEM） and energy dispersive spectroscope （EDS） analyses. It is found that with the aid of the Ni interlayer, the interdiffusion and reaction between Ti and SS can be effectively restricted and robust joints can be obtained. Intermetallic compounds （IMCs） including Ti2Ni, TiNi, and TiNi3 are detected at the Ti/Ni interface; however, only Ni-Fe solid solution is found at the Ni/SS interface. The maximum tensile strength of 358 MPa is obtained by IPDB for 90 s and the fracture takes place along the Ti2Ni and TiNi phase upon tensile loading. The existence of cleavage pattern on the fracture surface indi- cates the brittle nature of the joints.

关键词： Impulse pressuring diffusion bonding Titanium Stainless steel Ni interlayer

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大型污水泵站进水流态优化设计研究

中国市政工程 2024年第3期 57-60,154,155页

作者：朱洁谭敏海卢光毅上海市城市建设设计研究总院(集团)有限公司上海200125 上海浦东建设管理有限公司上海200125

污水泵站在城市排水系统中,承担传输城市污水的功能,是保证城市排水系统安全稳定的重要设施。由于污水泵站建设容易受用地条件、市政管网布置条件等因素制约,容易引发泵站进水流态紊乱、池体水量分布不匀等问题。以上海市浦东新区灶东... 详细信息

污水泵站在城市排水系统中,承担传输城市污水的功能,是保证城市排水系统安全稳定的重要设施。由于污水泵站建设容易受用地条件、市政管网布置条件等因素制约,容易引发泵站进水流态紊乱、池体水量分布不匀等问题。以上海市浦东新区灶东污水泵站扩建工程为例,在进水闸门井中采用交错式组合梁和导流墩的组合形式优化进水分布,同时在前池中采用八字形导流墩和组合式横梁的组合形式优化入流,能够有效改善前池进水流态,优化各泵组进水条件,从而保障大型污水泵站运行的安全稳定,也为其它相似工程的优化设计提供思路。

关键词：污水泵站进水流态组合梁导流墩优化设计

Isothermal oxidation behavior of a new Re-free nickel-based single-crystal superalloy at 950℃

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Rare Metals 2017年第8期36卷 617-621页

作者： Xue-Feng zhou guang Chen Ya-Ya Feng Zhi-Xiang Qi min-Zhi Wang Pei Li Jia-Lin Cheng Engineering Research Center of Materials Behavior and Design ministry of Education Nanjing University of Science and TechnologyNanjing 210094China School of Chemistry and Materials Engineering Changshu Institute of TechnologyChangshu 215500China School of Materials Science and Engineering Nanjing Instituteof TechnologyNanjing 211167China

The isothermal oxidation behavior of a new Refree nickel-based single-crystal superalloy in air at 950 ℃ for 200 h was studied by scanning electron microscopy（SEM）with energy-dispersive spectroscopy（EDS）and X-ray diffraction（XRD）.The results indicate that oxidation kinetics obeys parabolic law approximately,and the mass gain increases rapidly during initial oxidation stage and then gradually slows *** oxidation scales are composed of three layers：the outer layer mainly consists of NiO with a small amount of CoO;the intermediate layer is mainly composed of Cr_2O_3 with a small amount of spinel compounds such as CrTaO_4,NiCr_2O_4,CoCrAl_2O_4,CoAl_2O_4,and NiAl_2O_4;and the inner layer is composed of Al_2O_*** Al_2O_3 layer suppresses the diffusion of elements between oxygen and alloy elements,slows down the alloy oxidation speed,and also suppresses the growth of the oxide scale and reduces the oxidation rate,which is agreeable with the oxidation kinetics.

关键词： Nickel-based single-crystal superalloy Isothermal oxidation Oxidation kinetic Surfacemorphology

考虑表面粗糙度影响的低温涡轮泵特性与动静间隙流动分析

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西安交通大学学报 2024年第6期58卷 77-89页

作者：卜学兵付平孙中国席光西安交通大学能源与动力工程学院西安710049 西安交通大学未来技术学院西安710049

为分析低温涡轮泵过流部件表面粗糙度对其性能特性的影响,阐明表面粗糙度对涡轮泵动静间隙流场的影响机制,选择增材制造闭式叶轮涡轮氧泵为研究对象,在考虑低温介质热力学效应影响的前提下,采用液氮作为增压输送介质,对涡轮泵低温性能... 详细信息

为分析低温涡轮泵过流部件表面粗糙度对其性能特性的影响,阐明表面粗糙度对涡轮泵动静间隙流场的影响机制,选择增材制造闭式叶轮涡轮氧泵为研究对象,在考虑低温介质热力学效应影响的前提下,采用液氮作为增压输送介质,对涡轮泵低温性能开展实验测试和数值计算。研究结果表明:在13 500~26 000 r/min转速范围内,相较于光滑壁面,考虑过流部件表面粗糙度后,采用液氮作为模拟介质得到的涡轮氧泵数值计算结果与实验测试数据吻合较好;随着离心叶轮及蜗壳等主流表面粗糙度从光滑壁面增加至36μm,涡轮氧泵扬程及效率分别下降了9.1%、10.6%;随着动静间隙过流部件表面粗糙度从0增加至20μm,涡轮泵叶轮轴向力合力系数显著降低了25.8%。研究结果对后续深入揭示表面粗糙度对低温涡轮泵动静间隙流场特性影响规律以及过流部件表面质量分区控制具有重要借鉴意义及参考价值。

关键词：涡轮泵表面粗糙度动静间隙热力学效应轴向力