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A K-nearest Neighbor Model to Predict Early Recurrence of Hepatocellular Carcinoma After Resection

Journal of Clinical and Translational Hepatology 2022年第4期10卷 600-607页

作者： Chuanli Liu Hongli Yang Yuemin feng Cuihong Liu Fajuan Rui Yuankui Cao Xinyu Hu Jiawen Xu Junqing Fan Qiang Zhu jie Li Department of Infectious Disease Shandong Provincial Hospital Affiliated to Shandong Frist Medical UniversityJi'nanShandongChina Department of Infectious Disease Shandong Provincial HospitalCheeloo College of MedicineShandong UniversityJi'nanShandongChina Department of Gastroenterology Shandong Provincial Hospital Affiliated to Shandong Frist Medical UniversityJi'nanShandongChina Department of Ultrasound Diagnosis and Treatment Shandong Provincial Hospital Affiliated to Shandong Frist Medical UniversityJi'nanShandongChina School of Computer Science China Uni-versity of GeosciencesWuhanHubeiChina Department of Pathology Shandong Provincial Hospital Affiliated to Shan-dong Frist Medical UniversityJi'nanShandongChina Department of Infectious Diseases Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjingJiangsuChina Institute of Viruses and Infectious Diseases Nanjing UniversityNanjingJiangsuChina

Background and Aims:Patients with hepatocellular carci-noma(HCC)surgically resected are at risk of recurrence;however,the risk factors of recurrence remain poorly *** study intended to establish a novel machine learning model based on clinical data for predicting early re-currence of HCC after ***:A total of 220 HCC patients who underwent resection were ***-sification machine learning models were developed to predict HCC *** standard deviation,recall,and preci-sion of the model were used to assess the model’s accura-cy and identify efficiency of the ***:Recurrent HCC developed in 89(40.45%)patients at a median time of 14 months from primary *** principal compo-nent analysis,tumor size,tumor grade differentiation,por-tal vein tumor thrombus,alpha-fetoprotein,protein induced by vitamin K absence or antagonist-II(PIVKA-II),aspartate aminotransferase,platelet count,white blood cell count,and HBsAg were positive prognostic factors of HCC recurrence and were included in the preoperative *** compar-ing different machine learning methods,including logistic re-gression,decision tree,naïve Bayes,deep neural networks,and k-nearest neighbor(K-NN),we choose the K-NN model as the optimal prediction *** accuracy,recall,preci-sion of the K-NN model were 70.6%,51.9%,70.1%,*** standard deviation was ***:The K-NN classification algorithm model performed better than the other classification *** of the recurrence rate of early HCC can help to allocate treatment,eventually achieving safe oncological outcomes.

关键词： Hepatocellular carcinoma Surgical resection Recurrence Machine learning Prognostic model

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Geothermal anomalies in the Xianshuihe area: Implications for tunnel construction along the Sichuan-Tibet Railway, China

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地下水科学与工程:英文版 2023年第3期11卷 237-248页

作者： feng Liu Wei Zhang Gui-ling Wang Shuai-chao Wei Chen Yue guang-zheng Jiang Yu-zhong Liao Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological ScienceShijiazhuang 050061China China University of Geosciences(Beijing) Beijing 100083China Technology Innovation Center of Geothermal&Hot Dry Rock Exploration and Development Ministry of Natural ResourcesShijiazhuang 050061China Chengdu University of Technology Chengdu 610059China

This study presents a comprehensively analysis of geothermal characteristics in the Xianshuihe geothermal area along the Sichuan-Tibet Railway,using temperature logging,temperature monitoring and thermal conductivity measurement,and regional geothermal geological survey *** research focuses on the geothermal background,geothermal field,and their potential impact on the surrounding *** investigation reveals that the average heat flow value in the study area is approximately 73.0 mW/m^(2),significantly higher than the average terrestrial heat flow in China's Mainland(62.5 mW/m^(2)).This high terrestrial heat flow signifies a distinct thermal background in the *** addition,geothermal anomalies in the area are found to be closely associated with the distribution of hot springs along NW faults,indicating a strong control by the Xianshuihe fault *** study concludes that the region's favorable conditions for geothermal resources are attributed to the combination of high terrestrial heatflow background and water-conducting ***,these conditions also pose a potential threat of heat damage to the tunnels along the Sichuan-Tibet *** evaluate the risk,the research takes into account the terrestrial heat flow,thermal conductivity of the tunnel surrounding rocks,characteristics of the regional constant temperature layer,as well as the distribution of hot springs and *** analysis specifically focuses on the thermal damage risk of Kangding 1# tunnel and 2# tunnel passing through the study *** on the findings,it is determined that Kangding 1# tunnel and 2# tunnel have relatively low risk of heat damage,as they have avoided most of the high temperature anomaly ***,several sections of the tunnels do traverse zones with low to medium temperatures,where surface rock temperatures can reach up to 45℃.Therefore,these regions should not be neglected during the construction and operation of the tunnel project,and mitigation measu

关键词： Xianshuihe geothermal zone Terrestrial heat flow Hot spring Tunnel Heat damage

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针对一般线性约束的Petri网控制器设计方法(英文)

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软件学报 2005年第3期16卷 419-426页

作者：王寿光颜钢锋浙江大学电气工程学院浙江杭州310027

针对基于Petri网离散事件系统关于标识向量和Parikh向量的不等式约束反馈控制器设计问题,提出一种新的控制器设计方法.该方法首先利用 Petri 网的状态方程把关于标识向量和 Parikh 向量的不等式约束转变成关于Parikh 向量的不等式约束,... 详细信息

针对基于Petri网离散事件系统关于标识向量和Parikh向量的不等式约束反馈控制器设计问题,提出一种新的控制器设计方法.该方法首先利用 Petri 网的状态方程把关于标识向量和 Parikh 向量的不等式约束转变成关于Parikh 向量的不等式约束,然后基于 Petri 网库所是关于 Parikh 向量的不等式约束的观点构造控制器.最后将该方法与 Iordache 和 Moody 提出的方法作比较,实验结果显示该方法更简单、有效.

关键词： Petri网离散事件系统监控线性不等式约束 Parikh向量

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The Role of Multimodality Imaging Techniques on Differential Diagnosis of Precancerous Nodules and Hepatocellular Carcinoma

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2012年第3期1卷 67-72页

作者： Hui-jie Jiang Xiao-feng Li Department of Diagnostic Radiology University of Louisville School of Medicine Louisville USA Department of Radiology the Second Affiliated Hospital of Harbin Medical University Harbin China

In recent years, the incidence of hepatocellular carcinoma (HCC) has been increasing worldwide, and its high mortality seriously threatens public health. Early detection and treatment are crucial to improving the survival rate. Imaging examination widely used for the diagnosis of HCC and provides a non-invasive means of tumor visualization. The rapid development of medical imaging technology is expected to improve early-stage diagnosis rates for HCC. This article summarizes the methods for the differential diagnosis of premalignant dysplastic nodule (DN) and small hepatocellular carcinoma during the carcinogenesis of cirrhosis and reviews their application. In addition, a discussion on some recently patented medical imaging development was also presented.

关键词： Precancerous Nodules Small Hepatocellular Carcinoma CT MRI: Ultrasound

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Gabor滤波器的快速实现

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自动化学报 2007年第5期33卷 456-461页

作者：陈小光封举富北京大学信息科学技术学院智能科学系视觉与听觉信息处理国家重点实验室北京100871

本文提出了Gabor滤波器的两种快速实现方法．这两种方法首先把Gabor滤波器分解为多个不同方向上有着不同参数的一维高斯滤波器的组合,然后通过递归的方法分别实现这些高斯滤波器,从而实现Gabor滤波器．实验和分析结果表明,本文提出的Ga... 详细信息

本文提出了Gabor滤波器的两种快速实现方法．这两种方法首先把Gabor滤波器分解为多个不同方向上有着不同参数的一维高斯滤波器的组合,然后通过递归的方法分别实现这些高斯滤波器,从而实现Gabor滤波器．实验和分析结果表明,本文提出的Gabor滤波器的快速实现方法,不论是计算复杂度还是计算精度,都比基于卷积的标准实现方法有着更好的性能和效果．

关键词： Gabor滤波高斯滤波器非正交分解递归滤波快速算法

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HRB600钢筋的力学性能及其使用性能的试验研究

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建筑结构学报 2018年第S2期39卷 387-393页

作者：熊浩葛杰冯俊白洁中国建筑第八工程局有限公司上海200122

为了研究HRB600钢筋的使用性能,进行了钢筋拉伸试验、混凝土柱偏压、轴压试验和混凝土梁受弯试验。通过钢筋的拉伸试验和混凝土柱的偏压、轴压试验,确定了HRB600钢筋的屈服强度设计值,其中抗拉屈服强度设计值可取为520 MPa,抗压屈服强... 详细信息

为了研究HRB600钢筋的使用性能,进行了钢筋拉伸试验、混凝土柱偏压、轴压试验和混凝土梁受弯试验。通过钢筋的拉伸试验和混凝土柱的偏压、轴压试验,确定了HRB600钢筋的屈服强度设计值,其中抗拉屈服强度设计值可取为520 MPa,抗压屈服强度设计值可取为490 MPa(偏压)及400 MPa(轴压);通过对配置HRB600钢筋混凝土梁进行受弯试验,根据试验结果对GB50010—2010《混凝土结构设计规范》中最大裂缝宽度计算公式中的参数进行了研究,并提出了最大裂缝宽度公式修正建议。经修正后的最大裂缝宽度计算值与实测值吻合较好;通过对焊接接头和套筒连接的拉伸试验可知,两种连接方式基本都能充分发挥钢筋强度,但由于焊接接头可能会发生脆性破坏,因此当使用焊接接头前应先予以试验验证。

关键词：高强钢筋 HRB600 静力试验力学性能最大裂缝宽度

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基于杂交水稻叶片SPAD值的氮素营养诊断模型的初步构建

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中国稻米 2024年第2期30卷 5-12页

作者：任红军许桂玲冯跃华李杰王晓珂高钰琪由晓璇韩志丽李家乐贵州大学农学院贵阳550025 贵州大学山地植物资源保护与种质创新教育部重点实验室贵阳550025

为探明水稻叶片SPAD值的最佳测定叶位和最佳的SPAD值次级指标,并构建基于水稻叶片SPAD值的氮素营养诊断模型,开展以品种为主区,氮肥施用量为副区的双因素裂区设计试验。参试品种为Q优6号和宜香优2115,氮肥施用量设5个水平(纯N 0、75、15... 详细信息

为探明水稻叶片SPAD值的最佳测定叶位和最佳的SPAD值次级指标,并构建基于水稻叶片SPAD值的氮素营养诊断模型,开展以品种为主区,氮肥施用量为副区的双因素裂区设计试验。参试品种为Q优6号和宜香优2115,氮肥施用量设5个水平(纯N 0、75、150、225、300 kg/hm^(2)),分析叶片的敏感性、代表性和稳定性,并探讨SPAD值次级指标与施氮量和叶片含氮量之间,及叶片氮积累量与叶片含氮量和产量之间的关系。结果表明,叶片敏感性、代表性和稳定性大小顺序分别为L4(顶4叶)>L3(顶3叶)>L1(顶1叶)>L2(顶2叶)和L3>L4>L2>L1、L2>L3>L4>L1,可见,L3、L4可作为氮素营养诊断的共同理想指示叶。选择L3、L4的SPAD值几何平均数(GMSI34)作为最佳的SPAD值次级指标。由叶片氮积累量与产量和叶片含氮量的抛物线方程、一元线性回归方程,GMSI34与叶片含氮量的指数方程,求得拔节期、孕穗期、抽穗期的SPAD值次级指标的临界值(GMSI34_(临))分别为48.5、44.3和42.9,与实际获取的GMSI34实相比较,若GMSI34_(实)-GMSI34_(临)<0时,则表明水稻缺氮,需要追氮,若GMSI34_(实)-GMSI34_(临)≥0,则表明水稻氮营养充足,无需追氮。综上,基于杂交水稻叶片SPAD值的氮素营养诊断模型,可为杂交水稻高效氮肥管理提供技术支持。

关键词：杂交水稻叶位 SPAD值营养诊断模型

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Extraction of Robot Primitive Control Rules from Natural Language Instructions

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International Journal of Automation and computing 2006年第3期3卷 282-290页

作者： guang-Hong Wang Ping Jiang Zu-Ren feng Department of Information and Control Engineering Tongji University Shanghai 200092 China Department of Cybernetics and Virtual Systems University of Bradford Bradford BD7 1DP UK Department of Information and Control Engineering Tongji University Shanghai200092 China Systems Engineering Institute Xi＇an Jiaotong University Xi＇an 710049 China

A support vector rule based method is investigated for the construction of motion controllers via natural language training. It is a two-phase process including motion control information collection from natural language instructions, and motion information condensation with the aid of support vector machine （SVM） theory. Self-organizing fuzzy neural networks are utilized for the collection of control rules, from which support vector rules are extracted to form a final controller to achieve any given control accuracy. In this way, the number of control rules is reduced, and the structure of the controller tidied, making a controller constructed using natural language training more appropriate in practice, and providing a fundamental rule base for high-level robot behavior control. Simulations and experiments on a wheeled robot are carried out to illustrate the effectiveness of the method.

关键词： Support vector machines (SVMs) fuzzy neural networks motion primitives motion controller language instruction based training natural language programming.

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Imaging Reaction Dynamics of Y+SO2

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Chinese Journal of Chemical Physics 2020年第2期33卷 239-242,I0003页

作者： Dong Yan Yu-jie Ma Fang-fang Li Jia-xing Liu Guan-jun Wang feng-yan Wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Collaborative Innovation Center of Chemistry for Energy Materials(iChEM)Fudan UniversityShanghai 200433China

The reaction dynamics of yttrium atoms with sulfur dioxide molecules at a high collision energy of 36 kcal/mol was studied using time-sliced velocity map ion imaging,crossed molecular beam and laser-ablation *** product YO was detected via multiphoton ionization at various wavelengths in the region of 482-615 *** slice images of YO show a broad velocity distribution and forward-backward peaking angular *** forward scattering signal is stronger than its backward *** indicates that the reaction proceeds via an intermediate complex and the lifetime of the intermediate state is less than one rotational *** formation of complex suggests that electron transfer occurs in the oxidation reaction.

关键词： Time-sliced velocity map imaging Crossed-beam Laser ablation Metal atom reaction dynamics SO2

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Electro-optic and Photorefractive Properties of Doped Poly (N-Vinylcarbazole)

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Chinese Physics Letters 1997年第6期14卷 474-477页

作者： WANG Shu-feng HUANG Zhi-wen CHEN Zhi-jian GONG Qi-huang ZHANG Zhi-jie CHEN Hui-ying Department of Physics Mesoscopic Physics LaboratoryPeking UniversityBeijing 100871 Department of Chemistry Peking UniversityBeijing 100871

In this work,100μm-thick doped poly(N-vinylcarbazole)films with different contents of the electro-optic(EO)chromophore 2,5-dimethyl-4-(p-nitrophenylazo)anisole and plasticizer N-ethylcarbazole were prepared and sandwiched between two indium-tin oxide-covered glass *** EO measurements and two-beam-coupling experiments were performed by using a single mode(TEM00)He-Ne *** the EO coefficient and the gain for two-beam-coupling were found to be strongly depending on the content of plasticizer.

关键词： Photorefractive coupling beam

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